Lupibend 400 Mg Tablet 1

Lupibend 400 Tablet 1

Lupin Ltd

Strip of 1 Units

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Composition

Albendazole (400 Mg)

Lupibend 400 Tablet 1 is primarily used to manage parasitic worm infections. It is part of a group of medications known as anthelmintics.

This medicine is used in the management of specific tapeworm infections. It helps manage neurocysticercosis (a condition caused by the larval form of the pork tapeworm, Taenia solium) and hydatid disease (a condition triggered by the larval form of the dog tapeworm, Echinococcus granulosus).

Before you start taking this medicine, it's important to consult your doctor about your medical history and any ongoing medications. If you experience any side effects while on this medicine, consult your doctor immediately. Continue taking the medicine for the duration prescribed by your doctor for optimal results.

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Lupibend 400 Tablet 1 is used for managing the following medical conditions:

Specific tapeworm infections
Neurocysticercosis, a form of parasitic infection caused by larval forms of the pork tapeworm, T. solium
Hydatid disease, a condition involving cyst formation in the liver, lung, and peritoneum, caused by the larval form of the dog tapeworm, E. granulosus

Directions for Use of Lupibend 400 Tablet 1

Swallow the tablet whole with a glass of water.
If you have difficulty swallowing it whole, you can crush or chew the tablet before swallowing it with water.
Always take the medicine in the dosage and frequency prescribed by your doctor.
Continue taking this medicine for the full duration prescribed by your doctor, even if you start to feel better.

Lupibend 400 Tablet 1 is taken orally.

Lupibend 400 Tablet 1 may have the following common side effects:

Nausea or vomiting
Abdominal pain
Headache
Dizziness
Loss of appetite

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the medicine. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

You can also effectively manage common side effects like nausea, vomiting, or abdominal pain at home by taking the medicine with food or after your meals.

Lupibend 400 Tablet 1 contains albendazole (400 mg) as the active ingredient. It works in the human body in the following manner:

Albendazole works by blocking a process called tubulin polymerisation in the larval forms of certain parasites. This process is crucial for the formation of cytoplasmic microtubules, which are small structures inside parasites' cells.
By inhibiting tubulin polymerisation, albendazole impairs glucose uptake in these parasites, depleting their energy stores. Thus, it is difficult for the parasites to survive and grow.

Pregnancy

Lupibend 400 Tablet 1 is contraindicated in pregnancy as it could potentially harm the foetus. If you are pregnant or planning to conceive, consult your doctor before starting this medicine.

Breastfeeding

If you are breastfeeding, it is advised to exercise caution as albendazole may pass into breast milk and adversely affect your baby. Always consult your doctor before taking this medicine.

Alcohol

Avoid alcohol consumption while on this medication as it may increase the risk of side effects such as dizziness. Always consult your doctor regarding alcohol intake.

Liver

Lupibend 400 Tablet 1 should be used cautiously if you have liver problems. It can affect liver function, especially in those with pre-existing liver conditions. Regular monitoring of liver functions might be required while taking this medicine. Always consult your doctor before starting this medication.

Kidney

If you have kidney problems, caution is advised while taking this medicine. Always discuss your kidney health concerns with your doctor before using this medication.

Using Machines & Driving

This medicine may cause dizziness as a side effect. If you feel dizzy or unwell after taking this tablet, avoid driving or operating heavy machines until you feel better.

Allergy

Avoid taking this medicine if you are allergic to albendazole or any of the tablet's ingredients. Always discuss your allergies with your doctor.

Children

This medicine should not be given to children under 18 years without medical advice. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should use this medicine under medical supervision due to increased susceptibility to its side effects. It's important to consult a doctor, particularly if you have liver or kidney issues or are on other medications.

Drug-Drug Interactions

Lupibend 400 Tablet 1 may interact with the following medications:

Corticosteroids: Medicines like dexamethasone can increase the levels of albendazole in your body, potentially intensifying its side effects.
Heartburn and ulcer medications: Medications like cimetidine can increase the concentration of albendazole in your body, causing adverse effects.
Other antiparasitic agents: Medicines such as praziquantel, used for managing parasitic worm infections, may interact with Lupibend 400 Tablet 1 and enhance its effects, leading to unwanted side effects.

Drug-Food Interactions

Lupibend 400 Tablet 1 may interact with certain foods, such as:

Grapefruit juice: Consuming grapefruit or its juice while taking this medicine could increase the absorption of albendazole, causing adverse side effects.

Drug-Disease Interactions

Lupibend 400 Tablet 1 may interact with the following diseases:

Liver disease: If you have liver disease, Lupibend 400 Tablet 1 should be used cautiously as it could worsen your condition.
Blood disorders: People with blood disorders should take caution as this medicine could cause bone marrow suppression, resulting in lower blood cell counts.
Neurologic dysfunction: Patients with conditions such as seizures or epilepsy should exercise caution while on this medication as it may trigger or intensify seizure episodes.

Daily Dose

The dose of Lupibend 400 Tablet 1 should be taken as prescribed by your doctor. The dosage may vary according to the severity of your condition and your response to the medicine.

Over Dose

If you accidentally take more than the prescribed dose, you might experience symptoms like nausea, vomiting, or abdominal pain. If you experience such symptoms or feel unwell, consult your doctor promptly.

Missed Dose

If you forget to take the medicine at the scheduled time, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed one and continue with your regular schedule. Don't increase your dose without consulting your doctor.

Store Lupibend 400 Tablet 1 at room temperature, ideally below 25°C.
Protect it from light and moisture to maintain its efficacy.
Always keep this medicine out of reach of children.
Ensure you use the tablet before the expiry date mentioned on the product packaging.

If you have neurocysticercosis, consider eating a diet high in protein. This will support your body's recovery as it fights off the tapeworm infection.
Personal hygiene is crucial; always wash your hands thoroughly after handling pets or outdoor activities.

Fact Box

Drug Category	Tubulin Polymerisation Inhibitor
Therapeutic Category	Anthelmintic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Neurocysticercosis, Hydatid Disease

What is Lupibend 400 Tablet 1 used for?

Lupibend 400 Tablet 1 is used to manage specific tapeworm infections, including neurocysticercosis and hydatid disease.

How does Lupibend 400 Tablet 1 work?

This medicine contains albendazole, a compound that disrupts the worms' energy supply and eventually causes their death. It specifically targets the worms' ability to absorb glucose.

How should I take Lupibend 400 Tablet 1?

Always take this medicine in the dosage and frequency prescribed by your doctor. It is usually taken with meals, at the same time each day, for maximum effectiveness.

Can I take Lupibend 400 Tablet 1 during pregnancy?

No, it's contraindicated during pregnancy as it may cause potential harm to the foetus. Always consult your doctor before starting this medicine.

Is it safe to consume grapefruit juice while taking Lupibend 400 Tablet 1?

Avoid grapefruit and its juice while on this medication as it can increase the risk of unwanted side effects.

What are the potential side effects of Lupibend 400 Tablet 1?

The medicine's common side effects include abdominal pain, nausea, dizziness, and headache. If these symptoms persist or worsen, inform your doctor.

How should I store Lupibend 400 Tablet 1?

Store the medicine at room temperature away from light and moisture. Keep out of reach of children and discard any unused medication safely.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Kalpataru Inspire, 3rd Floor, Off. Western Express Highway, Santacruz (East), Mumbai

Country of origin: INDIA

References

NDA 20-666/S-005 & NDA 20-666/S-006. (n.d.). PRESCRIBING INFORMATION ALBENZA (albendazole) Tablets(pp. 4–6). https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020666s005s006lbl.pdf
Malik, K., & Dua, A. (2023, April 10). Albendazole. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK553082/
Albendazole: MedlinePlus Drug Information. (n.d.). https://medlineplus.gov/druginfo/meds/a610019.html
Albendazole: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00518
Albendazole. (n.d.). sciencedirect.com. https://www.sciencedirect.com/topics/medicine-and-dentistry/albendazole

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