Miragron 25 Mg Tablet Er 10

Miragron Er 25 Tablet 10

Steris Healthcare

Strip of 10 Units

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Composition

Mirabegron (25 Mg)

Miragron ER 25 Tablet is primarily used to manage symptoms of overactive bladder (OAB), a condition that affects adults. This medicine belongs to the class of beta-3 adrenergic receptor agonists.

In addition to the main use, this medicine also helps reduce the frequency and intensity of involuntary bladder contractions, thereby helping to alleviate the sudden urge to urinate, frequent urination, and accidental urine leakage, which are associated with OAB.

Before starting on this medication, it is important that you consult your doctor who will guide you on the right dosage and frequency. Make sure to inform your doctor about your medical history and current medications as they may impact how this tablet works for you. If you experience any side effects while taking this medicine, report them to your doctor immediately. Remember, it's crucial to continue taking this medicine for the duration recommended by your doctor for optimal benefits.

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Miragron ER 25 Tablet is used for the following:

Managing symptoms of overactive bladder (OAB)
Decreasing urinary urgency in adults
Reducing frequent urination in adults
Managing urge urinary incontinence in adults

Directions for Use of Miragron Er 25 Tablet 10

Here are some instructions for taking Miragron ER 25 Tablet:

Swallow the tablet whole with a glass of water.
Do not crush, chew, or divide this medicine.
It can be taken with or without food, as per your convenience.
Never take more than the recommended dose without consulting your doctor.
Do not stop using this medicine without first speaking to your doctor.

Miragron ER 25 Tablet is taken orally.

Side Effects of Miragron Er 25 Tablet 10

Taking Miragron ER 25 Tablet might lead to the following side effects:

Hypertension: This is a medical term for high blood pressure.
Nasopharyngitis: This refers to inflammation of the nasal passages and throat.
Urinary Tract Infection: Commonly known as UTI, this is an infection that affects your urinary system.
Headache
Constipation
Dry mouth
Tachycardia: This term refers to unusually fast heart rate, and occurs when used with solifenacin.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Miragron ER 25 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Constipation: Consider increasing your fibre intake and staying well-hydrated.
Dry mouth: Sipping water regularly throughout the day can help manage this side effect.

Miragron ER 25 Tablet contains mirabegron (25 mg), which acts on your body in the following ways:

Stimulates Beta-3 Adrenergic Receptors: Mirabegron works by selectively stimulating the beta-3 adrenergic receptors found in your bladder muscle.
Increases Bladder Capacity: The activation of these receptors leads to relaxation of the bladder muscle. This increase in relaxation allows your bladder to hold more urine.
Reduces Bladder Contractions: By increasing bladder capacity, mirabegron effectively reduces the frequency and intensity of involuntary bladder contractions, thus reducing symptoms of overactive bladder.

Pregnancy

If you are pregnant, caution is advised while taking Miragron ER 25 Tablet. To ensure the safety of both you and your unborn child, it is best to consult your doctor before starting this medicine.

Breastfeeding

While breastfeeding, it's important to be cautious with Miragron ER 25 Tablet. As mirabegron could be excreted in breast milk, consultation with your doctor is advised.

Alcohol

It's always a good idea to discuss alcohol consumption with your doctor when starting this medicine.

Liver

For those with moderate liver impairment, the use of Miragron ER 25 Tablet should not exceed 25 mg once daily. If you have severe liver problems, this medicine is not recommended. Your doctor can provide further guidance.

Kidney

If you have severe renal impairment, it's recommended that you limit the dose of Miragron ER 25 Tablet to 25 mg once daily. The medicine is not recommended for individuals with end-stage renal disease. Consultation with your doctor is necessary if you have kidney health issues.

Using Machines & Driving

Miragron ER 25 Tablet has no specific impact on driving or operating machinery. However, it's always wise to understand how the medicine affects you before engaging in such activities.

Allergy

Some people may experience severe allergic reactions to Miragron ER 25 Tablet. If you notice symptoms like difficulty breathing or skin rash, seek immediate medical help.

Children

Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients can take Miragron ER 25 Tablet, but they should do so under medical supervision as they may be more susceptible to its side effects. It's particularly important to exercise caution if the patient is above 70 years of age, as they might have liver and kidney issues or might be on other medications. Your doctor will guide you based on your health status.

Interactions of Miragron Er 25 Tablet 10

Drug-Drug Interactions

Miragron ER 25 Tablet interacts with the following medicines:

CYP2D6 substrates: Mirabegron, present in this medicine, moderately inhibits the CYP2D6 enzyme. So, if you are taking medicines like metoprolol or desipramine, which are metabolised by this enzyme, monitoring and dose adjustments might be needed.
Medicines with a narrow therapeutic index: If you're taking medicines like thioridazine, flecainide, or propafenone (which have a narrow therapeutic index and are metabolised by CYP2D6), you may need close monitoring and possible dose adjustments.
Digoxin: When starting treatment with digoxin alongside Miragron ER 25 Tablet, the lowest dose of digoxin should be used and serum digoxin levels monitored to adjust the dose.

Drug-Food Interactions

There are no known specific food interactions with Miragron ER 25 Tablet. You can take this medicine with or without food as per your convenience.

Drug-Disease Interactions

Miragron ER 25 Tablet interacts with the following diseases:

Hypertension: As this medicine can increase blood pressure, it's important to monitor blood pressure regularly if you have hypertension. This medication is not advised for patients with severe uncontrolled hypertension.
Severe Renal Impairment: If you have severe renal impairment, your doctor will likely limit your dosage to 25 mg once daily. The medicine is not recommended for patients with end-stage renal disease.
Moderate to Severe Hepatic Impairment: Use of Miragron ER 25 Tablet is not recommended if you have moderate to severe hepatic impairment.

Daily Dose

It's crucial that you take Miragron ER 25 Tablet as directed by your doctor. The dosage will depend on factors like your condition's severity and how your body responds to the medicine. For specific instructions, please read the package insert.

Over Dose

If you accidentally take more than the prescribed dose of Miragron ER 25 Tablet, you might experience symptoms like an increased heart rate or high blood pressure. If you notice any unusual symptoms, inform your doctor.

Missed Dose

In case you forget to take your dose of Miragron ER 25 Tablet, take it as soon as you remember. However, if it is nearly time for the next dose, skip the missed one and continue with your regular schedule. Always consult your doctor before making any changes to your dosage.

Store Miragron ER 25 Tablet at room temperature, ideally between 20°C and 25°C.
Short-term exposure to temperatures from 15°C to 30°C is acceptable.
Keep the medicine in its original packaging to shield it from light and moisture.
Always keep this medicine out of reach of children.
Ensure you use the medicine before its expiry date.

Stay well-hydrated: Drinking plenty of water can help manage symptoms of overactive bladder, as it encourages regular, controlled urination rather than sudden urges.
Limit caffeine intake: Caffeine can irritate the bladder and increase urinary urgency. Opt for decaffeinated beverages where possible or reduce your overall caffeine consumption to help manage your overactive bladder symptoms more effectively.

Fact Box

Drug Category	Beta-3 Receptor Agonist
Therapeutic Category	Urinary Disorder Medication
Available Dosage Types	Extended Release Tablet
Habit Forming	No
Ailment	Overactive Bladder, Urinary Urgency, Urge Incontinence

What is Miragron ER 25 Tablet used for?

This medicine is used to manage symptoms of an overactive bladder, such as sudden urges to urinate, frequent urination, and urinary incontinence.

How does Miragron ER 25 Tablet work?

It stimulates certain receptors in the bladder muscle, leading to muscle relaxation, increased bladder capacity, and reduced frequency of bladder contractions.

How should I take Miragron ER 25 Tablet?

You should swallow one tablet whole with water, once daily. It can be taken with or without food. Do not chew, divide or crush the tablet.

Can I take Miragron ER 25 Tablet if I have high blood pressure?

Mirabegron can increase blood pressure, therefore if you have high blood pressure, consult your doctor before taking this medicine.

Are there any side effects of taking Miragron ER 25 Tablet?

Yes, common side effects include hypertension, a common cold (nasopharyngitis), urinary tract infections, headaches and constipation.

Can I take other medicines while using Miragron ER 25 Tablet?

Some medicines may interact with mirabegron. Always inform your doctor about all the medicines you are currently taking.

How should I store my Miragron ER 25 Tablet?

Store it at room temperature between 20°C to 25°C in its original package protected from light and moisture.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

References

Astellas Pharma US, Inc. (2012). HIGHLIGHTS OF PRESCRIBING INFORMATION [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/202611s000lbl.pdf
Betmiga. (n.d.). Betmiga Summary of product characteristics. https://www.ema.europa.eu/en/documents/product-information/betmiga-epar-product-information_en.pdf
Dawood, O., & El-Zawahry, A. (2023, August 28). Mirabegron. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK538513/
PubChem. (n.d.). Mirabegron. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Mirabegron
Mirabegron: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB08893

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