Hirepa 0.5 Tablet 10

Healing Pharma

Strip of 10 Units

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MRP ~~₹74~~

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Prescription required for this medicine

Store Below 30^o C

Composition

Repaglinide (0.5 Mg)

Strength:

2 MG 1 MG 0.5 MG

Hirepa 0.5 Tablet is an oral antidiabetic medication primarily prescribed to manage type 2 diabetes mellitus in adults. It belongs to the meglitinide class of medications.

This medication is used as an adjunct to diet and exercise when lifestyle modifications alone are insufficient to control blood sugar levels. It may also be prescribed in combination with metformin for better glycemic control.

Before starting this tablet, consult your doctor for the appropriate dosage and regimen suited to your health condition. Inform your doctor about any ongoing medications or underlying health conditions. If you experience any side effects, seek medical advice promptly.

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Hirepa 0.5 Tablet is used for:

Controlling blood sugar levels in type 2 diabetes mellitus
Reducing the risk of diabetes-related complications such as nerve damage, kidney issues, and cardiovascular diseases
Managing postprandial hyperglycemia (high blood sugar after meals)

Directions for Use of Hirepa 0.5 Tablet 10

Follow these steps while taking Hirepa 0.5 Tablet:

Take this tablet before meals, usually 15-30 minutes prior to eating.
Swallow the tablet whole with a glass of water; do not crush or chew it.
Do not take the medication if you skip a meal.
Always adhere to the prescribed dose and schedule provided by your doctor

Hirepa 0.5 Tablet is taken orally.

The common side effects of Hirepa 0.5 Tablet include:

Hypoglycemia (low blood sugar)
Headache
Dizziness
Nausea
Diarrhea

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing Hirepa 0.5 Tablet. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor. Here are some suggestions to manage the side effects.

Hypoglycemia: Consume glucose tablets, sugary drinks, or snacks immediately. Keep a carbohydrate source handy at all times.
Nausea: Take the tablet after a small snack if nausea persists.
Dizziness: Avoid standing up too quickly and ensure adequate hydration.

Hirepa 0.5 Tablet contains Repaglinide (0.5 mg), which works in the following ways:

It acts by stimulating the beta cells of the pancreas to produce more insulin. It binds to ATP-sensitive potassium channels on pancreatic cells, leading to insulin secretion in response to meals. This rapid insulin release helps prevent postprandial blood glucose spikes, making it effective in managing type 2 diabetes.

Pregnancy

Hirepa 0.5 Tablet should be used with caution during pregnancy. Consult your doctor before using this medication if you are pregnant or planning to conceive.

Breastfeeding

There is limited data on the safety of Repaglinide during breastfeeding. It is advisable to discuss alternative treatments with your doctor.

Alcohol

Alcohol consumption while taking Hirepa 0.5 Tablet may increase the risk of hypoglycemia. It is recommended to avoid or limit alcohol intake.

Liver

Patients with liver disease should use Hirepa 0.5 Tablet cautiously, as it is metabolised by the liver and may cause an increased risk of adverse effects.

Kidney

While Hirepa 0.5 Tablet is mainly eliminated via bile, patients with severe kidney impairment should consult their doctor before taking this medication.

Using Machines & Driving

If you experience dizziness or low blood sugar episodes, avoid driving or operating heavy machinery.

Allergy

If you have a known allergy to Repaglinide or other components of this medication, do not use Hirepa 0.5 Tablet. Seek medical help immediately if you develop breathing difficulties, rashes, or swelling.

Children

Hirepa 0.5 Tablet is not recommended for children below 18 years of age.

Older Patients

Elderly patients should use this medication under strict medical supervision due to the increased risk of hypoglycemia.

Drug-Drug Interactions

Hirepa 0.5 Tablet may interact with the following medications:

Lipid-regulating medications such as Gemfibrozil: The concomitant use may increase Repaglinide levels, leading to hypoglycemia.
Beta-blockers such as Atenolol: The concomitant use may mask hypoglycemia symptoms.
NSAIDs such as Aspirin: The concomitant use may increase the risk of low blood sugar.
Antifungal agents such as Ketoconazole and itraconazole: The concomitant use may affect metabolism.
Oral contraceptives: The concomitant use may alter blood glucose levels.

Drug-Food Interactions

Grapefruit juice may increase the levels of Repaglinide in the blood, leading to an increased risk of hypoglycemia.

Drug-Disease Interactions

Hirepa 0.5 Tablet may interact with the following conditions:

Liver disease: Increased risk of adverse effects due to impaired metabolism.
Severe infections, surgery, or trauma: A patient taking repaglinide when exposed to stress such as fever, trauma, infection, or surgery, may experience a loss of control of blood glucose.

Daily Dose

The doctor will determine the optimal dose based on your blood sugar levels, response to the treatment, and other medical conditions. The dosage may change based on individual factors such as age, the severity of the condition, and response to treatment.

Over Dose

An overdose of Hirepa 0.5 Tablet can cause severe hypoglycemia (low blood sugar), leading to symptoms such as excessive sweating, confusion, tremors, dizziness, and unconsciousness. If an overdose is suspected, consume sugar-containing foods or drinks and seek immediate medical attention.

Missed Dose

If you miss a dose, take it before your next meal. If it is almost time for your next scheduled dose, skip the missed one. Do not take two doses together to make up for a missed dose.

Store below 30°C in a dry place away from direct sunlight.
Keep out of reach of children.
Do not use after the expiration date mentioned on the package.

Follow a low-glycemic index diet rich in whole grains, vegetables, and lean proteins.
Avoid sugary foods and processed carbohydrates to prevent blood sugar spikes.
Engage in regular physical activity such as walking or light exercise.
Monitor blood sugar levels regularly to track treatment effectiveness.

Fact Box

Drug Category	Meglitinide class
Therapeutic Category	Oral hypoglycemic agent
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus

What is Hirepa 0.5 Tablet used for?

Hirepa 0.5 Tablet is used to control blood sugar levels in adults with type 2 diabetes.

How does Hirepa 0.5 Tablet work?

This tablet stimulates insulin release from the pancreas, helping lower blood sugar after meals.

What are the common side effects of Hirepa 0.5 Tablet?

The common side effects of this tablet include hypoglycemia, nausea, dizziness, and headache.

Can Hirepa 0.5 Tablet be taken with other diabetes medications?

Yes, it can be taken with other diabetic medications if recommended by a doctor.

Is Hirepa 0.5 Tablet safe during pregnancy and breastfeeding?

Consult your doctor before using this medication if you are pregnant or breastfeeding.

Last Updated On 10 Mar. 2025 | 2:05AM (IST)

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 6 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 11 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

Healing Pharma India Pvt Ltd ,411 4th Floor, B wing,Western Edge II,Behind Metro Mall, Western Express Hwy, Borivali East, Mumbai, Maharashtra 400066

Country of origin: INDIA

References

PRANDIN® (repaglinide) Tablets. (N.d.). Fda.Gov. Retrieved February 5, 2025, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020741s035lbl.pdf
Repaglinide Tablet (N.d.). Geneesmiddeleninformatiebank.Nl. Retrieved February 5, 2025, from https://www.geneesmiddeleninformatiebank.nl/smpc/h103352_smpc_en.pdf
AURO-REPAGLINIDE (repaglinide). (N.d.). Hres.Ca. Retrieved February 12, 2025, from https://pdf.hres.ca/dpd_pm/00034683.PDF

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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