Dabigatrex 150 Capsule 10

Steris Healthcare

Strip of 10 Units

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Composition

Dabigatran Etexilate (150 Mg)

Strength:

150 MG 75 MG 110 MG

Dabigatrex 150 Capsule 10 is primarily used to minimise the risk of stroke and systemic embolism in people with non-valvular atrial fibrillation. This medicine belongs to a class of medications known as anticoagulants.

It is used to manage and prevent deep vein thrombosis (DVT) and pulmonary embolism (PE). It aids in preventing the recurrence of these conditions in adults and is also effective in managing blood clots in children.

You must take this medication as instructed by your doctor. Before starting on this medicine, inform your doctor about any preexisting health conditions or ongoing medications. If you experience any severe side effects, notify your doctor immediately. To achieve the best results, it’s essential to continue taking the medicine for the duration prescribed by your doctor.

Dabigatrex 150 Capsule 10 is used for the following conditions:

Non-valvular atrial fibrillation
Deep vein thrombosis (DVT)
Pulmonary embolism (PE)

Directions for Use of Dabigatrex 150 Capsule 10

Here's how you should take Dabigatrex 150 Capsule 10:

Swallow the capsule whole with a glass of water. Avoid chewing or crushing it.
Take this medicine as advised by your doctor. Do not alter the dose or stop taking it without medical guidance.
Consult your doctor for specific advice related to your health condition.

Dabigatrex 150 Capsule 10 is taken orally.

Side Effects of Dabigatrex 150 Capsule 10

Dabigatrex 150 Capsule 10 may lead to a few side effects, which include:

Stomach pain
Diarrhoea
Nausea
Increased risk of bleeding or bruising: This medicine can sometimes cause you to bleed or bruise more easily than usual.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Dabigatrex 150 Capsule 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are a couple of tips to manage common side effects:

Stomach pain: You might find it helpful to take Dabigatrex 150 Capsule 10 with a meal or snack.
Diarrhoea: Try taking your dose at night if it leads to frequent loose bowel movements during the day.

Dabigatrex 150 Capsule 10 contains Dabigatran Etexilate (150 mg), which acts on your body as follows:

Direct thrombin inhibition: Dabigatran etexilate blocks an enzyme called thrombin in your body. Thrombin plays a crucial role in blood clot formation.
Prevention of clot formation: By blocking the activity of thrombin, dabigatran etexilate prevents the conversion of fibrinogen to fibrin, thereby reducing the formation of blood clots. This action makes your blood less likely to clot, decreasing the risk of serious cardiovascular events.

Pregnancy

Caution is advised while taking Dabigatrex 150 Capsule 10 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Dabigatrex 150 Capsule 10 is not recommended for breastfeeding women. Discuss with your doctor to understand the potential risks and benefits before starting this medicine.

Alcohol

Avoid consuming alcohol while taking Dabigatrex 150 Capsule 10, as it may increase the risk of bleeding.

Liver

If you have liver problems, discuss them with your doctor before starting the Dabigatrex 150 Capsule 10. This medicine may affect liver function, especially in severe cases.

Kidney

Caution is advised before using Dabigatrex 150 Capsule 10 if you have a history of any kidney problems. Consult your doctor to understand the potential risks and benefits.

Using Machines & Driving

No specific information is available about whether the Dabigatrex 150 Capsule 10 affects your ability to drive or operate machinery. However, as with all medications, ensure you know how it affects you before driving or using machines.

Allergy

If you have a known allergy to Dabigatran Etexilate or any other ingredients present in Dabigatrex 150 Capsule 10, avoid using this medicine.

Children

Dabigatrex 150 Capsule 10 should be given with caution to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Dabigatrex 150 Capsule 10 under medical supervision, as they may be more susceptible to its side effects. They might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Interactions of Dabigatrex 150 Capsule 10

Drug-Drug Interactions

Dabigatrex 150 Capsule 10 interacts with the following medicines:

Anticoagulants: Other anticoagulant medicines like warfarin and heparin can increase the risk of bleeding when taken with this capsule.
NSAIDs: Non-steroidal anti-inflammatory drugs such as ibuprofen and naproxen can also heighten the risk of bleeding when taken alongside this medicine.
Anti-platelet drugs: Medicines like aspirin and clopidogrel may further enhance the chance of bleeding when combined with this capsule.
P-glycoprotein inducers: Medications like rifampicin can reduce the effectiveness of Dabigatrex 150 Capsule 10 due to increased metabolism.
P-glycoprotein inhibitors: Certain medicines such as ketoconazole and dronedarone can increase exposure to dabigatran, thereby increasing its anticoagulant effects.

Drug-Food Interactions

There are no known significant food interactions with Dabigatrex 150 Capsule 10.

Drug-Disease Interactions

Dabigatrex 150 Capsule 10 interacts with the following diseases:

Bleeding disorders: Active bleeding disorders may be exacerbated by this medication due to its anticoagulant properties.
Stomach ulcers: The risk of serious bleeding is elevated in patients with stomach ulcers who take this medicine.
Severe kidney or liver dysfunction: Patients with severe kidney or liver disease may experience a heightened risk of bleeding due to reduced excretion of dabigatran.

Daily Dose

The daily dose of Dabigatrex 150 Capsule 10 is taken as directed by your doctor. This dosage could vary based on factors like your current health condition and how your body responds to the medicine. Always follow the prescribed dosage and never change it without consulting your doctor.

Over Dose

If you happen to take more than the prescribed dose of Dabigatrex 150 Capsule 10, you may experience side effects such as stomach pain, diarrhoea, or nausea. If these symptoms persist or worsen, please inform your doctor.

Missed Dose

If you forget to take your regular dose of Dabigatrex 150 Capsule 10, take it as soon as you remember. However, if it's nearing time for your next dose, skip the missed one and continue with your usual dosage schedule. Never increase your dosage without consulting your doctor.

Store Dabigatrex 150 Capsule 10 at room temperature, specifically between 20 °C and 25 °C.
Protect it from direct sunlight, heat, and moisture.
Keep this medicine in its original packaging until it's time to take it.
Always keep the capsule out of the reach of children.
Check the expiration date before use and never take the medicine if it's past this date.

To help manage conditions treated by Dabigatrex 150 Capsule 10, consider maintaining a balanced diet with plenty of fruits and vegetables. These foods are rich in vitamins that support good blood health and help reduce the risk of blood clots.
Limit alcohol intake while you are taking this medicine. Alcohol can increase your risk of bleeding, a potential side effect of Dabigatrex 150 Capsule 10.

Fact Box

Drug Category	Direct Thrombin Inhibitor
Therapeutic Category	Anticoagulant
Available Dosage Types	Capsule
Habit Forming	No
Ailment	Stroke, Deep Vein Thrombosis, Pulmonary Embolism

What is Dabigatrex 150 Capsule 10 used for?

Dabigatrex 150 Capsule 10 is primarily used to manage blood clot formation, reducing the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation.

How does Dabigatrex 150 Capsule 10 work?

The active ingredient, dabigatran etexilate, in Dabigatrex 150 Capsule 10 inhibits thrombin, a key enzyme involved in blood clotting, thus reducing the formation of blood clots.

Can I chew or crush the Dabigatrex 150 Capsule 10?

No, the capsules should be swallowed whole with water. Chewing or crushing them can alter the medicine's effectiveness.

What are the common side effects of this medicine?

Common side effects include stomach pain, indigestion, frequent loose or liquid bowel movements (diarrhoea), nausea, and increased risk of bruising or bleeding.

Is it safe to take Dabigatrex 150 Capsule 10 during pregnancy or while breastfeeding?

It's recommended to consult your doctor before taking this medicine during pregnancy or breastfeeding as it is not typically recommended for use during these periods.

Can I consume alcohol while taking this medicine?

Avoid alcohol while on this medication as it can increase the risk of bleeding. Always consult your doctor for personalized advice.

Are there any precautions I should take before starting this medication?

Yes, inform your doctor if you have an active bleeding disorder, organ diseases like stomach ulcers or severe kidney or liver dysfunction, recent fractures, head injuries or surgeries.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Saniya K Mulla

Medical Writer & Reviewer | 5 years

MBBS

Check out Editorial Policy

Manufacturer details

Tanaji Chowk, Ambedkar Nagar, Kurla West, Kurla, Mumbai, Maharashtra 400070

Country of origin: INDIA

References

U.S. Food and Drug Administration. (2012). Pradaxa: Highlights of prescribing information. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022512s016lbl.pdf
Dabigatran etexilate: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06695
Dabigatran Etexilate Accord | European Medicines Agency (EMA). (n.d.). European Medicines Agency (EMA). https://www.ema.europa.eu/en/medicines/human/EPAR/dabigatran-etexilate-accord
Cheng, J. W. M., & Vu, H. (2012). Dabigatran Etexilate: An Oral Direct Thrombin Inhibitor for the Management of Thromboembolic Disorders. Clinical Therapeutics, 34(4), 766–787. https://doi.org/10.1016/j.clinthera.2012.02.022

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