Cortis 40 Injection 1

Cortis 40 Injection 1 is used for managing various health conditions, including:

• Arthritis and other joint disorders to control pain and swelling

• Severe allergic reactions such as anaphylaxis or angioedema

• Specific blood disorders, cancers, and immune system diseases

• Endocrine disorders like congenital adrenal hyperplasia

• Cerebral oedema related to brain tumours or head injury

• Sudden worsening of multiple sclerosis symptoms

• Skin conditions including pemphigus and erythema multiforme

• Inflammatory eye problems like optic neuritis

• Respiratory issues such as aspiration pneumonitis and asthma

• Gastrointestinal diseases including ulcerative colitis or regional enteritis.

To administer Cortis 40 Injection 1 correctly, follow these steps:

• Shake the vial well before use.

• The injection should only be administered by a qualified healthcare professional.

• It can be administered into a muscle (intramuscular), directly into a joint (intra-articular), into soft tissue, or into skin lesions (intralesional), depending on the condition being managed.

• Remember, this injection is not meant for intravenous use.

• For specific advice on how frequently you should have this injection and the correct dose for your condition, always consult your doctor.

Cortis 40 Injection 1 can be administered into a muscle (intramuscular), directly into a joint (intra-articular), into soft tissue, or into skin lesions (intralesional).

Cortis 40 Injection 1 contains methylprednisolone (40 mg), which exerts its effects on the body as follows:

• Glucocorticoid Receptor Binding: Methylprednisolone binds to receptors in the cytoplasm. These are called glucocorticoid receptors. By binding to these receptors, it triggers a process that reduces inflammation.

• Gene Transcription Activation: Once bound to its receptor, methylprednisolone activates genes that help fight inflammation. This means it turns on certain genes that help reduce swelling and redness.

• Repression of Pro-Inflammatory Genes: At the same time, it turns off or "represses" genes that cause inflammation. This further helps in managing inflammation.

• Mineralocorticoid Activity: Methylprednisolone has some activity similar to mineralocorticoids - hormones that help maintain sodium levels in your body. This can lead to sodium retention in the body, which can affect fluid balance.

• Keep Cortis 40 Injection 1 at room temperature.

• Protect it from sun light; hence, store it in a dark place.

• Do not refrigerate or freeze this medicine.

• Keep it out of reach of children to prevent accidental intake.

• If you are managing arthritis with Cortis 40 Injection 1, consider a diet rich in omega-3 fatty acids such as fish and walnuts; they may help reduce inflammation.

• For those using Cortis 40 Injection 1 for respiratory conditions like asthma, try to stay away from allergens such as smoke, dust mites, or pollen which could trigger an asthma attack.