Cobix 200 Mg Capsule 10

Cobix 200 Capsule 10

Cipla Ltd.

Strip of 10 Units

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MRP ~~₹140.80~~

₹70.26

₹14.08/Units

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Composition

Celecoxib (200 Mg)

Strength:

200 MG 100 MG

Cobix-200 Capsule is often used to manage pain, inflammation, and stiffness associated with certain conditions in adults. This medicine is a type of NSAID, more specifically a COX-2 selective inhibitor.

In addition to its primary use, this medicine also helps to relieve symptoms related to osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and menstrual cramps. It is particularly beneficial in managing acute pain in adults and treating primary dysmenorrhoea.

Before starting this medicine, it is important that you consult your doctor who will determine the correct dosage and frequency based on your condition. Inform your doctor about any pre-existing conditions or ongoing medications. If you experience any side effects while taking this medicine, notify your doctor immediately. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

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Cobix-200 Capsule is used for the following:

Managing pain, inflammation, and stiffness in Osteoarthritis
Controlling signs and symptoms of Rheumatoid Arthritis
Helping adults manage Acute Pain
Easing the discomfort of Primary Dysmenorrhea, also known as menstrual cramps

Directions for Use of Cobix 200 Capsule 10

Here's how you should take your Cobix-200 Capsule:

Swallow the capsule whole with a glass of water. Avoid crushing or chewing it.
Remember, if you miss a dose, take it as soon as you remember. But never take two doses together to make up for a missed one. Always consult your doctor for more specific advice on how to use this medicine.

Cobix-200 Capsule is taken orally.

Cobix-200 Capsule may have the following common side effects:

Dyspepsia: This is a fancy term for indigestion, which might cause bloating or discomfort in your tummy.
Diarrhoea
Abdominal pain
Flatulence: This simply means passing wind or gas.
Peripheral oedema: This refers to swelling in your hands and feet caused by fluid build-up.
Rash

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Cobix-200 Capsule. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Dyspepsia: If you have indigestion, take Cobix-200 Capsule after meals to lessen this effect.
Diarrhoea: Ensure you stay hydrated by drinking plenty of fluids.

Cobix-200 Capsule contains celecoxib (200 mg). Here's how it works:

Selective COX-2 Inhibition: Celecoxib functions by selectively inhibiting an enzyme known as cyclooxygenase-2 (COX-2). This enzyme is responsible for producing prostaglandins, substances in your body that cause inflammation, pain, and fever. By blocking COX-2, celecoxib effectively reduces these symptoms.
Gastric Protection: Unlike some other NSAIDs, celecoxib doesn't significantly inhibit another enzyme called COX-1. This enzyme helps protect the lining of your stomach. Therefore, the risk of causing gastric ulcers is lower with celecoxib compared to non-selective NSAIDs.

Pregnancy

Expecting mothers should use Cobix-200 Capsule with caution, particularly after 30 weeks of gestation, as it could impact the baby's health. Always consult your doctor before taking this medicine while pregnant.

Breastfeeding

Cobix-200 Capsule is known to pass into breast milk. It is advised to stop nursing or discontinue the medicine, considering its importance to you. Always discuss this with your doctor first.

Alcohol

It's always wise to limit alcohol consumption while on any medication, and consult your doctor if in doubt.

Liver

If you have liver problems, caution is recommended when taking Cobix-200 Capsule. This medicine could affect liver function. Make sure to discuss this with your doctor before starting this medicine.

Kidney

Cobix-200 Capsule should be used cautiously in patients with advanced kidney disease. Regular monitoring of kidney function might be necessary if you have kidney issues.

Using Machines & Driving

It's not clear whether Cobix-200 Capsule can impact your ability to drive or operate machinery. If you feel dizzy or unwell after taking the medicine, avoid such activities and consult your doctor.

Allergy

Avoid Cobix-200 Capsule if you're allergic to celecoxib or other components of the capsule, or have shown allergic reactions to sulfonamides.

Children

Safety and effectiveness of Cobix-200 Capsule in children haven't been established yet. It's best not to give this medicine to children without consulting a doctor.

Older Patients

Older patients are advised to use Cobix-200 Capsule under medical supervision due to their greater likelihood of having decreased liver, kidney or cardiac function. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Cobix-200 Capsule interacts with the following medicines:

Anticoagulants: Medicines such as warfarin can interact with Cobix-200 Capsule, potentially leading to serious bleeding complications.
Antihypertensives: When taken with Cobix-200 Capsule, medicines like lisinopril and losartan may reduce their blood pressure-lowering effect.
Diuretics: Diuretic medicines like furosemide may have a decreased natriuretic effect when taken with Cobix-200 Capsule, increasing the risk of kidney failure.

Drug-Food Interactions

There are no known specific food interactions with Cobix-200 Capsule.

Drug-Disease Interactions

Cobix-200 Capsule interacts with the following diseases:

Cardiovascular Disease: Cobix-200 Capsule may increase the risk of serious cardiovascular events like heart attacks and strokes, especially in patients with pre-existing cardiovascular disease.
Gastrointestinal Disorders: Patients with active gastrointestinal bleeding or ulcers should use caution as Cobix-200 Capsule could exacerbate their condition.
Advanced Renal Disease: Cobix-200 Capsule should be used cautiously in patients with advanced renal disease due to potential worsening of kidney function.

Daily Dose

The daily dose of Cobix-200 Capsule should be taken as directed by your doctor. The dosage may vary based on individual factors like the severity of your condition and how you respond to the medicine. Always adhere to the prescribed dosage and never exceed it without consulting your doctor.

Over Dose

If you accidentally take more than the recommended dose of Cobix-200 Capsule, you might feel drowsy or nauseous. In such a case, rinse your mouth with water and rest. If these symptoms persist or worsen, please inform your doctor.

Missed Dose

If you forget to take Cobix-200 Capsule at the scheduled time, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and carry on with your regular schedule. Remember, never alter your dosage without consulting your doctor.

Store Cobix-200 Capsule at room temperature.
Keep it away from excessive moisture; a dry place is best.
Always keep this medicine out of the reach of children.
Always check the expiry date before use and avoid using any past their expiry date.

If you're managing osteoarthritis or rheumatoid arthritis with Cobix-200 Capsule, try to maintain a balanced diet rich in omega-3 fatty acids (like fish, flaxseeds), which can help reduce inflammation.
Regular low-impact exercise like swimming or cycling can help improve joint flexibility and reduce stiffness. However, always consult your doctor before starting any new exercise regime.

Fact Box

Drug Category	COX-2 Selective Inhibitor
Therapeutic Category	Nonsteroidal Anti-Inflammatory
Available Dosage Types	Capsule
Habit Forming	No
Ailment	Osteoarthritis, Rheumatoid Arthritis, Primary Dysmenorrhea

Can I take Cobix-200 Capsule if I have an allergy to sulfa medications?

No, you should avoid Cobix-200 Capsule if you've had allergic reactions to sulfonamides.

Can Cobix-200 Capsule be taken long-term for conditions like osteoarthritis?

Yes, under medical supervision, Cobix-200 Capsule can be used for chronic conditions like osteoarthritis.

What should I do if I miss a dose of Cobix-200 Capsule?

If you miss a dose, take it as soon as you remember. Don't take extra medicine to compensate for the missed one.

Is it safe to take Cobix-200 Capsule if I've had stomach ulcers before?

Celecoxib can increase the risk of gastric bleeding, so discuss with your doctor if the benefits outweigh the risks.

Is Cobix-200 Capsule safe to use during pregnancy?

It's advisable to avoid using Cobix-200 Capsule after 30 weeks of pregnancy due to potential risks for the fetus.

Can I breastfeed while taking Cobix-200 Capsule?

Celecoxib is excreted in breast milk; therefore, discontinue nursing or the medicine after consulting your doctor.

Is it safe for children to use Cobix-200 Capsule?

The safety and effectiveness of Cobix-200 Capsule in paediatric patients have not been established yet. Always consult your doctor.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: INDIA

References

Pfizer. (1998). HIGHLIGHTS OF PRESCRIBING INFORMATION [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/020998s050lbl.pdf
Pfizer. (2008). HIGHLIGHTS OF PRESCRIBING INFORMATION. https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/020998s027lbl.pdf
Cohen, B., & Preuss, C. V. (2024, February 28). Celecoxib. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK535359/
Celecoxib: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00482
Celecoxib: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a699022.html

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