Encorate 200 Mg Syrup 200 Ml

Encorate Solution 200ml

Sun Pharma Laboratories Ltd.

BOTTLE of 100 ML
BOTTLE of 200 ML

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MRP ~~₹145.6~~

₹119.39

₹0.73/ML

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Composition

Sodium Valproate / Valproic Acid (200 Mg)

Encorate Solution is primarily used to manage and prevent seizures, which includes epilepsy. It belongs to a class of medicines known as anti-epileptics.

This medicine is also effective against various types of seizures, including tonic-clonic, absence, partial, generalized, and myoclonic seizures. Moreover, it may be used to manage the manic phase of bipolar disorder and prevent migraine headaches.

The dosage and frequency of this medicine should be as directed by your doctor. It's important to tell your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you observe any side effects while using this medicine, inform your doctor immediately. For optimal results, continue taking this medicine for the duration prescribed by your doctor.

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Encorate Solution is used for managing the following health conditions:

Managing and preventing seizures, including tonic-clonic, absence, partial, generalized, and myoclonic seizures
Controlling the manic phase of bipolar disorder
Helping prevent migraine headaches

Directions for Use of Encorate Solution 200ml

Shake the bottle well before use.
Measure the exact quantity recommended by your doctor using a spoon or cup.
This medicine is typically taken two or more times daily, with or after food, to minimize stomach upset.
Do not exceed the prescribed dose without consulting your doctor.
Remember to always follow your doctor's instructions carefully when taking this medication.

Encorate Solution is taken orally.

Encorate Solution may have the following common side effects:

Nausea
Vomiting
Dizziness
Headache
Drowsiness
Tremor: This term refers to an involuntary, rhythmic muscle contraction leading to shaking movements in one or more parts of your body.
Weight gain

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Encorate Solution. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some suggestions for managing common side effects:

Nausea: Try taking Encorate Solution with food or milk.
Dizziness: If you feel dizzy after taking this medicine, consider taking it at bedtime.

Encorate Solution contains sodium valproate (200 mg), and its activity in the body can be described as follows:

Increases GABA Levels: Sodium valproate increases the levels of a neurotransmitter called gamma-aminobutyric acid (GABA) in your brain. GABA helps calm and stabilise brain activity, thus preventing seizures and regulating mood.
Blocks Sodium and Calcium Channels: Apart from increasing GABA levels, sodium valproate also blocks voltage-gated sodium channels and T-type calcium channels. This contributes to its anti-epileptic effects.

Pregnancy

Encorate Solution is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Caution is advised while taking Encorate Solution if you are breastfeeding. It is best to consult your doctor to understand the potential risks and benefits.

Alcohol

Drinking alcohol while taking Encorate Solution may increase some side effects, such as dizziness and drowsiness. It's advisable to limit or avoid alcohol consumption during medication.

Liver

Caution is advised while taking Encorate Solution in case of liver impairment. This medicine may affect liver function, so it's important to discuss any liver problems with your doctor before starting this medicine.

Kidney

If you have a history of kidney issues, it's a good idea to consult your doctor before taking Encorate Solution. They will evaluate if this medicine is suitable for you.

Using Machines & Driving

Encorate Solution may cause dizziness or drowsiness. If you experience these effects, avoid driving or operating heavy machinery until you feel capable again.

Allergy

If you're allergic to sodium valproate or any other ingredients in Encorate Solution, avoid using this medicine. Always let your doctor know about any allergies before starting a new medication.

Children

It's important to consult your doctor before giving Encorate Solution to children under 18 years of age.

Older Patients

Older patients should take Encorate Solution under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Encorate Solution interacts with the following medicines:

Anti-epileptic medications: When used alongside Encorate Solution, other anti-epileptic medicines such as phenytoin and carbamazepine may alter its effectiveness or increase the risk of side effects.
Anticoagulants: Medicines like warfarin can interact with Encorate Solution, potentially altering their effectiveness or increasing the risk of bleeding.
Benzodiazepines: Medicines like diazepam may interact with Encorate Solution, potentially leading to an increase in drowsiness or sedation.
Antidepressants: When taken with Encorate Solution, antidepressants like amitriptyline and nortriptyline can have altered effects or increased risk of side effects.
Carbapenem antibiotics: Antibiotics such as meropenem and imipenem can reduce the efficacy of Encorate Solution.

Drug-Food Interactions

Drug-Disease Interactions

Encorate Solution interacts with the following diseases:

Liver disease: Patients with liver disease should be cautious as Encorate Solution could exacerbate their condition.
Pancreatic disorders: People with pancreatic disorders should use Encorate Solution carefully as it may increase the risk of pancreatitis.
Bleeding disorders: Patients with bleeding disorders should use this medication cautiously as it might interfere with blood clotting time.
Urea cycle disorders: Individuals suffering from urea cycle disorders need to be cautious while using Encorate Solution due to the potential for increased ammonia levels.

Daily Dose

The daily dose of Encorate Solution should be taken exactly as prescribed by your doctor. This dosage may vary depending on individual factors, such as the severity of your condition and how you respond to treatment. Never exceed the prescribed dosage without consulting your doctor.

Over Dose

In case of an accidental overdose of Encorate Solution, you might experience symptoms like drowsiness, dizziness, or an upset stomach. If these symptoms persist or worsen, it's important to inform your doctor.

Missed Dose

If you forget to take Encorate Solution as per schedule, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never double up on doses without consulting your doctor.

Store Encorate Solution inside a tightly closed container at room temperature, ideally below 30°C.
The solution should be kept away from light and moisture.
Always keep Encorate Solution out of the reach of children.
Make sure to use this medicine before the expiry date on the container.

If you're managing epilepsy with Encorate Solution, aim to follow a balanced diet rich in fruits, vegetables and whole grains. It's believed that such a diet may help improve brain health.
Regular physical activity can enhance your overall well-being and contribute towards better management of seizures. However, you should consult your doctor for a safe and suitable exercise regimen.

Fact Box

Drug Category	Neurotransmitter Modulator
Therapeutic Category	Anti-epileptic
Available Dosage Types	Solution
Habit Forming	No
Ailment	Epilepsy, Bipolar Disorder, Migraine

What is Encorate Solution used for?

Encorate Solution is primarily used to manage different types of seizures, including tonic-clonic, absence, partial, generalised, and myoclonic seizures. It can also help with managing the manic phase of bipolar disorder and preventing migraine headaches.

How does Encorate Solution work?

The active ingredient in Encorate Solution, sodium valproate, works by increasing the levels of a neurotransmitter called gamma-aminobutyric acid (GABA) in the brain. This helps calm and stabilise brain activity, prevent seizures, and regulate mood.

How should I take Encorate Solution?

Encorate Solution should be taken orally with or after food to minimise stomach upset. Always shake the syrup well before use and measure accurately using the provided cup or syringe.

What are some common side effects of Encorate Solution?

Common side effects include nausea, vomiting, dizziness, headache, drowsiness, weakness, tremor, and weight gain. These effects are usually mild and temporary. Consult your doctor if they persist.

Are there any precautions I should know about?

Encorate Solution should be used with caution in patients with liver disease, pancreatic disorders, bleeding disorders, and urea cycle disorders. Pregnant women should avoid using this medication as it may cause birth defects.

Can Encorate Solution interact with other medicines?

Yes. Sodium valproate can interact with several medications, including other anti-epileptic medicines, aspirin and other salicylates, anticoagulants, benzodiazepines, antidepressants, antipsychotics and carbapenem antibiotics.

What should I do in case of an overdose?

Symptoms of sodium valproate overdose include deep coma, low blood pressure or respiratory depression. If you suspect an overdose, seek immediate medical attention.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

SUN HOUSE CTS No. 201, 201, Western Express Hwy, Ram Nagar, Goregaon, Mumbai, Maharashtra 400063

Country of origin: INDIA

References

HIGHLIGHTS OF PRESCRIBING INFORMATION. (2013). https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/020593s026lbl.pdf
HIGHLIGHTS OF PRESCRIBING INFORMATION. (n.d.). http://editor.fresenius-kabi.us/PIs/US-PH-Valproate-Sodium-Inj-FK-45982G-10-2015-PI.pdf
DailyMed - DIVALPROEX SODIUM tablet, delayed release. (2024). Nih.gov. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ea85f517-4773-4688-88b6-5612612330f6
Information on Sodium Valproate. (2024). Sanofi.com. https://www.sanofi.com/en/our-company/social-impact/responsible-business-values/sodium-valproate

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