Inapure 10 Mg Tablet Er 10

Inapure Er 10 Tablet 10

Sun Pharma Laboratories Ltd.

Strip of 10 Units

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MRP ~~₹407.00~~

₹333.74

₹40.70/Units

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Composition

Ivabradine (10 Mg)

Strength:

10 MG 15 MG

Inapure ER 10 Tablet is primarily used to manage symptoms of stable angina pectoris (chest pain) and chronic heart failure. This medication belongs to a group of medicines known as selective heart rate reducing agents.

In addition to these main uses, this medicine is also indicated for the symptomatic management of stable angina pectoris in adults who cannot take beta blockers and for the treatment of chronic heart failure with systolic dysfunction in patients with a fast heart rate (≥ 75 bpm), where it is used alongside standard therapy. By reducing the heart rate, it decreases the heart's demand for oxygen and improves blood flow to the heart muscle.

This medicine should be taken orally as directed by your doctor. It's crucial to inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you notice any side effects while on this medication, inform your doctor immediately. Remember to continue taking the medicine for the duration prescribed by your doctor for optimal results.

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Inapure ER 10 Tablet is used for the following:

Helping to manage stable angina pectoris, a type of chest pain
Assisting in the management of chronic heart failure of New York Heart Association (NYHA) class II-IV with systolic dysfunction, when the patient's heart rate is ≥ 75 bpm
These conditions are managed with Inapure ER 10 Tablet alongside standard therapy. This medicine is particularly useful for patients who can't take beta blockers due to intolerance or contraindications.

Directions for Use of Inapure Er 10 Tablet 10

Here's how you should take Inapure ER 10 Tablet:

Swallow the tablet whole with a glass of water.
Don't crush or chew the tablet.
The medicine should be taken around meal times.

Inapure ER 10 Tablet is taken orally.

Inapure ER 10 Tablet may have the following side effects:

Luminous phenomena (phosphenes): This refers to an enhanced brightness in a limited area of your vision. It's usually triggered by sudden changes in light intensity.
Blurred vision
Bradycardia: This is a condition where your heart rate is slower than normal.
Headache
Dizziness
Vertigo: This is a sensation of feeling off-balance, like you're spinning or your surroundings are spinning.
Atrial fibrillation: This is an irregular and often rapid heart rate that can increase your risk of stroke.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Inapure ER 10 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some guidelines for managing common side effects:

Luminous phenomena (phosphenes): Try avoiding sudden changes in light intensity as it might trigger this effect.
Bradycardia: Monitor your heart rate regularly and consult your doctor if it falls below the normal range.

Inapure ER 10 Tablet contains ivabradine (10 mg), which works on your body in the following ways:

Reduction in Heart Rate: Ivabradine selectively inhibits the cardiac pacemaker If the current in the sinoatrial node, the heart's natural pacemaker. This leads to a reduction in the heart rate both when you are at rest and during exercise.
Decrease in Oxygen Consumption: By reducing the heart rate, ivabradine decreases the amount of oxygen your heart needs to function. This can help manage symptoms of stable angina pectoris and chronic heart failure.
Improvement in Diastolic Perfusion Time: This is the time during which blood flow to the heart muscle is increased, allowing it to receive more oxygen and nutrients. Ivabradine helps improve this time, which can be beneficial in managing heart conditions.

Pregnancy

Caution is advised while taking Inapure ER 10 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, it is unknown whether ivabradine is excreted in human milk. As a safety measure, discuss with your doctor the risks and benefits before taking this medicine.

Alcohol

There's no specific information available on interactions between Inapure ER 10 Tablet and alcohol. As a precaution, it's wise to limit alcohol consumption while taking this medicine.

Liver

If you have liver problems, caution is advised when taking Inapure ER 10 Tablet. This medicine may especially affect those with severe liver diseases. Consult with your doctor before starting this medication.

Kidney

In case of severe kidney insufficiency, Inapure ER 10 Tablet should be used with care. Consult your doctor before starting this medication if you have any kidney problems.

Using Machines & Driving

As some side effects of Inapure ER 10 Tablet include luminous phenomena and blurred vision, caution is advised while driving or operating heavy machinery.

Allergy

Inapure ER 10 Tablet is contraindicated for those who are hypersensitive to ivabradine or any of the excipients in the tablet. If you have a history of allergies, it's important to discuss it with your doctor before starting this medicine.

Children

Inapure ER 10 Tablet is not recommended for use in children under the age of 18 years. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Inapure ER 10 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Inapure ER 10 Tablet interacts with the following medicines:

Antifungals: Medicines like ketoconazole and itraconazole can increase the level of ivabradine in your blood, possibly leading to lower heart rate (bradycardia).
Antihistamine: Medications such as rifampicin can decrease the effectiveness of Inapure ER 10 Tablet.
Calcium Channel Blockers: Using medicines that reduce heart rate, like verapamil or diltiazem, is not advised when taking Inapure ER 10 Tablet.

Drug-Food Interactions

Drug-Disease Interactions

Inapure ER 10 Tablet interacts with the following diseases:

Severe Hepatic Insufficiency: This medicine should not be used if you have severe liver problems as it could exacerbate your condition.
Cardiogenic Shock: If you have a severe heart problem where your heart cannot supply enough blood to your body, avoid using this medicine.
Unstable or Acute Heart Failure: For those with unstable or sudden worsening of heart failure, this medicine is not recommended.
Chronic Retinal Diseases: Patients with chronic eye diseases should use this medicine cautiously due to potential side effects related to vision.

Daily Dose

Your daily dose of Inapure ER 10 Tablet should be as your doctor prescribes. The dosage may vary based on your condition and response to the medicine. It's crucial not to alter your dose without your doctor's advice.

Over Dose

An accidental overdose of Inapure ER 10 Tablet can cause symptoms similar to its side effects. If you suspect an overdose, inform your doctor, but avoid panicking or rushing unnecessarily.

Missed Dose

If you forget to take your Inapure ER 10 Tablet, do so as soon as you remember. But if it's nearly time for the next dose, skip the missed one and resume your regular schedule. Never increase your medicine dosage without consulting your doctor.

Keep Inapure ER 10 Tablet in its original package to protect it from light and moisture.
Store at room temperature.
Avoid exposure to excess heat or cold.
Make sure the medicine is out of sight and reach of children.
Always check the expiry date on the pack before use.

If you have been prescribed Inapure ER 10 Tablet for angina or heart failure, try to maintain a low-sodium diet. This can help manage fluid build-up and decrease the workload on your heart.
Regular, moderate-intensity exercise such as walking or cycling can help strengthen your heart. However, always consult your doctor before starting any new exercise regime.

Fact Box

Drug Category	Heart Rate Reducer
Therapeutic Category	Cardiac Medicine
Available Dosage Types	Tablet ER
Habit Forming	No
Ailment	Stable Angina Pectoris, Chronic Heart Failure

What is Inapure ER 10 Tablet used for?

It's used to manage symptoms of stable chest pain (angina) and chronic heart failure in adults, especially those who can't take beta blockers.

How does Inapure ER 10 Tablet work?

The medicine works by selectively slowing down the heart rate, reducing the heart's oxygen demand and improving oxygen supply to the heart muscle.

How should I take Inapure ER 10 Tablet?

You should swallow the tablet whole with water, ideally at meal times. Do not crush or chew it. Always follow your doctor's instructions.

What are the common side effects of Inapure ER 10 Tablet?

Common side effects include perceived brightness in vision (phosphenes), blurred vision, and slow heartbeat (bradycardia). These are usually mild and temporary.

Can I drive or operate machinery while taking Inapure ER 10 Tablet?

If you experience luminous phenomena (enhanced brightness in vision), avoid driving or operating machinery. Always consult your doctor for advice.

Is Inapure ER 10 Tablet safe during pregnancy and breastfeeding?

Inapure ER 10 Tablet is unsafe to use during pregnancy or breastfeeding, it's recommended not to take this medicine during these periods without consulting your doctor.

Are there any precautions I need to take while using Inapure ER 10 Tablet?

Yes, if you have a low resting heart rate, severe liver problems, certain heart conditions or are taking specific other medicines, you should consult your doctor before using this medicine.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

SUN HOUSE CTS No. 201, 201, Western Express Hwy, Ram Nagar, Goregaon, Mumbai, Maharashtra 400063

Country of origin: INDIA

References

Amgen. (2015). HIGHLIGHTS OF PRESCRIBING INFORMATION [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/209964lbl.pdf
VA Pharmacy Benefits Management Services, Medical Advisory Panel, and VISN Pharmacist Executives. (2015). Ivabradine Drug Monograph. https://www.pbm.va.gov/PBM/clinicalguidance/drugmonographs/Ivabradine_CORLANOR_Monograph.pdf
Ivabradine: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB09083
Fala, L. (2016, March 1). Corlanor (Ivabradine), First HCN Channel Blocker, FDA Approved for the Treatment of Patients with Heart Failure. PubMed Central (PMC). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013853/
Tse, S., & Mazzola, N. (2015, December 1). Ivabradine (Corlanor) for heart failure: the first selective and specific if inhibitor. PubMed Central (PMC). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671466/

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