Glimicure M 2/500 MG Tablet 10

Hbc Lifesciences Pvt Ltd

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MRP ~~₹71.39~~

₹57.11

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Composition

Glimepiride (2 Mg) + Metformin (500 Mg)

Glimicure M 2/500 MG Tablet is primarily used to manage type 2 diabetes mellitus in adults. It is a combination medicine belonging to the class of antidiabetic drugs. This combines the effects of two active ingredients working together to help control blood sugar levels more effectively than a single medication.

In addition to controlling blood sugar, this medicine also helps in improving the overall metabolic profile of people with type 2 diabetes. It addresses both insulin resistance and insulin deficiency, which are the two main issues in type 2 diabetes, helping to maintain a more stable blood glucose level.

It's important to take this medicine as directed by your doctor. You must inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you experience any side effects while on this medicine, promptly notify your doctor. Remember to continue taking the medicine for the duration prescribed by your doctor for optimal results.

Glimicure M 2/500 MG Tablet is used for the following:

Managing type 2 diabetes in adults.
Assisting blood sugar control when diet and exercise alone are insufficient.
Helping to regulate insulin resistance and deficiency, two key factors in type 2 diabetes.

Directions for Use of Glimicure M 2/500 MG Tablet 10

Here's how to take Glimicure M 2/500 MG Tablet correctly:

Swallow the tablet whole with a glass of water.
Do not crush, chew or break the tablet.
Remember to take your medicine regularly to ensure its effectiveness.
If you have any queries about how to take this medication, consult your doctor.

Glimicure M 2/500 MG Tablet is taken orally.

Side Effects of Glimicure M 2/500 MG Tablet 10

Glimicure M 2/500 MG Tablet may have the following common side effects:

Hypoglycaemia
Nausea
Vomiting
Diarrhoea
Abdominal Pain
Headache
Lactic Acidosis: This is a build-up of lactic acid in your body, which can make you feel tired and weak.
Hyponatraemia: This means low sodium levels in your blood, which can cause symptoms like confusion, seizures, or loss of consciousness.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Glimicure M 2/500 MG Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Try taking Glimicure M 2/500 MG Tablet with food to lessen this effect.
Diarrhoea: Consider taking this medication with meals to manage this side effect better.

How Glimicure M 2/500 MG Tablet 10 Works?

Glimicure M 2/500 MG Tablet works through the combined action of two active ingredients:

Glimepiride (2 mg): This medicine belongs to a class of medications called sulfonylureas. It stimulates the cells in your pancreas (known as beta cells) to release more insulin. Insulin is the hormone that helps your body lower your blood sugar levels.
Metformin (500 mg): Metformin is a member of the biguanide class of antidiabetic drugs. It works by decreasing the amount of sugar your liver makes, reducing the amount of sugar your intestines absorb, and making your body more sensitive to insulin. This helps to lower your blood sugar levels. Unlike sulfonylureas, metformin doesn't cause your body to produce more insulin.

Pregnancy

If you are pregnant, it is best to exercise caution while taking Glimicure M 2/500 MG Tablet. It would be a good idea to consult your doctor before starting this medicine.

Breastfeeding

Caution is advised if you are lactating. Be sure to discuss with your doctor the potential risks and benefits before starting on Glimicure M 2/500 MG Tablet.

Alcohol

Drinking alcohol while using this medicine might enhance its hypoglycemic effect and increase the risk of lactic acidosis. Therefore, it is recommended to avoid excessive alcohol intake.

Liver

For those with liver issues, there should be caution when taking this medicine. It's advisable to discuss any liver-related concerns with your doctor before beginning treatment with Glimicure M 2/500 MG Tablet.

Kidney

If you have a history of kidney problems, caution is advised before using Glimicure M 2/500 MG Tablet. A consultation with your doctor would be beneficial before taking this medicine.

Using Machines & Driving

This medication does not usually affect your ability to drive or operate machinery. However, if you experience side effects like dizziness or blurred vision, avoid such activities until you are sure you can perform them safely.

Allergy

If you have known hypersensitivity to glimepiride, metformin, or any other components of Glimicure M 2/500 MG Tablet, do not take this medicine. Inform your doctor of any allergies you may have before commencing treatment.

Children

This medicine is not typically recommended for children under 18 years old. If considering giving this medication to a child, consult a doctor first.

Older Patients

Older patients should take this medication under medical supervision as they may be more susceptible to its side effects. If you are above 70 years of age, consult your doctor who will guide you based on your health status.

Interactions of Glimicure M 2/500 MG Tablet 10

Drug-Drug Interactions

Glimicure M 2/500 MG Tablet interacts with the following medicines:

Salicylates and Sulfonamides: These medicines, which include aspirin and sulfamethoxazole, are highly protein-bound and may interact with glimepiride. The interaction can modify the blood sugar-lowering effect of Glimicure M 2/500 MG Tablet.
CYP2C9 Enzyme Inducers: Medicines like rifampin that induce the CYP2C9 enzyme can reduce the effectiveness of glimepiride in Glimicure M 2/500 MG Tablet.
CYP2C9 Enzyme Inhibitors: Medicines like fluconazole that inhibit the CYP2C9 enzyme may enhance the blood sugar-lowering effect of glimepiride present in Glimicure M 2/500 MG Tablet.
Cationic Medicines: Medicines such as amiloride, digoxin, and vancomycin are eliminated by renal tubular secretion and can interact with metformin in Glimicure M 2/500 MG Tablet, potentially leading to higher levels of metformin in the body.

Drug-Food Interactions

Certain foods might interact with Glimicure M 2/500 MG Tablet:

High-Fat Meals: Consuming high-fat meals while on this medication can slow down the absorption of glimepiride and impact its effectiveness.

Drug-Disease Interactions

Glimicure M 2/500 MG Tablet interacts with the following diseases:

Renal Impairment: Patients with kidney problems should use this medicine cautiously. It can affect kidney function and might need dose adjustment.
Liver Disease: This medicine should be used cautiously in patients having impaired liver function due to its potential to impact the liver.
Congestive Heart Failure: Glimicure M 2/500 MG Tablet should be used with caution in patients with heart failure, as it can affect heart function.

Dosage of Glimicure M 2/500 MG Tablet 10

Daily Dose

Your daily dose of Glimicure M 2/500 MG Tablet should be as advised by your doctor, based on factors like the severity of your condition and how you respond to the medicine. Never exceed the prescribed dosage without consulting your doctor.

Over Dose

If you've accidentally taken more Glimicure M 2/500 MG Tablet than recommended, you might feel nauseous or experience diarrhoea. Though these are common side effects, if you notice them intensifying, it's wise to inform your doctor.

Missed Dose

If you miss your dose of Glimicure M 2/500 MG Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, just skip the missed one and continue with your regular schedule. Don't increase your dosage without consulting your doctor.

Store Glimicure M 2/500 MG Tablet at room temperature, ideally between 15-30°C.
Keep it in a dry place, away from light and moisture to maintain its effectiveness.
Make sure it is out of reach and sight of children.
Use the tablet before its expiry date for maximum benefits.

Maintain a balanced diet with low sugar intake. This helps manage your blood sugar levels, enhancing the effectiveness of Glimicure M 2/500 MG Tablet.
Limit your alcohol consumption. Excessive alcohol can enhance the hypoglycaemic effect of this medicine and raise the risk of lactic acidosis. Always consult your doctor for personalised advice on alcohol intake while on this medication.

Fact Box

Drug Category	Sulfonylurea, Biguanide
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes

What is the correct way to take Glimicure M 2/500 MG Tablet?

Glimicure M 2/500 MG Tablet is taken orally. Swallow the tablet whole with water.

What should I do if I miss a dose of Glimicure M 2/500 MG Tablet?

If you miss a dose, take it as soon as you remember. However, if it's nearly time for the next dose, skip the missed one and continue with your regular schedule.

Can I consume alcohol while taking Glimicure M 2/500 MG Tablet?

It's advised to avoid alcohol consumption while taking this medication, as it can enhance the hypoglycaemic effect and increase your risk of lactic acidosis.

How does Glimicure M 2/500 MG Tablet work in managing type 2 diabetes?

This medicine helps manage type 2 diabetes by increasing insulin release (glimepiride) and improving insulin sensitivity (metformin), thus controlling blood sugar levels.

Are there any side effects of taking Glimicure M 2/500 MG Tablet?

Common side effects may include hypoglycemia, nausea, vomiting, diarrhoea, abdominal pain, and headache. Always consult your doctor if you experience any side effects.

What precautions should I take while using Glimicure M 2/500 MG Tablet?

This medicine should be used cautiously if you have kidney issues, liver problems, or heart failure. Avoid excessive alcohol intake and stay hydrated.

Are there any specific medicines that interact with Glimicure M 2/500 MG Tablet?

Certain medicines, such as salicylates, sulfonamides, NSAIDs and cationic drugs may interact with this medication. Always inform your doctor about all medicines you are currently taking.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 3 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

103, KH Rd, Sargasan, Gandhinagar, Gujarat 382421

Country of origin: INDIA

References

MedlinePlus. (2024). Glimepiride. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a696005.html
National Health Service. (2024). How and when to take Glimepiride. Retrieved 1 April 2024, from https://www.nhs.uk/medicines/glimepiride/how-and-when-to-take-glimepiride/
U.S. Food and Drug Administration. (2006). Drug label. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021748s002lbl.pdf
Sahay, R. K., Mittal, V., Gopal, G. R., Kota, S., Goyal, G., Abhyankar, M., & Revenkar, S. (2020). Glimepiride and Metformin Combinations in Diabetes Comorbidities and Complications: Real-World Evidence. Cureus, 12(9), e10700. https://doi.org/10.7759/cureus.10700
Jeon, H. J., & Oh, T. K. (2011). Comparison of vildagliptin-metformin and glimepiride-metformin treatments in type 2 diabetic patients. Diabetes & metabolism journal, 35(5), 529–535. https://doi.org/10.4093/dmj.2011.35.5.529

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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