Met Xl Trio 50 Tablet 15

Met XL Trio 50 Tablet is used for the following:

• Management of high blood pressure in adults

• Use as initial therapy when multiple medicines are likely to be required to control blood pressure

• Management of angina pectoris, a type of chest pain caused by reduced blood flow to the heart

• Assisting the recovery process after a heart attack

When taking Met XL Trio 50 Tablet, follow these instructions:

• Swallow the tablet whole with a glass of water.

• Do not crush, chew, or divide the tablet.

• It can be taken with or without food.

Met XL Trio 50 Tablet is taken orally.

Met XL Trio 50 Tablet has three active ingredients, each with distinct beneficial actions:

• Metoprolol Succinate (50 mg): This cardioselective beta-1 adrenergic receptor blocker reduces heart rate and heart muscle contractility, leading to a decrease in cardiac output. The extended-release formulation allows for a more stable and prolonged effect compared to immediate-release metoprolol tablets.

• Cilnidipine (10 mg): This dihydropyridine calcium channel blocker reduces the influx of calcium ions into vascular smooth muscle cells. This results in a relaxation of these muscles (vasodilation), leading to a reduction in blood pressure. It also inhibits certain types of calcium channels in nerve terminals, suppressing the release of norepinephrine and providing sympathetic suppression.

• Telmisartan (40 mg): As an angiotensin II receptor blocker, telmisartan selectively inhibits the binding of angiotensin II to specific receptors in vascular smooth muscles and adrenal glands. This leads to vasodilation, reduced secretion of aldosterone, and ultimately lower blood pressure.

These three agents work together, providing comprehensive control of hypertension through varying mechanisms: calcium channel blockade, sympathetic suppression, beta-blockade, and RAAS inhibition. This results in a more effective and consistent blood pressure reduction compared to individual components.

• Store Met XL Trio 50 Tablet at a temperature below 30°C.

• Keep the medicine away from direct sunlight and moisture.

• Always ensure the medicine is out of reach of children.

• Since Met XL Trio 50 Tablet manages hypertension, reducing salt intake can help control blood pressure. So, aim for a low-salt diet which includes fresh fruits, vegetables, and lean proteins.

• Regular physical activity can also help lower blood pressure. Engage in light exercises most days of the week.