Gliclize 30 Tablet Mr 10

Gliclize 30 Mr Tablet 10

John Lee

Strip of 10 Units

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MRP ~~₹64.62~~

₹32.25

₹6.46/Units

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Composition

Gliclazide (30 Mg)

Strength:

60 MG 30 MG

Gliclize 30 Mr Tablet 10 is primarily used to manage type 2 diabetes mellitus in adults. It belongs to a group of medicines known as sulfonylureas.

In addition to this primary use, the medicine can also be used with other oral antidiabetic agents or insulin when dietary measures, physical exercise, and weight reduction alone are insufficient to control blood glucose levels.

This medicine must be taken orally as directed by your doctor. Before taking it, inform your doctor about any pre-existing conditions or ongoing medications. If you notice any side effects while using this medicine, notify your doctor immediately. Remember to continue taking the tablet for the duration your doctor prescribes for optimal results.

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Gliclize 30 Mr Tablet 10 is used for the following:

Managing type 2 diabetes mellitus in adults: This is when dietary measures, physical exercise, and weight reduction alone do not effectively control blood glucose levels.
Can be used alone: In cases where no other oral antidiabetic agents or insulin are being used.
Can be combined with other oral antidiabetic agents or insulin: This is useful when multiple methods are needed to manage blood glucose levels.

Directions for Use of Gliclize 30 Mr Tablet 10

Here's how to take Gliclize 30 Mr Tablet 10:

The tablet must be swallowed whole with a glass of water.
It's crucial not to chew, crush or split the tablet.
Always take this medicine with breakfast.
Never exceed the recommended dose unless your doctor advises otherwise.
Always consult your doctor before discontinuing this medicine.

Gliclize 30 Mr Tablet 10 is taken orally.

Side Effects of Gliclize 30 Mr Tablet 10

Gliclize 30 Mr Tablet 10 may result in the following common side effects:

Hypoglycaemia: This refers to low blood sugar, with symptoms like sweating, trembling, and hunger. Severe cases can cause confusion or even seizures.
Gastrointestinal disturbances: This could include feeling nauseous, vomiting or experiencing abdominal pain.
Headache
Mild weight gain
Increased sensitivity to sunlight: Also known as photosensitivity, this could cause your skin to burn or rash more easily than usual when exposed to sunlight.
Rare but serious side effects include:
Liver disorders: Conditions like hepatitis or cholestatic jaundice.
Blood disorders: These could be conditions such as anaemia, leukopenia, or thrombocytopenia.
Skin reactions: Symptoms can range from rashes and itchiness to redness and raised skin spots.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Gliclize 30 Mr Tablet 10. However, if you experience any serious side effects or worsening symptoms, please consult your doctor.

Here's how you can manage two of the common side effects:

Hypoglycaemia: Regularly monitor your blood sugar levels to prevent them from dropping too low.
Gastrointestinal disturbances: Taking your medicine with meals can help minimise stomach discomfort.

Gliclize 30 Mr Tablet 10 contains gliclazide (30 mg), which works on your body in the following ways:

Stimulates insulin secretion: Gliclazide stimulates insulin release from the pancreas, a hormone necessary for regulating blood sugar levels.
Increases insulin sensitivity: Besides stimulating insulin secretion, gliclazide also helps your body's cells respond better to insulin, resulting in better glucose uptake and utilisation.
Inhibits hepatic glucose production: Gliclazide can also help manage blood glucose levels by reducing the amount of glucose your liver produces. This combined action helps manage blood sugar levels efficiently in people with type 2 diabetes.

Pregnancy

Gliclize 30 Mr Tablet 10 is not recommended for pregnant women. Consult your doctor before taking this medicine.

Breastfeeding

This medicine is contraindicated during breastfeeding. It would help if you discussed this with your doctor to understand the potential risks and benefits.

Alcohol

You should avoid consuming alcohol when taking Gliclize 30 Mr Tablet 10. It can potentiate the hypoglycemic effect, so it's best discussed with your doctor.

Liver

If you have liver health issues, exercise caution while taking this medication. Gliclazide is extensively metabolised in the liver and may affect liver function. Periodic monitoring of liver function is recommended.

Kidney

Caution is advised while taking Gliclize 30 Mr Tablet 10 if you have kidney problems. The medicine is contraindicated in severe renal failure. It is wise to consult your doctor before starting this medication.

Using Machines & Driving

There are no specific precautions for using machines or driving while taking this medicine. However, as hypoglycemia (low blood sugar) may occur, it is important to monitor your blood sugar levels regularly.

Allergy

If you have known allergies to gliclazide or any other sulfonylurea class of antidiabetic medications, avoid taking Gliclize 30 Mr Tablet 10. Always inform your doctor about your allergy history before starting a new medication.

Children

This medicine is meant for adults and isn't recommended for children under 18. Always consult with your doctor before giving any medicine to a child.

Older Patients

Elderly patients may be more susceptible to hypoglycemia and should, therefore, start with the lowest possible dose of Gliclize 30 Mr Tablet 10. Older patients should take this medicine under medical supervision.

Interactions of Gliclize 30 Mr Tablet 10

Drug-Drug Interactions

Gliclize 30 Mr Tablet 10 interacts with the following medicines:

Other antidiabetic medications: There's an increased risk of low blood sugar or hypoglycemia when taken with medicines like metformin and glipizide.
Beta-blockers: Medicines like propranolol can mask the symptoms of hypoglycemia, making it difficult to recognise and treat.
Anticoagulants: Coumarin-based medications like warfarin may have their blood-thinning effects enhanced, increasing the risk of bleeding.
Corticosteroids: Medications like prednisolone can reduce the efficacy of Gliclize 30 Mr Tablet 10 in lowering blood sugar levels.

Drug-Food Interactions

Certain foods can interact with Gliclize 30 Mr Tablet 10. These are:

High-sugar foods: Consuming sugary foods while on Gliclize 30 Mr Tablet 10 can counter its glucose-lowering effect, leading to high blood sugar levels.

Drug-Disease Interactions

Gliclize 30 Mr Tablet 10 interacts with the following diseases:

Renal Impairment: Individuals with kidney disease may need lower doses as Gliclize 30 Mr Tablet 10 is contraindicated in severe renal failure.
Hepatic Impairment: People with liver disease should use caution since gliclazide is extensively metabolised in the liver. Regular monitoring of liver function is advisable.
Hypoglycemia: Individuals who frequently experience low blood sugar should monitor their glucose levels closely while on Gliclize 30 Mr Tablet 10, as it can further lower blood sugar levels.

Daily Dose

The daily dose of Gliclize 30 Mr Tablet 10 should be taken as directed by your doctor. Dosage adjustments may be made based on individual factors such as your response to the medication and the severity of your condition. It's crucial to adhere to the prescribed dosage and not to alter it without discussing it with your doctor.

Over Dose

If you inadvertently take more than the prescribed amount of Gliclize 30 Mr Tablet 10, you might experience symptoms such as feeling shaky, sweating excessively, or a faster heartbeat, which are signs of low blood sugar levels. If you notice these symptoms, contact your doctor for advice.

Missed Dose

If you miss a dose of Gliclize 30 Mr Tablet 10, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed dose and continue with your regular schedule. Don't double up on doses without asking your doctor.

Store Gliclize 30 Mr Tablet 10 in a cool, dry place.
Keep it away from light and moisture to maintain its efficacy.
Ensure it's out of reach and sight of children to prevent accidental ingestion.
Always check the expiry date before use; discard if expired.

Make sure to maintain a balanced diet rich in fibre and low in sugars. This will aid in managing your blood sugar levels along with taking Gliclize 30 Mr Tablet 10.
Regular physical activity is essential. Incorporate mild exercises into your daily routine, as they boost insulin sensitivity, which helps control your blood glucose level. Always consult your doctor before starting any new exercise regimen.

Fact Box

Drug Category	Insulin Secretagogue
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet MR
Habit Forming	No
Ailment	Type 2 Diabetes

What is Gliclize 30 Mr Tablet 10 used for?

Gliclize 30 Mr Tablet 10 is used to manage type 2 diabetes in adults when diet and exercise aren't enough to control blood sugar levels.

How does Gliclize 30 Mr Tablet 10 work?

It works by promoting insulin release from your pancreas and increasing insulin sensitivity in the body, helping to control blood glucose levels.

How should I take Gliclize 30 Mr Tablet 10?

Take Gliclize 30 Mr Tablet 10 orally once daily with breakfast. Don't chew, crush or split the tablet. Swallow it whole with water.

What are the common side effects of Gliclize 30 Mr Tablet 10?

Common side effects include low blood sugar, stomach disturbances like nausea and vomiting, headache, and mild weight gain.

What precautions should I take while using Gliclize 30 Mr Tablet 10?

Monitor your blood glucose regularly, avoid alcohol, and consult your doctor before taking other medicines. Special caution is needed in case of kidney or liver problems.

Can I use Gliclize 30 Mr Tablet 10 during pregnancy or breastfeeding?

Gliclize 30 Mr Tablet 10 is not recommended during pregnancy or breastfeeding. Consult your doctor for safer alternatives during these periods.

What should I do in case of an overdose of Gliclize 30 Mr Tablet 10?

In case of an overdose, which can cause severe low blood sugar, seek immediate medical attention.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

Om Shanti Co-Operative Hsg. Society,Shop No-6, 2nd Floor, 44,, 42, Babu Genu Road, Kalbadevi, Mumbai, Maharashtra 400002

Country of origin: INDIA

References

Schernthaner, G. (2002). Gliclazide modified release: a critical review of pharmacodynamic, metabolic and vasoprotective effects. PubMed. Retrieved 1 April 2024, from https://pubmed.ncbi.nlm.nih.gov/12076188/
About gliclazide. (2022, April 1). nhs.uk. https://www.nhs.uk/medicines/gliclazide/about-gliclazide/
Gliclazide. (2024, August 2). DrugBank Online | Database for Drug and Drug Target Info. https://go.drugbank.com/drugs/DB01120
Campbell, D., Lavielle, R., & Nathan, C. (1991). The mode of action and clinical pharmacology of gliclazide: A review. Diabetes Research and Clinical Practice, 14, S21-S36. https://doi.org/10.1016/0168-8227(91)90005-x

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