Cellcept 500 Mg Tablet 10

Cellcept 500mg Tablet 10

Roche

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Composition

Mycophenolate Mofetil (500 Mg)

Strength:

500 MG 250 MG

Cellcept Tablet is a medication that is chiefly used to prevent the body from rejecting a transplanted organ, such as a kidney, heart, or liver. It falls under the category of immunosuppressants.

In addition to its primary use, this medicine mitigates the risk of the transplant being attacked and rejected by your body's immune system. It plays an integral role in your overall treatment plan to maintain the health and functionality of the transplanted organ.

Before starting this medication, it is crucial to consult with your doctor about the right dosage and frequency. Before starting, inform your doctor about any pre-existing conditions or ongoing medications. Any side effects should be promptly reported to your doctor for immediate attention. To achieve optimum results, continue taking this medication for the duration prescribed by your doctor.

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Cellcept Tablet is used for the following conditions:

Preventing organ rejection after a kidney transplant
Reducing the risk of organ rejection following a heart transplant
Decreasing chances of liver transplant rejection

Directions for Use of Cellcept 500mg Tablet 10

Here are the steps to follow while taking a Cellcept Tablet:

Swallow the tablet whole with a glass of water.
Do not crush, chew, or cut the tablet.
Take the medicine on an empty stomach, either 1 hour before or 2 hours after meals.
Always adhere to your doctor's prescribed dose, and never take more without consulting your doctor.
It's crucial not to stop taking this medicine abruptly. Always consult your doctor before discontinuing.

Cellcept Tablet is taken orally.

Side Effects of Cellcept 500mg Tablet 10

Cellcept Tablet may have the following side effects:

Constipation
Nausea
Diarrhoea
Vomiting
Stomach upset
Gas
Tremor
Drowsiness
Trouble sleeping

Managing the Side Effects:

Most side effects are temporary and generally harmless and resolve upon discontinuing the use of Cellcept Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Try taking Cellcept Tablet with food to lessen this effect.
Trouble sleeping: If this medicine causes you difficulty sleeping, consider taking it in the morning rather than before bedtime.

Cellcept Tablet contains mycophenolate mofetil (500 mg), and its activity in your body can be summarised as follows:

Conversion to active metabolite: After you take Cellcept Tablet orally, it gets quickly transformed into an active metabolite called mycophenolic acid (MPA).
Inhibition of IMPDH: MPA acts as a potent inhibitor of an enzyme called inosine monophosphate dehydrogenase (IMPDH). IMPDH plays a pivotal role in the production of certain substances required for DNA synthesis.
Suppression of immune response: By inhibiting IMPDH, MPA reduces these substances in T and B lymphocytes (types of white blood cells). This action suppresses their growth and function, leading to a weakened immune response against the transplanted organ.

Pregnancy

Cellcept Tablet can cause harm to your unborn baby when administered during pregnancy. If you are pregnant or plan to conceive, it's best to discuss this with your doctor before you begin using this medicine.

Breastfeeding

Breastfeeding is not recommended while taking Cellcept Tablet. The active ingredient, mycophenolate mofetil, may pass into breast milk and could potentially harm your nursing baby. If you're breastfeeding, consult your doctor before using this medicine.

Alcohol

The interaction of Cellcept Tablet with alcohol is unknown. It's wise to consult your doctor.

Liver

If you have liver problems, it's important to discuss this with your doctor before starting Cellcept Tablet. This medicine could affect liver function.

Kidney

If you have a history of kidney issues, caution is advised before using Cellcept Tablet. It is recommended that you consult your doctor before taking this medicine.

Using Machines & Driving

Cellcept Tablet might cause dizziness or drowsiness in some patients. If you experience these side effects, avoid driving or operating heavy machinery until you feel well again.

Allergy

If you are allergic to mycophenolate mofetil in Cellcept Tablet, avoid taking this medicine. An allergic reaction might include rash, itching, breathing difficulties, or swelling of the face, lips, throat or tongue.

Children

Cellcept Tablet is not recommended for use in children due to limited safety and efficacy data. Always consult your doctor before giving this medicine to a child under 18 years of age.

Older Patients

Older patients should take Cellcept Tablet under medical supervision, as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Interactions of Cellcept 500mg Tablet 10

Drug-Drug Interactions

Cellcept Tablet interacts with the following medicines:

Immune system medications: Medicines such as natalizumab and rituximab that weaken the immune system may increase your risk of infection when taken with Cellcept Tablet.
Antacids: Antacids containing magnesium or aluminium can reduce the amount of mycophenolate mofetil your body absorbs. Always take these at least 2 hours after taking Cellcept Tablet.

Drug-Food Interactions

There are no specific food interactions with Cellcept Tablet. However, for best absorption, it's always a good idea to take it on an empty stomach.

Drug-Disease Interactions

Cellcept Tablet interacts with the following diseases:

Infections: As this medicine may lower your ability to fight infections, any existing infections might worsen.
Neurological conditions: Cellcept Tablet use is associated with a rare risk of a brain infection called progressive multifocal leukoencephalopathy (PML). If you have any neurological conditions, consult your doctor before taking this medicine.
Cancer: This medication may increase the risk of developing certain cancers, including lymphoma and skin cancer. Discuss your personal and family medical history with your doctor before starting this medication.

Daily Dose

For Cellcept Tablet, follow the daily dosage as directed by your doctor. This may vary based on individual factors like the severity of your condition and how you respond to the medicine. It's crucial not to alter the prescribed dose without consulting your doctor.

Over Dose

Overdosing on Cellcept Tablet may lead to side effects like constipation, nausea, headache, diarrhoea, vomiting, and dizziness. If you suspect an overdose or observe these symptoms persisting, please inform your doctor.

Missed Dose

If you've missed a dose of Cellcept Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the one you missed and carry on with your regular schedule. Avoid increasing your dose without first discussing it with your doctor.

Store Cellcept Tablet at room temperature, ideally not above 25°C.
Keep the medicine in its original container to protect it from light.
Make sure the storage area is out of reach of children.
Always use your medicine before its expiry date.

If you're taking Cellcept Tablet after an organ transplant, maintaining a healthy diet is crucial. Include plenty of fruits, vegetables, lean proteins, and whole grains in your meals. This can support your immune system and overall health.
Regular moderate exercise can also help improve your strength and energy levels after a transplant. However, always consult your doctor before starting any new exercise routine.

Fact Box

Drug Category	IMPDH Inhibitor
Therapeutic Category	Immunosuppressant
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Organ Rejection Prevention

What is the function of Cellcept Tablet?

Cellcept Tablet is an immunosuppressant medication that helps prevent organ rejection after a kidney, heart, or liver transplant.

How does Cellcept Tablet work in our body?

It contains mycophenolate mofetil, which suppresses the immune response against the transplanted organ by inhibiting certain cells' activity involved in immune reactions.

Can Cellcept Tablet be taken with other medicines?

Yes, it's usually taken with other immunosuppressants. However, certain medicines can interact with it, so always consult your doctor about all medications you're taking.

What precautions should I take while using Cellcept Tablet?

Monitor for signs of infection and neurological symptoms. Limit sun exposure and use effective contraception during treatment and after stopping.

What if I miss a dose of my Cellcept Tablet?

Take the missed dose as soon as you remember unless it's nearly time for the next one. In this case, skip the missed dose; don't double up.

Is it safe to take Cellcept Tablet during pregnancy?

No, it can cause harm to the foetus. Effective contraception should be used during treatment.

Can I breastfeed while taking Cellcept Tablet?

No, breastfeeding is not advised during treatment as the active ingredient can potentially cause adverse reactions in nursing infants.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

HOUSE NO. 220, PKT-8 SECTOR-22, ROHINI, NEAR BAJAJ PROPERTY Delhi North WestIN110086

Country of origin: INDIA

References

U.S. National Library of Medicine. (2022). Mycophenolate: MedlinePlus Drug Information. MedlinePlus. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a601081.html
Inhibitors of inosine 5′-monophosphate dehydrogenase as emerging new generation antimicrobial agents. (1, August). PubMed Central (PMC). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727467/
IMPDH inhibition activates TLR‐VCAM1 pathway and suppresses the development of MLL‐fusion leukemia. (n.d.). PubMed Central (PMC). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832838/

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