Gotrin 0125 Mg Tablet 10

Gotrin 0.125 MG Tablet 10

Rekvina Pharmaceuticals

Pack of 10 Units

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₹40.59

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Composition

Methylergometrine (0.125 Mg)

Gotrin 0.125 MG Tablet 10 is primarily used to manage excessive bleeding from the uterus which may occur post childbirth or abortion. This medicine is part of a group known as ergot alkaloids.

This tablet also helps manage the third stage of labour to assist in expelling the placenta. It is also used to prevent postpartum haemorrhage, and promotes uterine involution after childbirth by treating uterine subinvolution.

It is important that you consult your doctor for an accurate dosage and frequency as per your specific medical condition. Before starting this medicine, you should inform your doctor about any pre-existing health conditions or ongoing medicines. If you experience any side effects while taking this medicine, notify your doctor right away. For optimal results, it's crucial that you continue the medicine for the duration prescribed by your doctor.

Gotrin 0.125 MG Tablet 10 is utilised for managing the following health conditions:

Controlling excessive bleeding from the womb after childbirth or termination of pregnancy
Preventing severe blood loss after delivery, known as postpartum haemorrhage
Assisting in effectively managing the third stage of labour to help remove the placenta
Aiding in resolving a condition known as uterine subinvolution and promoting the process of uterine involution following childbirth

Directions for Use of Gotrin 0.125 MG Tablet 10

Consume this medicine orally as instructed by your doctor.
Swallow the tablet whole with a glass of water.
Abstain from crushing, chewing or breaking the tablet.
The precise dose and duration will be determined by your doctor depending on your condition and response.
Remember not to stop taking this medicine without prior consultation with your doctor.

Gotrin 0.125 MG Tablet 10 is taken orally.

Side Effects of Gotrin 0.125 MG Tablet 10

You might experience the following side effects after taking Gotrin 0.125 MG Tablet 10:

Nausea and vomiting
Abdominal pain and cramps
Headache
Dizziness
Elevated blood pressure: This medicine may cause a rise in your blood pressure levels.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Gotrin 0.125 MG Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some suggestions to manage common side effects:

Nausea and vomiting: Try taking Gotrin 0.125 MG Tablet 10 with food to mitigate these symptoms.
Elevated blood pressure: Monitor your blood pressure regularly while on this medication. If it rises significantly, consult your doctor immediately.

Gotrin 0.125 MG Tablet 10 contains methylergometrine (0.125 mg), and its activity in the body can be explained as follows:

Direct Uterine Action: Methylergometrine acts directly on the smooth muscles of the uterus. It increases the tone, rate and strength of rhythmic uterine contractions.
Reduced Blood Loss: By stimulating strong uterine contractions, methylergometrine compresses blood vessels which leads to reduced blood loss.
Uterotonic Effect: This effect helps in preventing and controlling postpartum haemorrhage by inducing strong contractions in the uterus.

Pregnancy

Gotrin 0.125 MG Tablet 10 is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Gotrin 0.125 MG Tablet 10 is contraindicated for breastfeeding/lactating women. Consult your doctor to understand the potential risks and benefits.

Alcohol

Caution is advised while taking Gotrin 0.125 MG Tablet 10 if you consume alcohol regularly. It is best to consult your doctor before taking this medicine.

Liver

Caution is advised while taking Gotrin 0.125 MG Tablet 10 in case of mild to moderate liver impairment. It is not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting Gotrin 0.125 MG Tablet 10. This medicine may affect liver function.

Kidney

Caution is advised before using Gotrin 0.125 MG Tablet 10 if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

Gotrin 0.125 MG Tablet 10 might cause dizziness. Therefore, caution is advised while driving or operating heavy machinery. Consult your doctor for more information.

Allergy

If you are allergic to methylergometrine or any other ingredients in Gotrin 0.125 MG Tablet 10, avoid taking it and consult your doctor.

Children

Gotrin 0.125 MG Tablet 10 is meant for adults and should not be given to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Gotrin 0.125 MG Tablet 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Older patients might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Interactions of Gotrin 0.125 MG Tablet 10

Drug-Drug Interactions

Gotrin 0.125 MG Tablet 10 interacts with the following medicines:

Ergot Alkaloids: Medicines like ergotamine may interact with Gotrin 0.125 MG Tablet 10, potentially leading to an amplified effect due to similar mechanisms of action.
Antivirals: Medicines like ritonavir may increase the blood concentration of Gotrin 0.125 MG Tablet 10, potentially heightening its effects and side effects.
Azole Antifungals: Antifungal medications like fluconazole and itraconazole may enhance the effects of Gotrin 0.125 MG Tablet 10 by reducing its breakdown in the body.
Antidepressants (MAO Inhibitors): These medications, such as phenelzine, interact with Gotrin 0.125 MG Tablet 10 and can increase the risk of hypertension.

Drug-Food Interactions

Gotrin 0.125 MG Tablet 10 does not have any known specific interactions with food items.

Drug-Disease Interactions

Gotrin 0.125 MG Tablet 10 interacts with the following diseases:

Hypertension and Preeclampsia: Gotrin 0.125 MG Tablet 10 can elevate blood pressure, thereby worsening these conditions.
Coronary Artery Disease: This medicine could potentially exacerbate heart-related symptoms in patients with this condition.
Peripheral Vascular Disease: The use of Gotrin 0.125 MG Tablet 10 may worsen symptoms in individuals suffering from this condition.
History of Stroke or Seizures: This medicine could potentially increase the risk of seizures or stroke in patients with a past history of these conditions.

Daily Dose

Take the daily recommended dose of Gotrin 0.125 MG Tablet 10 as advised by your doctor, taking into account the severity of your condition and how you respond to the medication. Make sure you stick to the prescribed dosage and avoid exceeding it without consulting your doctor.

Over Dose

In case of an accidental overdose of Gotrin 0.125 MG Tablet 10, you might experience symptoms such as nausea, vomiting, abdominal pain, or breathing difficulties. If these symptoms persist or worsen, make sure to inform your doctor.

Missed Dose

If you happen to miss a dose of Gotrin 0.125 MG Tablet 10, take it as soon as you remember. However, if it's nearly time for your next dose, simply skip the missed one and continue with your regular dosage schedule. Never adjust your dosage without consulting your doctor.

Store Gotrin 0.125 MG Tablet 10 at room temperature, ideally below 30°C.
Keep away from direct light and moisture to maintain its effectiveness.
Ensure it's out of reach of children and pets to prevent accidental ingestion.
Always check the expiry date before use and avoid taking expired medicine.

Try to maintain a balanced diet rich in iron to counteract potential blood loss, which this medicine helps manage. Iron-rich foods include leafy greens, lentils, and meat.
Since Gotrin 0.125 MG Tablet 10 is used after childbirth or abortion, rest is crucial for recovery. Aim for uninterrupted sleep and take short breaks throughout the day to help your body heal.

Fact Box

Drug Category	Uterotonic
Therapeutic Category	Ergot Alkaloid
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Postpartum Haemorrhage, Uterine Subinvolution

What is the main use of Gotrin 0.125 MG Tablet 10?

Gotrin 0.125 MG Tablet 10 is primarily used to prevent and control excess bleeding from the uterus after childbirth or abortion.

How does Gotrin 0.125 MG Tablet 10 work?

Gotrin 0.125 MG Tablet 10 increases the tone, rate, and strength of uterine contractions, reducing blood loss by compressing blood vessels in the uterus.

Can I take Gotrin 0.125 MG Tablet 10 while breastfeeding?

Gotrin 0.125 MG Tablet 10 should be avoided during breastfeeding as methylergometrine can pass into breast milk and may affect the baby.

Can I take other medicines while using Gotrin 0.125 MG Tablet 10?

Some medicines can interact with Gotrin 0.125 MG Tablet 10, affecting its effectiveness. Always consult your doctor before starting any new medication.

What should I do if I miss a dose of Gotrin 0.125 MG Tablet 10?

If you miss a dose, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one.

What are the common side effects of Gotrin 0.125 MG Tablet 10?

Common side effects include nausea, vomiting, abdominal pain, cramps, headache, dizziness and elevated blood pressure.

How should I store my Gotrin 0.125 MG Tablet 10?

Gotrin 0.125 MG Tablet 10s should be stored at room temperature (25°C), away from light and moisture and out of reach of children and pets.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

No. 328/329, 3rd Floor, Paradise Complex, Sayajigunj, Vadodara, Gujarat 390020

Country of origin: INDIA

References

Methergine®(methylergonovine maleate) . (N.d.). Fda.Gov. Retrieved August 28, 2024, from
https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/006035s078lbl.pdf
Unknown Unknown, U., Unknown. (n.d.). METHYLERGONOVINE b (Systemic) [Report]. https://simsrc.edu.in/pdf_df/M-drugs/methylergonovine.pdf
Methergine. (n.d.). https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=b1552d48-86f5-4184-810a-001e57e96c02&type=display
PubChem. (n.d.). Methylergonovine. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Methylergonovine
Methylergometrine: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00353

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