Lipi Ez 4010 Mg Tablet 10

Lipi Ez 40 Tablet 10

Intas Pharmaceuticals Ltd

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Composition

Atorvastatin (40 Mg) + Ezetimibe (10 Mg)

Lipi EZ 40 Tablet is primarily used to manage high cholesterol levels in the body. This combination medicine forms part of a group of medicines known as statins and cholesterol absorption inhibitors.

Aside from this main use, this medicine also reduces the quantity of harmful fatty substances such as low-density lipoprotein (LDL) or "bad" cholesterol and triglycerides in the blood. By doing so, it helps increase the level of high-density lipoprotein (HDL) or "good" cholesterol.

This medicine should be taken orally as guided by your doctor. It's crucial to tell your doctor about any existing health conditions or ongoing medicines before starting this medicine. If you notice any unusual effects while taking this medicine, immediately inform your doctor. Ensure you continue the medicine for the duration recommended by your doctor to achieve the best results.

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Lipi EZ 40 Tablet has the following uses:

Reducing high cholesterol levels: This medicine helps to lower the amount of cholesterol in your blood.
Managing hypercholesterolemia: If your cholesterol level is too high, this medicine can help to manage it effectively.
Decreasing risk of heart disease: By lowering your cholesterol, Lipi EZ 40 Tablet reduces the risk of developing heart disease.
Preventing heart attacks and strokes: Regular use can help guard against these serious health events.
Reducing triglycerides: Lipi EZ 40 Tablet can lower the amount of fats in your blood.

Directions for Use of Lipi Ez 40 Tablet 10

Here's how you should take Lipi EZ 40 Tablet:

Swallow the tablet whole with a glass of water.
Avoid crushing or chewing the tablet as it might reduce its effectiveness.
Follow your doctor's advice carefully. Don't stop taking this medicine without consulting your doctor, even if you feel well.
If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, just skip the missed one and stick to your regular schedule. Don’t take two doses at the same time.

Lipi EZ 40 Tablet is taken orally.

Lipi EZ 40 Tablet may have the following common side effects:

Headache
Diarrhoea
Muscle or joint pain
Nausea
Fatigue
Rhabdomyolysis: This is a rare side effect that involves muscle damage. It can cause unexplained muscle pain, tenderness, or weakness.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolves on discontinuing the use of Lipi EZ 40 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some general guidelines for managing common side effects:

Diarrhoea: Try taking Lipi EZ 40 Tablet with food or milk.
Nausea: Consider taking this medicine after meals to lessen this effect.

Lipi EZ 40 Tablet contains two active ingredients:

Atorvastatin (40 mg): As an HMG-CoA reductase inhibitor, atorvastatin works in your liver to reduce cholesterol production. It acts by blocking an enzyme called HMG-CoA reductase, which is required to make cholesterol. Additionally, it increases the number of LDL receptors on liver cells, which helps to take up and break down more LDL cholesterol.
Ezetimibe (10 mg): This ingredient works by reducing cholesterol absorption in the intestines. It does this by localising at the brush border of your intestinal cells, preventing cholesterol from being absorbed into your bloodstream. This results in less cholesterol being delivered to the liver.

Pregnancy

Lipi EZ 40 Tablet is contraindicated during pregnancy. If you're pregnant or planning to conceive, discuss this with your doctor before starting this medicine.

Breastfeeding

Lipi EZ 40 Tablet is contraindicated for breastfeeding women. Consult your doctor to understand potential risks and benefits.

Alcohol

It's advised to limit alcohol consumption while taking Lipi EZ 40 Tablet. Excessive alcohol may increase the risk of liver problems. Always consult your doctor for guidance.

Liver

Caution is advised while taking Lipi EZ 40 Tablet in case of mild to moderate liver impairment. It's not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting this medication.

Kidney

Caution is advised before using Lipi EZ 40 Tablet if you have a history of kidney problems. It's a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

No specific precautions are required while using machines or driving after taking Lipi EZ 40 Tablet. However, if you feel dizzy or unwell after taking the medicine, avoid such activities and consult your doctor.

Allergy

If you're allergic to atorvastatin, ezetimibe, or any component of Lipi EZ 40 Tablet, do not take this medicine without discussing with your doctor.

Children

Lipi EZ 40 Tablet should not be given to children under 18 years of age without medical supervision. Always consult your doctor first.

Older Patients

Older patients should take Lipi EZ 40 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised for patients above 70 years of age due to potential liver and kidney issues. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Lipi EZ 40 Tablet interacts with the following medicines:

Antibiotics: Lipi EZ 40 Tablet may interact with antibiotics like erythromycin and clarithromycin, which could increase the risk of muscle damage.
Antifungal Medications: Taking antifungals such as itraconazole with this medicine might elevate the levels of atorvastatin in your blood, potentially increasing the likelihood of side effects.
Immunosuppressants: If you're on medicines like cyclosporine that suppress the immune system, they may interact with Lipi EZ 40 Tablet, causing elevated statin levels and an increased risk of adverse effects.
HIV Protease Inhibitors: These HIV medications like Amprenavir and Atazanavir can interact with Lipi EZ 40 Tablet, leading to higher statin levels and potential side effects.
Cholesterol-lowering Agents: Fibrates like gemfibrozil and fenofibrate, another type of cholesterol-lowering medication, may interact with Lipi EZ 40 Tablet, potentially increasing the risk of muscle damage.

Drug-Food Interactions

The following food items can interact with Lipi EZ 40 Tablet:

Grapefruit and Grapefruit Juice: These can increase the level of statins in your blood if consumed whilst taking Lipi EZ 40 Tablet, thereby raising the risk of side effects.

Drug-Disease Interactions

Lipi EZ 40 Tablet interacts with the following diseases:

Liver Disease: If you have liver disease, taking Lipi EZ 40 Tablet could exacerbate your condition. This is due to atorvastatin's metabolism in the liver.
Kidney Disease: Patients with kidney disease need to be cautious as this medicine might lead to increased medicinal levels in their body.
Diabetes: For diabetic patients, Lipi EZ 40 Tablet could potentially impact blood sugar control. It’s essential then for glucose levels to be monitored closely when on this medication.

Daily Dose

The daily dose of Lipi EZ 40 Tablet should be taken as directed by your doctor. Your dosage can vary depending on factors like the severity of your condition and how you respond to the medication. It's crucial to follow your doctor's instructions and not exceed the prescribed dosage without consulting your doctor.

Over Dose

If you inadvertently take more Lipi EZ 40 Tablet than recommended, you may experience common side effects like headache, diarrhoea, and muscle or joint pain. If these symptoms persist or worsen, inform your doctor.

Missed Dose

If you forget to take your Lipi EZ 40 Tablet, take it as soon as you recall. If it's close to time for the next dose, skip the missed one and continue with your regular schedule. Always consult your doctor before making any changes to your dosage.

Store Lipi EZ 40 Tablet at a stable room temperature of 20-25°C.
Keep the medicine in a secure, tightly closed container, away from excessive light and moisture.
Ensure to store this medication out of reach of children to prevent accidental ingestion.
Use the tablets before the expiry date mentioned on the package.

Follow a heart-healthy diet that is rich in fibre and low in saturated fats. This helps manage high cholesterol levels, which the Lipi EZ 40 Tablet is designed to control.
Regular physical activity is also crucial. Aim for at least 30 minutes of moderate exercise daily, like brisk walking or cycling. This supports cardiovascular health and aids in controlling your cholesterol levels.

Fact Box

Drug Category	HMG CoA Reductase Inhibitor, Cholesterol Absorption Inhibitor
Therapeutic Category	Lipid-lowering Agent
Available Dosage Types	Tablet
Habit Forming	No
Ailment	High Cholesterol, Hypertriglyceridemia

What is Lipi EZ 40 Tablet used for?

Lipi EZ 40 Tablet is used to manage high cholesterol levels when diet and lifestyle changes alone have not been sufficient.

How does Lipi EZ 40 Tablet work?

The medicine contains atorvastatin and ezetimibe which reduce cholesterol production in the liver and absorption in the intestines, respectively.

How should Lipi EZ 40 Tablet be taken?

Lipi EZ 40 Tablet should be taken orally, as directed by your doctor, usually once daily with or without food.

What are the potential side effects of Lipi EZ 40 Tablet?

Common side effects may include headache, diarrhoea, muscle or joint pain, nausea and fatigue. Always consult your doctor if these occur.

What precautions should I take before using Lipi EZ 40 Tablet?

Inform your doctor about any allergies, existing health conditions like liver or kidney disease, diabetes, thyroid problems, alcohol use, and any recent surgeries.

Can I take other medications with Lipi EZ 40 Tablet?

Certain medicines may interact with Lipi EZ 40 Tablet. Always inform your doctor about all current medications to avoid harmful interactions.

What should I do if I miss a dose of Lipi EZ 40 Tablet?

If a dose is missed, take it as soon as you remember. If it's nearly time for the next dose, skip the missed one and resume your schedule.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Corporate House, Near Sola Bridge, S. G. Highway, Thaltej, Ahmedabad 380054, Gujarat, India

Country of origin: INDIA

References

U.S. National Library of Medicine. (2021). Atorvastatin. MedlinePlus. Retrieved on 1 April 2024 from https://medlineplus.gov/druginfo/meds/a600045.html
U.S. National Library of Medicine. (2021). Ezetimibe. MedlinePlus. Retrieved on 1 April 2024 from https://medlineplus.gov/druginfo/meds/a603015.html
U.S. Food and Drug Administration. (2009). FDA Label - Atorvastatin. Accessdata.fda.gov. Retrieved on 1 April 2024 from https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020702s057lbl.pdf
U.S. Food and Drug Administration. (2006). FDA Label - Ezetimibe. Accessdata.fda.gov. Retrieved on 1 April 2024 from https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021445s014lbl.pdf
Atorvastatin. (n.d.). Retrieved 22 October 2024, from https://go.drugbank.com/drugs/DB01076
Ezetimibe. (n.d.). Retrieved 22 October 2024, from https://go.drugbank.com/drugs/DB00973

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