Macfloxmacleods 400 Mg Tablet 10

Macflox Tablet 10

Macleods Pharmaceuticals Pvt.ltd

Strip of 10 Units

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Composition

Moxifloxacin (400 Mg)

Macflox Tablet is primarily used to manage various types of bacterial infections. This medication is categorised as a broad-spectrum antibiotic, which is part of the fourth-generation fluoroquinolones.

The tablet is effective in managing respiratory tract infections, skin and soft tissue infections, and intra-abdominal infections. It's especially useful for conditions such as acute bacterial sinusitis, acute bacterial exacerbation of chronic bronchitis, community-acquired pneumonia, uncomplicated skin structure infections, and complicated intra-abdominal infections.

Before starting this medication, consult your doctor regarding the appropriate dosage and frequency. It's crucial to inform your doctor about any pre-existing conditions or ongoing medications. If you observe any side effects while taking this medicine, notify your doctor immediately. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

Macflox Tablet is used for managing the following health conditions:

Acute bacterial sinusitis (a short-term infection of the sinuses)
Acute bacterial exacerbation of chronic bronchitis (sudden worsening of long-standing bronchitis due to a bacterial invasion)
Community-acquired pneumonia (a lung infection picked up in a community setting)
Uncomplicated (simple) skin and skin structure infections
Complicated (complex) intra-abdominal infections

Here's how you should take Macflox Tablet:

Swallow the tablet whole with a glass of water.
Do not crush, chew, or split the tablet.
Take it with or without food, as per your comfort.
Always follow your doctor's advice on how much and how often to take this medicine.

Macflox Tablet is taken orally.

While taking Macflox Tablet, you may experience some common side effects. These include:

Nausea
Diarrhoea
Dizziness
Headache
Abdominal Pain
Vomiting

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Macflox Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

You can try taking Macflox Tablet with food to reduce feelings of nausea and vomiting.

Macflox Tablet contains moxifloxacin (400 mg), which operates in your body through the following mechanisms:

Inhibition of DNA Enzymes: Moxifloxacin works by blocking two enzymes: bacterial DNA gyrase and topoisomerase IV. These enzymes are essential for the replication, transcription, repair, and recombination processes of bacterial DNA.
Control of Bacterial Growth: By inhibiting these key enzymes, moxifloxacin successfully prevents the bacteria from multiplying and spreading. This action results in controlling the bacterial infection and eventually leading to their death.

Pregnancy

Caution is advised when taking Macflox Tablet during pregnancy. It is wise to consult your doctor before using this medicine.

Breastfeeding

While breastfeeding, it's recommended to use Macflox Tablet with caution. Consulting your doctor is advisable to understand the potential risks and benefits.

Alcohol

You're advised to avoid alcohol while taking Macflox Tablet as it may increase certain side effects like dizziness and drowsiness.

Liver

If you have mild to moderate liver impairment, it's important to be careful while taking Macflox Tablet. This medicine may affect liver function, so discuss this with your doctor before starting use.

Kidney

Use of Macflox Tablet should be undertaken with caution if you have any history of kidney issues. Consultation with your doctor prior to taking this medicine is recommended.

Using Machines & Driving

Macflox Tablet may cause dizziness or confusion. These side effects could influence your ability to operate machinery or drive safely. Be cautious until you know how this medicine affects you.

Allergy

If you have a known hypersensitivity to moxifloxacin or any other components of Macflox Tablet, its usage is contraindicated.

Children

Macflox Tablet should not be given to children or adolescents under 18 years of age. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should use Macflox Tablet under medical supervision as they could be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Macflox Tablet interacts with the following medicines:

Antacids and mineral supplements: These can lower the effectiveness of Macflox Tablet, as they may reduce the absorption of moxifloxacin. Examples include aluminium or magnesium-containing antacids, sucralfate, and iron or zinc supplements.
Blood thinners: Medicines like warfarin may interact with Macflox Tablet, increasing your risk of bleeding.
Antidiabetic agents: Moxifloxacin can interfere with blood sugar control. When taken with antidiabetic mediciations such as metformin or glimepiride, you might experience changes in your blood sugar levels.
Nonsteroidal anti-inflammatory drugs (NSAIDs): Taking NSAIDs such as ibuprofen or naproxen with this tablet can increase the risk of central nervous system stimulation and seizures.
Diuretics: Diuretics such as furosemide and
hydrochlorothiazide may increase the risk of torsade de pointes (a type of abnormal heart rhythm)
when given with moxifloxacin.

Drug-Food Interactions

Certain foods can interact with Macflox Tablet.

Dairy Products: Foods rich in calcium, such as milk and cheese, may decrease moxifloxacin absorption.

Drug-Disease Interactions

Macflox Tablet interacts with the following diseases:

Myasthenia gravis: People with this muscle weakness disorder should be cautious when taking Macflox Tablet, as it may worsen their symptoms.
Heart conditions: If you have a history of QT prolongation or an imbalance in your body's electrolytes, use this medicine carefully. It can affect your heart rhythm, leading to a potentially serious condition called torsades de pointes.
Hypokalaemia: If you have low amounts of potassium in your blood, moxifloxacin may increase your risk of getting torsade de pointes or having a fast, slow, or irregular heartbeat.

Daily Dose

Your doctor will prescribe the appropriate daily dosage of Macflox Tablet for you based on your individual circumstances, such as the severity of your condition and how well you respond to the medication. It's crucial to follow your doctor's instructions carefully and not exceed the prescribed dosage without their advice.

Over Dose

If you accidentally take an excess of Macflox Tablet, it may result in common overdose symptoms such as dizziness, confusion, vomiting, diarrhoea, and tremors. If you experience these symptoms, seek medical advice from your doctor.

Missed Dose

If you forget to take a dose of Macflox Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, don't worry about the missed one and just carry on with your normal schedule. Remember not to double up on doses without consulting your doctor.

Store Macflox Tablet in a cool and dry place, ideally at room temperature between 15-30°C.
Protect the medicine from light and moisture.
Keep the tablet out of reach and sight of children.
Always check the expiry date on the package before taking the tablet.

If you're taking Macflox Tablet for respiratory infections, avoid smoking and being around second-hand smoke as it can worsen your condition.
For those using Macflox Tablet for skin or soft tissue infections, maintain good hygiene and keep your skin clean to prevent further infection.

Fact Box

Drug Category	DNA Gyrase Inhibitor
Therapeutic Category	Antibiotic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Acute Sinusitis, Pneumonia, Skin Infections

What does Macflox Tablet do?

Macflox Tablet is a broad-spectrum antibiotic, used to manage a variety of bacterial infections by inhibiting essential enzymes in bacteria.

Can I eat before taking Macflox Tablet?

Yes, this medicine can be taken with or without food. Always follow the specific instructions given by your doctor.

How long does it take for Macflox Tablet to work?

While you may feel better within a few days, ensure you complete the prescribed course even if symptoms improve earlier.

Can I consume alcohol while taking Macflox Tablet?

Avoid alcohol while on this medicine, as it may increase side effects like dizziness and drowsiness.

What happens if I miss a dose of Macflox Tablet?

Take the missed dose as soon as you remember. If it's nearly time for your next one, skip the missed dose and continue your usual schedule.

Is it safe to use Macflox Tablet during pregnancy or breastfeeding?

The tablet is not recommended for use during pregnancy or nursing. Always consult your doctor before usage during these periods.

What should I do in case of an overdose?

In case of an overdose, seek immediate medical attention. Symptoms may include dizziness, confusion, and occasionally seizures.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Snigdha Sharma

Clinical Health & Medical Reviewer | 6 years

MBBS

Check out Editorial Policy

Manufacturer details

Atlanta Arcade, Marol Church Rd, Bori Colony, Vijay Nagar Colony West, Marol, Andheri East, Mumbai, Maharashtra 400059

Country of origin: INDIA

References

IBM Watson Health. (2021). Moxifloxacin. In IBM Micromedex® DRUGDEX® (electronic version). Greenwood Village, Colorado, USA. Available at: https://www.micromedexsolutions.com/ (Accessed: 29 April 2024).
Avelox 400 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (EMC). (n.d.). https://www.medicines.org.uk/emc/product/6771/smpc
MedlinePlus. (n.d.). Moxifloxacin. Available at: https://medlineplus.gov/druginfo/meds/a600002.html (Accessed: 29 April 2024).

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