Melanocyl 0752 Ointment 25 Gm

Melanocyl Ointment 25gm

Franco Indian Pharmaceuticals Pvt Ltd

Tube of 25 GM

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MRP ~~₹125.28~~

₹102.73

₹5.01/GM

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Composition

Aminobenzoic Acid (2 %) + Methoxsalen (0.75 %)

Melanocyl Ointment is primarily used to manage vitiligo, a chronic skin condition where the loss of pigmentation results in white patches. This medication is a combination product that belongs to the class of medicines known as psoralens.

In addition to managing vitiligo, this is used to restore skin colour in the affected areas. The method involves repigmentation of hypopigmented lesions, which are light or white patches on the skin.

Before beginning this medication, it's crucial to consult with your doctor about the dosage and frequency. Make sure to inform your doctor about any ongoing medications or pre-existing conditions you have. If you notice any side effects while using this medicine, notify your doctor right away. It's important to continue using it for the duration prescribed by your doctor in order to see optimal results.

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Melanocyl Ointment is used for managing the following conditions:

Restoring skin colour in skin areas affected by vitiligo
Repigmentation of hypopigmented lesions linked to vitiligo
Stimulation of melanocytes, the pigment-producing cells, in the skin

Directions for Use of Melanocyl Ointment 25gm

Using Melanocyl Ointment is quite straightforward. Follow these simple steps:

Make sure the affected skin area is clean and dry before application.
Apply a thin film of the ointment to the affected area.
Rub it in completely and allow it to dry before dressing.
After 2 hours, expose the treated area to sunlight or UV light for a duration as advised by your doctor.
Always wash your hands thoroughly after applying the ointment.

Melanocyl Ointment is applied topically.

While using Melanocyl Ointment, you might experience a few side effects. These commonly include:

Skin irritation: You may notice some discomfort or sensitivity on the skin areas where the ointment is applied.
Hyperpigmentation: This refers to the darkening of treated skin areas, making them appear darker than your usual skin colour.
Dry skin: Your skin might feel parched or dehydrated.
Folliculitis: This condition involves inflammation of hair follicles, which could lead to small, red bumps or pimples.

In rare cases, some serious side effects could occur, such as:

Blistering or peeling skin
Swelling of face, lips, or tongue
Hives: These are itchy, red patches on the skin. .

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Melanocyl Ointment. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Below are some tips to manage a couple of common side effects:

Dry Skin: Applying a moisturiser to the treated areas can help manage this effect.
Skin Irritation: If your skin feels irritated after applying Melanocyl Ointment , try applying it at bedtime so that it can work overnight while you sleep.

Melanocyl Ointment contains two active ingredients:

Methoxsalen (0.75%): This ingredient is part of a group of medicines called psoralens that increase the skin’s sensitivity to UV radiation. Methoxsalen intercalates into DNA, and upon being activated by UVA light, it forms adducts that stimulate melanocytes and increase pigment production.
Aminobenzoic acid (2%): Known as PABA, this component absorbs UV light and stimulates melanocytes - the pigment-producing cells in your skin - thereby increasing skin pigmentation. PABA also provides some protection from UV light.

The combination of these two active ingredients, when used with controlled exposure to UV light, leads to gradual repigmentation of white patches caused by vitiligo.

Pregnancy

Caution is advised while applying Melanocyl Ointment if you are pregnant. It is best to consult your doctor before using this medicine.

Breastfeeding

Consult your doctor before using Melanocyl Ointment if you are breastfeeding. They can provide guidance on potential risks and benefits.

Alcohol

For topical applications like Melanocyl Ointment, interactions with alcohol are quite rare. Nevertheless, it's always a good idea to consult your doctor about it.

Liver

While liver health isn't usually a concern with topical applications, if you have any pre-existing liver conditions, it is advised to consult your doctor before using this medicine.

Kidney

Similar to liver health, kidney conditions are rarely affected by topical medicines like Melanocyl Ointment. However, if you have any kidney health issues, please consult your doctor.

Using Machines & Driving

Melanocyl Ointment is unlikely to affect your ability to drive or operate machinery. If you notice any unusual symptoms that might affect these activities, contact your doctor right away.

Allergy

If you are allergic to aminobenzoic acid, methoxsalen, or any other component of Melanocyl Ointment, avoid its use. Allergic reactions may include swelling of the face or tongue, difficulty breathing, or hives.

Children

Melanocyl Ointment is not recommended for use in children under 12 years of age. Always consult your doctor before applying this medicine for a child.

Older Patients

Older patients should apply Melanocyl Ointment under medical supervision as they may be more susceptible to its side effects. If you are above 70 years of age or have liver and kidney issues, discuss these concerns with your doctor before starting this medicine.

Drug-Drug Interactions

Melanocyl Ointment interacts with the following medicines:

Tetracycline Antibiotics: Medicines like doxycycline can enhance your skin's sensitivity to light, potentially increasing the risk of severe sunburns.
Sulfonamides: Medications such as sulfamethoxazole might increase photosensitivity, leading to enhanced skin reactions when combined with Melanocyl Ointment.
Thiazide Diuretics: Medicines like hydrochlorothiazide may heighten your skin's sensitivity to light, posing a risk of severe sunburns.

Drug-Food Interactions

No specific food interactions have been identified with Melanocyl Ointment.

Drug-Disease Interactions

Melanocyl Ointment interacts with the following diseases:

Skin Cancer: If you have a history of skin cancer, using Melanocyl Ointment could potentially lead to complications.
Photosensitivity Disorders: Diseases like lupus erythematosus or porphyria that increase sensitivity to light may be exacerbated by Melanocyl Ointment.
Skin Conditions: If you have compromised skin barrier due to conditions like psoriasis, usage of Melanocyl Ointment could potentially worsen your condition.

Daily Dose

The daily application of Melanocyl Ointment should be as recommended by your doctor. The doctor may alter the dosage based on various factors like how severe your condition is and how well you're responding to the medication. It's vital not to exceed the prescribed dose without consulting your doctor.

Over Dose

If you accidentally apply more Melanocyl Ointment than prescribed, you might experience some minor skin irritation or burning. Don't panic; wash off the excess ointment with water. If skin irritation persists or worsens, inform your doctor.

Missed Dose

If you forget to apply Melanocyl Ointment at the scheduled time, apply it as soon as you remember. But, if it's nearly time for your next application, skip the missed one and continue with your regular schedule. Never increase the quantity of application without consulting your doctor.

Store Melanocyl Ointment in a cool, dry place, ideally at room temperature between 20°-25°C.
Keep it away from direct sunlight and extreme heat or cold.
Ensure the tube is tightly closed to prevent air and moisture from entering.
Always keep this medicine out of reach of children.

Since Melanocyl Ointment is used for managing vitiligo, maintaining a balanced diet rich in vitamins (especially vitamin B12 and folic acid) can potentially aid in skin repigmentation.
Regular mild exercises under controlled sunlight exposure can help stimulate melanocytes, the cells responsible for skin colour, enhancing the effect of the ointment. Always consult your doctor about the most suitable exercise routine and sun exposure levels for you.

Fact Box

Drug Category	Melanocytes stimulator
Therapeutic Category	Anti vitiligo
Available Dosage Types	Ointment
Habit Forming	No
Ailment	Vitiligo, Hypopigmentation

What is Melanocyl Ointment used for?

Melanocyl Ointment is used to manage vitiligo, a skin condition where white patches appear due to loss of skin pigment. It's used with controlled UV light exposure.

How does Melanocyl Ointment work?

Melanocyl Ointment contains aminobenzoic acid and methoxsalen which stimulate melanocytes, the cells that produce skin pigment, leading to repigmentation when exposed to controlled UV light.

How should I apply Melanocyl Ointment?

Apply a thin film of Melanocyl Ointment on the affected areas, let it dry completely before clothing. After two hours, expose the treated area to controlled UV light.

What are the side effects of using Melanocyl Ointment?

Common side effects include skin irritation, redness, itching, burning sensation, and hyperpigmentation. Rare serious side effects like blistering or peeling skin require immediate medical attention.

Are there any precautions while using Melanocyl Ointment?

Avoid applying the ointment on injured or infected skin. Protect treated areas from sunlight by wearing clothing or applying sunscreen. Consult your doctor about your skin history.

Can I use other medications while using Melanocyl Ointment?

Certain medicines can increase photosensitivity and should be used cautiously with Melanocyl Ointment. Always inform your doctor about all current medications before starting treatment with Melanocyl Ointment.

How should I store Melanocyl Ointment?

Store Melanocyl Ointment at room temperature (20°-25°C), away from direct sunlight, heat and moisture. Keep it out of reach of children for safety reasons.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

20, Dr. E. Moses Road, Mahalaxmi, Mumbai, Maharashtra 400011

Country of origin: INDIA

References

Methoxsalen: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00553
Vitiligo: MedlinePlus Medical Encyclopedia. (n.d.). https://medlineplus.gov/ency/article/000831.htm
Para-aminobenzoic acid: MedlinePlus Medical Encyclopedia. (n.d.). https://medlineplus.gov/ency/article/002518.htm
PubChem. (n.d.). Methoxsalen. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/4114#section=Populations-at-Special-Risk

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