Diziron 25 Mg Tablet 20

Diziron Tablet 20

Glenmark Pharmaceuticals Ltd.

Strip of 20 Units

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Composition

Cinnarizine (25 Mg)

Strength:

75 MG 25 MG

Diziron Tablet is primarily used to manage symptoms of motion sickness and vertigo. It belongs to the class of antihistamines.

Besides motion sickness, this tablet is also used to manage symptoms associated with Ménière's disease and other vestibular disorders. In these conditions, balance and spatial orientation are often impaired, leading to dizziness, vertigo, and nausea. The medicine can help reduce these symptoms, enhancing comfort levels.

Before starting this medicine, it's important that you consult your doctor, who will guide you on the appropriate dosage and frequency. It's vital that you inform your doctor about any pre-existing conditions or ongoing medications you might have. For optimal results, continue taking the medicine as long as prescribed by your doctor.

Diziron Tablet is used for the following:

Managing symptoms of motion sickness, such as nausea, vomiting, and dizziness
Easing vertigo, a sensation of feeling off balance
Helping in Ménière's disease, a condition of the inner ear that causes severe dizziness
Helping in vestibular disorders, related to problems with the body's balance system

You should take Diziron Tablet as follows:

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
For any specific advice on how to take this medicine, consult your doctor.

Diziron Tablet is taken orally.

Diziron Tablet may cause the following common side effects:

Drowsiness and fatigue
Dry mouth
Headaches
Muscle and joint pains
Blurred vision
Skin rashes and eczema: Changes in the skin that may appear as red, itchy patches or small bumps.
Tinnitus: Hearing sounds that aren't there, like ringing in your ears.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Diziron Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, immediately consult your doctor.

Here are some general guidelines for managing common side effects:

Gastrointestinal disturbances: Try taking this tablet after meals to lessen these effects.
Dry mouth: Drinking plenty of fluids or chewing sugar-free gum will help keep your mouth moist.

Diziron Tablet contains cinnarizine (25 mg) which acts on your body in several ways:

Antihistamine Effect: Cinnarizine works by blocking H1 receptors in your body. These receptors bind with histamine, a substance that causes symptoms of motion sickness like nausea and dizziness.
Calcium Channel Blocker: Cinnarizine prevents calcium from entering cells leading to the relaxation of smooth muscles which improves blood circulation.
Vestibular Sedative: The tablet reduces activity in the vestibular apparatus a structure in your inner ear responsible for maintaining balance. This helps relieve vertigo and dizziness.
Anti-dopaminergic Effect: Cinnarizine also targets dopamine D2 receptors found in a part of the brain called the chemoreceptor trigger zone, helping reduce nausea and vomiting.

Pregnancy

Caution is advised while taking Diziron Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Caution is advised while taking Diziron Tablet if you are breastfeeding. It's best to consult your doctor before taking this medicine.

Alcohol

Combining Diziron Tablet with alcohol may increase drowsiness and sedation. It is advisable to avoid alcohol while on this medication. Consult your doctor about risks and safe limits.

Liver

Caution is advised while taking Diziron Tablet if you have any liver health issues. Discuss them with your doctor before starting this medicine.

Kidney

Prior to using Diziron Tablet, it is advisable to consult your doctor if you have a history of kidney issues.

Using Machines & Driving

As Diziron Tablet can cause drowsiness and fatigue, caution should be exercised while driving or operating machinery.

Allergy

Diziron Tablet is contraindicated for those with known hypersensitivity to cinnarizine. Inform your doctor of your allergies before starting this medication.

Children

It's best to consult your doctor before giving Diziron Tablet to children under 18 years of age. It is advised to consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Diziron Tablet under medical supervision due to an increased susceptibility to side effects. Caution is advised if patients are over 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Diziron Tablet interacts with the following medicines:

Central Nervous System Depressants: Diziron Tablet can intensify the sedative effects of certain medications such as benzodiazepines (like diazepam and alprazolam) and opioids (like morphine and codeine), leading to increased drowsiness and slowed breathing.
Anticholinergic Medicines: When combined with anticholinergic medicines like tricyclic antidepressants (like amitriptyline) or antiparkinsonism medicines (like trihexyphenidyl), this medicine can enhance anticholinergic side effects such as dry mouth, blurred vision, and constipation.
CYP2D6 Enzyme Inhibitors: Medicines that inhibit the CYP2D6 enzyme, such as fluoxetine, could potentially increase levels of cinnarizine in the body, possibly enhancing its effects or side effects.

Drug-Food Interactions

Diziron Tablet has no known specific food interactions. However, you should always follow your doctor's advice on dietary restrictions while taking this medicine.

Drug-Disease Interactions

Diziron Tablet interacts with the following diseases:

Parkinson's Disease: Diziron Tablet might worsen symptoms in patients with Parkinson's disease due to its anti-dopaminergic action.
Hypotension: This medicine may lower blood pressure further in people already suffering from low blood pressure or hypotension.
Angle-Closure Glaucoma: This tablet can increase the risk of acute angle-closure glaucoma due to its anticholinergic activity.
Porphyria: Patients with this metabolic disorder should avoid this medicine as it may worsen their condition.

Daily Dose

The daily dose of Diziron Tablet should be taken as prescribed by your doctor. The dosage can vary based on individual factors such as the severity of your condition and how you respond to the medicine. It's crucial to adhere to the prescribed dosage and not to exceed it without consulting your doctor.

Over Dose

If you accidentally take more Diziron Tablet than prescribed, you may feel extremely drowsy or confused. You might also experience symptoms like dry mouth or gastrointestinal disturbances. If these symptoms persist or worsen, inform your doctor immediately.

Missed Dose

If you forget to take your regular dose of Diziron Tablet, take it as soon as you remember. If it's almost time for your next dose, skip the missed one and continue with your regular schedule. Never adjust your dosage without consulting your doctor.

Store Diziron Tablet in a cool, dry place where the temperature stays below 30°C.
Keep it away from direct light and moisture.
Always keep this medication out of reach of children.
Make sure you use any medicine before its expiry date.

If you're experiencing dizziness or vertigo, try to avoid sudden changes in position. Stand up slowly from sitting or lying down to reduce the risk of fainting.
Incorporate some balance exercises into your routine, like yoga, which can help manage conditions like vertigo or Ménière's disease. Always consult your doctor before starting any new exercise regime.

Fact Box

Drug Category	Antihistamine, Calcium Channel Blocker
Therapeutic Category	Antivertigo
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Motion Sickness, Vertigo, and Ménière's Disease

What is Diziron Tablet used for?

Diziron Tablet is used to manage conditions like motion sickness, vertigo, Ménière's disease, and vestibular disorders that cause dizziness, vomiting and nausea.

How does Diziron Tablet work in the body?

Diziron Tablet, containing cinnarizine, blocks certain chemical messengers and calcium influx in cells, aiding in reducing symptoms like dizziness and nausea.

Is it safe to drive or operate machinery after taking Diziron Tablet?

No, Diziron Tablet may cause drowsiness and sedation. You should avoid driving or operating machinery after taking this medicine.

Can I take Diziron Tablet if I am pregnant or breastfeeding?

Consult your doctor before taking Diziron Tablet if you are pregnant or breastfeeding, as the safety of this medicine in these conditions is not fully established.

What happens if I overdose on Diziron Tablet?

Overdosing may cause extreme drowsiness, confusion, and seizures among others. In case of suspected overdose, seek emergency medical attention immediately.

What are the side effects of Diziron Tablet?

Common side effects include drowsiness, dry mouth, headache, and nausea. If any side effect worsens, consult your doctor.

How should I store Diziron Tablet?

Store Diziron Tablet below 30°C, protected from light and moisture to maintain its efficiency.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Divya Chauhan

Medical Writer & Reviewer | 6 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

Glenmark House, HDO-Corporate Building, Wing-A, B.D. Sawant Marg, Chakala Off. Western Express Highway, Andheri (East), Mumbai, Maharashtra, 400099 India

Country of origin: INDIA

References

NHS UK. (n.d.). Cinnarizine. https://www.nhs.uk/medicines/cinnarizine/. Accessed 1 April 2024.
U.S. Food and Drug Administration. (2010). NDA 22-421 Approval Letter. https://www.accessdata.fda.gov/drugsatfda_docs/nda/2010/022421s000NameR.pdf. Accessed 1 April 2024.
Side effects of cinnarizine. (2022, October 25). nhs.uk. https://www.nhs.uk/medicines/cinnarizine/side-effects-of-cinnarizine/
A K Singh, V N Chaturvedi. (n.d.). Prochlorperazine versus cinnarizine in cases of vertigo. PubMed. https://pubmed.ncbi.nlm.nih.gov/23119469/
Cinnarizine/dimenhydrinate for vertigo. (2021). Australian Prescriber, 44(2), 62–63. https://doi.org/10.18773/austprescr.2021.009
Taghdiri, F., Togha, M., Razeghi Jahromi, S., & Refaeian, F. (2014). Cinnarizine for the prophylaxis of migraine associated vertigo: a retrospective study. SpringerPlus, 3(1), 231. https://springerplus.springeropen.com/articles/10.1186/2193-1801-3-231

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