Clindakem A 011 Gel 20 Gm

Clindakem A Gel 20gm

Alkem Laboratories Ltd.

Tube of 20 GM

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MRP ~~₹181~~

₹90.32

₹9.05/GM

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Composition

Adapalene (0.1 %) + Clindamycin (1 %)

Clindakem A Gel is chiefly used in the management of acne vulgaris for those aged 12 and above. This combination medicine falls under the category of topical antibiotic and retinoid-like compounds.

The unique formulation of this does more than just manage acne; it acts against the growth of P. acnes bacteria, a primary cause of acne, and decreases inflammation on the skin. This dual-action approach makes it an effective solution for individuals dealing with persistent acne issues.

Before starting on this, it's crucial to consult your doctor who will guide you on the correct dosage and frequency, tailored to your condition. It's equally important to inform your doctor about any pre-existing conditions or ongoing medications you're on. Any side effects noticed while using this medicine should be reported to your doctor without delay. Ensure that you continue using the medicine for as long as it has been prescribed by your doctor.

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Clindakem A Gel is used to treat acne, which appears as spots or pimples on your face, chest, or back. It helps manage acne vulgaris by reducing pimples caused by clogged hair follicles. The gel also controls inflammation, reducing redness and swelling, and inhibits the growth of P. acnes bacteria associated with acne.

Directions for Use of Clindakem A Gel 20gm

Use Clindakem A Gel as outlined below:

Begin by cleaning and drying the affected area of your skin.
Apply a thin film of Clindakem A Gel to the affected areas on your face or trunk once daily after washing.
Avoid application near your eyes, lips, or on broken skin.
Wash your hands thoroughly after applying the gel.
Always consult your doctor for advice on how to use this medication properly.

Clindakem A Gel is applied topically.

Using Clindakem A Gel may lead to certain side effects. These include:

Pruritus: This is a medical term for intense itching.
Burning sensation
Erythema: This refers to redness of the skin.
Scaling: Your skin might peel or flake in the area where you've used the gel.
Dryness
Photosensitivity: Sensitivity to sunlight can increase, causing sunburn more easily.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Clindakem A Gel. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips to manage a couple of common side effects:

Burning sensation: Try applying this gel at bedtime if it causes a burning sensation during the day.
Photosensitivity: Avoid direct sunlight while using Clindakem A Gel. Wear sunscreen and protective clothing when going out in daylight.

Clindakem A Gel is a potent combination medicine with two active ingredients working together to manage acne:

Clindamycin (1%): Belonging to the lincosamide antibiotic class, clindamycin works by inhibiting bacterial protein synthesis at the ribosomal level through its binding to the 50S ribosomal subunit. It exhibits activity against Propionibacterium acnes, a bacterium widely associated with acne vulgaris.
Adapalene (0.1%): This retinoid-like compound attaches itself to specific retinoic acid nuclear receptors in your body. While its precise mode of action is not entirely understood, it is believed to regulate the differentiation of follicular epithelial cells, leading to a decrease in microcomedone formation.

Pregnancy

If you are pregnant or planning to conceive, it's best to consult your doctor before using Clindakem A Gel.

Breastfeeding

While breastfeeding, caution is advised when using Clindakem A Gel. It is recommended to discuss this with your doctor.

Alcohol

Interactions between Clindakem A Gel and alcohol are rare since it's a topical application. However, always discuss your alcohol consumption with your doctor.

Liver

If you have liver issues, it's wise to consult your doctor before using Clindakem A Gel.

Kidney

Before using Clindakem A Gel, if you have a history of kidney problems, it would be prudent to consult your doctor.

Using Machines & Driving

Clindakem A Gel is a topical medicine and it doesn't usually affect your ability to drive or operate machinery.

Allergy

If you have a history of allergies or hypersensitivity reactions to clindamycin or lincomycin, or any components of the gel, Clindakem A Gel is contraindicated.

Children

Clindakem A Gel should not be applied to children under 12 years of age. For those above 12, always consult a doctor before use.

Older Patients

Older patients may need extra caution when using Clindakem A Gel due to potential effects on liver or kidney health. Your doctor will guide you based on your health status if you are above 70 years of age.

Drug-Drug Interactions

Clindakem A Gel interacts with the following medicines:

Topical Acne Treatments: If you're using other topical acne treatments, be careful. Using them together with Clindakem A Gel might cause skin irritation due to their combined effects.
Benzoyl Peroxide Products: When used alongside Clindakem A Gel, products containing benzoyl peroxide may cause temporary yellow or orange discolouration of the skin.

Drug-Food Interactions

No specific food interactions with Clindakem A Gel have been reported. However, always follow your doctor's advice regarding your diet while using this medication.

Drug-Disease Interactions

Clindakem A Gel interacts with the following diseases:

Hypersensitivity: If you've ever had an allergic reaction to clindamycin or lincomycin, or any component of the gel, avoid using Clindakem A Gel.
Gastrointestinal Disorders: People who have had regional enteritis, ulcerative colitis, or antibiotic-associated colitis should not use this gel as it might worsen their condition.

Daily Dose

Your doctor will prescribe the daily dosage of Clindakem A Gel. This is based on the severity of your acne and how you respond to the medication. Always follow your doctor's instructions and never exceed the prescribed dose without consulting your doctor.

Over Dose

An overdose of Clindakem A Gel may cause discomforting symptoms such as skin irritation or excessive dryness. If you accidentally apply more than instructed, remove the excess gel and rinse the area with water. If you notice any persisting discomfort, please inform your doctor.

Missed Dose

If you forget to apply Clindakem A Gel at your usual time, do so as soon as you remember. However, if it's nearly time for your next application, skip the missed one and carry on with your regular schedule. Do not double up doses without checking with your doctor.

Store Clindakem A Gel in a cool, dry place where the temperature is below 30°C.
Protect this medication from direct light; avoid freezing it.
Keep Clindakem A Gel out of reach and sight of children.

Maintain a balanced diet with plenty of fruits and vegetables to boost your skin's health. Healthy skin can better manage acne.
Try to limit your intake of oily and junk food, as they can trigger or worsen acne. Regular exercise can also help manage stress levels, which might contribute to acne breakouts. Always consult your doctor for tailored advice.

Fact Box

Drug Category	Retinoid-like, Antibacterial
Therapeutic Category	Acne management
Available Dosage Types	Gel
Habit Forming	No
Ailment	Acne vulgaris

What is Clindakem A Gel used for?

Clindakem A Gel is a topical medication used to manage acne vulgaris in patients who are 12 years and older by reducing inflammation and bacterial growth.

How does Clindakem A Gel work?

Clindakem A Gel combines adapalene and clindamycin. Adapalene helps prevent acne formation, while clindamycin, an antibiotic, stops the growth of bacteria associated with acne.

How should I apply Clindakem A Gel?

Apply a thin layer of Clindakem A Gel to the affected areas once daily after washing. Be careful to avoid your eyes, lips, and any broken skin.

Can Clindakem A Gel cause skin irritation?

Yes, Clindakem A Gel might cause skin irritation such as redness, scaling, dryness, stinging or burning. Use with caution if you have sensitive skin.

Can I use other acne treatments with Clindakem A Gel?

Using other topical acne treatments may increase skin irritation. If you plan to use another product alongside this gel, consult your doctor first.

Is it safe to use Clindakem A Gel during sun exposure?

Sun exposure should be minimised during treatment as this gel can cause photosensitivity. When outdoors, use sunscreen and wear protective clothing over treated areas.

What should I do if I accidentally swallow some Clindakem A Gel?

If you accidentally ingest Clindakem A Gel, get immediate medical assistance as it can lead to systemic side effects when absorbed in large amounts.

Last Updated On 25 Sep. 2024 | 10:04AM (IST)

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Alkem House, Senapati Bapat Marg, Lower Parel, Mumbai Maharashtra- 400013

Country of origin: INDIA

References

Adapalene: MedlinePlus Drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a604001.html
Clindamycin Phosphate Gel USP, 1% for external use. (n.d.). https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=b46941a9-e75f-48f7-b426-03f307499713&type=display
Galderma Laboratories, L.P. (2022). DIFFERIN gel [Topical Treatment]. In Full Prescribing Information (pp. 1–17). https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/021753s011lbl.pdf
U.S. Food and Drug Administration. (2000). Approval letter adapalene and clindamycin phosphate. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2000/50782LTR-LBL.PDF
Clindamycin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.-b). DrugBank. https://go.drugbank.com/drugs/DB01190

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