Mext F 751 Mg Tablet 28

Mext 7.5 F Tablet 28

Wallace Pharmaceuticals Ltd.

Strip of 28 Units

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MRP ~~₹87~~

₹71.34

₹3.11/Units

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Composition

Folic Acid (1 Mg) + Methotrexate (7.5 Mg)

Mext 7.5 F Tablet is primarily used to manage rheumatoid arthritis, a chronic autoimmune disorder that affects the joints. It belongs to a class of medicines known as antimetabolites, which have anti-inflammatory and immunosuppressive properties.

This medicine is also utilised in managing certain types of psoriasis, a skin condition characterised by red, scaly patches. Psoriasis can be difficult to control, but Mext 7.5 F Tablet aids in managing severe cases that are not responsive to other therapies.

Before starting this medicine, it's crucial to consult your doctor for the correct dosage and frequency. Inform your doctor about any pre-existing conditions or ongoing medications you're taking. If you experience any side effects while on this medication, notify your doctor immediately. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

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Mext 7.5 F Tablet is used for the following:

Management of rheumatoid arthritis: This medicine helps to decrease pain, swelling, and stiffness in the joints.
Control of severe psoriasis: It is effective in managing severe forms of psoriasis that do not respond adequately to other therapies.

Directions for Use of Mext 7.5 F Tablet 28

Take Mext 7.5 F Tablet in the following way:

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
You can take it with or without food.
Aim to take your medicine at the same time each day for consistent effect.
Avoid taking more than the recommended dose without consulting your doctor.

Mext 7.5 F Tablet is taken orally.

Taking Mext 7.5 F Tablet may lead to the following common side effects:

Nausea
Vomiting
Abdominal discomfort
Fatigue: This refers to a feeling of extreme tiredness or weakness.
Headache
Dizziness: This can cause you to feel unsteady, as if you're moving, spinning or floating, even when you're standing still.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Mext 7.5 F Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are two tips for managing common side effects:

Nausea: If you feel nauseous after taking this medicine, try taking it with food or milk.
Abdominal discomfort: Taking Mext 7.5 F Tablet after meals could help lessen this effect.

Mext 7.5 F Tablet contains two active ingredients:

Methotrexate (7.5 mg): This component acts by inhibiting an enzyme called dihydrofolate reductase in your body. This interference with DNA synthesis, repair, and cellular replication decreases the activity of the immune system in cases of rheumatoid arthritis, reducing inflammation and joint stiffness. In psoriasis, methotrexate slows down the rapid growth of skin cells, helping control the formation of scaly patches on the skin.
Folic acid (1 mg): A member of the B-vitamin family, folic acid plays a vital role in forming healthy cells, particularly red blood cells. In this combination, folic acid is included to prevent folate deficiency that can be caused by methotrexate therapy.

Pregnancy

Mext 7.5 F Tablet is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Mext 7.5 F Tablet is contraindicated for breastfeeding/lactating women. Consult your doctor to understand the potential risks and benefits.

Alcohol

While taking Mext 7.5 F Tablet, it's best to avoid alcohol as it may increase the risk of liver problems. Always consult your doctor for advice on this matter.

Liver

Caution is advised while taking Mext 7.5 F Tablet in case of mild to moderate liver impairment. It is not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting this medicine.

Kidney

If you have a history of kidney problems, it's advisable to consult your doctor before starting Mext 7.5 F Tablet, as it may affect kidney function.

Using Machines & Driving

Mext 7.5 F Tablet may cause fatigue and dizziness which could affect your ability to operate machinery or drive safely. Be cautious and discuss these potential effects with your doctor.

Allergy

Avoid using Mext 7.5 F Tablet if you're allergic to methotrexate or folic acid, or any other ingredients in the medicine. Inform your doctor about any known allergies before starting this medicine.

Children

Caution is advised when giving this medicine to children under 18 years of age.

Older Patients

Older patients should take Mext 7.5 F Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Mext 7.5 F Tablet is known to interact with the following medications:

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Medicines like ibuprofen and naproxen can interact with Mext 7.5 F Tablet, potentially reducing the effectiveness of the tablet and increasing the risk of side effects.
Antibiotics: Certain antibiotics such as ciprofloxacin, levofloxacin, and trimethoprim/sulfamethoxazole may increase the levels of methotrexate in your body, potentially leading to toxicity.
Proton Pump Inhibitors: Medicines like omeprazole and lansoprazole can interfere with methotrexate elimination from your body, increasing its levels and potentially causing toxic effects.

Drug-Food Interactions

Consumption of high-fibre foods may decrease the absorption of folic acid from Mext 7.5 F Tablet.

Drug-Disease Interactions

Mext 7.5 F Tablet is known to have following disease interactions:

Liver disease: If you have liver disease, taking Mext 7.5 F Tablet could potentially worsen your condition due to the methotrexate it contains.
Kidney disease: Patients with kidney disease should exercise caution as methotrexate could potentially build up in your body due to decreased kidney function, leading to toxicity.
Immunodeficiency disorders: People with immunodeficiency disorders should be careful when taking Mext 7.5 F Tablet as it can suppress your immune system further due to its methotrexate component.

Daily Dose

The daily dose of Mext 7.5 F Tablet is determined by your doctor and depends on factors like the severity of your condition and how you respond to the medication. It's important to adhere to the prescribed dosage and not exceed it without consulting your doctor.

Over Dose

If you accidentally take more Mext 7.5 F Tablets than prescribed, you may experience symptoms like nausea, vomiting, and abdominal discomfort. Do not panic but inform your doctor about this.

Missed Dose

If you forget to take your Mext 7.5 F Tablet, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and resume your regular schedule. Never increase your dosage without consulting your doctor.

Keep Mext 7.5 F Tablet in a cool, dark and dry place.
Protect it from excessive light and moisture.
Always keep it out of reach of children.
Ensure you use the medicine before the expiry date mentioned on the packaging.

For managing rheumatoid arthritis: Regular low-impact exercises like swimming or walking can help increase your joint flexibility.
For managing psoriasis: Maintaining a balanced diet rich in omega-3 fatty acids found in fish and nuts may help reduce inflammation and manage symptoms.

Fact Box

Drug Category	Antimetabolite
Therapeutic Category	Antirheumatic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Rheumatoid Arthritis, Psoriasis

What Is the Mext 7.5 F Tablet Used For?

This medicine is used to manage rheumatoid arthritis and certain types of severe psoriasis that don't respond well to other therapies.

How Does Mext 7.5 F Tablet Work?

It contains methotrexate, which reduces the immune system's activity and slows skin cell growth, and folic acid, which prevents folate deficiency.

How Should I Take Mext 7.5 F Tablet?

The tablet should be swallowed whole with water, with or without food. Please follow your doctor's instructions carefully.

Can I Use the Mext 7.5 F Tablet If I'm Pregnant or Breastfeeding?

No, methotrexate can cause birth defects and is found in breast milk, so it's not safe during pregnancy or breastfeeding.

What Should I Do If I Miss a Dose of Mext 7.5 F Tablet?

If you miss a dose, take it as soon as you remember unless it's almost time for the next dose. Always consult your doctor.

What Are the Side Effects of Mext 7.5 F Tablet?

Common side effects include nausea, vomiting, abdominal discomfort, fatigue, headache, dizziness, and increased risk of infections.

Can I Take Other Medicines While Using Mext 7.5 F Tablet?

Some medicines interact with this medicine. Always tell your doctor about all other medications you're taking.

Certified Content

Written by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

T1/B NATIONAL PARKGULBAI TEKRA AHMEDABAD GJ 380015 IN

Country of origin: INDIA

References

West-Ward Pharmaceuticals Corp. (2020). Highlights of prescribing information. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/040054s015,s016,s017.pdf
Methotrexate: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00563
Merrell, B. J., & McMurry, J. P. (2023, August 8). Folic acid. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK554487/
Folic acid: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00158

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