Korandil 5 Tablet 10

Korandil 5 Tablet is used for the following:

• Prophylaxis and management of angina pectoris

• Prevention of angina attacks triggered by physical exertion or emotional stress

• Reduction in the frequency and severity of acute anginal episodes

• Improvement in exercise tolerance and capacity in patients with angina

• Minimization of reliance on sublingual nitrates for immediate relief from angina

Follow these instructions while taking Korandil 5 Tablet:

• This medicine should be taken orally, as directed by your doctor.

• Swallow the tablet whole with a glass of water, either with or without food.

• Try to take this medication at the same times each day to maintain consistent blood levels.

• Abrupt discontinuation should be avoided as it may worsen angina symptoms. Any changes in dosage or cessation of treatment should be done under medical supervision.

Korandil 5 Tablet is taken orally.

Korandil 5 Tablet contains nicorandil (5 mg) working in the body through two distinct mechanisms:

• ATP-sensitive Potassium Channels Activation: Nicorandil enhances the opening of ATP-sensitive potassium channels in vascular smooth muscles. This leads to hyperpolarization and relaxation of these muscles, thereby decreasing peripheral resistance and the load on the heart.

• Nitrate-like Effect: Nicorandil acts similar to nitrates, releasing nitric oxide (NO). This stimulates an enzyme named guanylate cyclase which boosts cGMP levels, triggering vasodilation of coronary arteries and systemic veins. Consequently, vasodilation reduces preload, while coronary dilation improves blood supply to the heart muscle.

  The combined effect of these mechanisms assists in lowering cardiac workload and oxygen demand while increasing oxygen supply to the heart muscle, offering relief from anginal pain.

1. Ensure Korandil 5 Tablet is stored at a room temperature between 15-30°C.

2. Keep it protected from direct light and moisture to maintain its effectiveness.

3. Always store the product out of sight and reach of children for their safety.

4. It's essential to use the medicine before its expiry date printed on the pack.

• If you're managing angina, include physical activity in your routine. Regular, moderate exercise like walking or swimming can help strengthen your heart and improve blood flow. Remember to consult your doctor before starting any new exercise regimen.

• Incorporate heart-healthy foods in your diet. Opt for whole grains, lean proteins, fruits, and vegetables.

• Limit high-fat and high-sodium foods to manage angina effectively.