Gluxit S 10100 Mg Tablet 10

Gluxit S 10/100 Tablet 10

Eris Lifesciences Ltd

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Composition

Dapagliflozin (10 Mg) + Sitagliptin (100 Mg)

Gluxit-S 10/100 Tablet is primarily used to manage type 2 diabetes mellitus in adults. It is a combination medicine, falling under the category of antidiabetic medications.

This tablet also aids in glycemic control, improving the level of sugar in your blood when paired with an appropriate diet and regular exercise.

You must take this medicine as directed by your doctor. Before starting this medicine, make sure to inform your doctor about any ongoing treatments or pre-existing conditions. If you experience any side effects while on this medicine, notify your doctor immediately. To achieve the best results, continue taking the medicine for the entire duration prescribed by your doctor.

Gluxit-S 10/100 Tablet is used in the management of the following conditions:

Improvement of sugar control in adults with type 2 diabetes mellitus: This condition is characterised by high blood sugar levels due to the body's inefficiency in using or producing insulin.
Supplement to diet and exercise for better glycemic control: Dietary changes and regular physical activity are often not enough on their own. In such cases, this medicine can help achieve desired sugar levels.
Use in combination therapy for type 2 diabetes mellitus: When other medications, such as metformin alone, don't provide adequate sugar control, Gluxit-S 10/100 Tablet can be added to the treatment regimen.

Directions for Use of Gluxit S 10/100 Tablet 10

Swallow the tablet whole with a glass of water.
Don't crush, split, or chew the tablet.
Never exceed the recommended dosage without consulting your doctor.
Always remember that stopping this medicine should only be done under your doctor's advice.

Gluxit-S 10/100 Tablet is taken orally.

Side Effects of Gluxit S 10/100 Tablet 10

Gluxit-S 10/100 Tablet may cause the following common side effects:

Genital mycotic infections
Nasopharyngitis
Urinary tract infections
Headache
Upper respiratory tract infections
Diarrhoea
Nausea
Back pain
Arthralgia: This refers to joint pain, which can occur in any part of your body where two or more bones meet.
Hypoglycaemia: This is a condition where your blood sugar level drops below normal.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Gluxit-S 10/100 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some general guidelines for managing common side effects:

Diarrhoea: Increase your water intake and consume a lot of healthy fluids to avoid dehydration.
Nausea: If you feel nauseated after taking this medicine, you may want to take it after meals.

Gluxit-S 10/100 Tablet contains two active ingredients:

Dapagliflozin (10 mg): This ingredient acts as a sodium-glucose cotransporter 2 (SGLT2) inhibitor. SGLT2 is involved in glucose reabsorption in your kidneys. By inhibiting this process, dapagliflozin causes more glucose to be removed from your body through urine, thus lowering blood glucose levels.
Sitagliptin (100 mg): This component works as a dipeptidyl peptidase-4 (DPP-4) inhibitor. DPP-4 usually breaks down certain hormones called incretins (GLP-1 and GIP). By inhibiting DPP-4, sitagliptin increases the levels of these hormones which stimulate insulin production when blood sugar levels are high and reduce glucagon release, thereby reducing blood glucose levels.

Pregnancy

Caution is advised while taking Gluxit-S 10/100 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

The active ingredients in Gluxit-S 10/100 Tablet are excreted in human milk. Consideration should be given to discontinuing nursing or discontinuing the medication based on the importance of the medicine to the mother.

Alcohol

There is no interaction of alcohol with Gluxit-S 10/100 Tablet. Nonetheless, it's always wise to discuss your drinking habits with your doctor when prescribed this medicine.

Liver

As with any medicine, it's advised to consult your doctor before starting it.

Kidney

Gluxit-S 10/100 Tablet is not recommended for individuals with moderate to severe kidney impairment or end-stage renal disease. If you have a history of kidney problems, be sure to discuss this with your doctor.

Using Machines & Driving

If you experience any side effects that could affect your ability, such as dizziness or fatigue, avoid these activities and speak to your doctor.

Allergy

This medicine is contraindicated for those who have had a serious hypersensitivity reaction to dapagliflozin, sitagliptin, or any other component present in Gluxit-S 10/100 Tablet.

Children

The safety and effectiveness of Gluxit-S 10/100 Tablet for use in children have not been established. Always consult your doctor before giving this medicine to a child.

Older Patients

No significant differences in safety or effectiveness were observed between older and younger patients on Gluxit-S 10/100 Tablet. However, some older individuals may be more sensitive, so caution and medical supervision are advised.

Interactions of Gluxit S 10/100 Tablet 10

Drug-Drug Interactions

Gluxit-S 10/100 Tablet interacts with the following medicines:

Insulin and Insulin Secretagogues: When used in combination with Gluxit-S 10/100 Tablet, these medicines, such as glimepiride and insulin glargine, may increase the risk of hypoglycaemia. A lower dose of these medicines may be needed.
Diuretics: Medicines like furosemide or hydrochlorothiazide, when taken with Gluxit-S 10/100 Tablet, could enhance the risk of volume depletion and hypotension.

Drug-Food Interactions

There are no specific food items known to interact with Gluxit-S 10/100 Tablet.

Drug-Disease Interactions

Gluxit-S 10/100 Tablet interacts with the following diseases:

Renal Impairment: This medicine is not recommended for patients with moderate to severe renal impairment or end-stage renal disease as its components, dapagliflozin and sitagliptin, can worsen kidney function.
Type 1 Diabetes Mellitus and Diabetic Ketoacidosis: Gluxit-S 10/100 Tablet should not be used in patients with type 1 diabetes or diabetic ketoacidosis as it may not provide the required insulin for carbohydrate metabolism.

Daily Dose

The recommended daily dose of Gluxit-S 10/100 Tablet should be taken as directed by your doctor. The dosage might vary based on individual factors such as the severity of your condition and how well you respond to the medication. It's crucial to follow the prescribed dosage and not exceed it without asking your doctor.

Over Dose

If you accidentally take more Gluxit-S 10/100 Tablets than prescribed, you could experience some common side effects like nausea or headaches in a more severe form. If these symptoms persist, it's important to inform your doctor.

Missed Dose

If you forget to take Gluxit-S 10/100 Tablet at the usual time, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never increase your dose without speaking with your doctor.

Store Gluxit-S 10/100 Tablet at room temperature, ideally below 30°C.
Keep it in a dry place, away from moisture.
Protect the medicine from direct sunlight and heat.
Always keep Gluxit-S 10/100 Tablet out of reach of children.
Ensure to use this medicine before its expiry date.

Maintain a balanced diet that is low in sugar and high in fibre. This helps manage your blood glucose levels, which is essential when you're taking Gluxit-S 10/100 Tablet for type 2 diabetes mellitus.
Regular exercise, such as walking or cycling, can also help lower your blood glucose levels. Please consult your doctor to plan an exercise routine that's safe for you.

Fact Box

Drug Category	SGLT2 Inhibitor, DPP-4 Inhibitor.
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus

What is Gluxit-S 10/100 Tablet used for?

Gluxit-S 10/100 Tablet is used to manage blood sugar levels in adults with type 2 diabetes, alongside a healthy diet and regular exercise.

How does Gluxit-S 10/100 Tablet work?

This medicine works by reducing sugar reabsorption in the kidneys and increasing insulin secretion from the pancreas, thereby lowering blood sugar levels.

Can I take Gluxit-S 10/100 Tablet if I have kidney problems?

If you have mild renal impairment, no dosage adjustment is necessary. However, if you have moderate to severe renal impairment or end-stage renal disease, avoid using this tablet.

What are the possible side effects of Gluxit-S 10/100 Tablet?

Possible side effects include genital mycotic infections, nasopharyngitis, urinary tract infections, headache, upper respiratory tract infections, diarrhoea, nausea, back pain, arthralgia and hypoglycaemia.

Does Gluxit-S 10/100 Tablet interact with other medications?

Yes, it can interact with other medications like digoxin. If you're taking any other medicines, it's best to consult your doctor before starting Gluxit-S 10/100 Tablet.

Can pregnant or lactating women take Gluxit-S 10/100 Tablet?

The use of Gluxit-S 10/100 Tablet during pregnancy or lactation should be considered only if the potential benefit justifies the potential risk to the baby.

How should I store Gluxit-S 10/100 Tablet?

Store this tablet at room temperature below 30°C. Ensure the tablets are protected from moisture and kept in a tightly closed container.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Shivarth Ambit, Plot No. 142/2, Ramdas Road, Off SBR, Near Swati Bungalows, Ahmedabad, Gujarat - 380054

Country of origin: INDIA

References

AstraZeneca. (2014). HIGHLIGHTS OF PRESCRIBING INFORMATION [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/202293s020lbl.pdf
Dapagliflozin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06292
Merck Sharp & Dohme Corp. (2006). Highlights of prescribing information [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021995s019lbl.pdf
Sitagliptin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01261

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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