Levomac 500 MG Infusion 100 ML

Macleods Pharmaceuticals Pvt.ltd

Pack of 100 ML

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Composition

Levofloxacin (500 Mg)

Levomac I.V. Infusion is primarily used to manage various bacterial infections in adults. This medicine belongs to a class of medications known as fluoroquinolone antibiotics.

Apart from the main use, it also helps manage other conditions such as pneumonia, urinary tract infections (UTIs), sinusitis, prostatitis, skin and soft tissue infections, and post-exposure inhalational anthrax. It's sometimes used off-label for bronchitis, endocarditis, certain STDs, salmonella, shigella, and tuberculosis.

Levomac I.V. Infusion is utilised for managing the following conditions:

Pneumonia, including cases acquired in hospitals and those associated with ventilators
Complicated and uncomplicated urinary tract infections, including kidney infections or pyelonephritis
Acute bacterial sinusitis is an inflammation of the sinuses caused by bacteria
Chronic bacterial prostatitis, a long-term bacterial infection of the prostate gland
Skin and soft tissue infections caused by bacteria
Inhalational anthrax post-exposure, a serious bacterial illness
Plague, a severe and often deadly disease caused by Yersinia pestis bacteria.

Directions for Use of Levomac 500 MG Infusion 100 ML

Administering Levomac I.V. Infusion involves the following steps:

A healthcare professional will administer this medicine intravenously.
It's important to ensure that it is infused slowly to minimise side effects.
Remember that dosage adjustments may be required if you have kidney impairment.
For specific advice on how to use Levomac I.V. Infusion, it's best to consult your doctor.

Levomac I.V. Infusion is administered intravenously.

Side Effects of Levomac 500 MG Infusion 100 ML

Levomac I.V. Infusion may have the following common side effects:

Nausea
Diarrhoea
Headache
Insomnia: This medicine might cause difficulty in falling asleep or staying asleep.
Dizziness
Injection site reactions

Managing the Side Effects:

Most side effects are temporary and generally harmless, which are resolved by discontinuing the use of Levomac I.V. Infusion. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Try to take your meals regularly and avoid spicy food.
Insomnia: Consider administering this medicine in the morning to lessen its effect on your sleep.

How Levomac 500 MG Infusion 100 ML Works?

Levomac I.V. Infusion contains two active ingredients:

Levofloxacin (500 mg): As a fluoroquinolone antibiotic, levofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV enzymes in the body. These enzymes are crucial for bacterial DNA to unwind and duplicate, which are necessary steps for bacteria survival and reproduction. By disrupting these functions, levofloxacin effectively causes bacterial cell death.
Dextrose Anhydrous (5 gm): This is a type of sugar that provides an energy source for the body. It's included in the infusion to help replenish lost nutrients and electrolytes during illness or treatment.

Pregnancy

Levomac I.V. Infusion should be avoided during pregnancy. If you are pregnant or planning to conceive, please consult your doctor to understand the potential risks and benefits.

Breastfeeding

This medicine may pass into breast milk and could potentially harm nursing infants. It is important to consult your doctor if you are breastfeeding or planning to do so.

Alcohol

The effects of Levomac I.V. Infusion when consumed with alcohol are not well understood. Caution is advised, and it is best to consult your doctor before administering this medicine with alcohol.

Liver

If you have liver health issues, you should be cautious while using Levomac I.V. Infusion as it may affect liver function. Please consult your doctor who will guide you on the usage of this medicine based on your health status.

Kidney

Caution is advised when using Levomac I.V. Infusion if you have a history of kidney problems. Your doctor will provide guidance based on your health status.

Using Machines & Driving

The medicine may cause dizziness or other side effects that could affect your ability to drive or operate machinery. It's advisable to avoid such activities until you know how this medicine affects you.

Allergy

Avoid Levomac I.V. Infusion if you have known hypersensitivity to levofloxacin or any other component of the formulation.

Children

Levomac I.V. Infusion is primarily meant for adults and should be given to children only under medical supervision. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients may be more susceptible to side effects, so caution is advised while taking Levomac I.V. Infusion. Consult your doctor who will guide you based on your health status.

Interactions of Levomac 500 MG Infusion 100 ML

Drug-Drug Interactions

Levomac I.V. Infusion interacts with the following medicines:

Antacids and Sucralfate: These medications, like aluminium hydroxide and magnesium hydroxide, can reduce the effectiveness of Levomac I.V. Infusion by binding to levofloxacin and preventing its absorption.
Nonsteroidal Anti-Inflammatory Medicines (NSAIDs): Medicines such as ibuprofen and naproxen can increase the risk of central nervous system effects when taken with Levomac I.V. Infusion.
Antidiabetic Agents: These medications, including metformin and insulin, might require dose adjustment when used with Levomac I.V. Infusion due to potential changes in blood glucose levels.
QT-Prolonging Medications: Medicines like amiodarone or certain antipsychotics might increase the risk of QT interval prolongation when taken with Levomac I.V. Infusion.

Drug-Food Interactions

Levomac I.V. Infusion interacts with the following foods:

Dairy Products: Foods high in calcium, such as milk or cheese, can interfere with the absorption of levofloxacin in Levomac I.V. Infusion.

Drug-Disease Interactions

Levomac I.V. Infusion interacts with the following diseases:

CNS Disorders: Conditions like epilepsy which may predispose to seizures can be aggravated by levofloxacin.
Diabetes: As it may affect blood glucose levels, close monitoring is needed when using this medicine.
Renal Impairment: Lower doses are required for patients with kidney disease to avoid toxicity due to decreased medicine clearance.

Dosage of Levomac 500 MG Infusion 100 ML

Daily Dose

The daily dose of Levomac I.V. Infusion should be administered as advised by your doctor. The dosage might differ based on factors such as the severity of your condition and your response to the medication. Always adhere to the dosage prescribed by your doctor without exceeding it. For further details, refer to the package insert.

Over Dose

If you suspect an overdose of Levomac I.V. Infusion, you might experience symptoms like drowsiness or feelings of nausea. In such a scenario, it's vital to inform your doctor to manage these symptoms effectively.

Missed Dose

If you forget to administer your regular dose of Levomac I.V. Infusion, do so as soon as you remember. However, if it's nearly time for the next dose, skip the missed one and continue with your normal schedule. It's crucial not to increase your dosage without consulting your doctor.

Keep Levomac I.V. Infusion at controlled room temperature, not exceeding 30°C.
Protect the medicine from light and avoid extreme heat.
Do not freeze Levomac I.V. Infusion.
Keep it out of the reach of children.

If you're using Levomac I.V. Infusion to manage pneumonia, ensure to consume a balanced diet rich in fruits, vegetables, lean proteins, and whole grains to boost your immune system.
For urinary tract infections (UTIs), keep yourself hydrated. Drink plenty of fluids, especially water, which can help flush bacteria out of your system.

Fact Box

Drug Category	DNA Synthesis Inhibitor
Therapeutic Category	Antibiotic
Available Dosage Types	IV Infusion
Habit Forming	No
Ailment	Pneumonia, Urinary Tract Infections, Sinusitis

What is Levomac I.V. Infusion used for?

Levomac I.V. Infusion is used to manage various bacterial infections including pneumonia, urinary tract infections, sinusitis, prostatitis, skin infections, and plague.

How does Levomac I.V. Infusion work?

Levomac I.V. Infusion's active ingredient, levofloxacin, stops bacteria from growing by inhibiting their essential DNA functions, leading to bacterial cell death.

Can Levomac I.V. Infusion be given to patients with kidney problems?

Yes, but dosage adjustments are necessary. The medicine should be administered carefully in patients with kidney impairment.

Are there any side effects of Levomac I.V. Infusion?

Common side effects include nausea, diarrhoea, headache, insomnia, dizziness and reactions at the injection site. Consult your doctor if these persist or worsen.

Can Levomac I.V. Infusion causes harm during pregnancy?

Levomac I.V. Infusion may cause harm to the foetus and should only be used in pregnancy if the benefits outweigh the risks. Always consult your doctor.

Can nursing mothers use Levomac I.V. Infusion?

Levomac I.V. Infusion enters breast milk and may harm nursing infants. It's therefore advisable to consult your doctor before using this medicine while breastfeeding.

What should I do in case of a Levomac I.V. Infusion overdose?

In case of an overdose on Levomac I.V. Infusion causing symptoms like drowsiness and convulsions, seek immediate medical help. The treatment usually involves discontinuing the medication and supportive care.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 9 years

Doctor of Medicine

Reviewed by

Dr. Saniya K Mulla

Medical Writer & Reviewer | 6 years

MBBS

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Manufacturer details

Atlanta Arcade, Marol Church Rd, Bori Colony, Vijay Nagar Colony West, Marol, Andheri East, Mumbai, Maharashtra 400059

Country of origin: INDIA

References

Levofloxacin: uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01137
Levofloxacin: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a697040.html
DailyMed - LEVOFLOXACIN injection. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4438fed2-7ef5-488f-baa8-39bc65768d1d
D-glucose: uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01914
National Center for Biotechnology Information (2024). PubChem Compound Summary for , Anhydrous Dextrose. Retrieved June 20, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Anhydrous-Dextrose

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