Diamicron Mex 60500 Mg Tablet Xr 14

Diamicron Xr Mex 500 Tablet 14

Serdia Pharmaceuticals (india) Pvt. Ltd.

STRIP of 15 Units
STRIP of 14 Units

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Composition

Gliclazide (60 Mg) + Metformin (500 Mg)

Diamicron XR Mex 500 Tablet is primarily used in the management of type 2 diabetes mellitus. It is a combination medicine that falls under the category of anti-diabetic medications.

In addition to its main use, this medicine also plays a crucial role when diet and exercise alone are insufficient to maintain optimal blood sugar levels. It is particularly useful when single-agent therapy fails to achieve control over blood glucose levels.

Consult your doctor for the appropriate dosage and frequency of use of this medication before taking it. Any current medications or pre-existing diseases should be disclosed to your doctor. Notify your doctor immediately if you have any adverse side effects while taking this medicine. Continue taking the medication for the entire period recommended by your doctor for the best outcomes.

Diamicron XR Mex 500 Tablet is used for:

Managing type 2 diabetes mellitus,
when diet and exercise alone do not suffice
Improving insulin sensitivity in peripheral tissues
Controlling glucose production in the liver

Directions for Use of Diamicron Xr Mex 500 Tablet 14

Here's how to take Diamicron XR Mex 500 Tablet:

Swallow the tablet whole with water or food, ideally at the same time each day.
Avoid crushing, chewing, or dividing the tablet.
You should always get your doctor's approval before stopping this medication, even if you feel okay or your blood sugar readings are within normal limits.

Diamicron XR Mex 500 Tablet is taken orally.

Side Effects of Diamicron Xr Mex 500 Tablet 14

Diamicron XR Mex 500 Tablet may have the following common side effects:

Headache
Dizziness
Diarrhoea
Nausea

Managing the Side Effects:

Most side effects are temporary and usually mild, and they go away after the Diamicron XR Mex 500 Tablet is discontinued. See your doctor, however, if you experience severe side effects or if your symptoms get worse.

Here are some general guidelines for managing common side effects:

Diarrhoea: Try taking Diamicron XR Mex 500 Tablet with food or milk.
Nausea: Consider taking this medicine after meals to lessen this effect.

How Diamicron Xr Mex 500 Tablet 14 Works?

Diamicron XR Mex 500 Tablet contains two key components:

Gliclazide (60 mg): Gliclazide belongs to a class of substances called sulfonylurea, which stimulates beta cells in the pancreas to secrete more insulin. This aids in lowering blood glucose levels. It also improves insulin sensitivity in peripheral tissues, i.e., tissues that are not of primary concern to the function of an organ.
Metformin hydrochloride (500 mg): This component decreases glucose production in the liver and increases insulin sensitivity. It further improves glucose absorption and utilization by peripheral tissues.

This combination provides a synergistic effect, aiding in the effective management of blood sugar levels.

Pregnancy

Caution is advised while taking Diamicron XR Mex 500 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Diamicron XR Mex 500 Tablet should be taken with care if you are breastfeeding. Consult your doctor before taking this medicine.

Alcohol

Avoid consuming alcohol while taking this medicine, as it may increase the risk of hypoglycaemia as well as a condition called lactic acidosis.

Liver

If you have mild to moderate liver impairment, caution is advised while taking Diamicron XR Mex 500 Tablet. It is not recommended for individuals with severe liver impairment. Discuss your liver health concerns with your doctor before starting this medication.

Kidney

In case of a history of kidney disease or impairment, it's advisable to discuss these issues with your doctor before starting Diamicron XR Mex 500 Tablet.

Using Machines & Driving

Diamicron XR Mex 500 Tablet may cause dizziness. Until you know how this medicine affects you, avoid driving or operating machinery.

Allergy

If you are allergic to gliclazide, metformin, or any other ingredients in Diamicron XR Mex 500 Tablet, avoid taking this medicine. If you experience any allergic reactions, contact your doctor immediately.

Children

Diamicron XR Mex 500 Tablet is not recommended for use in children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Diamicron XR Mex 500 Tablet under medical supervision, as they may be more susceptible to its side effects. Caution is advised if patients are over 70 years of age.

Interactions of Diamicron Xr Mex 500 Tablet 14

Drug-Drug Interactions

Diamicron XR Mex 500 Tablet interacts with the following medicines:

Antidiabetic medications: Diamicron XR Mex 500 Tablet might amplify the glucose-lowering effect of other diabetic medications, leading to hypoglycaemia. Some specific medicines include insulin, glimepiride, and pioglitazone.
Corticosteroids: Steroids like prednisone and dexamethasone can raise blood glucose levels, counteracting the glucose-lowering effect of Diamicron XR Mex 500 Tablet.
Thiazide diuretics: Medicines from this class of diuretics, like hydrochlorothiazide and chlorthalidone, can increase blood sugar, thereby reducing the glucose-lowering effect of Diamicron XR Mex 500 Tablet.

Drug-Food Interactions

Certain foods might interact with Diamicron XR Mex 500 Tablet, altering its effectiveness:

High-fat meals: They might delay the release of gliclazide from the tablet, affecting blood sugar control.

Drug-Disease Interactions

Diamicron XR Mex 500 Tablet interacts with the following diseases:

Kidney impairment: This medication could accumulate in your body if you have kidney issues, increasing your risk of side effects.
Liver disease: Liver problems can impact how this medicine is metabolised and eliminated, potentially raising the risk of side effects.
Surgical procedures: Surgery or injury could affect how your body manages glucose; your doctor might need to adjust your dosage around these situations.

Dosage of Diamicron Xr Mex 500 Tablet 14

Daily Dose

It's vital to take the daily dose of Diamicron XR Mex 500 Tablet as advised by your doctor. The amount is based on the severity of your condition and your response to the medication. Do not alter the prescribed dosage without talking with your doctor.

Over Dose

Taking more than the prescribed dose of Diamicron XR Mex 500 Tablet can lead to symptoms like low blood sugar, headache, and dizziness. If you have taken too many tablets and are experiencing these symptoms, inform your doctor promptly.

Missed Dose

If you forget to take your Diamicron XR Mex 500 Tablet at the usual time, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed tablet and resume your regular schedule. Avoid increasing your dosage without a consultation with your doctor.

Store the medicine at room temperature in a cool, dry place, away from direct sunlight and moisture.
Keep the tablet out of reach of children.
Always check the expiration date before using the medicine.

Maintain a balanced diet low in sugar and high in fibre to help manage your blood glucose levels. This will complement the action of this medicine.
Regular physical activity assists in maintaining optimum blood sugar levels. Aim for a minimum of 150 minutes of moderate-intensity exercise per week, such as brisk walking or cycling.

Fact Box

Drug Category	Pancreatic Stimulant, Glucose Production Reducer
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus

What is Diamicron XR Mex 500 Tablet used for?

This medicine is used to manage type 2 diabetes in adults when diet and exercise fail to control blood sugar levels.

Can Diamicron XR Mex 500 Tablet cause hypoglycaemia?

Yes, one possible side effect of this medicine is hypoglycaemia, which is lower than normal blood sugar levels.

Is it safe to consume alcohol while taking Diamicron XR Mex 500 Tablet?

Consumption of alcohol should be avoided or limited, as it can increase the risk of hypoglycaemia and lactic acidosis.

Can long-term use of Diamicron XR Mex 500 Tablet lead to vitamin B12 deficiency?

Yes, metformin, one of the ingredients in this medicine, may cause vitamin B12 deficiency with long-term use.

How should I take Diamicron XR Mex 500 Tablet?

You should take this medicine as directed by your doctor. Do not crush, chew, or divide the tablet; swallow it whole.

What precautions should I take while using Diamicron XR Mex 500 Tablet?

Use this medicine with caution if you have mild to moderate kidney or liver impairment; it's not recommended for severe cases.

What should I do if I miss a dose of Diamicron XR Mex 500 Tablet?

If you miss a dose, take it as soon as you remember, unless it's nearly time for the next dose; then skip the missed dose. Do not double up on doses to compensate for the missed dose.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Parinee Crescenzo, Floor No. 1703, Plot No. C38 & 39, 17th Floor B Wing, behind MCA, G Block BKC, Bandra Kurla Complex, Bandra East, Mumbai, Maharashtra 400051

Country of origin: INDIA

References

U.S. Food and Drug Administration. (2017, Apr). Glucophage (metformin hydrochloride) tablets label. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020357s037s039,021202s021s023lbl.pdf
National Center for Biotechnology Information (2024). PubChem compound summary for CID 3475, gliclazide. https://pubchem.ncbi.nlm.nih.gov/compound/Gliclazide.
Al-Gareeb, A. I., Alrubai, H. F., & Suliaman, S. M. (2016). Effects of gliclazide add on metformin on serum omentin-1 levels in patients with type 2 diabetes mellitus. Indian journal of endocrinology and metabolism, 20(2), 195–198. https://doi.org/10.4103/2230-8210.176355
DrugBank Online. (2024, May 14). Metformin. https://go.drugbank.com/drugs/DB00331
DrugBank Online. (2024, May 15). Gliclazide. https://go.drugbank.com/drugs/DB01120
U.K. National Health Services. (n.d.). Gliclazide. NHS. https://www.nhs.uk/medicines/gliclazide/
U.K. National Health Services. (n.d.). Metformin. NHS. https://www.nhs.uk/medicines/metformin/

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