Castramid Tablet 10

Castramid 50 Tablet 10

Ipca Laboratories Pvt Ltd.

Strip of 10 Units

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MRP ~~₹464.13~~

₹380.59

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Composition

Bicalutamide (50 Mg)

Castramid 50 Tablet 10 is primarily used to manage advanced prostate cancer in adult men. This medication is a part of the nonsteroidal antiandrogens class of medicines.

Besides its main use, this tablet is also employed in combination with luteinising hormone-releasing hormone (LHRH) agonists, such as goserelin or leuprolide, to further slow the growth and spread of prostate cancer cells.

This medicine should be taken orally as directed by your doctor. Before beginning this medication, you should inform your doctor about any preexisting conditions or ongoing medications. If you experience any side effects while taking this medicine, immediately notify your doctor. Continue taking the medicine for the full duration prescribed by your doctor for optimal results.

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Castramid 50 Tablet 10 is used for the following:

Managing advanced prostate cancer in adult men
Reducing the effects of androgens like testosterone, which can stimulate the growth of prostate cancer cells.
Works in combination with luteinizing hormone-releasing hormone (LHRH) agonists to manage advanced prostate cancer more effectively.

Directions for Use of Castramid 50 Tablet 10

Follow these instructions while taking Castramid 50 Tablet 10:

Swallow the tablet whole with a glass of water.
Do not chew, divide, or crush the tablet.
Take it at the same time each day, either in the morning or evening.
Ensure that you take this medicine regularly as prescribed by your doctor, even if you are feeling well.
Do not stop taking this medicine without consulting your doctor first.

Castramid 50 Tablet 10 is taken orally.

Castramid 50 Tablet 10 may cause the following side effects:

Hot flashes
Breast pain
Fatigue
Impotence
Decreased libido: This means a reduced interest in sexual activities.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Castramid 50 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Hot flashes: Stay cool by wearing light clothing, using fans, and avoiding triggers like spicy foods or hot beverages.
Fatigue: Prioritise rest, maintain a regular sleep schedule, and incorporate light exercise to boost energy levels.

Castramid 50 Tablet 10 contains bicalutamide (50 mg), which has the following effects on the body:

Binding to Androgen Receptors: Bicalutamide competitively binds to androgen receptors in target tissues. These receptors are crucial as they allow androgens, male hormones like testosterone, to stimulate prostate cancer cell growth.
Blocking Androgens: By binding to these androgen receptors, bicalutamide effectively blocks the effect of these hormones on the cancer cells.
Slowing Cancer Growth: As a result of inhibiting androgens from stimulating the cancer cells, bicalutamide helps to slow down or stop the growth and spread of prostate cancer.

Pregnancy

Castramid 50 Tablet 10 is contraindicated during pregnancy. If you are pregnant or planning to conceive, it's crucial to discuss this with your doctor before starting this medicine.

Breastfeeding

Castramid 50 Tablet 10 is contraindicated for breastfeeding women. Consult your doctor to understand potential risks and benefits.

Alcohol

To be on the safe side, it's recommended to limit alcohol consumption while taking this medicine.

Liver

This medicine can cause serious liver problems. Caution is advised if you have any liver conditions, and it's best to discuss them with your doctor before starting Castramid 50 Tablet 10. Frequent liver function tests may be needed during treatment.

Kidney

It's good practice to consult your doctor if you have a history of kidney problems before starting this medicine.

Using Machines & Driving

Castramid 50 Tablet 10 may cause dizziness or drowsiness. Until you know how this medicine affects you, avoid driving or operating machinery.

Allergy

If you have any known allergies, inform your doctor before starting treatment with Castramid 50 Tablet 10. Some patients may experience allergic reactions such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat.

Children

Castramid 50 Tablet 10 is not indicated for use in children. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Castramid 50 Tablet 10 under medical supervision as they may be more susceptible to its side effects, especially those related to liver health. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Castramid 50 Tablet 10 interacts with the following medicines:

Blood thinning medications: Castramid 50 Tablet 10 can alter the effectiveness of medicines like warfarin, leading to an increased risk of bleeding.
Immune system medications: Cyclosporine, used to suppress the immune system after organ transplants, might interact with this medicine, causing changes in the body's response.
Sedatives: This medicine can affect the potency of sedatives such as midazolam and triazolam, potentially increasing their effects.

Drug-Food Interactions

There are currently no specific food interactions known with Castramid 50 Tablet 10.

Drug-Disease Interactions

Castramid 50 Tablet 10 interacts with the following diseases:

Liver disease: People with liver problems should exercise caution as Castramid 50 Tablet 10 could exacerbate their condition. Regular liver function tests may be necessary during treatment.

Daily Dose

You should take your daily dose of Castramid 50 Tablet 10 as instructed by your doctor. The dosage can vary based on factors such as the severity of your condition and how well you respond to the medicine. Always stick to the prescribed dosage and avoid exceeding it without consulting your doctor.

Over Dose

If you accidentally take more than the recommended dose of Castramid 50 Tablet 10, you might feel excessively tired or dizzy. Should these symptoms persist, please inform your doctor.

Missed Dose

If you forget to take your scheduled dose of Castramid 50 Tablet 10, take it as soon as you remember. However, if it's nearly time for the next dose, skip the missed one and continue with your regular dosage schedule. Don't increase your dosage without talking to your doctor.

Store Castramid 50 Tablet 10 at room temperature.
Keep the medicine in a dry place, away from light and moisture.
Always ensure the tablet container is tightly closed after use.
Keep out of reach of children.
Remember to check the expiry date before you take a dose.

Aim for a balanced diet rich in fruits, vegetables, lean proteins, and whole grains. This can help maintain overall health while managing prostate cancer.
Regular moderate physical activity can contribute to improved well-being and energy levels. However, always discuss your exercise plans with your doctor first.

Fact Box

Drug Category	Androgen Receptor Inhibitor
Therapeutic Category	Antineoplastic Agent
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Advanced Prostate Cancer

What is Castramid 50 Tablet 10 used for?

Castramid 50 Tablet 10 is used to manage advanced prostate cancer in men, alongside other medicines called luteinising hormone-releasing hormone (LHRH) agonists.

How does Castramid 50 Tablet 10 work?

This medicine works by blocking male hormones, like testosterone, which can stimulate the growth of prostate cancer cells, thereby managing the disease's progression.

Can I take Castramid 50 Tablet 10 at any time of day?

Yes, you can, but it's best to choose one time of day and consistently take the medicine at that time, either with or without food.

Is Castramid 50 Tablet 10 safe for everyone to use?

No. This medicine is not suitable for women or children. Men with liver problems should consult their doctor before starting this medication.

What are some potential side effects of Castramid 50 Tablet 10?

Side effects may include hot flashes, breast enlargement or tenderness, fatigue, impotence, decreased libido, and occasionally serious liver problems.

Are there any medicines that interact with Castramid 50 Tablet 10?

Yes, certain medicines including warfarin and calcium channel blockers may interact with this medicine. Always inform your doctor about all medicines you're currently taking.

What should I do if I suspect an overdose of Castramid 50 Tablet 10?

If you suspect an overdose, seek immediate medical help. Overdose symptoms can include fatigue, weakness, and dizziness.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

125, Charkop Rd, Kandivali, Charkop, Charkop Industrial Estate, Kandivali West, Mumbai, Maharashtra 400067

Country of origin: INDIA

References

AstraZeneca Pharmaceuticals LP. (1995). Highlights of prescribing information for Casodex [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020498s028lbl.pdf
Bicalutamide. (2014, February 10). Cancer.gov. https://www.cancer.gov/about-cancer/treatment/drugs/bicalutamide
PubChem. (n.d.). Bicalutamide. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Bicalutamide
Bicalutamide: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01128
Bicalutamide: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a697047.html

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