Distinon 60 Mg Tablet 10

Distinon Tablet 10

Samarth Life Sciences Pvt Ltd

Strip of 10 Units

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MRP ~~₹112.11~~

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₹11.21/Units

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Composition

Pyridostigmine (60 Mg)

Distinon Tablet is primarily used to manage myasthenia gravis, a condition that causes muscle weakness and fatigue. This medicine belongs to the group of cholinesterase inhibitors.

In addition to managing myasthenia gravis, this tablet is also used to help manage paralytic ileus, a condition where the muscles in the intestines become paralysed leading to constipation and blockage. Moreover, it can be used to manage post-surgical urinary retention by improving bladder muscle contractions.

Before you start taking this medicine, it is important to consult your doctor who will determine the appropriate dosage and frequency for you. Let your doctor know about any existing diseases or ongoing medications. If you notice any side effects, inform your doctor immediately. Make sure you continue taking the medicine for the entire duration prescribed to you by your doctor.

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Distinon Tablet is used for the following:

Management of myasthenia gravis, a condition causing muscle fatigue and weakness.
Alleviating paralytic ileus, where the intestines' muscles become paralyzed leading to constipation.
Improvement of bladder muscle contractions after surgery to reduce urinary retention.

Directions for Use of Distinon Tablet 10

Here are some instructions to follow while taking Distinon Tablet:

Swallow the tablet whole with a glass of water.
Avoid crushing or chewing the tablet.
Do not exceed the recommended dose without consulting your doctor.
It's important not to stop taking this medicine without speaking to your doctor first.

Distinon Tablet is taken orally.

Distinon Tablet may have the following common side effects:

Nausea
Vomiting
Diarrhoea
Abdominal cramps
Bradycardia: This is a slower than normal heart rate.
Hypotension: Low blood pressure, which may make you feel faint.
Miosis: This refers to constricted pupils.
Increased bronchial secretions: This could cause coughing or breathing difficulties.
Muscle cramps
Fasciculations: These are small, local, involuntary muscle contractions visible under the skin.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Distinon Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Consume plenty of water and healthy fluids to avoid dehydration.
Hypotension: If you feel dizzy or faint after taking this medicine, consider taking it at bedtime.

Distinon Tablet contains Pyridostigmine (60 mg), which acts on your body as follows:

Inhibits Acetylcholinesterase: Pyridostigmine works by blocking an enzyme in your body called acetylcholinesterase. This enzyme plays a significant role in breaking down acetylcholine, a chemical that transmits signals between nerve cells and muscles.
Increases Acetylcholine Levels: By inhibiting the action of acetylcholinesterase, pyridostigmine effectively increases the levels of acetylcholine at the junction between nerves and muscles. This results in improved muscle strength and reduced fatigue, helping to manage the symptoms of myasthenia gravis.

Pregnancy

Caution is advised while taking Distinon Tablet if you're pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, discuss this with your doctor before starting Distinon Tablet. They will evaluate if this medicine is suitable.

Alcohol

There is no known interaction between alcohol and Distinon Tablet. However, it's always a good idea to check with your doctor.

Liver

This medicine is often prescribed for older patients, who may be more susceptible to liver health issues. It is advisable to discuss liver-related concerns with your doctor before starting treatment with Distinon Tablet.

Kidney

Caution is advised before using Distinon Tablet if you have a history of any kidney problems. It's a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

Distinon Tablet might cause drowsiness or dizziness in some patients. If you experience these symptoms, avoid driving or operating heavy machinery.

Allergy

This medicine should not be taken if you have allergies to pyridostigmine or any other ingredients in the formulation.

Children

Caution is advised while giving Distinon Tablet to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Distinon Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Distinon Tablet interacts with the following medicines:

Anticholinesterases: If you are already taking other anticholinesterase medicines like neostigmine, the use of Distinon Tablet may increase cholinergic effects and the risk of side effects.
Muscarinic Antagonists: Medicines like atropine and glycopyrrolate could reduce the effectiveness of Distinon Tablet.
Beta-blockers: Medications such as propranolol or metoprolol taken along with Distinon Tablet may intensify bradycardia, a slow heart rate condition.
Aminoglycosides: Antibiotics like gentamicin or amikacin could result in increased neuromuscular blockade if taken alongside Distinon Tablet.

Drug-Food Interactions

There are no known specific food interactions with Distinon Tablet.

Drug-Disease Interactions

Distinon Tablet interacts with the following diseases:

Bradycardia: If you have a slow heart rate, using this medicine requires caution as it might exacerbate the condition.
Peptic Ulcer: Patients suffering from stomach ulcers should be cautious while taking this medication as it might worsen their condition.
Seizures: The medicine potentially lowers the seizure threshold, hence should be used with caution in patients having a history of seizures.
Asthma: Pyridostigmine present in Distinon Tablet can increase bronchial secretions and may worsen symptoms in those having asthma.

Daily Dose

Your doctor will decide on the specific daily dosage of Distinon Tablet for you. This will be based on your individual condition and how you respond to the medicine. Always follow your doctor's instructions closely and never exceed the prescribed dose.

Over Dose

If you accidentally take more than the prescribed amount of Distinon Tablet, you may experience symptoms such as increased muscle weakness, difficulty in breathing, and slower heart rate. In such a case, inform your doctor right away.

Missed Dose

If you miss a dose of Distinon Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never increase your dose without consulting your doctor to make up for a missed one.

Store your Distinon Tablet at room temperature, ideally below 25°C.
Keep it in a tightly closed container to protect it from moisture and heat.
Avoid exposing the medicine to direct light.
Always keep the medicine away from children and pets.
Remember to use it before the expiry date mentioned on the pack.

If you're dealing with myasthenia gravis, a condition managed by Distinon Tablet, consider incorporating mild physical exercise into your routine. This can help strengthen your muscles and reduce weakness.
For those diagnosed with paralytic ileus, another condition that Distinon Tablet helps manage, maintaining a high-fibre diet could be beneficial. More fibre can stimulate movement in your intestines and help prevent constipation or blockages.

Fact Box

Drug Category	Cholinesterase Inhibitor
Therapeutic Category	Neuromuscular Medication
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Myasthenia Gravis, Paralytic Ileus

What is Distinon Tablet used for?

Distinon Tablet is a medicine used to manage conditions such as myasthenia gravis and paralytic ileus by improving muscle strength and stimulating muscle contractions.

How does Distinon Tablet work?

It contains pyridostigmine, which prevents the breakdown of a neurotransmitter called acetylcholine, improving nerve impulse transmission to muscles and reducing fatigue.

Can I take Distinon Tablet with my other medications?

Certain medications may interact with Distinon Tablet. Always inform your doctor about all the medicines you're taking to ensure usage is safe.

What are the side effects of Distinon Tablet?

Side effects may include nausea, vomiting, diarrhoea, abdominal cramps, bradycardia (slow heart rate), hypotension (low blood pressure), and increased salivation.

Is Distinon Tablet safe during pregnancy or breastfeeding?

The safety of Distinon Tablet during pregnancy and breastfeeding is not well established. Consult your doctor if you are pregnant or nursing.

What should I do If I miss a dose of Distinon Tablet?

If you miss a dose, take it as soon as you remember unless it's near the time for your next scheduled dose. Never double up on doses.

What should I do in case of an overdose of Distinon Tablet?

In case of an overdose, seek immediate medical attention. Symptoms may include muscle weakness, breathing difficulties, excessive secretions, slow heart rate, and loss of consciousness.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Opp. Moviestar, Ram Mandir, Gulmohar Road, Goregaon West, Mumbai, Maharashtra 400104

Country of origin: INDIA

References

Unknown. (n.d.). Pyridostigmine Bromide Package Insert. In Pyridostigmine Bromide Package Insert (pp. 1–4). https://www.fda.gov/media/75559/download
DailyMed - PYRIDOSTIGMINE BROMIDE tablet. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=91ca7bcf-d2cc-4cb3-bfbe-c294fd707524
Pyridostigmine: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00545
Pyridostigmine: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a682229.html

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