Daparyl 5 Mg Tablet 10

Daparyl 5 Tablet 10

Intas Pharmaceuticals Ltd

Strip of 10 Units

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Composition

Dapagliflozin (5 Mg)

Strength:

5 MG 10 MG

Daparyl 5 Tablet 10 is primarily used to manage type 2 diabetes mellitus in adults. It is a part of the group of medicines known as sodium-glucose co-transporter 2 (SGLT2) inhibitors.

This tablet also assists in reducing the risk of hospitalization due to heart failure in type 2 diabetes mellitus patients who have established cardiovascular disease or multiple risk factors. It can be used alone or in combination with other antidiabetic medicines, depending on the individual patient's requirements.

Before starting this medicine, it's crucial to consult your doctor, who will guide you on the correct dosage and frequency. Do share any pre-existing conditions or ongoing medications with your doctor, as this can influence how this tablet works for you. If you notice any side effects while taking this medicine, inform your doctor promptly. For optimum results, continue taking the medicine for the duration prescribed by your doctor.

Daparyl 5 Tablet 10 is used for the following:

Enhancing control of blood glucose levels in adults with type 2 diabetes mellitus
Complementing diet and exercise for better management of type 2 diabetes
Working in conjunction with other antidiabetic medications like metformin, sulfonylureas, thiazolidinediones, DPP-4 inhibitors, and insulin
Reducing the likelihood of hospitalization due to heart failure in adult patients with type 2 diabetes and established cardiovascular disease or multiple risk factors

Directions for Use of Daparyl 5 Tablet 10

Swallow the tablet whole with a glass of water.
Avoid crushing, breaking, or chewing the tablet.
The medicine can be taken in the morning, either before or after meals.
Always stick to your doctor's recommended dose and never exceed it without consulting your doctor.

Daparyl 5 Tablet 10 is taken orally.

Daparyl 5 Tablet 10 may have the following common side effects:

Urinary tract infections
Back pain
Genital mycotic infections: These are yeast infections in the genital area.
Nasopharyngitis: This is an inflammation of the nasal passages and throat, commonly known as a cold.
Polyuria: This means you might urinate more than usual.
Dysuria: This refers to painful or difficult urination.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which are resolved by discontinuing the use of Daparyl 5 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Polyuria: Try taking Daparyl 5 Tablet 10 in the morning to lessen its impact on your sleep pattern.
Dysuria: Drinking plenty of fluids may help ease this effect.

Daparyl 5 Tablet 10 contains dapagliflozin (5 mg), which carries out its action on the body as follows:

SGLT2 Inhibition: Dapagliflozin functions by blocking a protein called SGLT2 in your kidneys. SGLT2 is mainly responsible for reabsorbing glucose back into your body from your kidneys.
Reduces Blood Glucose: By inhibiting SGLT2, dapagliflozin effectively reduces glucose reabsorption and promotes urinary glucose excretion. This process helps lower blood glucose levels and manage type 2 diabetes mellitus effectively.

Pregnancy

Caution is advised while taking Daparyl 5 Tablet 10 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Daparyl 5 Tablet 10 is not recommended while breastfeeding due to the potential for serious adverse reactions in a breastfed infant. Consult your doctor to understand the potential risks and benefits.

Alcohol

Caution is advised when consuming alcohol if this medication is prescribed to you as alcohol can affect glucose levels.

Liver

No dosage adjustment is necessary for patients with mild or moderate liver impairment. However, Daparyl 5 Tablet 10 hasn't been studied in patients with severe liver impairment. It's advisable to talk to your doctor if you have any liver-related issues.

Kidney

Daparyl 5 Tablet 10 isn't recommended for patients with severe renal impairment, end-stage renal disease, or those on dialysis. If you have any kidney health concerns, consult your doctor before starting this medication.

Using Machines & Driving

There aren't any known restrictions on using machinery or driving while taking Daparyl 5 Tablet 10. However, ensuring you're fully alert and capable before undertaking such tasks is always wise.

Allergy

Daparyl 5 Tablet 10 is contraindicated in patients who have had serious hypersensitivity reactions to dapagliflozin, like anaphylaxis or angioedema. If you've had allergies to any medicine before, make sure to discuss this with your doctor.

Children

Daparyl 5 Tablet 10 isn't recommended for children as its safety and effectiveness haven't been established in pediatric patients.

Older Patients

Older patients should take Daparyl 5 Tablet 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Older patients might also have liver and kidney issues and might be on other medications. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Daparyl 5 Tablet 10 interacts with the following medicines:

Insulin or insulin secretagogues: When used with Daparyl 5 Tablet 10, medicines like glimepiride or glipizide may increase the risk of low blood sugar levels (hypoglycemia).
UGT enzyme inducers: Medicines like rifampin, phenytoin, phenobarbital, and ritonavir may reduce the effectiveness of Daparyl 5 Tablet 10.

Drug-Food Interactions

There are no known specific food interactions with Daparyl 5 Tablet 10. However, a healthy diet is always important in managing diabetes.

Drug-Disease Interactions

Daparyl 5 Tablet 10 interacts with the following diseases:

Liver disease: The effectiveness of Daparyl 5 Tablet 10 may be reduced in patients with liver disease.
Renal disease: Daparyl 5 Tablet 10 is not recommended for those with severe kidney impairment, end-stage kidney disease, or on dialysis.
Heart disease: Patients with heart conditions should use Daparyl 5 Tablet 10 cautiously as it can cause dehydration and low blood pressure.
Urinary tract infections: Daparyl 5 Tablet 10 can increase the risk of urinary tract infections. It should be used cautiously by patients prone to such infections.

Daily Dose

You should take Daparyl 5 Tablet 10 as instructed by your doctor. The dosage may vary based on individual factors, such as your response to the treatment and the severity of your condition. Always follow your doctor's prescribed dosage and never exceed it without consulting your doctor.

Over Dose

If you accidentally take more than the prescribed dose of Daparyl 5 Tablet 10, you may experience common side effects like frequent urination, back pain, or urinary tract infections. If these symptoms persist, consult your doctor.

Missed Dose

If you forget to take a dose of Daparyl 5 Tablet 10, take it as soon as you remember. But if it's nearing the time for your next dose, skip the missed one and continue with your regular dosage schedule. Never increase your dosage without consulting your doctor.

Store Daparyl 5 Tablet 10 at room temperature store below 30°C.
Keep it within the original packaging to safeguard it from moisture and light.
Maintain a safe distance from children's reach.

Opt for a balanced diet abundant in fibers, whole grains, and lean proteins.
Engage in regular physical activity like walking or cycling.

Fact Box

Drug Category	SGLT2 Inhibitor
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus, Established Cardiovascular Disease

What is Daparyl 5 Tablet 10 used for?

Daparyl 5 Tablet 10 manages type 2 diabetes in adults, alongside a balanced diet and regular exercise.

How does Daparyl 5 Tablet 10 work?

It contains dapagliflozin, which inhibits SGLT2, a protein involved in glucose reabsorption in the kidneys, thus reducing blood sugar levels.

Can Daparyl 5 Tablet 10 be taken with other medicines?

Yes, it can be used with other antidiabetic medicines, but always consult your doctor before starting any new medication.

What are the possible side effects of Daparyl 5 Tablet 10?

Possible side effects include genital infections, urinary tract infections, back pain, increased urination, and changes in blood lipid levels. Please consult the doctor if they persist.

Who should not take Daparyl 5 Tablet 10?

Those with severe kidney disease, on dialysis, or with a history of serious allergic reactions to dapagliflozin should not take Daparyl 5 Tablet 10.

How should I store Daparyl 5 Tablet 10?

Store Daparyl 5 Tablet 10 at room temperature below 30°C, away from moisture and light. Keep it out of reach of children.

What should I do if I overdose on Daparyl 5 Tablet 10?

In case of an overdose, you may experience common side effects like frequent urination, back pain, or urinary tract infections, seek immediate medical attention.

Certified Content

Written by

Dr Vatsalya D Ghanekar

Medical Content Writer | 5 years

MD Ayurveda

Reviewed by

Dr. Divya Chauhan

Medical Writer & Reviewer | 6 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

Corporate House, Near Sola Bridge, S. G. Highway, Thaltej, Ahmedabad 380054, Gujarat, India

Country of origin: INDIA

References

Dapagliflozin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06292
Dapagliflozin: MedlinePlus Drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a614015.html
HIGHLIGHTS OF PRESCRIBING INFORMATION. (2020). https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/202293s021lbl.pdf
National Institute of Diabetes and Digestive and Kidney Diseases. (2023, February 10). Sodium-glucose cotransporter-2 (SGLT2) inhibitors. LiverTox - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK548289/
Website, N. (2024, March 20). Dapagliflozin. nhs.uk. https://www.nhs.uk/medicines/dapagliflozin/

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