Glyree Mv 025002 Mg Tablet Pr 10

Glyree Mv 2 Tablet 10

Ipca Laboratories Pvt Ltd.

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Composition

Glimepiride (2 Mg) + Metformin (500 Mg) + Voglibose (0.2 Mg)

Glyree MV 2 Tablet is primarily used in the management of type 2 diabetes mellitus in adults. This oral medication is a combination medicine and belongs to the class of antidiabetic medications.

Besides managing type 2 diabetes, this medicine also helps in reducing the risk of complications associated with diabetes. These complications include kidney damage, blindness, nerve problems, limb amputations, and sexual dysfunction.

You should take this medicine as directed by your doctor. Be sure to inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you experience any side effects while on this medicine, notify your doctor immediately. It's important to continue taking the medicine for the duration prescribed by your doctor for optimal results.

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Glyree MV 2 Tablet is used for the following:

Managing type 2 diabetes mellitus: This medicine helps control high blood sugar levels in adults.
Reducing the risk of kidney damage: It can help protect your kidneys, which can be adversely affected by diabetes.
Preventing nerve problems: Diabetes can lead to nerve damage, and this medicine helps mitigate that risk.
Lowering the chances of blindness: Diabetes may cause eye problems, and this medication assists in reducing this risk.

Directions for Use of Glyree Mv 2 Tablet 10

Here's how you should take Glyree MV 2 Tablet:

Do not crush, cut, or chew the tablet.
Remember that it's normal to see remnants of the extended-release tablet in your stool.
Never exceed your doctor’s recommended dose.

Glyree MV 2 Tablet is taken orally.

Glyree MV 2 Tablet may have the following common side effects:

Hypoglycaemia
Diarrhoea
Nausea
Vomiting
Abdominal pain
Flatulence: This is a fancy term for gas trapped in your digestive system.
Dyspepsia: Also known as indigestion, it can cause discomfort in your stomach.
Vitamin B12 deficiency: This can lead to weakness and tiredness.
Rash

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Glyree MV 2 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Consume plenty of water and healthy fluids to avoid dehydration.
Dyspepsia: If you have indigestion, take this medicine after meals to reduce the discomfort.

Glyree MV 2 Tablet comprises three active ingredients:

Glimepiride (2 mg): This sulfonylurea stimulates insulin secretion from the beta cells in your pancreas. It may also have additional effects outside the pancreas.
Metformin hydrochloride (500 mg): This biguanide reduces the production of glucose in your liver, decreases the absorption of glucose in your intestines, and improves insulin sensitivity. This ultimately helps in reducing blood glucose levels.
Voglibose (0.2 mg): As an alpha-glucosidase inhibitor, it delays carbohydrate digestion and absorption in the small intestine, thus reducing post-meal blood sugar spikes.

Pregnancy

Glyree MV 2 Tablet is not recommended during pregnancy. If you're pregnant or planning to conceive, discuss this with your doctor before starting this medication.

Breastfeeding

Breastfeeding mothers are advised to talk to their doctor before taking Glyree MV 2 Tablet.

Alcohol

Consuming alcohol while on Glyree MV 2 Tablet can heighten the risk of lactic acidosis and hypoglycaemia. It's best to discuss your alcohol habits with your doctor before starting this medicine.

Liver

Caution is advised while taking Glyree MV 2 Tablet if you have any liver health issues. It's advisable to discuss these concerns with your doctor before starting the medication.

Kidney

Glyree MV 2 Tablet is contraindicated for people with severe renal impairment. If you have any kidney problems, it's important to mention them to your doctor before taking this medicine.

Using Machines & Driving

This medicine may cause side effects such as dizziness or fatigue which could affect your ability to drive or operate machinery. It's best to avoid such activities until you know how the medicine affects you.

Allergy

If you're allergic to glimepiride, metformin, voglibose, or any other ingredients in Glyree MV 2 Tablet, don't take this medicine. Let your doctor know about any previous allergic reactions.

Children

Giving Glyree MV 2 Tablet to children under 18 years of age should be done with caution. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Glyree MV 2 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Glyree MV 2 Tablet interacts with the following medicines:

Diuretics: Medicines such as furosemide and hydrochlorothiazide may cause an imbalance in blood sugar levels when taken with Glyree MV 2 Tablet.
Corticosteroids: Medicines like prednisone and cortisone can lead to hyperglycaemia when taken with Glyree MV 2 Tablet.
Oral Contraceptives: Hormonal contraceptives like levonorgestrel and ethinyl estradiol may decrease the effectiveness of Glyree MV 2 Tablet in managing blood sugar levels.
Anti-epileptic medications: Phenytoin, when taken along with Glyree MV 2 Tablet, may increase the risk of hypoglycaemia.
Lipid-lowering medications: Medicines like gemfibrozil and niacin could increase the risk of hypoglycaemia when taken with Glyree MV 2 Tablet.

Drug-Food Interactions

Drug-Disease Interactions

Glyree MV 2 Tablet interacts with the following diseases:

Renal Impairment: Glyree MV 2 Tablet should be used carefully if you have kidney problems, as it could further impair kidney function.
Liver Disease: If you have liver disease, this medicine may affect your liver function, hence caution is advised.
Congestive Heart Failure: Patients suffering from heart failure need to be cautious, as Glyree MV 2 Tablet can affect heart function adversely.
Hypoxic States: If you have conditions that lead to less oxygen supply to tissues, such as severe heart disease or respiratory failure, the use of this medicine may cause a dangerous build-up of lactic acid in your blood.
Adrenal or Pituitary Insufficiency: If you have adrenal or pituitary gland problems, Glyree MV 2 Tablet could affect your body's hormonal balance.

Daily Dose

Your daily dose of Glyree MV 2 Tablet will be as per your doctor's prescription. This dosage might vary based on factors such as your health condition and how well you respond to the medicine. Always adhere to the prescribed dosage and never exceed it without consulting your doctor.

Over Dose

If you accidentally take more than the prescribed dose of Glyree MV 2 Tablet, you may experience common side effects like nausea or headaches. In such scenarios, it's advisable to inform your doctor about this incident.

Missed Dose

In case you forget to take your regular dose of Glyree MV 2 Tablet, take it as soon as you remember. However, if it's almost time for the next dose, skip the missed one and continue with your regular schedule. Never alter your dosage without consulting your doctor.

Store your Glyree MV 2 Tablet in a cool, dry place where the temperature stays below 25°C.
Keep it away from direct sunlight and moisture.
Make sure the medicine is out of reach of children.
Always check the expiry date before taking this medicine.

Try to maintain a balanced diet that is low in sugar and high in fibre. This can help manage your blood glucose levels along with Glyree MV 2 Tablet.
Regular physical activity such as walking or yoga can help increase your body's insulin sensitivity, which aids in managing type 2 diabetes effectively. Remember to consult your doctor before starting any new exercise routine.

Fact Box

Drug Category	Sulfonylurea, Biguanide, Alpha-glucosidase Inhibitor
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 diabetes mellitus

What is Glyree MV 2 Tablet used for?

Glyree MV 2 Tablet is used to manage type 2 diabetes mellitus in adults, alongside a suitable diet and exercise regimen.

What's in Glyree MV 2 Tablet?

The tablet contains Glimepiride, Metformin and Voglibose. These three active ingredients work together to help control blood glucose levels.

How should I take Glyree MV 2 Tablet?

It should be swallowed whole with your meal of the day. It is important not to crush, cut, or chew the tablet.

Can I take Glyree MV 2 Tablet if I have kidney problems?

If you have severe renal impairment, Glyree MV 2 Tablet is not recommended. Always consult your doctor before starting any new medication.

What are the side effects of Glyree MV 2 Tablet?

Common side effects may include hypoglycaemia, gastrointestinal disorders, vitamin B12 deficiency, headache and rashes. Consult your doctor if these persist or worsen.

Does Glyree MV 2 Tablet interact with other medicines?

Yes, it may interact with several medications such as diuretics, corticosteroids and alcohol among others. Always discuss your current medication with your doctor.

How should I store Glyree MV 2 Tablet?

Store the medicine below 25°C in a cool, dry place and keep it out of reach of children.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

125, Charkop Rd, Kandivali, Charkop, Charkop Industrial Estate, Kandivali West, Mumbai, Maharashtra 400067

Country of origin: INDIA

References

Langtry, H. D., & Balfour, J. A. (1998). Glimepiride. A review of its use in the management of type 2 diabetes mellitus. Drugs, 55(4), 563–584. https://doi.org/10.2165/00003495-199855040-00007
DailyMed. (n.d.). METFORMIN ER 500 MG tablet. Retrieved 1 April 2024, from https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=b857eccf-b9ff-45ba-8241-f47f5caada2a
Glimepiride: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00222
Voglibose: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB04878
Choi, H. K., Oh, M., Kim, E. J., Song, G. S., Ghim, J. L., Shon, J. H., Kim, H. S., & Shin, J. G. (2015). Pharmacokinetic study of metformin to compare voglibose/metformin fixed-dose combination with co administered voglibose and metformin. International journal of clinical pharmacology and therapeutics, 53(2), 147–153. https://pmc.ncbi.nlm.nih.gov/articles/PMC4558629/

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