Minirin 02 Mg Tablet 30

Minirin 0.2mg Tablet 30

Ferring Pharmaceuticals

Strip of 30 Units

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Composition

Desmopressin (0.2 Mg)

Minirin 0.2mg Tablet is primarily used to manage Central Diabetes Insipidus (CDI), a rare disorder that causes excessive urine production. It belongs to a class of medicines known as synthetic analogues of the natural antidiuretic hormone vasopressin.

In addition to managing CDI, this medication is also utilised to manage bedwetting in children over the age of 5 when other treatments have not been effective. It helps reduce nighttime urine production, thereby aiding in controlling this condition.

Before starting on this tablet, it's crucial that you consult your doctor who will guide you on the correct dosage and frequency of use. Do let your doctor know about any pre-existing conditions or ongoing medications. If you observe any side effects while using this tablet, inform your doctor immediately. For optimal results, continue taking the medication for the duration prescribed by your doctor.

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Minirin 0.2mg Tablet is used for:

Managing Central Diabetes Insipidus, a condition resulting in excessive urine production due to vasopressin deficiency.
Controlling Bedwetting (Nocturnal Enuresis) in children over 5 years old, when other treatments have been unsuccessful.

Directions for Use of Minirin 0.2mg Tablet 30

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
This medicine can be taken with or without food.
If you have trouble swallowing tablets, there's also a melt formulation that dissolves under the tongue.
Always follow your doctor's advice regarding the timing and frequency of taking this medicine.

Minirin 0.2mg Tablet is taken orally.

Possible side effects of Minirin 0.2mg Tablet include:

Headache
Nausea
Abdominal cramps
Flushing: This means you might feel a sudden warmth and redness on your face or upper body.
Allergic reactions: Though rare, these can occur and could involve symptoms like rash, itching or swelling particularly on the face, throat or tongue.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Minirin 0.2mg Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips for managing potential side effects:

Nausea: Try to take Minirin 0.2mg Tablet with food to help minimise this effect.
Abdominal Cramps: If you experience stomach discomfort after taking the medicine, consider taking it after a meal.

Minirin 0.2mg Tablet contains desmopressin (0.2 mg). Here's how it works:

Vasopressin Receptor Activation: Desmopressin activates vasopressin receptors in the kidney tubules.
Increased Water Permeability: Once these receptors are activated, water permeability in the kidney tubules increases.
Boosted Water Reabsorption: The increased water permeability promotes water reabsorption from urine back into the bloodstream.
Decreased Urine Volume: As a result of increased water reabsorption, there is a decrease in urine volume.
Enhanced Urine Concentration: Alongside reducing urine volume, desmopressin also aids in increasing the concentration of urine.

Pregnancy

Minirin 0.2mg Tablet is categorised as a Pregnancy Category B medicine. It's recommended to exercise caution while taking this medicine if you are pregnant. Your doctor can provide the best advice based on your individual situation.

Breastfeeding

It's best to consult your doctor before taking this medicine if you're breastfeeding.

Alcohol

Always consult your doctor for guidance on your alcohol intake while on this medication.

Liver

Caution is advised regarding the use of Minirin 0.2mg Tablet in patients with liver problems. It's recommended to consult your doctor before starting this medicine.

Kidney

Minirin 0.2mg Tablet is contraindicated for individuals with kidney failure. If you have any kidney conditions, it's essential to discuss them with your doctor before starting this medication.

Using Machines & Driving

Minirin 0.2mg Tablet might affect mental alertness in some cases. Until you know how this medicine affects you, be cautious when driving or operating machinery.

Allergy

If you are allergic to desmopressin or any other ingredients present in Minirin 0.2mg Tablet, avoid taking this medicine.

Children

Although Minirin 0.2mg Tablet can be prescribed for bedwetting in children over 5 years old, it should always be administered under medical supervision and after consultation with a doctor.

Older Patients

Older patients may be more susceptible to side effects of Minirin 0.2mg Tablet, especially hyponatremia (low blood sodium levels). If you are over 70 years old, consult your doctor before starting this medicine. They will guide you based on your health status.

Drug-Drug Interactions

Minirin 0.2mg Tablet interacts with the following medicines:

Diuretics: Medicines like furosemide and hydrochlorothiazide, when taken with Minirin 0.2mg Tablet, can increase the risk of low sodium levels in your blood (hyponatremia).
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): NSAIDs like ibuprofen and naproxen can enhance the effect of Minirin 0.2mg Tablet, leading to an increased risk of water retention and hyponatremia.

Drug-Food Interactions

Certain food items can interact with Minirin 0.2mg Tablet. It's important to follow your doctor's guidance on dietary restrictions while taking this medicine.

Drug-Disease Interactions

Minirin 0.2mg Tablet interacts with the following diseases:

Heart disease: Patients with heart disease should exercise caution as Minirin 0.2mg Tablet could exacerbate their condition.
Kidney disease: People with kidney issues might experience an increase in side effects due to decreased medicine clearance.
Hyponatremia: Patients with a history of low sodium levels in their blood should be closely monitored while taking this medication as it could worsen their condition.

Daily Dose

You should take the daily dose of Minirin 0.2mg Tablet as advised by your doctor. This dosage could vary based on factors such as your health condition and how you respond to the medicine. It's crucial not to exceed the prescribed dosage without consulting your doctor.

Over Dose

Overdosing on Minirin 0.2mg Tablet may lead to symptoms like headache, nausea, and weight gain. If you suspect that you've taken more than the prescribed dose, inform your doctor about it straight away.

Missed Dose

If you forget to take your Minirin 0.2mg Tablet, take it as soon as you remember. However, if it's almost time for the next dose, skip the missed one and continue with your regular schedule. Never increase your dosage without discussing it with your doctor first.

Store your Minirin 0.2mg Tablet at room temperature, ideally below 25°C.
Shield it from light and moisture, so keep the container tightly closed.
Remember to keep the medicine out of reach of children.
Make sure you use the tablet before its expiry date.

If you're managing Central Diabetes Insipidus (CDI), avoid excessive water intake. This condition causes your body to produce large amounts of urine, and drinking too much water can worsen this symptom.
For those using Minirin 0.2mg Tablet to manage bedwetting, reduce fluid intake before bedtime. This can help decrease nighttime urine production.

Fact Box

Drug Category	Antidiuretic
Therapeutic Category	Hormone Replacement
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Central Diabetes Insipidus, Bedwetting

What is the Minirin 0.2mg Tablet used for?

Minirin 0.2mg Tablet is primarily used to manage Central Diabetes Insipidus and bedwetting in children over 5 years old.

How does the Minirin 0.2mg Tablet work?

Minirin 0.2mg Tablet contains desmopressin, which acts on the kidneys to reduce urine volume by promoting water reabsorption back into the bloodstream.

Can I take Minirin 0.2mg Tablet with or without food?

Yes, you can take this medicine with or without food. It should be swallowed whole with a glass of water.

What are some common side effects of Minirin 0.2mg Tablet?

Common side effects include headache, nausea, abdominal cramps, flushing and in rare cases, allergic reactions.

Who should not take Minirin 0.2mg Tablet?

It is contraindicated for those with kidney failure, hyponatremia (low blood sodium levels), excessive thirst, or Syndrome of inappropriate ADH secretion (SIADH).

Can pregnant women take Minirin 0.2mg Tablet?

Minirin 0.2mg Tablet is a Pregnancy Category B medicine and does not appear to increase risks in pregnancy. However, consult your doctor before use.

What happens in case of an overdose of Minirin 0.2mg Tablet?

Overdose can cause severe hyponatremia and fluid retention leading to symptoms like headache, nausea, weight gain, and convulsions. If suspected, contact a poison control centre immediately.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

509, 510 The Capital, Bandra Kurla Complex, Bandra East, Mumbai, Maharashtra 400051

Country of origin: INDIA

References

Ferring Pharmaceuticals Inc. (2019). Highlights of prescribing information. In Desmopressin Acetate Tablets. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/021795s006lbl.pdf
Ferring Pharmaceuticals Inc. (2022). Highlights of prescribing information [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/018938s039lbl.pdf
Ferring Pharmaceuticals Inc. (2018). Highlights of prescribing information - DDAVP nasal spray. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/017922s046lbl.pdf
DailyMed - DESMOPRESSIN ACETATE tablet. (n.d.). https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=9fba5e90-f541-4588-a5e9-b56198f17e87
Desmopressin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00035

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