Histafree 120 Tablet 10

Mankind Pharmaceuticals Ltd.

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Composition

Fexofenadine (120 Mg)

Histafree tablets are commonly used for the management of various allergy symptoms, including sneezing, itching, runny nose, and watery eyes. It is a widely prescribed medication that falls under the category of antihistamines.

The active ingredient in Histafree tablets acts by blocking the effects of histamine, a natural substance in the body that is responsible for allergic reactions. By inhibiting histamine activity, Histafree helps alleviate the discomfort and distress caused by allergies.

Histafree tablets are known for their efficacy in providing temporary relief from allergy symptoms, allowing individuals to enjoy a better quality of life. It is typically recommended for various allergic conditions, such as hay fever, allergic rhinitis, and allergic conjunctivitis. This tablet is available in different strengths and formulations, and the dosage may vary depending on the severity of the symptoms and the individual's response to the medication.

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Histafree is a commonly prescribed medication used for the treatment of various allergic conditions. Some of the key uses of Histafree include:

Allergic rhinitis: Histafree effectively alleviates the symptoms of allergic rhinitis, such as sneezing, itching, runny nose, and nasal congestion. It helps provide relief from seasonal or perennial allergies caused by triggers like pollen, dust mites, pet dander, or mold.
Urticaria: Histafree is beneficial in managing urticaria, commonly known as hives. It helps reduce itching, redness, and swelling associated with this allergic skin condition.
Allergic conjunctivitis: Histafree is used to treat allergic conjunctivitis, an inflammation of the conjunctiva (the clear tissue covering the front surface of the eye). It helps relieve symptoms like redness, itching, and watering of the eyes.
Allergic dermatitis: Histafree may be prescribed for allergic dermatitis, a skin condition characterised by itching, inflammation, and rashes. It helps alleviate the symptoms and provides relief from allergic skin reactions.
Allergic reactions: Histafree can be used to manage allergic reactions caused by various triggers, including insect bites or stings, medication allergies, or food allergies. It helps reduce itching, swelling, and other symptoms associated with these allergic reactions.

Directions for Use of Histafree 120 Tablet 10

Histafree tablets should be taken as your doctor recommends.
You can consume the tablet before or after a meal as instructed by the doctor.
Do not cut, break or chew the medicine.
Take it at a fixed time for the best results. .

Histafree tablets should be administered orally.

Histafree tablets are well-tolerated. But you may experience minor side effects, as mentioned below.

Headache: Some individuals may experience headaches while taking Histafree.
Drowsiness: Although it is generally considered a non-drowsy antihistamine, some people may still experience mild drowsiness. However, this side effect is less common compared to first-generation antihistamines.
Nausea: It can occasionally cause nausea, resulting in a feeling of discomfort or an urge to vomit.
Dry mouth: Dry mouth is a common side effect of many antihistamines, including Histafree. It can manifest as a decrease in saliva production, leading to a dry, sticky sensation in the mouth.
Gastrointestinal upset: Some individuals may experience gastrointestinal disturbances such as stomach pain, diarrhoea, or constipation while taking Histafree.
Fatigue: Although Histafree is generally associated with lower levels of sedation, some people may experience mild fatigue or tiredness as a side effect.
Dizziness: In rare cases, it can cause dizziness, resulting in a feeling of lightheadedness or unsteadiness.
Allergic reactions: While rare, some individuals may develop an allergic reaction to fexofenadine. Symptoms of an allergic reaction can include hives, itching, rash, swelling (especially on the face, lips, tongue, or throat), and difficulty breathing.

Managing the Side Effects:

The side effects can be managed by the following ways:

Headache: Applying a cool compress on the forehead or neck may help reduce headaches. Staying hydrated and avoiding triggers, such as stress or certain foods, may also be helpful.
Nausea: Histafree can cause nausea in some people, especially when standing up quickly. Avoid sudden changes in position, and rise slowly from a seated or lying position. If you experience severe nausea, talk to your healthcare provider.
Dry mouth: To manage dry mouth while taking this medication, it is important to stay hydrated by drinking plenty of water throughout the day.
Gastrointestinal upset: To reduce gastrointestinal upset, taking the medication with food can help reduce stomach irritation. Avoiding spicy, greasy, or acidic foods that can exacerbate gastrointestinal symptoms may also be beneficial.
Fatigue: If experiencing fatigue while taking Histafree, it is advisable to ensure adequate sleep and maintain a balanced and nutritious diet.
Dizziness: Histafree causes dizziness, it is recommended to avoid sudden changes in body position, such as standing up quickly from a sitting or lying down position.
Allergic reactions: Allergic reactions to Histafree are rare but can be serious. If you experience symptoms like hives, itching, swelling, or difficulty breathing, seek immediate medical assistance.

Histafree tablet is a potent anti-allergic medicine containing fexofenadine. It is a non-drowsy antihistamine, meaning it does not cause drowsiness or sedation in most people.

Fexofenadine binds to the histamine H1 receptors in various tissues, including the respiratory tract, skin, and blood vessels.

By blocking the H1 receptors, Histafree inhibits the binding of histamine to these receptors, preventing or reducing the allergic response. This helps alleviate symptoms associated with allergies, such as sneezing, itching, runny nose, and watery eyes. Histafree also helps minimise the release of other inflammatory substances, further reducing the allergic response.

Pregnancy

Histafree should be used cautiously during pregnancy, especially during the first trimester. If you are pregnant or planning for pregnancy, talk to your healthcare provider before taking this medication.

Breastfeeding

It is unknown if Histafree is excreted into breast milk, so it should be used cautiously during breastfeeding. If you are breastfeeding, talk to your healthcare provider before taking this medication.

Alcohol

It is advisable to avoid alcohol while taking this tablet as it can increase the risk of dizziness and drowsiness.

Liver

Individuals with liver impairment should use Histafree cautiously, as the medication may be metabolised more slowly. A healthcare professional can evaluate liver function and determine if dose adjustments or alternative treatments are necessary.

Kidney

People with kidney impairment should exercise caution when taking this tablet, as the medication's elimination may be affected. A healthcare professional can assess kidney function, adjust the dosage or suggest alternative treatments if required.

Using Machines & Driving

Although Histafree is generally considered non-drowsy, some individuals may experience mild drowsiness. Caution should be exercised when operating machinery or driving a vehicle until the individual knows how they respond to the medication.

Allergy

Inform your healthcare professional about any known allergies to fexofenadine or other antihistamines before starting Histafree. They can evaluate the risks and suggest alternative treatment options if necessary.

Children

Histafree can be used in children; however, it is important to consult a healthcare professional for appropriate dosage adjustments based on their age and weight. Careful monitoring is recommended to ensure the medication's safety and effectiveness in paediatric patients.

Older Patients

Older patients may be more susceptible to the side effects of Histafree, especially nausea. A lower dose may be required in some cases. If you are an older patient, talk to your healthcare provider before taking this medication.

Drug-Drug Interactions

Histafree can interact with drugs, including:

Ketoconazole
Erythromycin
Fluvoxamine
The combination of Histafree with other antihistamines, sedatives, tranquillisers, or other medications that can cause drowsiness may also increase the risk of dizziness and drowsiness.
Also, it interacts with certain heart medications such as beta-blockers and calcium channel blockers, and it is important to inform your healthcare provider if you are taking these medications.

Drug-Food Interactions

Food does not affect the absorption of Histafree, but:

Grapefruit juice may increase the level of fexofenadine in the blood, leading to an increased risk of side effects.

Drug-Disease Interactions

Patients with liver or kidney disease may require a lower dose of Histafree due to the risk of accumulation of the medication in the body, which can increase the risk of side effects.
Individuals with phenylketonuria (PKU) should be aware that the orally disintegrating tablet form of Histafree contains phenylalanine, which can be harmful to individuals with this condition.
It may worsen symptoms in patients with asthma and should be used with caution in such patients.

Daily Dose

The recommended daily dose of Histafree is one tablet taken once a day, with or without food or as directed by your doctor. The dosage may change based on individual factors like the severity of the condition and response to treatment. It is essential to follow the suggested dosage and not exceed it without consulting your doctor.

Over Dose

If you or someone else takes an excessive Histafree tablet by accident, it is essential to take immediate medical attention from your doctor or nearby hospital. Symptoms of an overdose may include drowsiness, dry mouth, headache, nausea, and vomiting. In case of an overdose, seek medical attention immediately.

Missed Dose

If you miss a dose of Histafree, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed dose. It is important to take the medication as your healthcare provider directs to ensure the best possible results.

Store it at room temperature (15-25ºC).
Keep it away from heat and moisture.
Don't use this medicine after the expiry date has passed.
Keep this medicine away from children.

If your stomach is sensitive to Histafree medicine, please use it with your meal to avoid any stomach discomfort.
Follow a rich diet that includes leafy vegetables and the required amount of protein.
Stay hydrated by drinking plenty of water.
Avoid alcohol.
It is better to consume the tablet at night before sleep. But if your doctor suggests consuming it in the morning, you can take it after breakfast too.

Do not exceed the medicine dosage.
Consume Histafree as directed by a medical professional.
Never take the medication on an empty stomach.
Don't break, chew, crush or bite the tablet.
If you missed a dose, consume it soon. But if it's time for the next dose, skip your previous Histafree dosage and follow the next one.
In case of severe side effects, please consult your medical professional.

Fact Box

Drug Category	Antihistamine and leukotriene receptor antagonist
Therapeutic Category	Anti-allergic
Available Dosage Types	Tablets and orally disintegrating tablets
Habit Forming	No
Ailment	Primarily used to treat symptoms of allergic rhinitis and chronic idiopathic urticaria.

Is Histafree tablet antibiotic?

No, Histafree isn't considered an antibiotic medicine. It is an anti-allergic medicine that can relieve allergic rhinitis categorised by watery eyes, blocked or runny nose, sneezing, hives or skin rash, and itching.

What is the drug name of Histafree?

The drug name of Histafree is fexofenadine. Fexofenadine is the active ingredient in Histafree, which is an antihistamine medication used to relieve allergy symptoms such as sneezing, itching, runny nose, and watery eyes.

What is the age limit for taking Histafree?

Histafree tablets are for use by adults and children above 12 years of age as they contain fexofenadine, an antihistamine. However, it is recommended to avoid buying this medicine for children below 12 years unless recommended by a doctor. This medicine provides relief from various allergies such as hay fever symptoms, seasonal allergic rhinitis, and other similar conditions.

Does Histafree Clear Mucus?

Histafree (fexofenadine) primarily relieves allergy symptoms like sneezing and itching, but it is not specifically designed to clear mucus. Consult a healthcare professional for mucus-related concerns.

Is Histafree Safe?

Histafree is usually well-tolerated. But in a few conditions, patients may experience minor side effects like headache, drowsiness, diarrhoea, skin rash, vomiting, nausea, fever, and dizziness. Although most side effects don't require medical attention, it's better to consult a doctor if the conditions worsen.

Last Updated On 08 Feb. 2024 | 1:14PM (IST)

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 5 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 10 years

MBBS, DNB (OBGY)

Check out Editorial Policy

References

Sharma A, Shankar R, Tyagi LK, et al. Levocetirizine: A Review of Its Use in Allergic Rhinitis and Skin Allergies. Indian J Pharm Sci. 2017;79(2):212-221. doi:10.4172/pharmaceutical-sciences.1000249
Vaidya V, Singh H, Agrawal VK, et al. Safety and efficacy of levocetirizine oral drops in children with allergic rhinitis: an open-label, prospective, multicenter study. Indian J Pediatr. 2013;80(12):996-1000. doi:10.1007/s12098-013-1091-6
Simons FE, Simons KJ. Histamine and H1-antihistamines: celebrating a century of progress. J Allergy Clin Immunol. 2011;128(6):1139-1150.e4. doi:10.1016/j.jaci.2011.10.025
Church MK, Maurer M, Simons FE, Bindslev-Jensen C, van Cauwenberge P, Bousquet J. Risk of first-generation H(1)-antihistamines: a GA(2)LEN position paper. Allergy. 2010;65(4):459-466. doi:10.1111/j.1398-9995.2009.02320.x
U.S. National Library of Medicine. Levocetirizine. MedlinePlus. [Updated on September 15, 2021]. [Accessed on April 21, 2023]. https://medlineplus.gov/druginfo/meds/a608026.html

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