Glimefide M 1/500 MG Tablet 10

Fidelity Lifescience

Pack of 10 Units

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MRP ~~₹55~~

₹44

₹5.5/Units

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Prescription required for this medicine

Store Below 30^o C

Composition

Glimepiride (1 Mg) + Metformin (500 Mg)

Glimefide M 1/500 MG Tablet 10 is primarily used to manage type 2 diabetes mellitus, a condition in which the body either does not produce enough insulin or does not sufficiently use the insulin it produces. This combination medicine falls under the category of oral antidiabetic medications.

This medicine also enhances the body's response to insulin. It is prescribed when diabetes cannot be managed by a single medication. It aids in reducing both fasting and post-meal blood glucose levels.

Taking this medicine should be as per your doctor's directions. Before starting the tablet, inform your doctor about any current health conditions or ongoing medications. Should you experience side effects while using this medicine, contact your doctor immediately. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

Glimefide M 1/500 MG Tablet 10 is mainly used to manage type 2 diabetes mellitus in adults.

Directions for Use of Glimefide M 1/500 MG Tablet 10

Swallow the tablet whole with water.
Refrain from crushing or chewing the tablet.
Always adhere to the recommended dose; do not exceed it without consulting your doctor.
Before stopping the medicine, it's essential to consult your doctor.

Glimefide M 1/500 MG Tablet 10 is taken orally.

Side Effects of Glimefide M 1/500 MG Tablet 10

Glimefide M 1/500 MG Tablet 10 may have the following common side effects:

Nausea
Vomiting
Abdominal pain
Diarrhoea
Loss of appetite
Hypoglycaemia (low blood sugar)

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the medicine. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

You can also effectively manage common side effects like nausea, vomiting, abdominal pain, and diarrhoea at home by taking the medicine with or after your meals.

How Glimefide M 1/500 MG Tablet 10 Works?

Glimefide M 1/500 MG Tablet 10 works in the human body in the following ways:

Glimepiride (1 mg): Belonging to the sulphonylurea class of antidiabetic agents, glimepiride manages blood sugar by stimulating the pancreas to produce more insulin.
Metformin (500 mg): Metformin is a biguanide that lowers blood sugar by decreasing glucose production in the liver, delaying glucose absorption in the intestines, and enhancing insulin sensitivity in the body.

Pregnancy

Glimefide M 1/500 MG Tablet 10 is contraindicated during pregnancy. If you are pregnant or planning to conceive, ensure to discuss this with your doctor before starting this medicine.

Breastfeeding

This medicine is contraindicated for breastfeeding women. Always consult your doctor to understand the potential risks and benefits of the medicine.

Alcohol

Avoid alcohol consumption while on this medication as it can increase the risk of lactic acidosis (a condition where lactic acid builds up in your body). Always consult your doctor regarding alcohol intake.

Liver

This medicine is contraindicated in patients with severe liver impairment as it may increase the risk of lactic acidosis. It is best to consult your doctor before taking this medicine.

Kidney

Patients with severe kidney impairment are also contraindicated from taking this medicine due to the risk of developing lactic acidosis. Always consult your doctor before starting this medicine.

Using Machines & Driving

This medicine may cause dizziness or blurred vision in some individuals. If you feel unwell or drowsy, avoid driving or operating machinery until you feel better.

Allergy

Glimefide M 1/500 MG Tablet 10 is contraindicated if you are allergic to glimepiride, metformin, or any other ingredients in the medicine. Ensure your doctor knows about any allergies you have.

Children

This medicine is meant for adult use and should not be given to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients, especially those with liver or kidney problems, should take this medicine under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Interactions of Glimefide M 1/500 MG Tablet 10

Drug-Drug Interactions

Glimefide M 1/500 MG Tablet 10 may interact with the following medications:

Beta-blockers: Medicines like metoprolol and propranolol can further lower your blood glucose levels, resulting in unwanted side effects.
Cardiovascular medications: Heart medications like digoxin, nifedipine, and quinidine may increase the level of metformin in your body, causing adverse effects.
Non-steroidal anti-inflammatory drugs (NSAIDs): NSAIDs like aspirin and ibuprofen may interact with glimepiride and further lower your blood glucose levels.

Drug-Food Interactions

Certain foods may interact with Glimefide M 1/500 MG Tablet 10. For instance:

High-fibre food: Consuming a diet high in fibre, like legumes, oatmeals, and fruits, may reduce the absorption of metformin, decreasing its effectiveness.

Drug-Disease Interactions

Glimefide M 1/500 MG Tablet 10 may interact with the following diseases:

Type 1 diabetes: This medicine is contraindicated in patients with type 1 diabetes.
Diabetic ketoacidosis: Patients with diabetic ketoacidosis are advised not to take this medicine.
Kidney or liver disease: Patients with severe kidney or liver impairment are contraindicated from using this medicine due to the increased risk of lactic acidosis.

Dosage of Glimefide M 1/500 MG Tablet 10

Daily Dose

The daily dose of Glimefide M 1/500 MG Tablet 10 should be as prescribed by your doctor. The dosage may vary based on individual factors like response to treatment and severity of the condition. For further details regarding dosage, please read the package insert.

Over Dose

In case of an overdose, you might experience side effects such as nausea, vomiting, diarrhoea, abdominal pain, and confusion. If these symptoms persist or worsen, inform your doctor promptly.

Missed Dose

If you forget to take your regular dose of the medicine, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular dosage schedule. Never adjust your dosage without consulting your doctor.

Store Glimefide M 1/500 MG Tablet 10 at room temperature, ideally below 25°C.
Keep the medicine in its original packaging to protect it from light and moisture.
Ensure that the medicine is out of reach of children.
Use this medicine before its expiry date.

Regularly monitor your blood sugar levels as directed by your doctor to assess the effectiveness of the medicine.
Maintain a balanced diet low in simple sugars and high in complex carbohydrates, which can help manage your diabetes better.
Following an exercise routine can also help manage your blood glucose levels to a certain extent. However, always consult your doctor before starting an exercise regimen. Work with a certified nutritionist to work around your diet.

Fact Box

Drug Category	Sulphonylurea, Biguanide
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 diabetes mellitus

What is Glimefide M 1/500 MG Tablet 10 used for?

This medicine helps manage type 2 diabetes mellitus in adults by controlling blood sugar levels when diet and exercise alone aren't sufficient.

How does Glimefide M 1/500 MG Tablet 10 work?

This medicine combines two active ingredients: glimepiride, which stimulates the pancreas to produce more insulin, and metformin, which reduces glucose production in the liver and improves insulin sensitivity. Together, these components help lower blood glucose levels.

Can I take Glimefide M 1/500 MG Tablet 10 if I'm pregnant or breastfeeding?

No, this medicine is contraindicated if you're pregnant or breastfeeding. Always consult your doctor for advice on managing diabetes during these times.

What should I do if I miss a dose of Glimefide M 1/500 MG Tablet 10?

If you miss a dose, take it as soon as you remember. However, if it's close to your next dose time, skip the missed one and continue with your regular schedule. Don't double the dose without consulting your doctor.

What are some side effects of Glimefide M 1/500 MG Tablet 10?

The common side effects of the medicine include hypoglycaemia (low blood sugar), stomach upset, nausea, vomiting, and diarrhoea. If these symptoms persist or worsen, consult your doctor immediately.

Can Glimefide M 1/500 MG Tablet 10 interact with other medicines?

Yes, some medicines may affect how Glimefide M 1/500 MG Tablet 10 works or is removed from your body. These include NSAIDs, beta-blockers, and heart medications. Always inform your doctor about all the medicines you are currently taking.

How should I store my Glimefide M 1/500 MG Tablet 10?

Store the medicine at room temperature below 25°C, in its original packaging, away from light and moisture.

Last Updated On 31 Dec. 2024 | 6:42AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

Nanasaheb Gaikwad Information Technology Park, S. No. 17/ 2B, 411007, 17/ 2B,, Baner - Aundh Rd, Sanewadi, Aundh, Pune, Maharashtra 411007

Country of origin: INDIA

References

Unknown. (2022). GLUCOPHAGE. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020357s037s039,021202s021s023lbl.pdf
AMARYL. (n.d.-b). AMARYL (glimepiride tablets) 1, 2, and 4 mg. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020496s021lbl.pdf
Glimepiride: Uses, interactions, mechanism of action | DrugBank Online. (n.d.-b). DrugBank. https://go.drugbank.com/drugs/DB00222
Glimepiride: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a696016.html
Metformin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00331
The mechanisms of action of metformin. (2017, August 3). ncbi.nlm.nih.gov. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552828/

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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