Donep 10 Mg Tablet 15

Donep 10 Tablet 15

Alkem Laboratories Ltd.

Pack of 10 Units
STRIP of 15 Units

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MRP ~~₹293.16~~

₹240.39

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Composition

Donepezil (10 Mg)

Strength:

5 MG 10 MG

Donep-10 Tablet is primarily utilised to manage mild to moderate dementia associated with Alzheimer's disease. This medicine is part of a group of medications known as cholinesterase inhibitors.

In addition to its primary use, this medicine helps improve mental function, memory, and the ability to perform daily activities. However, it does not cure Alzheimer's disease, nor does it prevent the eventual deterioration of mental abilities.

You should take this medicine orally, as directed by your doctor. Be sure to inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you notice any side effects while on this medicine, notify your doctor immediately. Continue taking the medicine for the duration prescribed by your doctor for optimal results.

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Donep-10 Tablet is used for:

Managing mild to moderate dementia in Alzheimer's disease patients
Improving mental function for those with Alzheimer's disease
Enhancing memory in Alzheimer's disease patients
Supporting the ability to perform daily activities in individuals with Alzheimer's disease

Directions for Use of Donep 10 Tablet 15

To ensure effective use of Donep-10 Tablet, please follow these instructions:

Swallow the tablet whole with a glass of water.
Do not crush, chew, or split the tablet.
If you feel better, do not stop taking this medicine without consulting your doctor first.

Donep-10 Tablet is taken orally.

Donep-10 Tablet may have the following common side effects:

Nausea
Vomiting
Diarrhoea
Loss of appetite
Muscle cramps
Fatigue
Trouble sleeping

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Donep-10 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea/Vomiting: Try taking Donep-10 Tablet with food to lessen these effects.
Trouble sleeping: Consider taking this medicine in the evening before bedtime if it disrupts your sleep.

Donep-10 Tablet contains donepezil (10 mg) which works on your body in the following ways:

Inhibits Acetylcholinesterase: Donepezil blocks the action of an enzyme called acetylcholinesterase in your brain. This enzyme is responsible for breaking down acetylcholine, a substance that plays a key role in memory and cognition.
Increases Acetylcholine Levels: By inhibiting the breakdown of acetylcholine, donepezil increases its levels in the brain. This improvement in acetylcholine levels enhances communication between nerve cells, leading to improved mental function.

Pregnancy

Caution is advised while taking Donep-10 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, it's important to discuss this with your doctor before starting Donep-10 Tablet.

Alcohol

Avoid consuming alcohol while on Donep-10 Tablet as it may increase the risk of side effects.

Liver

This medicine is often prescribed for older patients, who may be more susceptible to liver health issues. It is advisable to discuss liver-related concerns with your doctor before starting treatment with Donep-10 Tablet.

Kidney

Caution is advised before using Donep-10 Tablet if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

Donep-10 Tablet may cause dizziness or drowsiness, so exercise caution when driving or operating machinery until you know how the medication affects you.

Allergy

If you are allergic to donepezil or piperidine derivatives, avoid using Donep-10 Tablet as it might trigger allergic reactions.

Children

Caution is advised while giving Donep-10 Tablet to children under 18. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Donep-10 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Donep-10 Tablet interacts with the following medicines:

Anticholinergics: Medicines like atropine or scopolamine interact with Donep-10 Tablet, potentially reducing its effectiveness.
Cholinergic agonists: Medicines like pilocarpine may have their effects amplified when taken in conjunction with Donep-10 Tablet, leading to potential adverse effects.
Antifungals: Medicines such as ketoconazole can alter the metabolism of Donep-10 Tablet, resulting in changes to its efficacy or safety profile.

Drug-Food Interactions

No specific food interactions have been reported with Donep-10 Tablet.

Drug-Disease Interactions

Donep-10 Tablet interacts with the following diseases:

Heart problems: Patients with heart issues should exercise caution as Donep-10 Tablet could potentially exacerbate their condition.
Lung diseases (such as asthma or COPD): Individuals suffering from these conditions should be cautious while taking Donep-10 Tablet as it may aggravate symptoms.
Stomach ulcers: People with stomach ulcers need to be careful when taking this medicine, as it could potentially worsen their condition.
Difficulty urinating due to an enlarged prostate: Men with this condition might experience increased difficulty urinating when taking Donep-10 Tablet.

Daily Dose

The daily dose of Donep-10 Tablet should be ingested as directed by your doctor. The amount may vary based on individual factors such as the intensity of your condition and how your body responds to the medicine. Following the prescribed dosage without crossing the limit set by your doctor is crucial.

Over Dose

In case of an accidental overdose, you might experience more intense versions of common side effects like nausea, vomiting, and diarrhoea. If you suspect you've taken too much of Donep-10 Tablet, inform your doctor.

Missed Dose

If you miss a dose of Donep-10 Tablet, take it as soon as you remember. However, if it's nearing time for the next dose, skip the missed one and continue with your regular dosing schedule. Do not change your dosage without consulting with your doctor.

Store Donep-10 Tablet at room temperature, ideally below 25 degrees Celsius.
Keep it out of direct sunlight and away from moisture.
Make sure the medicine is kept out of reach of children.
Always check the expiry date on the pack before you take the medicine.

Engage in mentally stimulating activities such as puzzles, reading, or learning a new skill to boost brain function and memory retention.
Follow a diet rich in omega-3 fatty acids (found in fish and nuts) which are known to support brain health. However, always consult your doctor before making any major dietary changes.

Fact Box

Drug Category	Cholinesterase Inhibitor
Therapeutic Category	Anti-Dementia
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Alzheimer's Disease, Dementia

What is Donep-10 Tablet used for?

Donep-10 Tablet is used to manage symptoms of mild to moderate dementia in Alzheimer's disease, improving mental function and daily activity performance.

Can Donep-10 Tablet cure Alzheimer's disease?

No, Donep-10 Tablet doesn't cure Alzheimer's disease. It helps manage symptoms and may slow down the disease progression.

How does Donep-10 Tablet work?

Donep-10 Tablet increases levels of a brain chemical called acetylcholine, which helps enhance communication between nerve cells and improve mental function.

What should I do if I forget to take my Donep-10 Tablet?

If you miss a dose, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one.

Can I stop taking Donep-10 Tablet if I feel better?

You should not stop taking Donep-10 Tablet without consulting your doctor as this can cause a worsening of symptoms.

Can Donep-10 Tablet interact with other medicines?

Yes, Donep-10 Tablet can interact with certain medicines, such as anticholinergics and cholinergic agonists. Always inform your doctor about all medicines you're taking.

What are common side effects of Donep-10 Tablet?

Common side effects include nausea, vomiting, diarrhoea, loss of appetite, muscle cramps, fatigue, and trouble sleeping. Consult your doctor if these persist or worsen.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Alkem House, Senapati Bapat Marg, Lower Parel, Mumbai Maharashtra- 400013

Country of origin: INDIA

References

HIGHLIGHTS OF PRESCRIBING INFORMATION. (2012). [Prescribing Information]. In ARICEPT Tablets and ARICEPT Orally Disintegrating Tablets (ODT). https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020690s035,021720s008,022568s005lbl.pdf
Kumar, A., Gupta, V., & Sharma, S. (2023, August 17). Donepezil. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK513257/
DailyMed - DONEPEZIL HYDROCHLORIDE- donepezil tablet, film coated. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e8ac5d36-8116-456f-8274-3defac54bb24
Donepezil: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00843
NCATS Inxight Drugs — DONEPEZIL HYDROCHLORIDE. (n.d.). https://drugs.ncats.io/drug/3O2T2PJ89D
Roux, F. J., & Kryger, M. H. (2010). Therapeutics for sleep-disordered breathing. Sleep Medicine Clinics, 5(4), 647–657. https://doi.org/10.1016/j.jsmc.2010.09.001

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