Dm Lef 10 Mg Tablet 10

Dm Lef 10 Tablet 10

Overseas Healthcare Pvt Ltd.

Strip of 10 Units

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MRP ~~₹139.44~~

₹111.55

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Composition

Leflunomide (10 Mg)

Strength:

20 MG 10 MG

DM Lef-10 Tablet is primarily used to manage active rheumatoid arthritis. This medicine is part of a group of medications known as disease-modifying antirheumatic medicines (DMARDs).

It also helps reduce inflammation, swelling, and joint damage associated with this condition. It also inhibits structural damage and helps to improve physical function.

Before you begin taking this medicine, it is important to consult your doctor regarding dosage and frequency. If you are currently on any other medication or have pre-existing health conditions, ensure you inform your doctor. Should you experience any side effects while taking this medicine, notify your doctor without delay. Remember, for optimal results, continue taking the medicine for the duration prescribed by your doctor.

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DM Lef-10 Tablet is used for the following:

Managing symptoms of active rheumatoid arthritis
Inhibiting structural damage
Improving physical function

Directions for Use of Dm Lef 10 Tablet 10

Follow these instructions while taking DM Lef-10 Tablet:

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
Always consult your doctor before changing or stopping the dosage.

DM Lef-10 Tablet is taken orally.

DM Lef-10 Tablet may have the following common side effects:

Diarrhoea
Nausea
Abdominal pain
Oral ulcers: These are sores that appear in the mouth.
Respiratory infection

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of DM Lef-10 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Drink plenty of fluids to avoid dehydration. Oral rehydration solutions, clear broths, and diluted fruit juices can be helpful.
Nausea: Sip on clear fluids like water, herbal teas, or electrolyte drinks to stay hydrated. Small sips of liquids are better tolerated than large amounts.

DM Lef-10 Tablet contains leflunomide (10 mg) which works on your body as follows:

Inhibits Dihydroorotate Dehydrogenase (DHODH): Leflunomide works by blocking a specific enzyme called DHODH in your body. This enzyme plays a crucial role in the production of pyrimidine ribonucleotides, which are essential for the proliferation of rapidly dividing cells.
Reduces Pyrimidine Production: By blocking DHODH, leflunomide effectively decreases the production of pyrimidines. This reduction slows down the proliferation of certain cells, such as activated T-lymphocytes and B-lymphocytes, which are involved in inflammation and joint damage in rheumatoid arthritis.

Pregnancy

DM Lef-10 Tablet is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

DM Lef-10 Tablet is not recommended for breastfeeding women. Consult your doctor to understand the potential risks and benefits.

Alcohol

While taking DM Lef-10 Tablet, it's best to limit your alcohol intake. Ask your doctor for advice on the effect of alcohol intake with this medicine.

Liver

Caution is advised while taking DM Lef-10 Tablet in case of liver impairment. If you have liver problems, discuss them with your doctor before starting DM Lef-10 Tablet.

Kidney

If you have a history of kidney problems, caution is advised before using DM Lef-10 Tablet. It's a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

No specific precautions are required for driving or operating machines while taking DM Lef-10 Tablet. However, if you feel dizzy or unwell after taking this medicine, avoid such activities.

Allergy

If you know you are allergic to leflunomide or any of the other ingredients in DM Lef-10 Tablet, avoid taking this medicine and inform your doctor about your allergies.

Children

DM Lef-10 Tablet should not be given to children as its safety and efficacy have not been established in this age group.

Older Patients

Older patients should take DM Lef-10 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Older patients might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

DM Lef-10 Tablet interacts with the following medicines:

Cholesterol lowering medicines: Administration of cholestyramine or activated charcoal can result in rapid and significant decrease in plasma M1 (the active metabolite of leflunomide).
Anti-tubercular medicines: The levels of leflunomide may increase if patients are to be receiving both DM Lef-10 Tablet and rifampin.

Drug-Food Interactions

There are no specific food items known to interact with DM Lef-10 Tablet.

Drug-Disease Interactions

DM Lef-10 Tablet interacts with the following diseases:

Severe hepatic impairment: The medicine could exacerbate conditions for patients with severe liver disease.
Serious infections: Patients with active serious infections should avoid using this medicine as it may worsen their condition.
Severe immunodeficiency states: Patients with severely impaired immune system should avoid using this tablet.
Bone marrow dysplasia: Patients with bone marrow dysplasia should avoid using this medicine.

Daily Dose

You should take your daily dose of DM Lef-10 Tablet as directed by your doctor. The dosage could vary depending on the severity of your condition and how well you respond to the medicine. It is crucial that you stick to the prescribed dosage and don't exceed it without consulting your doctor.

Over Dose

If you accidentally take more DM Lef-10 Tablets than recommended, you might experience symptoms such as diarrhoea and abdominal discomfort. In such a case, seek advice from your doctor.

Missed Dose

If you forget to take your DM Lef-10 Tablet at the usual time, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. It's important not to increase your dosage without consulting your doctor.

Ensure you store DM Lef-10 Tablet at room temperature.
Keep the medicine in a tightly closed container, protected from light and moisture.
Always keep DM Lef-10 Tablet out of reach of children.
Make sure to use the medicine before its expiry date.

As DM Lef-10 Tablet is used to manage rheumatoid arthritis, maintaining a balanced diet rich in omega-3 fatty acids (found in fish, flaxseeds, and walnuts) can help reduce inflammation.
Regular low-impact exercises such as swimming or cycling can help keep your joints flexible without causing extra strain.

Fact Box

Drug Category	Immunomodulatory Agent
Therapeutic Category	Antirheumatic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Rheumatoid Arthritis, Psoriatic Arthritis

What is DM Lef-10 Tablet used for?

DM Lef-10 Tablet is used to manage active rheumatoid arthritis, a condition causing joint inflammation and damage.

How does DM Lef-10 Tablet work?

DM Lef-10 Tablet contains leflunomide, which reduces the production of certain cells responsible for inflammation, thus decreasing swelling and joint damage.

Can I take DM Lef-10 Tablet if I am pregnant?

No, DM Lef-10 Tablet is not recommended during pregnancy. Always consult your doctor first.

Can DM Lef-10 Tablet cause any side effects?

Yes, common side effects of DM Lef-10 Tablet include diarrhoea, nausea, abdominal pain, and rash. If any side effect persists, consult your doctor immediately.

Can I take DM Lef-10 Tablet with other medicines?

Some medicines can interact with DM Lef-10 Tablet, therefore always inform your doctor about all the medicines you're currently taking.

How should I store DM Lef-10 Tablet?

Store DM Lef-10 Tablet at room temperature in a tightly closed container, away from moisture and light.

What should I do if I overdose on DM Lef-10 Tablet?

In case of an overdose of DM Lef-10 Tablet, seek immediate medical attention. Overdosing can be dangerous and requires urgent medical intervention.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Kanakia Wall Street- B Wing, 1109, 11th Floor, Andheri - Kurla Rd, Andheri East, Maharashtra 400093

Country of origin: INDIA

References

Unknown, U. (2002). ARAVA tablets. In Unknown [Unknown]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2003/20905slr007,20905se1-006_arava_lbl.pdf
ARAVA. (n.d.). ARAVA Tablets (leflunomide) 10 mg, 20 mg, 100 mg. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020905s022lbl.pdf
Padda, I. S., & Goyal, A. (2023, June 3). Leflunomide. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK557799/
Leflunomide: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01097
Leflunomide: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a600032.html

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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