Metrogyl O 200500 Mg Tablet 10

Metrogyl O Tablet 10

J B Chemicals And Pharmaceuticals Ltd

Strip of 10 Units

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Composition

Metronidazole (500 Mg) + Ofloxacin (200 Mg)

Metrogyl O Tablet is a combination antibiotic used to manage bacterial and parasitic infections, including the teeth, lungs, gastrointestinal, urinary, genital, eye, and ear regions infections. It targets and eliminates the bacteria responsible for infections, reducing symptoms like watery stools, abdominal cramps, and dehydration. It is also used to treat dysentery, a severe form of diarrhea.

When prescribed, it is essential to complete the entire course of treatment as directed by your doctor for the optimal effectiveness of this medication. Some side effects may be noted with the use of this suspension, which should be timely informed to a doctor. Any allergy to this suspension, existing diseases and other ongoing medications should also be brought to the notice of your doctor before this suspension is prescribed to you.

Metrogyl O Tablet is used to manage the several health conditions, including:

Urinary tract infections: Manages bacterial infections causing discomfort and frequent urination.
Peritonitis: Manages peritonitis, which is the inflammation of the lining of the abdomen due to bacterial infection.
Eye and ear infections: Relieves symptoms like redness, itching, discharge, and pain.
Skin and soft tissue infections: Manages cellulitis, abscesses, and infected wounds.
Sexually transmitted infections: Manages gonorrhoea and chlamydia.
Respiratory infections: Manages bronchitis and pneumonia.
Vaginal infections: Manages bacterial vaginosis that causes itching, discharge, and discomfort.
Protozoan infections: Manages amoebiasis and giardiasis which cause diarrhoea.
Intra-abdominal infections: Manages bacterial invasion within the abdominal cavity.
Infections during surgical procedures: Manages postoperative or prophylactic.
Pelvic infections: This tablet is also effective in treating pelvic infections.
Foot ulcers in individuals with diabetes: This tablet can also be used to combat infections associated with these foot ulcers in diabetic patients.
Lung abscesses: It can also help treat lung abscesses (pus within the lung tissue).
Gynaecological infections: This tablet can also be used to manage gynaecological infections caused by susceptible bacteria and protozoa.
Parasitic Infections: It is useful in treating parasitic infections caused by parasites that enter the body through contaminated food or water. These infections can lead to symptoms like diarrhoea and stomach pain.

Directions for Use of Metrogyl O Tablet 10

Metrogyl O Tablet should be taken as prescribed by your doctor.
Swallow it with water, preferably after food, to prevent nausea.
Do not cut, break or chew the medicine.
It would be best to take it at a fixed time for optimal results.

Metrogyl O Tablet is taken orally.

Below are some common side effects of Metrogyl O Tablet:

Nausea: You may feel like vomiting or have an unsettled stomach.
Vomiting: You may throw up after taking the medicine.
Abdominal pain: This can occur as a discomfort or cramping sensation in the stomach area.
Headache: You may feel pain or discomfort in your head.
Dizziness: This may present as a feeling of lightheadedness or unsteadiness, potentially affecting balance.
Metallic taste in mouth: This could cause an unusual or strange taste sensation.
Loss of appetite: You may not feel hungry or have a reduced desire to eat.

Managing the Side Effects:

Most side effects are temporary and generally harmless and resolve on discontinuing the use of Metrogyl O Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are a few tips for managing the side effects of Metrogyl O Tablet:

Nausea: Eat small, frequent meals and avoid spicy or greasy foods.
Vomiting: Stay hydrated by sipping on clear fluids and avoid eating large meals.
Abdominal pain: Apply a warm compress to your stomach and try gentle stretching exercises.
Headache: Rest in a quiet, dark room and apply a cold compress to your forehead.
Dizziness: Avoid sudden movements and take breaks when feeling dizzy.
Metallic taste in mouth: Taking a sweet after the medicine might help mask this odd flavour.
Loss of appetite: Eat small, nutritious meals throughout the day and try incorporating foods with strong flavours that appeal to you.

The Metrogyl O Tablet contains the following components:

Metronidazole (500 mg): It is an antimicrobial agent that undergoes chemical changes inside the bacterial and protozoa cells that generate some compounds. These compounds interfere with DNA replication and cause damage to the genetic material of the microorganisms. As a result, ornidazole is effective against bacteria and protozoa.
Ofloxacin (200 mg): It is a fluoroquinolone antibiotic that inhibits the bacterial enzyme DNA gyrase. This enzyme is essential for DNA replication and repair. By interfering with this process, ofloxacin disrupts bacterial DNA synthesis and inhibits bacterial growth. This makes it effective against a broad spectrum of bacteria.

Pregnancy

Is it safe to use the Metrogyl O Tablet during pregnancy?

Metrogyl O Tablets are not suitable for pregnant women. Be cautious about its use, and consult your doctor for advice.

Breastfeeding

Is it safe to consume Metrogyl O Tablet during breastfeeding?

Metrogyl O Tablets are not suitable for breastfeeding women. Be cautious about its use, and consult your doctor for advice.

Alcohol

Is it safe to drink alcohol while taking Metrogyl O Tablet?

Metrogyl O Tablet should not be taken for at least 48 hours of consuming alcohol. Reactions similar to disulfiram with alcohol are seen when they are taken together. The symptoms are dizziness, flushing, headache and nausea.

Liver

Is it advisable to take Metrogyl O Tablet when experiencing liver problems?

Dosage adjustment may be required for patients who are suffering from liver disease. Use of Metrogyl O Tablet may also lead to liver damage. Be cautious about its use, and consult your doctor for advice.

Kidney

Is it advisable to consume Metrogyl O Tablet when experiencing kidney problems?

Dosage adjustment may be required for patients who are suffering from kidney disease. Be cautious about its use, and consult your doctor for advice.

Allergy

Are there any specific conditions that should be considered before taking the Metrogyl O Tablet ?

Allergic reactions are seen after the first dose administration of Metrogyl O Tablet. Do not use the tablet if you are allergic to metronidazole, ofloxacin, or any other component of Metrogyl O Tablet. Be cautious about its use, and consult your doctor for advice.

Children

Is Metrogyl O Tablet suitable for infants or children?

Metrogyl O Tablet is not intended for children below 18 years of age.

Older Patients

Is Metrogyl O Tablet suitable for older patients?

Older patients with kidney dysfunction, liver impairment, and heart problems should take this tablet cautiously. Elderly patients taking corticosteroids should also cautiously take this tablet. They might also be taking other medications that can interact with Metrogyl O Tablet. Consult your doctor and discuss your prescription medications before taking this tablet.

Drug-Drug Interactions

Nutritional supplements may interact with Metrogyl O Tablet and reduce the absorption of the Metrogyl O Tablet.
Anti-inflammatory drugs like theophylline and Fenbufen may interact with Metrogyl O Tablet and cause decreased ability to defend against seizure occurrence.
Medicines acting on kidney function like probenecid may interact with Metrogyl O Tablet and cause increased effect of Metrogyl O tablet on humans; dosage adjustment may be required.
Anti-arrhythmic and anti-depressant drugs may interact with Metrogyl O and prolong the QT Interval.
Vitamin K antagonists like warfarin, when interacted with Metrogyl O tablets, may cause increased bleeding duration.

Drug-Disease Interactions

Blood dyscrasias may worsen on taking Metrogyl O Tablet. Consult your doctor for advice.
Bacterial vaginosis may worsen on taking Metrogyl O Tablet. Consult your doctor for advice.
Seizures may worsen on taking Metrogyl O Tablet. Consult your doctor for advice.
Conditions like haemodialysis, gonococcal infection and kidney function should be monitored when on Metrogyl O Tablets as it may worsen on taking Metrogyl O Tablets. Consult your doctor for advice.
Porphyria as it may worsen on taking Metrogyl O Tablet. Consult your doctor for advice.

Daily Dose

The recommended daily dose of Metrogyl O Tablets should be strictly per the doctor's prescription. The dosage may change based on individual factors such as the severity of the condition and response to treatment. It is important to follow the prescribed dosage and not exceed it without consulting your doctor.

Over Dose

If you or someone else takes an excessive amount of Metogyl O Tablet by accident, it is essential to take the patient to the nearest doctor. The overdose symptoms include nausea, vomiting, dizziness, impaired consciousness, drowsiness and convulsions in seizures.

Missed Dose

If you forget to take the dose of the Metrogyl O Tablet, take it as soon as you remember. If the next dose is near, skipping the missed dose and resuming your regular dosage pattern is recommended.

Store the Metrogyl O Tablet at room temperature (15-25ºC).
Please protect it from light and moisture.
Keep Metrogyl O Tablets away from children.
Do not use the Metrogyl O Tablet after the expiry date has passed.

The Metrogyl O tablets are indicated for diarrhoea caused by mixed bacteria infections. Inform the doctor if the diarrhoea and its symptoms do not reduce after taking it for two days.
If you feel dizzy and drowsy, do not indulge in activities that require focus.
Do inform the doctor if you experience pain in joints, tingling sensation and feel numb

Fact Box

Drug Category	Antibiotics
Therapeutic Category	Antibacterial and Antiparasitic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Mixed diarrhoea

What is Metrogyl O tablet used for?

Metrogyl O Tablet is a combination of Metronidazole and Ofloxacin, used to treat various bacterial and parasitic infections, including gastrointestinal, urinary tract, and genital infections. It is also effective for managing dysentery and other infections caused by harmful bacteria and parasites.

Is Metrogyl O tablet an anti-fungal?

The Metrogyl O Tablet is a combination of both anti-fungal and anti-bacterial medicine. It contains metronidazole, which is used for infections caused by fungi.

What class of antibiotic is Metrogyl O tablet?

Metrogyl O belongs is a gastrointestinal antibiotic.

Is Metrogyl O tablet good for bacterial infections?

Yes, Metrogyl O Tablet is good for bacterial infections.

Does the Metrogyl O tablet work immediately?

The Metrogyl O Tablet takes more than 2-4 days to show the complete effect. The immediate effect of the medicine is seen within 1-2 hours. However, the response varies from one individual to another individual.

Last Updated On 19 Nov. 2024 | 9:40AM (IST)

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 6 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 11 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

Cnergy, Appasaheb Marathe Marg, Century Bazaar, Prabhadevi, Mumbai, Maharashtra 400025

Country of origin: INDIA

References

Therapies at JB. (2022, September 1). JB Pharma. https://jbpharma.com/our-therapies/. Metrogyl-O-Tablets_PI_India_October-2021
Metronidazole. (n.d.). Medlineplus.Gov. (Retrieved December 30 2023). https://medlineplus.gov/druginfo/meds/a689011.html
Ofloxacin. (n.d.). Medlineplus.Gov. (Retrieved December 30 2023). https://medlineplus.gov/druginfo/meds/a691005.html
Nayagam, A. T., Smith, M. D., Ridgway, G. L., Allason-Jones, E., Robinson, A. J., & Stock, J. (1992). Comparison of ofloxacin and metronidazole for the treatment of bacterial vaginosis. International Journal of STD & AIDS, 3(3), 204–207. https://doi.org/10.1177/095646249200300309

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