Dytor E 10 25 Mg Combi Kit Tablet 20

Dytor E 10 Combikit Tablet 20

Cipla Ltd.

Strip of 20 Units

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MRP ~~₹304.52~~

₹249.71

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Composition

Eplerenone (25 Mg) + Torsemide (10 Mg)

Dytor E 10 Tablet is primarily used for managing hypertension and oedema associated with congestive heart failure, liver cirrhosis, and chronic kidney disease. This medicine belongs to a combination formulation that includes an aldosterone antagonist and a loop diuretic.

In addition to its main uses, the medicine can also assist in achieving enhanced diuresis and anti-hypertensive effects. The dual action of this medication ensures that it provides more comprehensive relief than if either component was taken alone.

As with all medicines, it is essential to take this combi kit as directed by your doctor. Before you begin taking this medicine, be sure to tell your doctor about any pre-existing conditions or other medications you might be taking. If you notice any side effects while taking the medicine, alert your doctor right away. For optimal results, continue taking the medicine for as long as your doctor prescribes.

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Dytor E 10 Tablet is utilised for managing these conditions:

Hypertension, or high blood pressure
Fluid build-up and swelling, also known as oedema, due to heart failure
Edema associated with liver cirrhosis
Fluid retention in the body due to chronic kidney disease

Directions for Use of Dytor E 10 Combikit Tablet 20

To ensure the correct usage of Dytor E 10 Tablet, follow these steps:

Take the medicine orally as directed by your doctor.
Swallow each tablet whole with water. Avoid crushing or chewing them.
The medicine can be taken in the morning, with or without food as directed by your doctor.
Remember not to exceed the recommended dosage. If required, consult your doctor before adjusting the dose.

Dytor E 10 Tablet is taken orally.

Side Effects of Dytor E 10 Combikit Tablet 20

Dytor E 10 Tablet may have the following side effects:

Hypotension
Decrease in kidney function.
High levels of uric acid in the blood
Fatigue
Gastrointestinal disturbances

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Dytor E 10 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Hypotension: If Dytor E 10 Tablet causes low blood pressure, it might be helpful to take it before bedtime.
Gastrointestinal disturbances: If you experience nausea or upset stomach, try taking this medicine with meals.

How Dytor E 10 Combikit Tablet 20 Works?

Dytor E 10 Tablet is composed of two tablets:

Eplerenone (25 mg): This selective aldosterone receptor antagonist blocks the binding of aldosterone to mineralocorticoid receptors. By doing so, it helps reduce sodium reabsorption and increase water excretion by the kidneys. This leads to diuresis or increased urination and reduces blood pressure.
Torsemide (10 mg): As a high-ceiling loop diuretic, torsemide works by inhibiting the reabsorption of sodium, potassium, and chloride in certain parts of your kidneys—specifically in the ascending limb of the loop of Henle. This action results in increased excretion of water and electrolytes from your body.

Pregnancy

Dytor E 10 Tablet should be avoided during the second and third trimesters of pregnancy due to possible foetal toxicity. If you are pregnant or planning to conceive, discuss this with your doctor before starting this medicine.

Breastfeeding

If you are breastfeeding, please consult your doctor before starting this medicine.

Alcohol

Caution is advised while drinking alcohol when taking Dytor E 10 Tablet. This combination can lead to increased diuresis which might amplify the dehydrating effects of alcohol. It is best to consult your doctor on this.

Liver

Dytor E 10 Tablet should be avoided if you have severe liver diseases. For those with mild-to-moderate liver impairment, no initial dose adjustment is necessary but subsequent doses may need to be reduced. Discuss your liver health with your doctor before starting this medicine.

Kidney

The Dytor E 10 Tablet is contraindicated for patients with severe renal impairment and those who cannot urinate. If you have any kidney problems, it is a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

Some side effects of Dytor E 10 Tablet, such as dizziness and fatigue, might affect your ability to drive or operate machinery. Be cautious if these tasks are part of your daily routine.

Allergy

Dytor E 10 Tablet is not recommended if you are allergic to eplerenone, torsemide, or any other ingredients present in the medicine. Inform your doctor about any known allergies before starting this medication.

Children

Caution is advised when administering Dytor E 10 Tablet to individuals under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Dytor E 10 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised for patients above 70 years of age. Your doctor will guide you based on your health status.

Interactions of Dytor E 10 Combikit Tablet 20

Drug-Drug Interactions

Dytor E 10 Tablet interacts with the following medicines:

Strong CYP3A4 inhibitors: Medicines like ketoconazole, itraconazole, clarithromycin, and ritonavir can significantly increase the levels of eplerenone and increase the risk of high potassium levels in your blood (hyperkalaemia).
NSAIDs: When taken with Dytor E 10 Tablet, medicines like ibuprofen and naproxen can reduce the diuretic and blood pressure-lowering effects of torsemide.

Drug-Food Interactions

There are no specific food items known to interact with Dytor E 10 Tablet.

Drug-Disease Interactions

Dytor E 10 Tablet interacts with the following diseases:

Liver disease: Those with liver disease should exercise caution as Dytor E 10 Tablet could exacerbate their condition.
Diabetes: The Dytor E 10 Tablet could impact blood sugar control, so monitoring glucose levels closely when on this medication is essential.

Daily Dose

The daily dose of Dytor E 10 Tablet should be adhered to as advised by your doctor. Your dosage may vary depending on factors like your condition's severity and how you respond to the medicine. Ensure you adhere to the prescribed dosage and never exceed it without consulting your doctor.

Over Dose

If you happen to take more than the recommended dose of Dytor E 10 Tablet, you may experience side effects such as muscle cramps, weakness, or fatigue. In case of such symptoms, reach out to your doctor.

Missed Dose

In case you miss a dose of Dytor E 10 Tablet, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Do not increase the dosage without speaking to your doctor.

Store Dytor E 10 Tablet at a temperature not exceeding 30°C.
Keep the medicine away from direct light and moisture.
Make sure the container is tightly closed after use.
Keep this medicine out of the reach of children.

If you're taking Dytor E 10 Tablet for hypertension or heart-related conditions, limit your salt intake. Too much salt can raise your blood pressure and worsen your condition.
Regular physical activity can help manage congestive heart failure, liver cirrhosis, and chronic kidney disease, which Dytor E 10 Tablet helps manage. Consult your doctor about the type and amount of exercise that's right for you.

Fact Box

Drug Category	Aldosterone Antagonist, Loop Diuretic
Therapeutic Category	Antihypertensive, Diuretic
Available Dosage Types	Combi Kit
Habit Forming	No
Ailment	Hypertension, Heart Failure, Cirrhosis

What is Dytor E 10 Tablet used for?

Dytor E 10 Tablet is used to manage hypertension and oedema linked with congestive heart failure, liver cirrhosis, and chronic kidney disease.

How do the ingredients in Dytor E 10 Tablet work?

Eplerenone blocks aldosterone, reducing sodium absorption, while torsemide increases water and electrolyte excretion. Together they reduce blood pressure and relieve edema.

How should I take Dytor E 10 Tablet?

Take this medicine exactly as advised by your doctor.

Can I take Dytor E 10 Tablet if I have kidney or liver disease?

Patients with mild-to-moderate liver disease or renal impairment can take this medicine. However, it should be avoided in case of severe hepatic impairment.

Are there any side effects of Dytor E 10 Tablet?

Common side effects include renal impairment, muscle weakness, headaches and fatigue. Please consult your doctor if they persist.

Are there any precautions I need to take while using this medication?

Monitor your serum potassium levels and renal function periodically during treatment. If you have diabetes mellitus or gout, extra monitoring may be necessary.

Can I use other medications with Dytor E 10 Tablet?

Some medicines like strong CYP3A4 inhibitors may interact with Dytor E 10 Tablet. Always consult your doctor before starting or stopping any other medication while using this medicine.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: INDIA

References

Pfizer Inc. (2016). Highlights of prescribing information. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021437s013lbl.pdf
Eplerenone: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00700
Demadex. (n.d.). Demadex Tablets description and Clinical Pharmacology. In NDA 20136/S-023 (pp. 3–5). https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/020136s023lbl.pdf
Torasemide: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00214

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