Mirabig 25 Tablet 10

Msn Laboratories Ltd

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Composition

Mirabegron (25 Mg)

Strength:

50 MG 25 MG

Mirabig Tablet is primarily used to manage symptoms of overactive bladder (OAB) in adults. This medicine is part of a group known as beta-3 adrenergic agonists, which are known for their role in managing urinary conditions.

This medicine also helps manage urinary urgency, where you feel a sudden, compelling need to urinate. It can also aid in controlling urinary frequency, where you need to urinate often, and urge incontinence, where there is an involuntary leakage of urine accompanied by urgency.

It's crucial that you take this medicine as directed by your doctor. Before starting this medication, inform your doctor about any pre-existing conditions or ongoing medications you may be taking. If you notice any side effects while on this medicine, notify your doctor immediately. Remember to continue taking the medicine for the duration prescribed by your doctor for optimal results.

Mirabig Tablet is useful in the following conditions:

Management of overactive bladder symptoms in adults: This includes an urgent need to urinate, frequent urination, and involuntary leakage of urine due to a sudden urge to urinate.

Directions for Use of Mirabig 25 Tablet 10

Follow the steps below while taking Mirabig Tablet:

Swallow the tablet whole with water.
Do not chew, divide, or crush the tablet.
You can take this medicine with or without food.
Always follow your doctor's advice regarding the dose and duration of use.
If you have any questions about how to take this medicine, please consult your doctor.

Mirabig Tablet is taken orally.

Mirabig Tablet may have the following common side effects:

Hypertension
Urinary Tract Infection
Headache
Nasopharyngitis: This is inflammation of the nasal passages and the upper part of the throat, often leading to a common cold.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Mirabig Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some simple ways to manage a couple of common side effects:

Headache: Ensure proper rest in a dimly lit room to avoid getting headaches after taking this medication.
Urinary Tract Infection: Increase your water intake to help flush out bacteria from your urinary system.

Mirabig Tablet contains Mirabegron (25 mg), which works in your body through the following mechanisms:

Stimulates Beta-3 Adrenergic Receptors: Mirabegron works by selectively acting on the beta-3 adrenergic receptors in your bladder muscle. These receptors are responsible for controlling the relaxation and contraction of your bladder muscle.
Enhances Bladder Capacity: When Mirabegron stimulates these receptors, it leads to the relaxation of your bladder muscle during the storage phase of urine. As a result, your bladder's capacity to hold urine increases, which helps reduce the symptoms of OAB such as urgency, frequency, and incontinence.
Avoids Side Effects of Anticholinergics: Since Mirabegron targets the beta-3 receptors and not the muscarinic receptors targeted by anticholinergic medicines, it avoids many of the side effects associated with anticholinergics.

Pregnancy

Mirabig Tablet should be used during pregnancy only if the benefits outweigh any potential risks to the unborn baby. It is best to consult your doctor before taking this medicine.

Breastfeeding

It's not known if Mirabig Tablet passes into breast milk. It's important to discuss with your doctor whether to discontinue nursing or stop using this medicine.

Alcohol

No specific information is available on the interaction of Mirabig Tablet with alcohol. It's always a good idea to consult your doctor for clarity.

Liver

For those with moderate liver impairment, caution is advised when taking Mirabig Tablet. The medicine is not suitable for individuals with severe liver disease. Always discuss your liver condition with your doctor before starting this medication.

Kidney

Patients with severe kidney impairment should exercise caution while taking Mirabig Tablet. This medication isn't recommended for individuals suffering from end-stage renal disease. Make sure you inform your doctor about any kidney problems before starting this medicine.

Using Machines & Driving

There's no specific information available about the impact of Mirabig Tablet on driving or operating machinery. As a precautionary measure, it's advisable to avoid such activities until you know how this medicine affects you.

Allergy

Mirabig Tablet is not suitable for people who have known hypersensitivity towards mirabegron or any other ingredients of the tablet. If you're aware of any allergies, discuss them with your doctor before starting this medicine.

Children

The safety and effectiveness of Mirabig Tablet in children under 18 years of age have not been established yet. Always consult your doctor before giving any medicine to a child.

Older Patients

Mirabig Tablet can be used by elderly patients without any specific dose adjustment. However, as older patients might have liver and kidney issues or might be on other medication, it's always wise to discuss your health status with your doctor before starting this medicine.

Drug-Drug Interactions

Mirabig Tablet interacts with the following medicines:

Antifungals: Medicines like itraconazole and ketoconazole can increase the levels of mirabegron in your blood, raising the risk of side effects such as increased heart rate or high blood pressure.
Antibiotics: Clarithromycin and erythromycin can also raise the blood levels of mirabegron, which may increase the likelihood of side effects like dizziness or palpitations.
Anticholinergics: Taking mirabegron with other anticholinergic medicines, such as oxybutynin or tolterodine, can increase the risk of urinary retention, dry mouth, constipation, and blurred vision.
Blood Pressure Medications: If you take mirabegron with atenolol, your blood pressure could be affected, requiring monitoring for any changes.
Diuretics: Diuretics like spironolactone or amiloride might cause fluid retention or electrolyte imbalances when combined with mirabegron.

Drug-Food Interactions

There are no specific food items known to interact with Mirabig Tablet. Therefore, this medicine may be taken with or without food.

Drug-Disease Interactions

Mirabig Tablet interacts with the following diseases:

Hypertension: Mirabig Tablet can increase blood pressure levels. So if you have high blood pressure, you should monitor your levels regularly while on this medication.
Bladder Outlet Obstruction: Caution should be exercised while using this medicine as it may increase the risk of urinary retention in patients with bladder outlet obstruction.

Daily Dose

Take the daily dose of Mirabig Tablet as prescribed by your doctor. The prescribed dosage can depend on various factors, such as the severity of your condition and how your body responds to the medication. Always stick to the dosage recommended by your doctor.

Over Dose

If you accidentally consume more than your prescribed dose, you might feel an increase in heart rate or experience palpitations. No need to panic, but do inform your doctor about it.

Missed Dose

Should you forget to take Mirabig Tablet at the scheduled time, take it as soon as you remember. If it's almost time for the next dose, skip the missed one and continue with your regular schedule. Never take an extra dose without consulting your doctor.

Store Mirabig Tablet in its original packaging to protect it from moisture.
Keep at room temperature, ideally below 30°C.
Avoid exposure to direct sunlight or high heat.
Always keep this medicine out of reach of children.
Use Mirabig Tablet before the expiration date printed on the pack.

Since you're managing an overactive bladder with Mirabig Tablet, try to limit your caffeine intake. Caffeine can stimulate your bladder and increase the urge to urinate.
Engage in regular pelvic floor exercises. This can strengthen your bladder muscles and help reduce symptoms like urinary urgency and incontinence.

Fact Box

Drug Category	Beta-3 Adrenergic Agonist
Therapeutic Category	Urinary Antispasmodic
Available Dosage Types	Tablet ER
Habit Forming	No
Ailment	Overactive Bladder, Urinary Urgency, Urge Incontinence

What is Mirabig Tablet used for?

Mirabig Tablet is used to manage the symptoms of overactive bladder in adults, including urinary urgency, frequency, and involuntary leakage.

How does Mirabig Tablet work?

This medicine works by stimulating receptors in the bladder muscle to relax it, increasing bladder capacity, and reducing symptoms of an overactive bladder.

How should I take Mirabig Tablet?

You should take it with water, with or without food. The tablet should be swallowed whole and not chewed, divided, or crushed. Always follow your doctor's instructions for taking Mirabig Tablet.

Can I take Mirabig Tablet if I have kidney or liver problems?

If you have severe kidney issues or moderate liver issues, you should consult your doctor before taking this medicine.

Are there any side effects of Mirabig Tablet?

Yes, some common side effects include high blood pressure, nasal inflammation, urinary tract infections, and headaches.

Can I take other medicines while using Mirabig Tablet?

Some medicines such as ketoconazole, itraconazole and clarithromycin may interact with Mirabig Tablet. Always inform your doctor about all medications, herbal products, and supplements you are currently taking.

Can pregnant or nursing women use Mirabig Tablet?

For pregnant or nursing women, this medicine should only be used if the potential benefit outweighs the potential risk. Always consult your doctor before use.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 9 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

MSN House, Plot No: C-24, Industrial Estate, Sanathnagar, Hyderabad, Telangana 500018

Country of origin: INDIA

References

Astellas Pharma US, Inc. (2012). HIGHLIGHTS OF PRESCRIBING INFORMATION [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/202611s000lbl.pdf
Betmiga. (n.d.). Betmiga Summary of product characteristics. https://www.ema.europa.eu/en/documents/product-information/betmiga-epar-product-information_en.pdf
Dawood, O., & El-Zawahry, A. (2023, August 28). Mirabegron. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK538513/
PubChem. (n.d.). Mirabegron. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Mirabegron
Mirabegron: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB08893

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