Kinpride Sr Tablet 10

Dr. Reddys Laboratories Ltd

Strip of 10 Units

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MRP ~~₹315.75~~

₹252.6

₹31.57/Units

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Composition

Cinitapride (3 Mg)

Kinpride-SR Tablet is primarily employed to manage gastrointestinal motility disorders. This medicine falls within the category of prokinetic agents, a class of medicines designed to increase muscle movements in your digestive tract.

In addition to its major use, this tablet is also beneficial for managing conditions such as gastroesophageal reflux disease (GERD) and functional dyspepsia. GERD involves chronic irritation of the food pipe lining due to stomach acid or bile, whereas functional dyspepsia is a persistent upper abdominal discomfort with no clear physical cause.

It's crucial that you take this medicine as directed by your doctor. Prior to commencing this medication, inform your doctor about any pre-existing conditions or current medications you might be on. If you encounter any side effects while on this medicine, don't hesitate to notify your doctor immediately. For optimal results, continue taking the medicine for the full duration prescribed by your doctor.

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Kinpride-SR Tablet is used for managing the following conditions:

Gastroesophageal Reflux Disease (GERD): A chronic condition where stomach acid or bile irritates the lining of the food pipe.
Functional Dyspepsia: Persistent discomfort or pain in the upper abdomen with no obvious physical cause.

Directions for Use of Kinpride Sr Tablet 10

Taking Kinpride-SR Tablet is simple. Just follow these instructions:

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet as it will disrupt its extended-release properties.
Ensure you take the tablet about 15 to 30 minutes before a meal for maximum effectiveness.
Always consult your doctor if you have any doubts about how to take this medicine.

Kinpride-SR Tablet is taken orally.

Taking Kinpride-SR Tablet might lead to the following side effects:

Headache
Abdominal Pain
Nausea
Diarrhoea
Drowsiness
Muscle Spasms: This means sudden, involuntary muscle contractions.
Galactorrhea: This refers to a condition where milk production occurs unrelated to nursing.
Facial Oedema: This means swelling caused by fluid accumulation in the facial tissues.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Kinpride-SR Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some guidelines for managing common side effects:

Diarrhoea: Try taking Kinpride-SR Tablet with food or milk.
Nausea: You might find it helpful to take this medicine after meals to lessen this effect.

Kinpride-SR Tablet contains Cinitapride (3 mg), which impacts your body in the following ways:

Selective 5-HT4 receptor agonist: Cinitapride selectively stimulates 5-HT4 receptors in your body. This action triggers the release of a chemical called acetylcholine.
5-HT2 receptor antagonist: In addition to its agonistic action on 5-HT4 receptors, Cinitapride also blocks 5-HT2 receptors. This dual action leads to an increase in gastrointestinal motility and gastric emptying.
Reduction of oesophagal reflux: By enhancing oesophagal and gastric peristalsis (wave-like muscle movements), it reduces reflux of stomach contents into the food pipe.
Relief from dyspeptic symptoms: The increased motility and gastric emptying also help to relieve symptoms associated with indigestion, improving digestion.

Pregnancy

Kinpride-SR Tablet is advised to be avoided during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Kinpride-SR Tablet is contraindicated for breastfeeding women. Consult your doctor to understand the potential risks and benefits.

Alcohol

Drinking alcohol while taking Kinpride-SR Tablet may increase the risk of side effects like drowsiness. It's wise to limit or avoid alcohol while on this medicine.

Liver

Caution is advised while taking Kinpride-SR Tablet in case of mild to moderate liver impairment. It is not recommended for severe liver diseases. If you have liver health issues, discuss them with your doctor before starting this medicine.

Kidney

If you have a history of kidney health problems, it's a good idea to consult your doctor before taking Kinpride-SR Tablet. Your doctor will guide you based on your health status.

Using Machines & Driving

Kinpride-SR Tablet may cause drowsiness. Therefore, if you are driving or operating machinery, ensure you're aware of how this medicine affects you.

Allergy

If you are allergic to Cinitapride or any other components of Kinpride-SR Tablet, avoid using it. Always inform your doctor about your allergies before starting this medicine.

Children

Kinpride-SR Tablet is not recommended for children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Kinpride-SR Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years old due to potential liver and kidney issues.

Drug-Drug Interactions

Kinpride-SR Tablet interacts with the following medicines:

Cytochrome P450 inhibitors and inducers: Medicines like erythromycin or rifampicin may interact with Kinpride-SR Tablet, potentially affecting its metabolism in the liver.
Anticholinergics: Medicines such as atropine or hyoscine can counteract the effects of Kinpride-SR Tablet on the gastrointestinal tract.
Opioids: Medicines like morphine and codeine can reduce the effectiveness of Kinpride-SR Tablet by slowing down gut movement.
Muscle relaxants: Medicines like baclofen can negate the prokinetic effects of Kinpride-SR Tablet.

Drug-Food Interactions

Kinpride-SR Tablet has known interaction with grapefruit juice which can increase its bioavailability.

Drug-Disease Interactions

Kinpride-SR Tablet interacts with the following diseases:

Epilepsy: Patients with epilepsy may experience increased seizure frequency due to this medicine.
Severe liver or kidney disease: Kinpride-SR Tablet may accumulate in the body in these conditions, leading to side effects.
Diabetes Mellitus: This medicine may affect blood glucose levels, requiring closer monitoring.
Cardiovascular disorders: Caution is advised due to potential effects on heart rhythm.

Daily Dose

The daily dose of Kinpride-SR Tablet should be taken as directed by your doctor. The dosage may vary based on factors such as the severity of your condition and how you respond to the medicine. Always stick to the dosage prescribed by your doctor and avoid exceeding it without a consultation.

Over Dose

If you accidentally take more than the prescribed dose of Kinpride-SR Tablet, you could experience symptoms like severe nausea, abdominal cramps, and diarrhoea. In such cases, consult your doctor for advice.

Missed Dose

If you forget to take a dose of Kinpride-SR Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Remember not to increase your dosage without consulting your doctor.

Keep your Kinpride-SR Tablet in a dry place, ideally below 30°C.
Shield the medicine from light and moisture to maintain its effectiveness.
Always ensure the tablet is out of reach of children, to prevent accidental ingestion.
Check the expiry date before use; do not consume if the product has expired.

For managing gastroesophageal reflux disease (GERD), try reducing your intake of spicy and fatty foods. These can cause more stomach acid, leading to acid reflux.
If you have functional dyspepsia (indigestion), consider eating smaller meals more frequently. Overeating can strain your digestive system, worsening discomfort and slow digestion.

Fact Box

Drug Category	Serotonergic Agent
Therapeutic Category	Gastroprokinetic
Available Dosage Types	Extended-Release Tablet
Habit Forming	No
Ailment	GERD, Functional Dyspepsia

What is the Kinpride-SR Tablet used to manage?

Kinpride-SR Tablet is used to manage gastroesophageal reflux disease and functional dyspepsia, which are common digestive disorders.

How does Kinpride-SR Tablet work?

Kinpride-SR Tablet increases stomach and intestine movements, helping food move more easily through the stomach, reducing heartburn and indigestion.

How should I take the Kinpride-SR Tablet?

Take the Kinpride-SR Tablet orally, 15-30 minutes before a meal, and swallow it whole without crushing or chewing.

What are the common side effects of Kinpride-SR Tablet?

Common side effects include headache, abdominal pain, nausea, diarrhoea and drowsiness. Most side effects are mild and temporary.

Can I take Kinpride-SR Tablet if I am pregnant or breastfeeding?

Kinpride-SR Tablet is advised to be avoided during pregnancy and lactation. If you are pregnant, planning to conceive, or breastfeeding make sure to discuss this with your doctor before starting this medicine.

Can Kinpride-SR Tablet interact with other medications?

Yes, it can interact with certain medications including anticholinergics, opioids, muscle relaxants, sedatives, and antidepressants. Consult your doctor about all medications you're currently taking.

How should I store my Kinpride-SR Tablets?

Store your Kinpride-SR Tablets below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 9 years

Doctor of Medicine

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 9 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Bigshare Services Pvt. Ltd. 306, Right Wing, 3rd Floor Amrutha Ville, Opp.Yash Hyderabad - 500082 Telangana

Country of origin: INDIA

References

Cinita (Cinitapride) tablets 1mg (Package Insert No. EX00-200007539). (2000). [Tablets 1mg]. https://getzpharma.com/wp-content/uploads/2016/07/Cinita-Tab-Leaflet-Export-GA.pdf
Cinitapride: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB08810
PubChem. (n.d.). Cinitapride. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Cinitapride
UNII - R8I97I2L24. (n.d.). https://precision.fda.gov/uniisearch/srs/unii/R8I97I2L24
Du, Y., Su, T., Song, X., Gao, J., Zou, D., Zuo, C., Xie, W., Wang, B., Zhang, Z., Xu, J., Tian, D., Luo, H., Zhang, Z., Wang, S., Chen, J., Guo, J., Gong, L., Ding, Y., & Li, Z. (2014). Efficacy and safety of cinitapride in the treatment of mild to moderate postprandial distress syndrome–predominant functional dyspepsia. Journal of Clinical Gastroenterology, 48(4), 328–335. https://doi.org/10.1097/mcg.0000000000000033

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