Espin At 5025 Mg Tablet 10

Espin At Tablet 10

Q: What is Espin-AT Tablet used for?

Espin-AT Tablet is used to manage hypertension (high blood pressure) and angina pectoris (chest pain).

Q: How does Espin-AT Tablet work?

This medicine combines atenolol and S-amlodipine, reducing blood pressure by slowing the heart rate and relaxing arterial smooth muscle.

Q: Can I take Espin-AT Tablet without food?

Yes, you can take this medicine with or without food. Consistency in timing is recommended.

Q: What should I do if I experience side effects like dizziness or swollen ankles?

To manage these side effects, try rising slowly from a sitting position and elevate your legs periodically. Consult your doctor if symptoms persist.

Q: Can I suddenly stop taking Espin-AT Tablet?

No, sudden discontinuation may worsen angina. Always consult your doctor before stopping this medication.

Q: Is Espin-AT Tablet safe during pregnancy or lactation?

No, this medicine is not recommended for use during pregnancy or lactation. Always consult your doctor before starting any new medication.

Q: Can Espin-AT Tablet interact with other medicines?

Yes, it can interact with other antihypertensive agents, diuretics, NSAIDs and some other medicines. Discuss all medications you're taking with your doctor.

Intas Pharmaceuticals Ltd

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Composition

Atenolol (50 Mg) + S-amlodipine (2.5 Mg)

Espin-AT Tablet is primarily used to manage high blood pressure or hypertension. This medicine is a combination medication and belongs to the group of antihypertensive agents.

Apart from its key use in managing hypertension, Espin-AT Tablet can also be utilised to manage angina pectoris, a condition characterised by chest pain. This dual functionality makes it a valuable medicine for patients dealing with these cardiovascular conditions.

Before you start taking this medicine, it's crucial to consult your doctor who will guide you on the appropriate dosage and frequency. Make sure you inform your doctor about any preexisting conditions or ongoing medications. If you notice any side effects while on this medication, notify your doctor immediately. Continue taking Espin-AT Tablet for the duration prescribed by your doctor for optimal results.

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Espin-AT Tablet is used for the following medical conditions:

Lowering high blood pressure, also known as hypertension
Decreasing the risk of serious cardiovascular events, such as strokes and heart attacks
Helping in the management of chest pain, a condition known as angina pectoris.

These uses are based on the combined effects of the two active ingredients in this medicine – atenolol and S-amlodipine. These components work together to reduce blood pressure and ease the workload on your heart.

Directions for Use of Espin At Tablet 10

Follow these instructions while taking Espin-AT Tablet:

Swallow the tablet whole with a glass of water.
You can take this medicine with or without food.
It's important not to stop taking this medicine without consulting your doctor first.
Avoid crushing or chewing the tablet.
Try to take your dose at the same time each day for maximum effectiveness.

Remember, these are general guidelines. Always follow your doctor's specific advice regarding how to use this medicine.

Espin-AT Tablet is taken orally.

While using Espin-AT Tablet, you may experience the following side effects:

Fatigue: This refers to a feeling of tiredness or lack of energy.
Bradycardia: This is a medical term for a slower than normal heart rate.
Edema: This condition leads to swelling in your ankles or feet due to fluid buildup.
Dizziness
Headache
Gastrointestinal disturbances, which may include symptoms such as nausea, diarrhoea or constipation.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Espin-AT Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here's how you can manage some common side effects:

Fatigue: If this medicine makes you feel tired, consider taking it at bedtime.
Gastrointestinal disturbances: To minimise these symptoms, try taking Espin-AT Tablet with your meals.

Espin-AT Tablet contains two active ingredients that work together to lower blood pressure:

S(-)Amlodipine (2.5 mg): As a dihydropyridine calcium channel blocker, S-amlodipine lowers blood pressure by relaxing arterial smooth muscle which causes your blood vessels to widen or dilate, leading to reduced peripheral vascular resistance. This mechanism improves blood flow and oxygen delivery to the heart and reduces the burden on your heart.
Atenolol (50 mg): This component acts as a selective beta-1-adrenergic receptor blocker. It reduces the workload on your heart and lowers blood pressure by slowing down your heart rate, reducing the strength of heart muscle contractions, suppressing renin release from your kidneys which in turn decreases angiotensin II formation and aldosterone secretion, and reduces the outflow of certain nervous signals from your brain.

Pregnancy

Espin-AT Tablet is contraindicated during pregnancy. If you are pregnant or planning to conceive, discuss this with your doctor before starting this medicine.

Breastfeeding

Espin-AT Tablet is contraindicated for breastfeeding women. Consult your doctor to understand the potential risks and benefits.

Alcohol

While taking Espin-AT Tablet, it's advised to limit alcohol consumption as it may increase the risk of adverse effects such as dizziness and fainting.

Liver

Caution is advised while taking Espin-AT Tablet if you have mild to moderate liver impairment. This medicine may affect liver function. It's not recommended if you have severe liver diseases.

Kidney

This medicine is cleared by the kidneys, so caution is advised if you have a history of kidney problems. Consult your doctor before taking Espin-AT Tablet, especially if your kidney function is impaired.

Using Machines & Driving

Since Espin-AT Tablet may cause dizziness, caution is advised while driving or operating heavy machinery until you know how this medicine affects you.

Allergy

Avoid using Espin-AT Tablet if you are allergic to atenolol, S-amlodipine, or any other ingredients in this medicine. Symptoms of an allergic reaction may include rash, itching, difficulty breathing or swelling of the face, lips or throat.

Children

Espin-AT Tablet should not be given to children under 18 years of age without medical supervision. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Espin-AT Tablet under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Espin-AT Tablet interacts with the following medicines:

Antihypertensive Agents: Medicines such as lisinopril or losartan may interact with Espin-AT Tablet, potentially increasing the risk of low blood pressure, also known as hypotension.
Diuretics: When taken together with Espin-AT Tablet, diuretics like chlorthalidone may increase your blood sugar levels.
Antipsychotics: Medicines like chlorpromazine may interact with Espin-AT Tablet, potentially increasing atenolol levels in your body.
Non-steroidal anti-inflammatory drugs (NSAIDs): NSAIDs like ibuprofen may reduce the blood pressure-lowering effect of Espin-AT Tablet.
CYP3A4 Inhibitors: Medicines such as itraconazole and ritonavir can increase the level of S-amlodipine in your body.
CYP3A4 Inducers: Certain medications like rifampicin can decrease the level of S-amlodipine in your body.

Drug-Food Interactions

Espin-AT Tablet interacts with certain foods. You should avoid consuming grapefruit or its juice while taking this medication as it can increase the level of Samlodipine in your body, leading to increased side effects.

Drug-Disease Interactions

Espin-AT Tablet interacts with the following diseases:

Liver Disease: Patients with severe liver impairment should use caution when taking Espin-AT Tablet as atenolol may accumulate due to decreased liver clearance.
Kidney Disease: If you have impaired kidney function, dose adjustment may be required as atenolol is primarily eliminated by the kidneys.
Diabetes: Espin-AT Tablet could impact blood sugar control requiring you to monitor glucose levels closely.
Hyperthyroidism: Atenolol may mask the signs of developing hyperthyroidism, such as a fast heart rate. Abrupt withdrawal may intensify symptoms of hyperthyroidism or trigger a thyroid storm a severe and potentially lifethreatening form of thyrotoxicosis (excessive thyroid hormone in the body).
Heart Diseases: Patients with conditions like cardiogenic shock, second or thirddegree heart block, severe bradycardia (resting heart rate < 45 to 50 bpm), and decompensated heart failure should avoid using Espin-AT Tablet.

Daily Dose

The daily dose of Espin-AT Tablet should be taken as directed by your doctor. Your dosage may vary based on factors such as your condition's severity and your response to the medicine. Always follow your doctor's prescribed dosage and avoid exceeding it without his or her consultation.

Over Dose

Overdosing on Espin-AT Tablet may result in symptoms such as fatigue, dizziness, and slow heart rate. If you suspect you've taken more than the prescribed dosage, consult your doctor for advice.

Missed Dose

If you forget a dose of Espin-AT Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Don't increase your dose without speaking to your doctor.

Store Espin-AT Tablet below 30°C to maintain its effectiveness.
Keep it in a dry place, away from moisture.
Avoid exposing the medicine to direct sunlight or extreme heat.
Always keep this medicine out of reach and sight of children.
Check the pack for the expiry date and use the medicine before that.

Reducing your intake of salt can help control high blood pressure, one condition that Espin-AT Tablet is used to manage. Consider using herbs or spices for flavour instead of salt.
Regular moderate exercise, such as brisk walking or cycling, can help lower your blood pressure and keep your heart healthy. Be sure to consult your doctor before starting any new exercise regimen.

Fact Box

Drug Category	Beta 1 Blocker, Calcium Channel Blocker
Therapeutic Category	Antihypertensive
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypertension, Angina Pectoris

What is Espin-AT Tablet used for?

Espin-AT Tablet is used to manage hypertension (high blood pressure) and angina pectoris (chest pain).

How does Espin-AT Tablet work?

This medicine combines atenolol and S-amlodipine, reducing blood pressure by slowing the heart rate and relaxing arterial smooth muscle.

Can I take Espin-AT Tablet without food?

Yes, you can take this medicine with or without food. Consistency in timing is recommended.

What should I do if I experience side effects like dizziness or swollen ankles?

To manage these side effects, try rising slowly from a sitting position and elevate your legs periodically. Consult your doctor if symptoms persist.

Can I suddenly stop taking Espin-AT Tablet?

No, sudden discontinuation may worsen angina. Always consult your doctor before stopping this medication.

Is Espin-AT Tablet safe during pregnancy or lactation?

No, this medicine is not recommended for use during pregnancy or lactation. Always consult your doctor before starting any new medication.

Can Espin-AT Tablet interact with other medicines?

Yes, it can interact with other antihypertensive agents, diuretics, NSAIDs and some other medicines. Discuss all medications you're taking with your doctor.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

Corporate House, Near Sola Bridge, S. G. Highway, Thaltej, Ahmedabad 380054, Gujarat, India

Country of origin: INDIA

References

U.S. Food and Drug Administration. (2012). Atenolol Tablets USP. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/018240s032lbl.pdf
U.S. Food and Drug Administration. (2019). New Drug Application 212895Orig1s000. https://www.accessdata.fda.gov/drugsatfda_docs/nda/2019/212895Orig1s000OtherR.pdf
Şen, S., Demir, M., Yiğit, Z., & Üresin, A. Y. (2018). Efficacy and Safety of S-Amlodipine 2.5 and 5 mg/d in Hypertensive Patients Who Were Treatment-Naive or Previously Received Antihypertensive Monotherapy. Journal of Cardiovascular Pharmacology and Therapeutics, 23(4), 318–328. https://doi.org/10.1177/1074248418769054

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