Clopivas Ap 15075 Mg Tablet 15

Clopivas Ap 150 Tablet 15

Cipla Ltd.

Strip of 15 Units

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Composition

Aspirin (150 Mg) + Clopidogrel (75 Mg)

Clopivas AP 150 Tablet is primarily used to prevent heart attacks, strokes, and other cardiovascular events in individuals who are at high risk. This product is a combination medication, belonging to the class of antiplatelet agents.

Besides its main use, this tablet also manages conditions like acute coronary syndrome and unstable angina. It plays a crucial role in preventing the formation of blood clots following certain procedures such as coronary artery bypass graft and percutaneous coronary intervention.

Before starting this medicine, it's crucial you consult your doctor for the correct dosage and frequency. It's also important to inform your doctor about any existing medical conditions or current medications you're on. If you experience any side effects while using this medicine, let your doctor know promptly. Remember to continue taking this medicine for the exact duration prescribed by your doctor for maximum benefit.

Clopivas AP 150 Tablet is used in the following scenarios:

Prevention of heart attacks in those who are at high risk or have a history of such events
Avoidance of strokes for patients with a high likelihood or past incidents
Management and control of acute coronary syndrome and unstable angina
Preventing blood clots after certain procedures like coronary artery bypass graft and percutaneous coronary intervention.

Directions for Use of Clopivas Ap 150 Tablet 15

Here's how you should take Clopivas AP 150 Tablet:

Swallow the tablet whole, without crushing, chewing, or breaking it.
You can take this medicine with or without food.
It's crucial to take this medicine regularly as directed by your doctor for optimal benefits.
Don't stop taking this medicine without consulting your doctor first.

Clopivas AP 150 Tablet is taken orally.

Side Effects of Clopivas Ap 150 Tablet 15

Clopivas AP 150 Tablet may cause the following side effects:

Gastrointestinal disturbances: This could include symptoms like stomach discomfort, bloating or gas.
Bleeding: This might be more noticeable than usual, such as nosebleeds or gums bleeding when you brush your teeth.
Bruising: You may notice bruises appearing more easily or taking longer to fade.
Dizziness
Headache

Managing the Side Effects:

Most side effects are temporary and generally harmless, and they resolve when you discontinue using Clopivas AP 150 Tablet. However, if you experience serious side effects or worsening symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Gastrointestinal disturbances: Try taking Clopivas AP 150 Tablet with food to reduce stomach discomfort.
Dizziness: Consider taking this medicine at night to manage this effect.

Clopivas AP 150 Tablet contains two active ingredients:

Aspirin (150 mg): Aspirin acts by irreversibly inactivating enzymes called cyclooxygenases (COX), which are involved in the production of substances known as prostaglandins and thromboxanes. These substances cause platelets in your blood to clump together, a process known as aggregation. By inhibiting their production, aspirin effectively reduces platelet aggregation.
Clopidogrel (75 mg): This is classified as a prodrug, meaning it needs to be activated by certain enzymes in your body (predominantly CYP2C19) before it takes effect. After activation, clopidogrel forms a metabolite that prevents a substance called ADP from binding to its receptor found on platelets. This action helps inhibit platelet aggregation, reducing the likelihood of clot formation.

Pregnancy

Clopivas AP 150 Tablet may cause harm to the unborn baby, especially in the third trimester. If you're pregnant or planning to conceive, it's best to consult your doctor prior to taking this medicine.

Breastfeeding

Breastfeeding while taking Clopivas AP 150 Tablet is generally not advised. It's recommended to discuss with your doctor to understand potential risks and benefits.

Alcohol

While taking Clopivas AP 150 Tablet, you're advised to limit alcohol consumption. Alcohol can increase the risk of stomach bleeding.

Liver

If you have liver issues, particularly severe liver impairment, caution is advised before starting Clopivas AP 150 Tablet. Discuss this with your doctor who can assess if this medicine is suitable for you.

Kidney

People with kidney conditions should exercise caution before using Clopivas AP 150 Tablet. It's advisable to consult your doctor if you have any history of kidney issues.

Using Machines & Driving

Clopivas AP 150 Tablet may cause dizziness. If affected, avoid driving or operating machinery until you feel well again.

Allergy

If you are allergic to aspirin, clopidogrel or any other components of Clopivas AP 150 Tablet, avoid taking this medicine.

Children

This medicine isn't typically given to children under 18 years of age. Always consult your doctor before giving any medication to a child.

Older Patients

Older patients should take Clopivas AP 150 Tablet under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Interactions of Clopivas Ap 150 Tablet 15

Drug-Drug Interactions

Clopivas AP 150 Tablet interacts with the following medicines:

Anticoagulants: Medicines like warfarin and heparin may interact with Clopivas AP 150 Tablet, potentially increasing the risk of bleeding.
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): When taken with this tablet, NSAIDs such as ibuprofen and naproxen can increase the risk of gastrointestinal bleeding and reduce the antiplatelet efficacy of aspirin.
Antidepressants: Medicines like fluoxetine and venlafaxine can potentially increase your risk of bleeding when taken with Clopivas AP 150 Tablet.
Antacids: Medicines like omeprazole and esomeprazole can reduce the antiplatelet efficacy of clopidogrel when used concomitantly with this tablet.

Drug-Food Interactions

There are no specific known food interactions with Clopivas AP 150 Tablet.

Drug-Disease Interactions

Clopivas AP 150 Tablet interacts with the following diseases:

Gastrointestinal bleeding or ulcer: If you have a history of these conditions, you might experience an increased risk of bleeding when using this medicine.
Bleeding disorders: Patients suffering from any bleeding disorders need to be cautious, as it may exacerbate the condition.
Severe liver or kidney impairment: The use of Clopivas AP 150 Tablet in patients with severe liver or kidney disease could lead to increased medicine levels in the body.

Daily Dose

The daily dose of Clopivas AP 150 Tablet should be as advised by your doctor. Your dosage could vary based on your health condition and how well you respond to the medicine. Sticking to the prescribed dosage and not exceeding it without consulting your doctor is crucial.

Over Dose

Taking more than the recommended dose of Clopivas AP 150 Tablet may lead to common side effects such as nausea, vomiting, or abdominal pain. If you experience discomfort after taking this medication, you should inform your doctor.

Missed Dose

If you forget to take your Clopivas AP 150 Tablet, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your normal schedule. Never increase your dosage without consulting your doctor.

Store Clopivas AP 150 Tablet at room temperature.
Keep this medicine in a dry place, away from direct sunlight and moisture.
Always keep the tablet out of reach of children.
Ensure to use the medicine before its expiry date.

If you're taking Clopivas AP 150 Tablet, try to eat a balanced diet that's low in saturated fats and cholesterol. This can help reduce your risk of heart disease and stroke, which this medicine helps manage.
Limit alcohol intake. Alcohol can increase the risk of bleeding, a potential side effect of Clopivas AP 150 Tablet.

Fact Box

Drug Category	Antiplatelet Agents
Therapeutic Category	Cardiovascular Medication
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Heart attacks, Strokes, Acute coronary syndrome

What is Clopivas AP 150 Tablet used for?

It is useful in preventing heart attacks, strokes, and managing acute coronary syndrome amongst high-risk individuals.

How does Clopivas AP 150 Tablet work?

It comprises aspirin and clopidogrel that reduce platelet aggregation, hence decreasing the chances of blood clot formation.

How should I take Clopivas AP 150 Tablet?

Take the tablet daily, orally, with or without food. Swallow it whole, without crushing, chewing, or breaking it.

What are the common side effects of Clopivas AP 150 Tablet?

Common side effects may include gastrointestinal disturbances, bleeding, bruising, dizziness, and headache.

Can I take Clopivas AP 150 Tablet if I am pregnant or breastfeeding?

Its use during pregnancy or breastfeeding may not be safe. Please consult your doctor before taking it.

Are there any precautions to be taken while using Clopivas AP 150 Tablet?

Yes, inform your doctor about its usage before any surgical procedures and avoid if you have a history of severe bleeding disorders.

Can I consume alcohol while taking Clopivas AP 150 Tablet?

Avoid consuming alcohol while on this medication and consult your doctor regarding dietary restrictions.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: INDIA

References

Unknown. (n.d.). Summary of Product Characteristics (Product Data Sheet) (pp. 81–83). https://rwandafda.gov.rw/wp-content/uploads/2023/03/Instaclop-Plus-Clopidogrel-75-mg-and-Aspirin-75-mg-Capsules-SmPC.pdf
Clopidogrel: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00758
Aspirin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00945
Payne, D. A., Hayes, P. D., Jones, C. I., Belham, P., Naylor, A. R., & Goodall, A. H. (2002). Combined therapy with clopidogrel and aspirin significantly increases the bleeding time through a synergistic antiplatelet action. Journal of Vascular Surgery, 35(6), 1204–1209. https://doi.org/10.1067/mva.2002.122027

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