Concor Plus 5125 Mg Tablet 10

Concor Plus Tablet 10

Merck Ltd

Strip of 10 Units

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Composition

Bisoprolol (5 Mg) + Hydrochlorothiazide (12.5 Mg)

Concor Plus Tablet is primarily used to manage hypertension (high blood pressure). This is a combination medicine that falls under the category of antihypertensives.

In addition to hypertension management, it also aids in the prevention of severe cardiovascular events such as heart attacks and strokes. Particularly beneficial when a single medicine isn't effective, it helps in achieving better control over blood pressure levels.

Before you start taking this medicine, consult your doctor about your medical history and any ongoing medications. If you notice any side effects, notify your doctor immediately. It's crucial to continue taking the medicine for the duration prescribed by your doctor for the most beneficial results.

Concor Plus Tablet is used for managing the following health conditions:

Control of high blood pressure
Prevention of major cardiovascular events, such as heart attacks and strokes
Protection of the kidneys in high-risk patients with hypertension

Directions for Use of Concor Plus Tablet 10

To correctly use Concor Plus Tablet, consider these steps:

Follow the instructions, dosage and timings prescribed by your doctor thoroughly.
Do not change the dosage on your own.
Maintain the diet recommended, and do not engage in activities forbidden by your doctor.

Concor Plus Tablet is taken orally.

Concor Plus Tablet may have the following common side effects:

Fatigue
Dizziness
Headache
Nausea
Constipation
Diarrhoea
Cold extremities: This can be experienced as cold hands or feet.
Slow heart rate: Also known as bradycardia, this is when your heart beats slower than normal.
Increased blood uric acid levels: This can sometimes lead to conditions like gout.
Altered blood lipid levels: This can affect the amount of fats, such as cholesterol and triglycerides, in your blood.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Concor Plus Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some guidelines to manage a couple of common side effects:

Nausea: Follow the diet and timings prescribed by your doctor. If the problem persists, inform your doctor.
Constipation: If you have this problem for a significant amount of time after taking the medicine, seek advice from your doctor.

Concor Plus Tablet consists of two active components:

Bisoprolol (5 mg): As a selective beta-1 adrenergic receptor blocker, Bisoprolol acts on your heart. It reduces both your heart rate and the force of your heart contractions, lowering your heart's workload and oxygen demand. By enhancing the efficiency of your heart's pumping action, Bisoprolol aids in reducing blood pressure.
Hydrochlorothiazide (12.5 mg): This thiazide diuretic contributes to lowering blood pressure by increasing urine production, which helps remove excess water and salt from your body. Over time, it also relaxes and widens your blood vessels, enhancing blood flow and contributing further to managing high blood pressure.

The combined activity of these two medicines results in a more significant reduction in blood pressure than either component alone.

Pregnancy

Concor Plus Tablet is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Concor Plus Tablet is contraindicated for breastfeeding/lactating women. Consult your doctor to understand the potential risks and benefits.

Alcohol

It's best to avoid alcohol consumption while taking Concor Plus Tablet, as it may increase the risk of side effects such as dizziness and low blood pressure.

Liver

Caution is advised while taking Concor Plus Tablet in case of mild to moderate liver impairment. It is not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting Concor Plus Tablet. This medicine may affect liver function.

Kidney

Caution is advised before using Concor Plus Tablet if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

Concor Plus Tablet may cause dizziness, especially when starting treatment or increasing the dose. You should exercise caution when driving or operating machinery.

Allergy

This medicine is contraindicated in patients with hypersensitivity to Bisoprolol, Hydrochlorothiazide, or any of the excipients in Concor Plus Tablet.

Children

Caution is advised while giving Concor Plus Tablet to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Concor Plus Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Older patients might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Concor Plus Tablet interacts with the following medicines:

Antihypertensive Medicines: Concor Plus Tablet, when taken alongside other blood pressure-lowering medications like amlodipine or lisinopril, may increase the risk of low blood pressure.
Anti-diabetic Medicines: The tablet's action can affect blood sugar levels which may interfere with the effectiveness of diabetes medications like insulin or metformin.
NSAIDs: Medicines such as ibuprofen or naproxen can reduce the effectiveness of Concor Plus Tablet in managing blood pressure.
Heart Medications: Certain heart medicines like digoxin may interact with Concor Plus Tablet, leading to increased levels of digoxin in the body.

Drug-Food Interactions

There are no interactions between Concor Plus Tablet and any specific food item.

Drug-Disease Interactions

Concor Plus Tablet interacts with the following diseases:

Diabetes: This medicine could affect blood sugar control, so sugar levels need to be monitored closely.
Liver Disease: Patients with liver disease should exercise caution as this medicine could potentially worsen their condition.
Kidney Disease: Caution is advised as Concor Plus Tablet could lead to electrolyte imbalance in patients with kidney disease.

Daily Dose

The daily dosage of Concor Plus Tablet must be strictly as advised by your doctor. The dosage may vary depending on individual factors, such as the severity of your condition and how you respond to the medicine. Always stick to the prescribed dosage, and never change it without consulting your doctor.

Over Dose

Taking more than the prescribed dose of Concor Plus Tablet may lead to overdose symptoms such as dizziness, fatigue, and slow heart rate. If you suspect that you have taken an overdose, inform your doctor immediately.

Missed Dose

If you happen to miss a dose of Concor Plus Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular dosing schedule. Never take extra medicine to make up for a missed dose. Always consult your doctor if unsure about what to do after missing a dose.

Store Concor Plus Tablet at room temperature, ideally between 15-30°C.
Keep it in a dry place, shielded from light and moisture.
Ensure the storage area is out of reach of children.
Always use this medicine before the expiry date indicated on the packaging.

Cut down on your salt intake, as a high salt diet can increase blood pressure, counteracting the benefits of Concor Plus Tablet.
Regular physical activity such as walking or cycling can help lower your blood pressure. However, consult your doctor before starting any new exercise regimen.

Fact Box

Drug Category	Beta-1 Blocker, Diuretic
Therapeutic Category	Antihypertensive
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypertension, Cardiovascular Prevention

What is Concor Plus Tablet used for?

Concor Plus Tablet is used to manage high blood pressure in cases where one medicine alone isn't effective enough.

How does Concor Plus Tablet work?

The tablet contains two active ingredients, bisoprolol and hydrochlorothiazide, which work together to lower blood pressure and reduce the heart's workload.

Can I take this medication during pregnancy or breastfeeding?

It's not recommended to take Concor Plus Tablet during pregnancy or breastfeeding. Always consult your doctor for alternative options.

What should I do if I forget to take a dose of Concor Plus Tablet?

If you miss a dose, take it as soon as you remember. If it's nearly time for the next dose, skip the missed one.

Can I stop taking Concor Plus Tablet if I feel better?

Stopping Concor Plus Tablet suddenly can lead to rebound hypertension. Always consult your doctor before discontinuing any medication.

Are there any side effects of taking Concor Plus Tablet?

Some people may experience side effects like fatigue, dizziness, headache, nausea, and changes in blood mineral levels.

Can I consume alcohol while taking this medicine?

It's best to avoid alcohol while on Concor Plus Tablet as it might increase the risk of dizziness and low blood pressure.

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 5 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 10 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

Godrej One, 8th floor, Pirojsha Nagar,, Eastern Express Highway,, Vikroli East, Mumbai, Maharashtra 400079

Country of origin: INDIA

References

MedlinePlus. (n.d.). Bisoprolol. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a693024.html
MedlinePlus. (n.d.). Hydrochlorothiazide. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a682571.html
U.S. Food and Drug Administration. (2011). ZIAC (bisoprolol fumarate and hydrochlorothiazide) Tablets. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/019982s016lbl.pdf
Unknown. (n.d.). ZEBETA (BISOPROLOL FUMARATE) TABLETS - bisoprolol fumarate tablet (p. page 1 of 8). https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/019982s014lbl.pdf
Hydrochlorothiazide: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00999
Bisoprolol: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00612

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