Flucalup 50 Mg Tablet 4

Flucalup 50 Dt Tablet 4

Lupin Ltd

Strip of 4 Units

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MRP ~~₹38.65~~

₹19.29

₹9.66/Units

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Composition

Fluconazole (50 Mg)

Flucalup 50 Dt Tablet 4 is primarily used to manage fungal infections. It belongs to a group of medicines known as triazole antifungals, which are effective against a range of fungal conditions.

It is also used in managing oropharyngeal and esophageal candidiasis, vaginal yeast infections, and the prevention of fungal infections in patients with compromised immunity.

Before starting this medicine, do inform your doctor about any pre-existing health conditions and other medications you are taking. If you experience any side effects while taking this medicine, immediately inform your doctor. For the best outcome, ensure that you continue the medication for the prescribed duration.

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Flucalup 50 Dt Tablet 4 is used for:

Managing oropharyngeal candidiasis
Controlling esophageal candidiasis
Combating vaginal candidiasis
Preventing fungal infections in immunocompromised patients

Directions for Use of Flucalup 50 Dt Tablet 4

Here's how to take Flucalup 50 Dt Tablet 4:

Dissolve the tablet in a glass of water before taking it.
Do not chew the tablet.
It can be taken with or without food.
Do not exceed the dosage recommended by your doctor.

Flucalup 50 Dt Tablet 4 is taken orally.

Flucalup 50 Dt Tablet 4 may cause the following common side effects:

Nausea
Vomiting
Abdominal pain
Diarrhoea
Rash
Tiredness

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Flucalup 50 Dt Tablet 4. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips to manage common side effects:

Diarrhoea: If you experience this side effect, keep yourself hydrated and replenish your electrolytes frequently.
Nausea: Taking this medicine after meals can help manage this symptom.

Flucalup 50 Dt Tablet 4 contains fluconazole (50 mg), and its mechanism of action is as follows:

Inhibition of cytochrome P450 enzyme: Fluconazole works by inhibiting a specific enzyme in fungi known as cytochrome P450 14α-demethylase. This enzyme plays a crucial role in the conversion of lanosterol into ergosterol.
Disruption of fungal cell membrane: By inhibiting the production of ergosterol, a vital component of the fungal cell membrane, fluconazole causes an increase in membrane permeability. This results in leakage of cellular contents, leading to fungal cell death and thus halting the growth and spread of the fungal infection.

Pregnancy

Flucalup 50 Dt Tablet 4 should be used with caution if you are pregnant. It is beneficial to discuss with your doctor before taking this medicine.

Breastfeeding

Flucalup 50 Dt Tablet 4 may pass into breast milk, hence, caution is advised if you are breastfeeding. Always consult your doctor about the potential risks and benefits.

Alcohol

Caution is advised on the use of alcohol with Flucalup 50 Dt Tablet 4. It is always recommended to consult your doctor beforehand for any concerns.

Liver

Fluconazole, the active ingredient in Flucalup 50 Dt Tablet 4, is extensively processed in the liver. If you have liver disease, it is important to discuss this with your doctor before starting this medicine.

Kidney

Flucalup 50 Dt Tablet 4 does not require dosage adjustments for mild to moderate kidney issues. However, for severe renal dysfunction, the dose should be reduced. Consult your doctor for personalised advice if you have kidney problems.

Using Machines & Driving

No specific precautions are needed while using machines or driving after taking Flucalup 50 Dt Tablet 4. However, if you experience dizziness or any other side effects that affect your ability to concentrate, avoid such activities and consult your doctor.

Allergy

Flucalup 50 Dt Tablet 4 is contraindicated if you are allergic to fluconazole, any azole antifungals, or any component of the tablet formulation. If you experience any allergic reactions, seek medical attention immediately.

Children

Flucalup 50 Dt Tablet 4 is typically prescribed for adults. Caution is advised when considering this medicine for use in children under 18 years of age.

Older Patients

For elderly patients with liver or kidney issues, it is advisable to consult your doctor before starting this medicine. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Flucalup 50 Dt Tablet 4 interacts with the following medicines:

Sulfonylureas: Flucalup 50 Dt Tablet 4 can increase levels of sulfonylureas such as chlorpropamide, glibenclamide, glipizide, and tolbutamide, leading to low blood sugar (hypoglycaemia).
Antiepileptics: Medications like carbamazepine and lamotrigine can boost levels of phenytoin in your body, raising the risk of toxicity.
Bronchodilators: Medications like salbutamol and salmeterol can enhance theophylline concentrations, which may increase side effects.
Anticoagulants: Flucalup 50 Dt Tablet 4 can intensify the anticoagulant effect of medications like apixaban and warfarin, increasing the risk of bleeding.
Sedatives: It can increase levels of benzodiazepines like midazolam and opioids like morphine, causing excessive sedation.

Drug-Food Interactions

There are no known interactions between Flucalup 50 Dt Tablet 4 and any specific foods or beverages.

Drug-Disease Interactions

Flucalup 50 Dt Tablet 4 interacts with the following diseases:

Liver disease: Patients with liver disease should be cautious because fluconazole is extensively metabolised by the liver, which could potentially worsen their condition.
Prolonged QT interval: Those with a prolonged QT interval should avoid this medicine due to additive effects.

Daily Dose

Your doctor will provide guidance on the daily dosage of Flucalup 50 Dt Tablet 4 based on your individual needs, including the severity of your condition and your response to treatment. Always follow the prescribed dosage and consult your doctor before making any changes.

Over Dose

If you accidentally take more Flucalup 50 Dt Tablet 4 than recommended, immediately inform your doctor or reach out to the nearest hospital.

Missed Dose

If you forget to take your Flucalup 50 Dt Tablet 4, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and resume your regular schedule. Do not increase your dosage without consulting your doctor.

Store Flucalup 50 Dt Tablet 4 below 30°C.
Keep it in a tightly closed container.
Avoid exposure to light and moisture.
Keep the medicine away from children's reach.
Always check the expiry date before use.

If you are taking Flucalup 50 Dt Tablet 4 for fungal infections, maintain good personal hygiene to prevent spreading the fungus to other body parts or to other people. For example, wash your hands often, especially before eating or preparing food.
Include probiotics like yoghurt in your diet. They can help maintain a healthy balance of bacteria and yeast in your body, which may help prevent fungal infections.

Fact Box

Drug Category	Fungal Cytochrome P450 Inhibitor
Therapeutic Category	Triazole antifungals
Available Dosage Types	Antifungal
Habit Forming	No
Ailment	Oropharyngeal Candidiasis, Esophageal Candidiasis, Vaginal Candidiasis

What is Flucalup 50 Dt Tablet 4 used for?

Flucalup 50 Dt Tablet 4 is mainly used to manage fungal infections, such as thrush in the mouth and throat, vaginal yeast infections, and to prevent fungal infections in people with a weakened immune system.

How does Flucalup 50 Dt Tablet 4 work against fungi?

Flucalup 50 Dt Tablet 4 works by blocking an enzyme in the fungi, which prevents them from making a substance called ergosterol. This breaks down the cell membrane of the fungi, causing them to die.

Can I take Flucalup 50 Dt Tablet 4 if I have difficulty swallowing tablets?

Yes, Flucalup 50 Dt Tablet 4 is a dispersible tablet that can be dissolved in a small amount of water and then ingested.

Can I experience side effects when taking Flucalup 50 Dt Tablet 4?

A few people might experience common side effects of Flucalup 50 Dt Tablet 4 like nausea, vomiting, abdominal pain, diarrhoea, and rash. If you experience severe reactions or have the effects for a prolonged duration, consult your doctor immediately.

Are there any precautions I need to take when using Flucalup 50 Dt Tablet 4?

If you are pregnant, breastfeeding, or have liver, kidney, or heart disease, you should use Flucalup 50 Dt Tablet 4 with caution. Always inform your doctor about any pre-existing conditions that you may have.

What should I do if I'm allergic to this medicine?

If you're allergic to fluconazole or any azole antifungals, you should not take Flucalup 50 Dt Tablet 4. Consult your doctor for alternative medications.

Can Flucalup 50 Dt Tablet 4 interact with other medicines?

Yes, Flucalup 50 Dt Tablet 4 can interact with various medications, affecting their efficacy and safety. It’s important to inform your doctor if you are taking sulfonylureas (such as glibenclamide), antiepileptics (like carbamazepine), bronchodilators (such as salbutamol), anticoagulants (like warfarin), or sedatives (such as benzodiazepines).

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Divya Chauhan

Medical Writer & Reviewer | 6 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

Kalpataru Inspire, 3rd Floor, Off. Western Express Highway, Santacruz (East), Mumbai

Country of origin: INDIA

References

Fluconazole: A medicine to treat fungal infections. (2023, March 10) https://www.nhs.uk/medicines/fluconazole/
Fluconazole: MedlinePlus drug information. (n.d.). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a690002.html
Govindarajan A, Bistas KG, Ingold CJ, et al. Fluconazole. (2024, February 28). In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK537158/
Fluconazole (marketed as Diflucan) information. (2015, July 10). U.S. Food and Drug Administration. https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/fluconazole-marketed-diflucan-information
Fluconazole 50 mg capsules - Summary of product characteristics (SmPC) - (emc). (n.d.). Electronic Medicines Compendium (emc). https://www.medicines.org.uk/emc/product/4437/smpc#gref

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