Mabura 40 MG Injection 1 ML

Hetero Healthcare Ltd

Pack of 1 ML

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MRP ~~₹25000~~

₹20000

₹25000/ML

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Store in refrigerator or (2^o - 8^o C) Do Not Freeze

Composition

Adalimumab (40 Mg)

Mabura 40 MG Injection is primarily used to manage various autoimmune disorders. It's part of a group of medications known as tumour necrosis factor (TNF) blockers.

This medicine is also used for the management of conditions like rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, plaque psoriasis, uveitis, and juvenile idiopathic arthritis (in children 2 years and older). It's particularly effective in reducing joint pain, stiffness, and swelling, as well as slowing joint damage in inflammatory arthritis.

Before starting this medication, you should consult your doctor to decide on the proper dosage and frequency. Let your doctor know about any pre-existing conditions or ongoing medications you're currently on. If you notice any side effects while on this medicine, notify your doctor immediately. It's important to continue taking the medicine for the duration prescribed by your doctor for optimal results.

Mabura 40 MG Injection is used for the following:

Management of rheumatoid arthritis.
Control of psoriatic arthritis.
Reduction of ankylosing spondylitis symptoms.
Management of Crohn's disease.
Control of ulcerative colitis.
Alleviation of plaque psoriasis symptoms.
Management of hidradenitis suppurativa.
Control of non-infectious uveitis.
Management of juvenile idiopathic arthritis (in children 2 years and older).

Directions for Use of Mabura 40 MG Injection 1 ML

Administer Mabura 40 MG Injection as follows:

This medicine will be administered as a subcutaneous injection by a healthcare professional, usually under your skin.
Rotate the sites for each injection. You could choose from your thigh, abdomen, or upper arm.
For specific instructions regarding dosage and frequency, consult your doctor.

Mabura 40 MG Injection is administered subcutaneously.

Side Effects of Mabura 40 MG Injection 1 ML

Mabura 40 MG Injection may have the following common side effects:

Injection site reactions: These can consist of redness, rash, swelling, itching, bruising, or pain at the spot where you administer the injection.
Upper respiratory infections: This could mean a sinus infection, which usually involves the nasal passages and sinuses becoming inflamed.
Mood alteration
Vision disorders
A sensation of dizziness or spinning

Managing the Side Effects:

Most side effects are temporary and generally harmless, which are resolved by discontinuing the use of Mabura 40 MG Injection. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Below are some general guidelines for managing common side effects:

Injection site reactions: Rotating the injection sites (thigh, abdomen, upper arm) might help to minimise these reactions.
Mood alteration: Practice mindfulness meditation or deep breathing exercises to reduce stress and improve your overall well-being.

Mabura 40 MG Injection contains adalimumab (40 MG) which works on your body in the following ways:

Binds to TNF-alpha: Adalimumab binds to a protein in your body called TNF-alpha. This protein is a major player in causing inflammation in your body.
Reduces inflammation: By binding to TNF-alpha, adalimumab inhibits its activity. This effectively reduces inflammation, pain, and other symptoms associated with autoimmune disorders.

Pregnancy

Mabura 40 MG Injection should only be used during pregnancy if necessary. If you are pregnant or planning to conceive, it's best to discuss this with your doctor before starting this medicine.

Breastfeeding

If you are breastfeeding, the use of Mabura 40 MG Injection should be decided upon after a careful discussion with your doctor, considering the potential risks and benefits.

Alcohol

There is no specific information available about interactions between Mabura 40 MG Injection and alcohol. However, it is always wise to consult your doctor.

Liver

Caution is advised while taking Mabura 40 MG Injection if you have any liver health issues. Please consult your doctor before starting this medicine.

Kidney

As Mabura 40 MG Injection may cause side effects that could affect your ability to drive or operate machinery, caution is advised. Discuss any concerns with your doctor.

Using Machines & Driving

As Mabura 40 MG Injection may cause side effects like vertigo and vision disorders that could affect your ability to drive or operate machinery, caution is advised. Discuss any concerns with your doctor.

Allergy

Mabura 40 MG Injection should not be used if you have known hypersensitivity to adalimumab or any of its inactive ingredients.

Children

While Mabura 40 MG Injection can be used in children older than 2 years for certain conditions, caution is advised. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Mabura 40 MG Injection under medical supervision, as they might be more prone to its side effects. Your doctor will guide you based on your health status.

Interactions of Mabura 40 MG Injection 1 ML

Drug-Drug Interactions

Mabura 40 MG Injection interacts with the following medicines:

Anti-cancer medications Medicines such as methotrexate may interact with Mabura 40 MG Injection, possibly reduce the effect of adalimumab.
Immune system medications: Medications like abatacept and anakinra may interact with Mabura 40 MG Injection, potentially leading to altered medication effects or an increased risk of side effects.

Drug-Food Interactions

Mabura 40 MG Injection has no known interactions with food items.

Drug-Disease Interactions

Mabura 40 MG Injection interacts with the following diseases:

Active Infections: Patients with active infections, including localised infections, should be cautious as Mabura 40 MG Injection could exacerbate their condition.
Tuberculosis: Before starting Mabura 40 MG Injection, patients should be evaluated for tuberculosis risk factors and tested for latent infection.
Hepatitis B: There is a risk of reactivation of hepatitis B in patients who carry this virus in their blood.
Heart Failure: Patients with heart failure or those at risk should be closely monitored while on Mabura 40 MG Injection as it could worsen their condition.
Liver Disease: Patients with liver disease should exercise caution as the use of Mabura 40 MG Injection could exacerbate their condition.

Daily Dose

The daily dose of Mabura 40 MG Injection will be administered by your doctor or healthcare professional. The dosage can vary based on your individual health profile, including the severity of your condition and how you respond to the medication. Always adhere to your prescribed dose and avoid exceeding it without consulting your doctor.

Over Dose

If you happen to administer more than the recommended dose of Mabura 40 MG Injection, you may experience certain side effects. If these symptoms persist or worsen, inform your doctor.

Missed Dose

If you forget to administer your scheduled dose of Mabura 40 MG Injection, do so as soon as you remember. However, if it's nearly time for your next dose, skip the one you missed and continue with your regular schedule. Don't increase your dosage without consulting your doctor.

Keep Mabura 40 MG Injection in the fridge, ideally between 2°C and 8°C.
Do not freeze the injection or expose it to extreme heat or sunlight.
If needed, you can store it at room temperature (up to 25°C) for up to 14 days. Discard if not used after this period.
Keep the medicine out of the reach of children.
Always check the expiration date before use.

If you're managing rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis with Mabura 40 MG Injection, try to maintain a balanced diet rich in Omega-3 fatty acids (found in fish and chia seeds), which can help reduce inflammation.
If you have Crohn's disease or ulcerative colitis, opt for a diet with plenty of fibre from sources like fruits, vegetables, and whole grains to support digestion. However, during flare-ups, a low-residue diet might be more suitable. Always consult your doctor for personalized advice.

Fact Box

Drug Category	TNF Blocker
Therapeutic Category	Anti-inflammatory
Available Dosage Types	Injection
Habit Forming	No
Ailment	Rheumatoid arthritis, Psoriatic arthritis

How long does it take for Mabura 40 MG Injection to work?

The effects of Mabura 40 MG Injection can start to show within 2-12 weeks, but it may take up to 3-6 months for full benefits.

Can I have live vaccines while taking Mabura 40 MG Injection?

No, live vaccines should be avoided while you are on Mabura 40 MG Injection and for at least five months after the last dose.

What if I miss a dose of Mabura 40 MG Injection?

If you miss a dose of Mabura 40 MG Injection, aminister the missed dose as soon as you remember. Resume your next dose at your regular scheduled time.

Can I stop taking Mabura 40 MG Injection if my symptoms improve?

You should not stop taking Mabura 40 MG Injection without consulting your doctor as your symptoms might return.

How should I dispose of used Mabura 40 MG Injection syringes or pens?

Dispose used syringes and pens of Mabura 40 MG Injection following local disposal guidelines.

Will Mabura 40 MG Injection interact with other medications?

Yes, Mabura 40 MG Injection can interact with other medications, particularly with other TNF blockers and medications that affect the immune system. Always inform your doctor about other medications you're taking.

Is it safe to use Mabura 40 MG Injection during pregnancy?

Inform your doctor if you're pregnant or plan to be. Use of Mabura during pregnancy should only occur if clearly needed.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 3 years

Bachelor of Dental Surgery

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Manufacturer details

A-201/202/B-201, Dipti Classic, 32/34, W.T. Suren Rd, Andheri East, Mumbai, Maharashtra 400093

Country of origin: INDIA

References

MedlinePlus. (n.d.). Adalimumab Injection. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a603010.html
U.S. Food and Drug Administration. (2023). Highlights of prescribing information: Humira (adalimumab). Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/761154Orig1s008lbl.pdf
National Center for Biotechnology Information (2024). PubChem Compound Summary for , Adalimumab. Retrieved November 26, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Adalimumab
Ellis, C. R., & Azmat, C. E. (2023). Adalimumab. In StatPearls. StatPearls Publishing. https://pubmed.ncbi.nlm.nih.gov/32491812/
Scheinfeld N. (2005). Adalimumab: a review of side effects. Expert opinion on drug safety, 4(4), 637–641. https://doi.org/10.1517/14740338.4.4.637

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