Ceftum 250 Mg Tablet 4

Ceftum 250 Tablet 4

Glaxosmithkline Pharmaceuticals Ltd.

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Composition

Cefuroxime (250 Mg)

Strength:

250 MG 500 MG 125 MG

Ceftum 250 mg tablets are commonly prescribed antibiotics for treating bacterial infections. Ceftum 250 mg tablets belong to the cephalosporin class of antibiotics, known for their effectiveness against many bacterial infections. The antibiotic works by inhibiting the growth of bacteria. It does this by interfering with the formation of the bacterial cell wall, ultimately destroying the bacterial cells.

Ceftum 250 mg tablets are commonly prescribed for treating bacterial infections of upper respiratory tract infections such as tonsillitis, pharyngitis, sinusitis, and otitis media. This medication effectively treats lower respiratory tract infections such as pneumonia and acute exacerbations of chronic bronchitis. It can also aid in curing urinary tract infections such as pyelonephritis, cystitis, and urethritis. It is equally effective in treating skin and soft tissue infections like cellulitis, impetigo, and wound infections.

As with any medication, Ceftum 250 mg tablets may cause side effects. Notifying your healthcare provider if you experience any severe or persistent side effects is essential.

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Pharyngitis: Pharyngitis and tonsillitis are infections that cause swelling and soreness in the throat and tonsils. If the infection affects both the throat and the tonsils, it is called pharyngotonsillitis. Ceftum 250 mg tablets treat pharyngitis, tonsillitis, and pharyngotonsillitis.
Sinusitis: Sinusitis is the swelling of membranes that line your nose and surrounding sinuses. It is often caused by bacteria and, sometimes, viruses and fungi. You may experience a stuffy nose and pain or pressure behind your eyes, nose, cheeks, or forehead. Ceftum 250 mg tablets treat bacterial sinusitis and provide relief in three to eight weeks.
Bronchitis: Bronchitis is the swelling and irritation of bronchial tubes that regulates air passage in the lungs. Ceftum 250 mg tablets is used to treat bronchitis caused by bacteria. It is also used to treat a sudden worsening of chronic bronchitis (long-term bronchi inflammation) and subsequent bronchitis episodes.
Skin and soft tissue infections: Skin and soft tissue infections occur when bacteria invade the skin and its supporting structures. Ceftum 250 mg tablets treat all skin infections, including abscesses caused by bacteria.
Urinary tract infections: An infection in your urinary system (kidneys, bladder, ureters, or urethra) is called a urinary tract infection (UTI). UTIs are the most common infections in humans, and women are at greater risk of getting this infection. Bacteria cause UTIs and, in some cases, viruses or fungi. Ceftum 250 mg tablets treat urinary tract infections caused by bacteria.
Lyme disease: Lyme disease is an infection resulting from Borrelia burgdorferi. This infection is spread to humans through the bite of infected black-legged ticks that carry the bacteria. This condition can be treated in a few weeks by using antibiotics. Ceftum 250 mg tablets treat Lyme disease.
Middle Ear Infections (Media Otitis): Ceftum 250 mg tablets can treat middle ear infections common in children. The medication is effective against many bacteria that cause middle ear infections, including Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis.

Directions for Use of Ceftum 250 Tablet 4

Ceftum 250 mg tablets should be taken as your doctor recommends.
Swallow it as a whole with water after your meal to avoid stomach discomfort.
Do not cut, break or chew the medicine.
It would be best to take it at a fixed time for optimal results.
It would be best if you consumed what your doctor prescribes.

Ceftum 250 mg tablet is administered orally, making it a convenient and less invasive treatment option for patients.

Here are the common side effects of Ceftum 250 mg tablets:

Headache is a common side effect of Ceftum 250 mg tablets; it is thought to be related to the drug's impact on the central nervous system.
Dizziness: Ceftum 250 mg tablets can cause dizziness as a side effect, leading to lightheadedness or vertigo.
Stomach upset: Ceftum 250 mg tablets can cause stomach upset, including nausea, vomiting, abdominal pain, and diarrhoea. These symptoms usually resolve after the completion of the antibiotic therapy.
Unpleasant taste in the mouth: This is a common side effect of Ceftum 250 mg tablets. Patients may experience a metallic or bitter taste in the mouth during treatment.
Fungal skin infection: Ceftum 250 mg tablets can lead to the overgrowth of Candida, a type of fungus, which can cause skin and mucous membrane infections, including thrush, diaper rash, and vaginal yeast infection.
Eosinophilia or increased WBC: Ceftum 250 mg tablets can cause an increase in eosinophils, a type of white blood cell linked to the immune response. This increase can be benign, but in rare cases, it can lead to eosinophilic pneumonia.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing Ceftum 250 mg tablets. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Ceftum 250 mg tablets contain cefuroxime axetil, an antibiotic that stops bacteria from growing and causes them to die. It does this by blocking a process necessary for building the outer layer of the bacteria. This causes the bacteria to weaken and eventually break apart. Cefuroxime axetil is converted to cefuroxime in the body, which is the active form of the drug. Cefuroxime is effective against many different types of bacteria, including those that lead to pneumonia, ear infections, and urinary tract infections.

Pregnancy

Since, No adequate and well-controlled studies of Cefuroxime use in pregnant women, it is recommended to use Ceftum 250 mg tablets cautiously during pregnancy.

Breastfeeding

Ceftum 250 mg tablets should be used with caution during breastfeeding. Cefuroxime may pass into breast milk and cause harm to the nursing baby. Therefore, avoiding using Ceftum 250 mg tablets during breastfeeding is advisable.

Alcohol

The consumption of alcohol should be avoided when using Ceftum 250 mg tablets as it may increase the risk of specific side effects such as dizziness, drowsiness, and liver damage.

Liver

Ceftum 250 mg tablets should be used carefully in patients with liver problems. Since the liver primarily eliminates cefuroxime, a decrease in liver function can cause higher levels of the drug in the blood, increasing the risk of side effects, especially those affecting the central nervous system. Please consult your physician before taking Ceftum 250 mg tablets.

Kidney

There is little data on using Ceftum 250 mg tablets in patients with kidney dysfunction. Please consult your physician.

Using Machines & Driving

Ceftum 250 mg tablets may lead to dizziness or confusion. Do not drive a vehicle or operate machinery after taking this medicine.

Allergy

Patients with a known allergy to cefuroxime or other cephalosporin antibiotics should not use Ceftum 250 mg tablets. Inform your doctor and seek emergency medical assistance.

Children

Ceftum 250 mg tablet is not advised for children under 12. Consult the paediatrician for advice to treat the infection effectively.

Older Patients

Dosage adjustments may be necessary based on age and kidney function. Ceftum 250 mg tablets are generally well-tolerated in older patients. However, older patients may be more prone to specific side effects, particularly those affecting the central nervous system.

Drug-Drug Interactions

Here are some drug-drug interactions that should be considered when using Ceftum 250 mg tablets:

Antacid: Ceftum 250 mg tablets should not be taken with antacids, omeprazole or other medicines that reduce gastric acidity as they can reduce the absorption of cefuroxime.
Immuno-suppressing drugs: Ceftum 250 mg tablets may interact with immuno-suppressing drugs such as mycophenolate or mycophenolic acid, which are used to prevent organ rejection in transplant patients. These drugs can reduce the effectiveness of cefuroxime, and hence, they should be avoided or used with caution.
Medicines for reducing uric acid: Ceftum 250 mg tablets can interact with probenecid, which reduces uric acid levels in patients with gout. Probenecid can increase the levels of cefuroxime in the bloodstream, leading to an increased risk of side effects.
Typhoid and BCG vaccines: Ceftum 250 mg tablets can interfere with the effectiveness of typhoid and BCG vaccines. Therefore, avoid these vaccines while taking Ceftum 250 mg tablets.

Drug-Food Interactions

Ceftum 250 mg tablets do not have significant drug-food interactions. However, some drug-food interactions are reported when using Ceftum 250 mg tablets:
To minimise the risk of gastrointestinal adverse effects, take Ceftum 250 mg tablet with food.
Grapefruit juice may interfere with a person's other medications and Ceftum 250 mg tablets. Grapefruit juice includes chemicals that can disrupt the metabolism of certain drugs, resulting in higher levels of the medication in the bloodstream and an increased risk of side effects.
Mineral supplements like calcium may also interact with Ceftum 250 mg tablets. Cefuroxime can bind to calcium, decreasing its absorption and efficacy. As a result, it is advised to avoid taking calcium supplements within 2 hours of using Ceftum 250 mg pills.

Drug-Disease Interactions

Here are the drug-disease interactions for Ceftum 250 mg tablets:

Colitis: Ceftum 250 mg tablets may worsen the signs of colitis, an inflammatory colon condition. Patients with a history of colitis should use Ceftum 250 mg tablets with caution, as it may increase the risk of developing antibiotic-associated diarrhoea, which can be severe.
Kidney disease: Ceftum 250 mg tablets should be used cautiously in patients with kidney disease and patients on dialysis. The dose of Ceftum 250 mg tablets may need to be adjusted in patients with severe kidney disease, as cefuroxime is eliminated primarily by the kidneys.
Patient planning for ferricyanide tests: Patients taking Ceftum 250 mg tablets may experience a false positive reaction in specific laboratory tests for glucose in urine using ferricyanide. Therefore, patients undergoing these tests should inform their healthcare provider about their medication use.
Liver disease: Ceftum 250 mg tablets should be used judiciously in patients with liver disease. The liver primarily eliminates Cefuroxime and a decrease in liver function can lead to higher levels of cefuroxime in the bloodstream, increasing the risk of side effects.
Epilepsy: Ceftum 250 mg tablets may lower the seizure threshold in some patients, leading to an increased risk of seizures.
Diarrhoea: Ceftum 250 mg tablets may cause diarrhoea, which can be severe. Patients with a history of diarrhoea should use Ceftum 250 mg tablets with caution, as it may increase the risk of developing antibiotic-associated diarrhoea, which can be severe.

Daily Dose

The recommended dose of Ceftum is 250 mg once daily, with food, as directed by your doctor. The dosage may change based on individual factors such as the severity of the condition and response to treatment. It is essential to follow the suggested dosage and not exceed it without consulting your doctor.

Over Dose

If you or someone else takes excessive Ceftum 250 mg tablets by accident, it is essential to take immediate medical attention from your doctor or nearby hospital. An overdose's symptoms include brain damage and may cause headache, dizziness and stomach upset.

Missed Dose

If you forgot to take Ceftum 250 mg tablets, take it as soon as you recall or as your health care provider instructed. If the time for the next dosage is close, skipping the missed one is recommended now and resume your regular dosage pattern. Never increase your dosage without consulting your doctor.

Store Ceftum 250 mg tablets at room temperature (15-25ºC).
Please protect it from light and moisture.
Keep Ceftum 250 mg tablets away from children.
Do not use the Ceftum 250 mg tablet after the expiry date has passed.

Eat a diet rich in fibre-rich foods, such as whole grains, legumes, berries, broccoli, peas, and bananas.
The digestively helpful bacteria in the stomach may be disturbed by antibiotics. As a result, probiotic-rich meals like buttermilk and yoghurt are advised.
Don't consume alcohol or smoke cigarettes.
Avoid caffeine: Caffeine-containing beverages like coffee, tea, and energy drinks should be used in moderation. The likelihood of adverse consequences like anxiety, restlessness, and irregular heartbeat is increased by caffeine.
Maintain a balanced diet: To strengthen your immune system, consume a diet high in vitamins and minerals. Eat less food that is heavy in salt, sugar, and fat.
Wash your hands frequently to practise good hygiene and stop the spread.

To avoid developing antibiotic resistance, finish the entire course of treatment with Ceftum 250 mg tablets. If you experience any adverse effects, speak with your doctor.
Taking Ceftum 250 mg pills with meals or just after eating is advised. This improves the medication's absorption and lowers the risk of experiencing gastrointestinal side effects such as nausea, vomiting, diarrhoea, and stomach discomfort.
Ceftum 250 mg tablets should be stopped immediately if you suffer from a rash, itchy skin, facial or oral swelling, or breathing problems. Also, notify your doctor right once

Fact Box

Drug Category	Intermediate Spectrum {Second generation cephalosporins}
Therapeutic Category	Antibiotic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Bacterial infections

Is Ceftum 250 mg tablet a strong antibiotic?

Yes, Ceftum 250 mg tablet (cefuroxime) is a moderately strong, broad-spectrum antibiotic in the cephalosporin class that is effective against many bacterial infections. However, its effectiveness depends on the specific infection being treated and individual patient factors.

How many days will the Ceftum 250 mg tablet be taken?

Most infections require seven to ten days for treatment with Ceftum 250 mg tablets. However, this can vary depending on the kind and severity of the illness. Even if you start feeling better before the medicine is finished, sticking to your healthcare professional's exact dosage and treatment period is critical.

How quickly does Ceftum 250 mg tablet work?

Ceftum 250 mg tablets may take a few days to start working, and noticeable improvements may be seen within 24-48 hours of treatment. However, antibiotics do not work immediately and may take time to eradicate the bacterial infection. It is essential to continue taking the medication as prescribed by your healthcare provider, even if you start feeling better, to ensure complete eradication of the bacteria and prevent the recurrence of infection. If you have concerns about the medication's effectiveness, it is best to consult your healthcare provider for specific advice based on your circumstances.

Can a Ceftum 250 mg tablet be taken twice a day?

Ceftum 250 mg tablet should be taken as long as the doctor prescribes you based on the type and severity of the infection being treated and other individual patient factors. It is critical to adhere to the recommended dosage and frequency of therapy to ensure the medication's effectiveness and reduce the danger of side effects.

Does Ceftum 250 mg tablet cause weakness?

Weakness is a potential side effect of Ceftum 250 mg tablet, but it is not typical. Other possible side effects of Ceftum may include nausea, vomiting, diarrhoea, abdominal pain, headache, dizziness, and rash. While taking Ceftum 250 mg tablet, consulting with your healthcare provider is essential. They can evaluate your symptoms and determine whether medication or treatment plan adjustments are necessary.

Is Ceftum 250 mg tablet stronger than Augmentin?

Ceftum 250 mg tablet and Augmentin are antibiotics that are effective against a wide range of bacteria, but they belong to different classes of antibiotics and work in slightly different ways. It is difficult to say which antibiotic is "stronger" as their effectiveness may vary depending on the specific type and severity of the treated infection and individual patient factors. Ultimately, the choice of antibiotic will depend on the specific circumstances and the judgment of the prescribing healthcare provider.

Is Ceftum 250 mg tablet safe for kidney disease?

Ceftum 250 mg tablet can be safe for individuals with kidney disease, but dosage adjustments may be necessary. Patients with impaired kidney function may require a lower dose or a longer interval between doses to avoid accumulating the medication in the body. Talk to your doctor immediately if you have any unusual side effects while taking the drug. Also, adhere to the dosage and schedule that have been given.

Does Ceftum 250 mg tablet cause constipation?

Constipation is a rare side effect of Ceftum 250 mg tablet, but any medication can potentially cause gastrointestinal symptoms. If you notice any unusual symptoms while using Ceftum 250 mg tablet, you must speak with your doctor.

What foods should you avoid while taking Ceftum 250 mg tablet?

You should avoid taking grapefruit juice as it may interact with other medications a person may take, along with Ceftum 250 mg tablets. Also, you should avoid dietary supplements containing minerals like calcium may also interact with Ceftum 250 mg tablets.

Can Ceftum be taken for UTI?

Yes, Ceftum (cefuroxime) 250 mg tablet can treat urinary tract infections (UTIs) caused by susceptible bacteria. To ensure the medication's effectiveness and reduce the danger of adverse effects, it is crucial to adhere to the recommended dosage and course of treatment from your healthcare professional.

What generation is Ceftum 250 mg tablet?

Ceftum 250 mg Tablet contains cefuroxime which is a second-generation cephalosporin.

Last Updated On 17 Feb. 2024 | 8:17AM (IST)

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 5 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 10 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

No 252, Dr Annie Besant Rd, Worli Shivaji Nagar, Worli, Mumbai, Maharashtra 400018

Country of origin: INDIA

References

KD Tripathi. Second-generation cephalosporins. Essentials of Medical Pharmacology. Eighth edition. Page - 777.
Patient information. (n.d.). Retrieved February 17, 2024, from https://india-pharma.gsk.com/media/6357/ceftum-tablets.pdf

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