Darba 40 MCG Injection 0.40 ML

Rpg Life Sciences Ltd.

Pre-filled syringe of 0.40 ML

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MRP ~~₹2200.00~~

₹1760.00

₹5500.00/ML

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Prescription required for this medicine

Store in refrigerator or (2^o - 8^o C) Do Not Freeze

Composition

Darbepoetin Alfa (0.04 Mg)

Darba 40 MCG Injection is primarily used to manage anaemia associated with chronic kidney disease, and it belongs to the class of medicines known as erythropoiesis-stimulating agents.

It is also prescribed to manage anaemia in cancer patients undergoing chemotherapy, which helps in decreasing the need for red blood cell transfusions.

Before starting this medicine, consult your doctor to determine the correct dosage and frequency. Inform your doctor about any existing health conditions or medications you are taking. If you experience any side effects, notify your doctor immediately. For optimal results, ensure that you complete the prescribed course of this medicine as advised.

Darba 40 MCG Injection is used for the following:

Anaemia associated with chronic kidney disease

Directions for Use of Darba 40 MCG Injection 0.40 ML

A healthcare professional usually gives this medicine. It is administered via a subcutaneous route.
Be aware that this medicine is for injection only. Do not attempt to swallow or apply it topically.
Always consult your doctor for specific advice on how to use this medication.

Darba 40 MCG Injection is administered through the subcutaneous or intravenous routes, which involves injecting it under the skin or veins.

Side Effects of Darba 40 MCG Injection 0.40 ML

Darba 40 MCG Injection may have the following common side effects:

High blood pressure
Diarrhoea
Swelling of the hands, feet, or legs
Headaches

Managing the Side Effects:

Most side effects are temporary and generally harmless and resolve upon discontinuation of this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Regular monitoring of blood pressure can help manage hypertension if it develops.

How Darba 40 MCG Injection 0.40 ML Works?

Darba 40 MCG Injection contains the following component:

Darbepoetin Alfa (0.04 Mg): Darbepoetin Alfa is a synthetic erythropoiesis-stimulating agent that stimulates the bone marrow, the soft tissue inside our bones responsible for producing red blood cells. By binding to and activating erythropoietin receptors on red blood cell precursors in the bone marrow, it regulates the final maturation of red blood cells.

Pregnancy

This medicine should not be used during pregnancy unless your doctor advises.

Breastfeeding

This medicine should not be used by breastfeeding mothers. Consult your doctor before using it if you are nursing.

Alcohol

Consult your doctor regarding alcohol consumption during treatment with Darba 40 MCG Injection, as it may interfere with the medication's efficacy or increase side effects.

Liver

If you have liver health issues, it is advised to consult your doctor before using Darba 40 MCG Injection. Your doctor can assess if this medicine is suitable for you, considering your health status.

Kidney

Caution is advised while taking this injection if you have kidney problems. If you have kidney-related health issues, inform your doctor before using Darba 40 MCG Injection. They will evaluate your condition to determine if the medication is safe.

Using Machines & Driving

Darba 40 MCG Injection does not cause dizziness. This won’t interact with your ability to drive or operate heavy machinery.

Allergy

Avoid this medicine if you are allergic to Darbepoetin Alfa or any other Darba 40 MCG Injection components. Inform your doctor about all known allergies before starting this medication.

Children

Darba 40 MCG Injection should not be given to children unless specifically prescribed by a doctor.

Older Patients

Older patients should take Darba 40 MCG Injection under medical supervision as they may be more susceptible to its side effects, particularly regarding kidney and liver health. It is advisable to discuss any health-related concerns with your doctor before starting this medicine.

Interactions of Darba 40 MCG Injection 0.40 ML

Drug-Drug Interactions

Darba 40 MCG Injection has no noted interactions with other medications.

Drug-Food Interactions

There are no specific food items known to interact negatively with Darba 40 MCG Injection.

Drug-Disease Interactions

Darba 40 MCG Injection can interact with the following diseases:

Uncontrolled hypertension: This medicine is contraindicated in patients with uncontrolled hypertension as it may aggravate the blood pressure.

Dosage of Darba 40 MCG Injection 0.40 ML

Daily Dose

Your doctor will prescribe the daily dose of Darba 40 MCG Injection. This may vary depending on your health status and how well you respond to the medicine. It is crucial to follow your doctor's instructions and not alter the dosage without consulting them first.

Over Dose

An overdose is highly unlikely for this medication as a skilled healthcare professional administers it.

Missed Dose

If you forget to take a dose of Darba 40 MCG Injection as scheduled, consult your doctor for next appointment.

Store Darba 40 MCG Injection in a cool, dry place.
Keep it away from direct light.
Ensure the injection is kept out of reach of children.
Always check the expiration date before use and do not use the injection if it has expired.

Regular monitoring of iron levels in the body is recommended as Darbepoetin Alfa works optimally when the body has adequate iron stores.
Regular follow-ups with the doctor are suggested for the timely monitoring of red blood cell count and haemoglobin levels.

Fact Box

Drug Category	Synthetic erythropoiesis-stimulating agent
Therapeutic Category	Renal
Available Dosage Types	Injection
Habit Forming	No
Ailment	Anaemia

What is Darba 40 MCG Injection used for?

Darba 40 MCG Injection is used to manage anaemia caused by chronic kidney disease or chemotherapy in cancer patients, reducing the need for blood transfusions.

How does Darba 40 MCG Injection work?

It contains Darbepoetin Alfa, which stimulates the bone marrow to produce more red blood cells by activating erythropoietin receptors, aiding in the treatment of anaemia.

How is Darba 40 MCG Injection given?

This injection is administered under the skin (subcutaneously) or into a vein (intravenously) by a healthcare professional as per the doctor’s prescription.

What are the common side effects of Darba 40 MCG Injection?

Common side effects include high blood pressure, fatigue, headache, joint pain, and injection site reactions such as redness or swelling.

Can pregnant or breastfeeding women use Darba 40 MCG Injection?

Pregnant or breastfeeding women should use this medicine only if prescribed by a doctor, as its safety for these groups is not fully established.

What precautions should I take while using Darba 40 MCG Injection?

Inform your doctor about any existing conditions like hypertension or a history of strokes. Regular monitoring of haemoglobin levels and blood pressure is essential during treatment.

How should Darba 40 MCG Injection be stored?

Store it in a refrigerator at 2°C to 8°C, away from light, and do not freeze. Keep it out of reach of children.

Last Updated On 24 Jan. 2025 | 10:54AM (IST)

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 6 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 11 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

RPG House, 463, Dr. Annie Besant Road, Worli, Mumbai 400030

Country of origin: INDIA

References

FDA (n.d.). Darbepoetin Alfa. Retrieved July 1, 2024, from https://www.fda.gov/media/73138/download
MedlinePlus. (2018). Darbepoetin alfa injection. https://medlineplus.gov/druginfo/meds/a604022.html
National Center for Biotechnology Information (2024). PubChem Substance Record for SID 440790648, darbepoetin alfa, Source: Drug Induced Liver Injury Rank (DILIrank) Dataset. Retrieved August 19, 2024 from Drug-Induced https://pubchem.ncbi.nlm.nih.gov/substance/440790648
Darbepoetin alfa. (n.d.). DrugBank Online | Database for Drug and Drug Target Info. https://go.drugbank.com/drugs/DB00012
ARANESP- darbepoetin alfa injection, solution ARANESP- darbepoetin alfa solution. (n.d.). DailyMed. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0fd36cb9-c4f6-4167-93c9-8530865db3f9

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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