Minirin 02 Mg Tablet 30

Minirin 0.2mg Tablet 30

Ferring Pharmaceuticals

Strip of 30 Units

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Composition

Desmopressin (0.2 Mg)

Minirin 0.2mg Tablet is typically utilised for the management of central diabetes insipidus and nocturnal enuresis, also known as bedwetting. This medicine falls into the category of synthetic analogues of the natural antidiuretic hormone.

This tablet also efficiently manages nocturia in adults up to age 65. This condition involves excessive urination at night that surpasses the bladder's capacity, a common issue in older adults.

Before starting this medication, a thorough consultation with your doctor is crucial to determine the most suitable dosage and frequency for you. If you have any ongoing health issues or are currently on any other medication, it's essential to inform your doctor about them. In case you notice any side effects while on this medication, do report them to your doctor without delay. Lastly, for optimal outcomes, it's important to continue taking this medicine for the duration prescribed by your doctor.

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Minirin 0.2mg Tablet is used for the following:

Managing central diabetes insipidus, a condition where the body produces excessive diluted urine due to lack of vasopressin
Helping to control persistent bedwetting in children over the age of 5
Reducing excessive urination during night-time in adults up to age 65

Directions for Use of Minirin 0.2mg Tablet 30

Follow the dosage and timing instructions provided by your doctor precisely.
Do not change or exceed the prescribed dose without consulting your doctor.
Consult your doctor before discontinuing the medication; do not stop taking it without their guidance.
Adhere to the dietary recommendations given by your doctor.

Minirin 0.2mg Tablet is taken orally.

Minirin 0.2mg Tablet may have the following common side effects:

Headache
Nausea, abdominal cramps
Flushing: This is a warm feeling that can often be accompanied by reddening of the skin.
Dizziness
Nasal congestion

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Minirin 0.2mg Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea, abdominal cramps: Try taking Minirin 0.2mg Tablet with food to help manage these symptoms.
Flushing: If you experience this warm feeling, it might help to take the tablet in a cooler environment or at night.

Minirin 0.2mg Tablet contains desmopressin (0.2 mg), which has the following effects on your body:

Vasopressin Analogue: Desmopressin acts as a synthetic analogue of vasopressin, a natural antidiuretic hormone present in your body.
Increasing Water Reabsorption: By binding to V2 receptors in your kidneys' collecting ducts, desmopressin enhances water permeability and reabsorption.
Reducing Urine Volume: The increased water reabsorption leads to concentrated urine and reduced urine volume. This antidiuretic effect makes it useful for managing conditions like central diabetes insipidus and nocturnal enuresis/nocturia.

Pregnancy

Your doctor should guide you on the use of Minirin 0.2mg Tablet during pregnancy. It should be used only if the benefits outweigh the risks.

Breastfeeding

Those who are nursing a child must use this medicine with caution. It's crucial to consult your doctor before starting Minirin 0.2mg Tablet as it might pass into breast milk.

Alcohol

The interaction between the consumption of alcohol and Minirin 0.2mg Tablet is negligible. However, you can consult your doctor for advice on this matter.

Liver

If you have any liver issues, it's important to take Minirin 0.2mg Tablet under medical supervision. Discuss your liver health with your doctor before starting this medication.

Kidney

Minirin 0.2mg Tablet is not recommended if you have kidney disease or impaired ability to excrete water. Discuss any kidney health issues with your doctor before taking this medicine.

Using Machines & Driving

This medicine may cause drowsiness, which could affect your ability to operate machines or drive. Exercise caution if you need to do these activities while taking Minirin 0.2mg Tablet.

Allergy

Avoid this medicine if you have known hypersensitivity to desmopressin, the active ingredient in Minirin 0.2mg Tablet. Your doctor can help identify alternative medicines if necessary.

Children

Be cautious when giving Minirin 0.2mg Tablet to children under 18 years of age. It's recommended to consult a doctor before administering this medicine to a child.

Older Patients

Older patients might be more prone to side effects of this medicine, so they should use it under medical supervision. It's recommended that patients above 70 years of age discuss their overall health status with their doctor before starting Minirin 0.2mg Tablet.

Drug-Drug Interactions

Minirin 0.2mg Tablet interacts with the following medicines:

Tricyclic Antidepressants: Medicines like amitriptyline or nortriptyline may enhance the water-retaining effects of desmopressin in Minirin 0.2mg Tablet, potentially increasing the risk of hyponatremia (low blood sodium).
SSRIs: Serotonin reuptake inhibitors, such as fluoxetine and sertraline, could also potentiate the antidiuretic effect of desmopressin, leading to an increased risk of water retention and hyponatremia.
Vasopressors: Medications like norepinephrine can have their blood pressure raising effects boosted when used with Minirin 0.2mg Tablet.

Drug-Food Interactions

There are no known food interactions with Minirin 0.2mg Tablet.

Drug-Disease Interactions

Minirin 0.2mg Tablet interacts with the following diseases:

Heart Failure: Patients with heart failure should exercise caution as Minirin 0.2mg Tablet could exacerbate their condition due to its antidiuretic effects.
Uncontrolled Hypertension: Increased blood pressure can occur in patients using Minirin 0.2mg Tablet due to potential interaction with vasopressors.
Kidney Disease: In patients with kidney disease, there's an increased risk of fluid retention and electrolyte imbalance when using Minirin 0.2mg Tablet.
SIADH (Syndrome of Inappropriate ADH Secretion): Patients with this condition may experience worsened symptoms due to additional antidiuretic hormone activity from the Minirin 0.2mg Tablet.

Daily Dose

The daily dose of Minirin 0.2mg Tablet is determined by your doctor, based on factors like the severity of your condition and how you respond to the medicine. It's crucial to follow the prescribed dosage and not alter it without your doctor's guidance.

Over Dose

If you accidentally take more than the prescribed dose of Minirin 0.2mg Tablet, you may experience common side effects like headache, nausea, and dizziness in a more severe form. If such symptoms persist or worsen, inform your doctor.

Missed Dose

If you forget to take a dose of Minirin 0.2mg Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed dose and resume your regular dosage schedule. Always consult your doctor before making any changes to your dosage.

Store Minirin 0.2mg Tablet at a room temperature below 25°C.
Protect this medication from moisture to maintain its efficacy.
Always keep Minirin 0.2mg Tablet out of the reach of children.
Make sure you use the medicine before its expiry date.

For managing central diabetes insipidus, ensure you maintain a well-balanced diet with enough protein, fibre, and healthy fats. This helps your body regulate fluid balance.
If you are using Minirin 0.2mg Tablet for nocturnal enuresis or nocturia, avoid drinking large amounts of fluids in the evening. This can help reduce the need to pass urine during the night.

Fact Box

Drug Category	Synthetic Vasopressin Analog
Therapeutic Category	Antidiuretic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Central Diabetes Insipidus, Nocturnal Enuresis, Nocturia

What conditions is Minirin 0.2mg Tablet used to manage?

Minirin 0.2mg Tablet is used to manage central diabetes insipidus, primary nocturnal enuresis (bedwetting), and nocturia in adults up to age 65.

How does Minirin 0.2mg Tablet work?

Minirin 0.2mg Tablet contains desmopressin which works by increasing water reabsorption in the kidneys, thereby reducing urine production and managing the symptoms of certain conditions.

Can I take Minirin 0.2mg Tablet with food?

Yes, you can take Minirin 0.2mg Tablet with or without food as per your doctor's instructions.

What if I miss a dose of Minirin 0.2mg Tablet?

If you miss a dose, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one. Do not double dose.

What are the potential side effects of Minirin 0.2mg Tablet?

Common side effects include headache, nausea, flushing, dizziness, and nasal congestion. Serious but rare side effects can include severe allergic reactions and low blood sodium levels.

Is it safe to take Minirin 0.2mg Tablet during pregnancy or while breastfeeding?

The safety of Minirin 0.2mg Tablet during pregnancy is not established. It should be used only if benefits justify potential risks. Caution is advised for breastfeeding women.

Are there any precautions I need to follow while taking Minirin 0.2mg Tablet?

Yes, limit fluid intake during treatment to prevent water retention and low blood sodium levels. Also, use caution when driving or operating machinery as it may cause drowsiness.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

References

Ferring Pharmaceuticals Inc. (2019). Highlights of prescribing information. In Desmopressin Acetate Tablets. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/021795s006lbl.pdf
Ferring Pharmaceuticals Inc. (2022). Highlights of prescribing information [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/018938s039lbl.pdf
Ferring Pharmaceuticals Inc. (2018). Highlights of prescribing information - DDAVP nasal spray. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/017922s046lbl.pdf
DailyMed - DESMOPRESSIN ACETATE tablet. (n.d.). https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=9fba5e90-f541-4588-a5e9-b56198f17e87
Desmopressin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00035

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