Cobex 03 Eye Drop 10 Ml

Cobex 0.3 % Eye Drop 10 ML

Biocare Remedies

Pack of 10 ML

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MRP ~~₹25~~

₹20.5

₹2.50/ML

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Prescription required for this medicine

Store Below 30^o C

Composition

Tobramycin (0.3 %)

Cobex 0.3 % Eye Drop 10 ML are primarily used for managing bacterial infections of the eye. This medication is part of the aminoglycoside antibiotics class.

Besides its main use, this medicine is also beneficial in tackling various other infections caused by bacteria susceptible to tobramycin, the active ingredient of this medicine. The spectrum of bacteria includes Staphylococci, Streptococci, Pseudomonas aeruginosa, Escherichia coli, and several others.

Before you start using this medicine, consult your doctor for the appropriate dosage and frequency. It's important to notify your doctor about any pre-existing health conditions or ongoing medications to avoid harmful interactions. If you experience any side effects while using this medicine, inform your doctor immediately. For optimal results, continue taking this medicine for the duration prescribed by your doctor.

Cobex 0.3 % Eye Drop 10 ML are used to manage various bacterial eye infections caused by Staphylococcus, Streptococci, Pseudomonas aeruginosa, Escherichia coli, Morganella morganii, Proteus vulgaris strain-related conditions, Haemophilus influenzae, and H. aegyptius.

Directions for Use of Cobex 0.3 % Eye Drop 10 ML

Wash your hands thoroughly.
Tilt your head back slightly and pull down your lower eyelid to create a small pouch.
Squeeze the bottle gently to the prescribed amount into the eye pouch, ensuring the Dropsper tip does not touch any surface.
Close your eyes and press your finger on the inside corner of your eye for about 1-2 minutes.
If you are also using other eye drops, wait for at least a few minutes before instilling the next one.

Cobex 0.3 % Eye Drop 10 ML is instilled topically.

Side Effects of Cobex 0.3 % Eye Drop 10 ML

Cobex 0.3 % Eye Drop 10 ML may have the following common side effects:

Hypersensitivity reactions
Localised ocular toxicity: This might cause itching of the eyelid, swelling of the eyelid, or redness in the white part of your eye.
Burning, stinging or discomfort upon instillation
Anaphylactic reaction: This is a severe allergic reaction that can cause trouble breathing, dizziness, or rash. If this happens, seek immediate medical help.
Stevens-Johnson syndrome and erythema multiforme: These are serious skin conditions that may cause red, painful rashes that can lead to peeling skin.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolves on discontinuing the use of Cobex 0.3 % Eye Drop 10 ML. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

If you face any discomfort:

Burning or stinging sensation: Try waiting for a few minutes before you open your eyes after instilling Cobex 0.3 % Eye Drop 10 ML.
Discomfort upon instillation: If you feel uncomfortable after instilling the eye drops, try closing your eyes for a couple of minutes to let it settle.

Cobex 0.3 % Eye Drop 10 ML contain Tobramycin (0.3%), which works on your body in the following ways:

Inhibits Bacterial Protein Synthesis: Tobramycin blocks the process that bacteria use to create proteins essential for their growth and reproduction.
Alters Cell Membrane Permeability: By interfering with protein synthesis, Tobramycin weakens the bacterial cell membrane, making it more permeable.
Leads to Cell Death: As a result of altered cell membrane permeability and disruption of the cell envelope, the bacterial cells eventually die, thereby reducing the bacterial infection in your eyes.

Pregnancy

If you're expecting, caution is advised while using Cobex 0.3 % Eye Drop 10 ML. It's best to consult your doctor before you start this medication.

Breastfeeding

Nursing mothers should exercise caution when using Cobex 0.3 % Eye Drop 10 ML, as it's unknown whether tobramycin is excreted in human milk following topical ophthalmic instillation. It would be wise to consult your doctor before using this medicine.

Alcohol

Interactions between alcohol and Cobex 0.3 % Eye Drop 10 ML are rare, given that it's a topical product. However, you should always consult your doctor if you have any doubts.

Liver

For those with liver health concerns, there are rarely any precautions required with topical products like Cobex 0.3 % Eye Drop 10 ML but do check with your doctor if you're unsure.

Kidney

As with liver health concerns, kidney issues are rarely relevant for topical products like Cobex 0.3 % Eye Drop 10 ML, but it's always wise to speak with your doctor if in doubt.

Using Machines & Driving

If you experience any discomfort or visual disturbance after application, avoid such activities until your vision clears.

Allergy

Cobex 0.3 % Eye Drop 10 ML should not be used if you're allergic to tobramycin or any other component of the formulation. If a hypersensitivity reaction occurs, discontinue use immediately.

Children

Caution is advised when giving this medicine to children. Always consult your doctor before giving any medication to a child.

Older Patients

No significant differences in safety or effectiveness have been observed between elderly and younger adult patients using Cobex 0.3 % Eye Drop 10 ML. However, if you're an older patient, it's always good practice to consult your doctor before starting any new medication.

Interactions of Cobex 0.3 % Eye Drop 10 ML

Drug-Drug Interactions

Cobex 0.3 % Eye Drop 10 ML interacts with the following medicines:

Other Ophthalmic Medications: If you are using other eye drops or ointments, ensure a gap of 5-10 minutes between each medication to avoid dilution or washout of Cobex 0.3 % Eye Drop 10 ML.
Loop Diuretics: Furosemide (Lasix) or other loop diuretics can enhance the ototoxic potential of tobramycin. Combining these medications may lead to an increased risk of hearing damage, especially when high doses are used, or the duration of therapy is prolonged.

Drug-Food Interactions

None

Drug-Disease Interactions

Cobex 0.3 % Eye Drop 10 ML interact with the following diseases:

Hypersensitivity: If you have ever had an allergic reaction to tobramycin or any other component of Cobex 0.3 % Eye Drop 10 ML, you should avoid using this medicine as it could cause severe allergic reactions.
Fungal Infections: Prolonged use of Cobex 0.3 % Eye Drop 10 ML may lead to the overgrowth of non-susceptible organisms, including fungi. If you have a history of fungal eye infections, use this medicine with caution.

Daily Dose

The recommended dosage of Cobex 0.3 % Eye Drop 10 ML should be used as guided by your doctor. This might differ based on the severity of your condition and how you react to the medicine. It's crucial to adhere to the prescribed dosage and not exceed it without a doctor's consultation.

Over Dose

In case you accidentally instil more drops than instructed, do not panic. Cleanse your eyes with water at room temperature. If any discomfort persists or worsens, inform your doctor.

Missed Dose

If you forget to instil Cobex 0.3 % Eye Drop 10 ML at the scheduled time, do so as soon as you remember. But if it's nearly time for your next dose, skip the missed one and continue with your normal schedule. Never increase your dosage without consulting your doctor.

Store Cobex 0.3 % Eye Drop 10 ML at room temperature.
Keep away from excessive heat and direct sunlight.
Ensure the container is always tightly sealed to prevent air exposure.
Keep well out of reach of children.

Maintain good eye hygiene. Regularly clean your eyes with a clean, soft cloth to keep them free from dust and debris that could cause infections.
Avoid wearing contact lenses when you have symptoms of an eye infection. This can exacerbate the condition by trapping bacteria against your eye.

Fact Box

Drug Category	Protein Synthesis Inhibitor
Therapeutic Category	Antibiotic
Available Dosage Types	Eye Drops
Habit Forming	No
Ailment	External Bacterial Eye Infections

What are Cobex 0.3 % Eye Drop 10 ML used for?

Cobex 0.3 % Eye Drop 10 ML are used to manage external bacterial eye infections caused by bacteria susceptible to tobramycin.

How does Cobex 0.3 % Eye Drop 10 ML work?

The active ingredient, tobramycin, inhibits bacterial protein synthesis, altering cell membrane permeability and leading to cell death.

Can I wear contact lenses while using Cobex 0.3 % Eye Drop 10 ML?

No, it's recommended not to wear contact lenses if you have signs of a bacterial eye infection.

What should I do if I experience an allergic reaction after using Cobex 0.3 % Eye Drop 10 ML?

Discontinue the medicine and consult your doctor immediately if you experience any allergic reactions.

Can I use other eye Drops along with Cobex 0.3 % Eye Drop 10 ML?

Yes, but wait for 5-10 minutes between instilling different types of eye drops to avoid dilution or washout.

Why should I continue using the medicine even after my symptoms improve?

Abruptly stopping the medication may lead to a relapse of the infection. Always complete the course prescribed by your doctor.

How should I store Cobex 0.3 % Eye Drop 10 ML?

Store the drops at room temperature, protect them from excessive heat and keep the bottle tightly closed.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

24,Industrial Area ,Ambala Cantt. , Haryana State (India)

References

Tobramycin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00684
Tobramycin ophthalmic: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a682660.html
DailyMed - TOBRAMYCIN OPHTHALMIC SOLUTION solution/ drops. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3c23234a-452b-40d0-922f-37e49147d537
PubChem. (n.d.). Tobramycin. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/36294
Reyhanoglu, G., & Reddivari, A. K. R. (2023, August 12). Tobramycin. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK551695/

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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