Golbi 150 Mg Tablet 15

Golbi 150 Tablet 15

Intas Pharmaceuticals Ltd

STRIP of 10 Units
STRIP of 15 Units

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Composition

Ursodeoxycholic Acid (150 Mg)

Strength:

300 MG 150 MG

Golbi 150 Tablet 15 is primarily used to manage certain liver and gallbladder conditions. This medicine belongs to the class of hepatoprotective agents.

This medicine is also beneficial for dissolving certain types of cholesterol-rich gallstones. It also effectively manages primary biliary cholangitis, a chronic liver disease, by delaying its progression to more severe conditions like cirrhosis and liver failure.

Inform your doctor about any pre-existing conditions and medications you are currently taking. If you experience any side effects while using this medication, report them to your doctor immediately. For optimal results, it's crucial to continue taking the medicine for the prescribed time period.

Golbi 150 Tablet 15 is used for the following:

Dissolving specific types of cholesterol-rich gallstones
Managing primary biliary cholangitis, a long-term liver disease

Directions for Use of Golbi 150 Tablet 15

Swallow the tablet whole with a glass of water.
You can take it with or without food.
Do not crush, break, or chew the tablet.
Taking the medicine after your evening meal might enhance gallstone dissolution.
It's crucial to continue taking this medicine. Do not discontinue it without speaking to your doctor first.

Golbi 150 Tablet 15 is taken orally.

Golbi 150 Tablet 15 can lead to the following side effects:

Abdominal pain or discomfort
Diarrhoea
Nausea
Hardening of the gallstones
Hair thinning

Managing the Side Effects:

Most side effects are temporary, usually mild, and resolve upon discontinuing the use of Golbi 150 Tablet 15. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

Here are some helpful tips for handling some common side effects:

Abdominal pain or discomfort: Try taking Golbi 150 Tablet 15 with food to mitigate stomach upset.
Diarrhoea: Consuming the medicine after an evening meal can help lessen this effect.

Golbi 150 Tablet 15 contains ursodeoxycholic acid (150 mg), which acts on the body in the following ways:

Reduces cholesterol saturation: It decreases cholesterol absorption from the intestine and its production by the liver, reducing cholesterol saturation in the bile.
Enhances bile flow: Ursodeoxycholic acid improves bile flow and enhances bile acid secretion, which helps flush out toxic substances from the body.
Protects liver cells: This compound safeguards liver cells from damage caused by toxic bile acids.
Anti-inflammatory and immunomodulatory properties: Ursodeoxycholic acid has anti-inflammatory properties that reduce inflammation and immunomodulatory effects that help regulate the immune response.

These mechanisms help dissolve cholesterol gallstones gradually and improve liver function in patients with primary biliary cholangitis.

Pregnancy

Caution is advised while taking Golbi 150 Tablet 15 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, be sure to discuss the use of Golbi 150 Tablet 15 with your doctor to understand the potential risks and benefits.

Alcohol

Exercise caution if you are consuming alcohol while taking Golbi 150 Tablet 15. It's always wise to minimise alcohol intake when managing a health condition.

Liver

Golbi 150 Tablet 15 is often prescribed for liver conditions. However, if you have severe liver disease or other specific liver problems, like ascites, it's advisable to consult your doctor before starting this medicine.

Kidney

Caution is advised before using Golbi 150 Tablet 15 if you have a history of kidney problems. It is a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

Golbi 150 Tablet 15 does not have side effects that can impact your ability to operate machinery or drive. If you experience any side effects that could affect these activities, please consult your doctor.

Allergy

If you have a known hypersensitivity to bile acids, Golbi 150 Tablet 15 should not be used. Always inform your doctor about any known allergies you have.

Children

Golbi 150 Tablet 15 is meant for adult use. Caution is advised when giving this medicine to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Golbi 150 Tablet 15 under medical supervision, as they could be more vulnerable to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Golbi 150 Tablet 15 interacts with the following medicines:

Antacids: Medicines like aluminium hydroxide can decrease the absorption of Golbi 150 Tablet 15, reducing its effectiveness.
Bile acid sequestrants: Medicines such as cholestyramine and colestipol can also reduce the absorption of Golbi 150 Tablet 15.
Oestrogens: Hormonal medicines like ethinyl oestradiol can increase the risk of gallstones, potentially limiting the effectiveness of Golbi 150 Tablet 15.
Lipid regulating agents: Medicines like clofibrate can also increase the risk of gallstone formation when taken with Golbi 150 Tablet 15.

Drug-Food Interactions

There are no known food interactions with Golbi 150 Tablet 15.

Drug-Disease Interactions

Golbi 150 Tablet 15 interacts with the following diseases:

Biliary obstruction: If you have complete biliary obstruction, Golbi 150 Tablet 15 could worsen your condition.
Kidney impairment: If you have kidney problems, it's important to use Golbi 150 Tablet 15 with caution, as it may impact kidney function.
Certain liver conditions: Conditions like ascites might be affected by Golbi 150 Tablet 15. It's essential to use this medicine cautiously if you have any liver conditions.

Daily Dose

Your daily dose of Golbi 150 Tablet 15 should be taken as directed by your doctor. This can vary depending on the severity of your condition and how you respond to the medicine. It's crucial to stick to your prescribed dose and avoid exceeding it unless your doctor advises otherwise.

Over Dose

If you accidentally take more Golbi 150 Tablet 15 than prescribed, you could experience severe diarrhoea. In the case of an overdose, contact your doctor immediately for advice.

Missed Dose

If you forget to take your Golbi 150 Tablet 15, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and carry on as usual with your schedule. Never double your dose to make up for a missed one without checking with your doctor first.

Store your Golbi 150 Tablet 15 at room temperature in a cool, dry place.
Keep the product shielded from light and moisture.
Ensure the medicine is stored in a place inaccessible to children and pets.
Use the Golbi 150 Tablet 15 before its expiration date for optimal efficacy.

Limit your alcohol intake, as it can impact your liver.
Eat a low-fat, high-fibre diet rich in vegetables and whole grains. Avoid fatty, greasy, and spicy foods.

Fact Box

Drug Category	Bile Acid
Therapeutic Category	Hepatoprotective
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Gallstones, Primary biliary cholangitis

What is Golbi 150 Tablet 15 used for?

Golbi 150 Tablet 15 is primarily used to manage certain liver conditions and dissolve certain types of cholesterol-based gallstones.

How does Golbi 150 Tablet 15 work?

Golbi 150 Tablet 15 contains ursodeoxycholic acid, which reduces cholesterol absorption and production, increases bile flow, and protects liver cells from toxic substances.

Can I take Golbi 150 Tablet 15 with other medications?

Certain medicines, like antacids, can interact with Golbi 150 Tablet 15. Always consult your doctor before taking any other medicines alongside Golbi 150 Tablet 15. If needed, maintain a 2–4-hour gap between doses.

How long does it take for Golbi 150 Tablet 15 to dissolve gallstones?

Gallstone dissolution with Golbi 150 Tablet 15 is a slow process and may take several months, depending on the size, number, and type of gallstones. Regular ultrasound monitoring is required to assess progress.

What if I forget to take a dose of Golbi 150 Tablet 15?

Take the missed dose as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to compensate.

Can I stop taking Golbi 150 Tablet 15 if my symptoms improve?

No, you should not stop the medication without consulting your doctor, even if you feel better. Suddenly, stopping treatment may worsen your condition.

What dietary changes can aid gallstone treatment?

Eating a low-fat, high-fibre diet rich in vegetables and whole grains may help to improve your condition. Avoid fatty, greasy, and spicy foods. Maintain a healthy body weight and stay hydrated. Regular exercise can also improve outcomes.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Saniya K Mulla

Medical Writer & Reviewer | 5 years

MBBS

Check out Editorial Policy

Manufacturer details

Corporate House, Near Sola Bridge, S. G. Highway, Thaltej, Ahmedabad 380054, Gujarat, India

Country of origin: INDIA

References

U.S. Food and Drug Administration. (2023, Jan). Ursodiol tablet label. https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/020675s028lbl.pdf
DailyMed. (2023, Dec). Ursodiol capsule. FDA. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=d58f4da2-bc59-4bf3-b851-1fdb73b8cccd
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 31401, Ursodiol. https://pubchem.ncbi.nlm.nih.gov/compound/Ursodiol
DrugBank Online. (2024, May 30). Ursodeoxycholic acid. https://go.drugbank.com/drugs/DB01586
Paumgartner, G., & Beuers, U. (2004). Mechanisms of action and therapeutic efficacy of ursodeoxycholic acid in cholestatic liver disease. Clinics in Liver Disease, 8(1), 67–81. https://doi.org/10.1016/s1089-3261(03)00135-1
Achufusi, T. G. O., Safadi, A. O., & Mahabadi, N. (2023). Ursodeoxycholic acid. In StatPearls. https://pubmed.ncbi.nlm.nih.gov/31424887/

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