Gibtulio Met 1251000 Mg Tablet 10

Gibtulio Met 12.5mg/1000mg Tablet 10

Lupin Ltd

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Composition

Empagliflozin (12.5 Mg) + Metformin (1000 Mg)

Gibtulio Met 12.5mg/1000mg Tablet is used to manage type 2 diabetes mellitus. This medicine is a combination of two active ingredients, both of which belong to a group of medicines known as antihyperglycemic agents.

In addition to its primary use in managing blood sugar levels in adults with type 2 diabetes, this medicine also carries cardiovascular benefits. It may help reduce the risk of hospitalisation due to heart failure in patients with established cardiovascular disease and type 2 diabetes.

This medicine should be taken orally as directed by your doctor. Before you start taking it, inform your doctor about any pre-existing conditions or ongoing medications. If you notice any side effects while on this medicine, notify your doctor immediately. For the best results, continue taking the medicine for the duration prescribed by your doctor.

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Uses of Gibtulio Met 12.5mg/1000mg Tablet 10

Gibtulio Met 12.5mg/1000mg Tablet aids in the following:

Enhancing blood sugar control in adults diagnosed with type 2 diabetes mellitus
Complementing dietary changes and regular exercise for effective diabetes management
Reducing the risk of hospitalisation due to heart failure in type 2 diabetes patients with existing cardiovascular disease

Directions for Use of Gibtulio Met 12.5mg/1000mg Tablet 10

Take Gibtulio Met 12.5mg/1000mg Tablet in the following manner:

Always swallow the tablet whole with water.
Avoid crushing, chewing, splitting or dissolving the tablet.
Ensure that you take the medicine with meals to minimise potential digestive side effects.
If you're unsure about any aspect of using this medicine, consult your doctor for guidance.

Gibtulio Met 12.5mg/1000mg Tablet is taken orally.

Side Effects of Gibtulio Met 12.5mg/1000mg Tablet 10

Gibtulio Met 12.5mg/1000mg Tablet may have the following common side effects:

Urinary tract infection
Female genital mycotic infections: These are yeast infections in the female genital area.
Nasopharyngitis: This is inflammation of the nose and throat, commonly known as a cold.
Headache
Diarrhoea
Nausea
Vomiting
Abdominal discomfort
Indigestion
Asthenia: This means you might feel weak or lack energy.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Gibtulio Met 12.5mg/1000mg Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Try taking Gibtulio Met 12.5mg/1000mg Tablet with food or milk.
Indigestion: If you have indigestion, take this medicine after meals to lessen this effect.

How Gibtulio Met 12.5mg/1000mg Tablet 10 Works?

Gibtulio Met 12.5mg/1000mg Tablet contains two active ingredients:

Empagliflozin (12.5 mg): This ingredient is a sodium-glucose co-transporter 2 (SGLT2) inhibitor. In simple terms, it works by blocking the reabsorption of glucose (sugar) by the kidneys. This leads to the excretion of excess glucose through urine and ultimately lowers blood glucose levels. Importantly, this process does not depend on insulin.
Metformin (1000 mg): This ingredient is a biguanide antihyperglycemic agent. It acts in three ways: It reduces the production of glucose in the liver, decreases the absorption of glucose in the intestines, and improves insulin sensitivity by aiding peripheral glucose uptake and utilisation. Unlike certain other diabetes medicines, it does not cause hypoglycemia (low blood sugar) in patients with type 2 diabetes or in people without diabetes, except in rare circumstances.

Pregnancy

Care is advised if you are pregnant while taking Gibtulio Met 12.5mg/1000mg Tablet. The pros and cons should be discussed with your doctor before starting the medicine.

Breastfeeding

Metformin, one component of Gibtulio Met 12.5mg/1000mg Tablet, is found in low levels in human milk. It's crucial to decide whether to discontinue breastfeeding or stop the medicine after discussing it with your doctor.

Alcohol

Excessive alcohol intake while on Gibtulio Met 12.5mg/1000mg Tablet can heighten the risk of lactic acidosis, a serious condition. It's advisable to limit alcohol consumption.

Liver

People with liver problems should use Gibtulio Met 12.5mg/1000mg Tablet with caution as it can affect liver function. Discuss this with your doctor before starting this medicine.

Kidney

Discuss this with your doctor before starting this medicine if you are suffering from any kidney issues.

Using Machines & Driving

No specific warnings exist about driving or operating machinery after taking Gibtulio Met 12.5mg/1000mg Tablet. However, if you feel unwell or experience any side effects, avoid such activities until you feel better.

Allergy

Gibtulio Met 12.5mg/1000mg Tablet is contraindicated if you have had a serious hypersensitivity reaction to empagliflozin or metformin, or any other ingredients in the tablet.

Children

The safety and effectiveness of Gibtulio Met 12.5mg/1000mg Tablet have not been established in children. Always consult a doctor before giving this medicine to anyone under 18 years of age.

Older Patients

Elderly patients may be more susceptible to side effects of Gibtulio Met 12.5mg/1000mg Tablet and should therefore use the medicine under medical supervision. Regular renal function assessments are recommended as the risk of metformin accumulation and lactic acidosis increases with age.

Interactions of Gibtulio Met 12.5mg/1000mg Tablet 10

Drug-Drug Interactions

Gibtulio Met 12.5mg/1000mg Tablet interacts with the following medicines:

Carbonic anhydrase inhibitors: Medicines like acetazolamide and dorzolamide can increase the risk of lactic acidosis when taken with Gibtulio Met 12.5mg/1000mg Tablet. Regular health check-ups may be needed.
Medicines that reduce metformin clearance: Medicines like ranolazine, vandetanib, dolutegravir, and cimetidine could lead to the accumulation of metformin if used concurrently with Gibtulio Met 12.5mg/1000mg Tablet. This may require careful consideration of benefits and risks.
Insulin or insulin secretagogues: If you're also taking medicines like glimepiride, gliclazide or insulin, you might need a lower dose to minimise the risk of hypoglycaemia.
Diuretics: Taking furosemide, hydrochlorothiazide or other diuretics along with Gibtulio Met 12.5mg/1000mg Tablet might intensify the diuretic effect. This could potentially cause dehydration.

Drug-Food Interactions

Gibtulio Met 12.5mg/1000mg Tablet doesn't have any significant interactions with specific foods.

Drug-Disease Interactions

Gibtulio Met 12.5mg/1000mg Tablet interacts with the following diseases:

Renal impairment: If you have severe kidney problems or end-stage renal disease, you should avoid taking this medicine due to the increased risk of lactic acidosis.
Acidosis: If you have metabolic acidosis, including diabetic ketoacidosis, this medicine is not recommended for use.
Hypotension: For those with low blood pressure or taking medicines for it, this tablet may cause further reduction in blood pressure. Regular monitoring may be needed.
Hypoglycemia: If you're prone to low blood sugar or take other antidiabetic medicines, careful dosage adjustment might be required to prevent hypoglycaemia.
Liver disease: Patients with liver disease should exercise caution while taking this medication as it could potentially worsen their condition.

Dosage of Gibtulio Met 12.5mg/1000mg Tablet 10

Daily Dose

You should take the Gibtulio Met 12.5mg/1000mg Tablet as prescribed by your doctor. The dosage can vary depending on factors like your condition's severity and how you respond to the medication. Always follow your doctor's instructions and never change the prescribed dosage without consulting them first.

Over Dose

If an overdose occurs, common symptoms include nausea, diarrhoea, and abdominal discomfort. In such cases, inform your doctor without delay. Do not panic; your doctor will guide you on the necessary steps to take.

Missed Dose

If you forget to take a dose of Gibtulio Met 12.5mg/1000mg Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.

Store your Gibtulio Met 12.5mg/1000mg Tablet at room temperature, ideally below 30°C.
Avoid exposure to extreme heat or cold.
Keep the container tightly closed to protect the medicine from moisture and light.
Always keep this medicine out of reach and sight of children.
Ensure you use the medicine before its expiry date.

Follow a balanced diet with low sugar intake: Consuming too much sugar can worsen your type 2 diabetes, which Gibtulio Met 12.5mg/1000mg Tablet is designed to help manage. Opt for whole grains, fruits and vegetables instead of sugary snacks or drinks.
Stay active: Regular physical activity can increase insulin sensitivity and help control blood sugar levels. Aim for at least 30 minutes of moderate exercise, like brisk walking or cycling, every day. Always consult your doctor before starting any new exercise regimen.

Fact Box

Drug Category	SGLT2 Inhibitor, Biguanide
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 diabetes

Can Gibtulio Met 12.5mg/1000mg Tablet be used to manage type 1 diabetes?

No, Gibtulio Met 12.5mg/1000mg Tablet is not for managing type 1 diabetes, it's only indicated for type 2 diabetes.

Is it okay to crush or chew the Gibtulio Met 12.5mg/1000mg Tablet?

No, the tablet should be swallowed whole. Crushing or chewing can disrupt its effectiveness.

What should I do if I forget to take a dose of Gibtulio Met 12.5mg/1000mg Tablet?

As soon as you remember, take the missed dose. But if it's nearly time for the next dose, skip the missed one.

If my blood sugar levels improve, can I stop taking Gibtulio Met 12.5mg/1000mg Tablet?

How long does it generally take for Gibtulio Met 12.5mg/1000mg Tablet to start working?

Typically, you may see improvements in blood sugar levels within 2 weeks of starting the medicine.

Can I drink alcohol while taking Gibtulio Met 12.5mg/1000mg Tablet?

Alcohol may increase the risk of lactic acidosis with this medication, so excessive alcohol intake should be avoided.

Can pregnant or breastfeeding women take Gibtulio Met 12.5mg/1000mg Tablet?

If you're pregnant or breastfeeding, consult your doctor before starting this medication due to potential risks.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Kalpataru Inspire, 3rd Floor, Off. Western Express Highway, Santacruz (East), Mumbai

Country of origin: GERMANY

References

Empagliflozin: MedlinePlus Drug Information. (n.d.). https://medlineplus.gov/druginfo/meds/a614043.html
Empagliflozin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB09038
Metformin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00331
DailyMed - METFORMIN ER 500 MG tablet METFORMIN ER 750 MG tablet. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b857eccf-b9ff-45ba-8241-f47f5caada2a
Metformin: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a696005.html

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