Naprostrong D 250 Mg Tablet 10

Naprostrong D 250 Tablet 10

Mankind Pharmaceuticals Ltd.

Strip of 10 Units

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MRP ~~₹70~~

₹40.85

₹7.00/Units

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Composition

Domperidone (10 Mg) + Naproxen (250 Mg)

Naprostrong D 250 Tablet 10 is primarily used for managing migraines and the related symptoms including severe headaches, nausea, and vomiting. This medication is a combination medicine that falls under the categories of antiemetic and nonsteroidal anti-inflammatory drugs (NSAIDs).

In addition to this, this tablet assists in preventing bouts of migraines and the resultant queasiness. Furthermore, it helps manage the inflammation and fever often accompanying migraines.

It's advisable to take this medicine as directed by your doctor. Do inform your doctor about any existing medical conditions or medications you are currently on before starting with this tablet. If you experience any side effects while on this medication, promptly inform your doctor. For the best results, continue taking the medicine for the entire duration prescribed by your doctor.

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Naprostrong D 250 Tablet 10 is used for the following:

Prevention of migraines.
Management of severe headaches.
Reduction of nausea during migraines.
Control of vomiting during migraines.

Directions for Use of Naprostrong D 250 Tablet 10

Follow these instructions while taking Naprostrong D 250 Tablet 10:

Swallow the tablet whole with a glass of water. Avoid crushing or chewing the tablet.
You can take this medicine with or without food, as per your preference.
Try to take the medicine at the same time each day to maintain consistent levels in your body.
Always remember not to exceed the recommended dose without consulting your doctor.

Naprostrong D 250 Tablet 10 is taken orally.

Side Effects of Naprostrong D 250 Tablet 10

Taking Naprostrong D 250 Tablet 10 may lead to some common side effects such as:

Headache
Dizziness
Drowsiness
Dry mouth
Gastrointestinal disturbances: These can include symptoms like nausea, vomiting, abdominal pain, and diarrhoea.
Rash

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Naprostrong D 250 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some general guidelines for managing common side effects:

Drowsiness: If you feel sleepy after taking this medicine, consider taking it at bedtime to avoid daytime drowsiness.
Gastrointestinal disturbances: If you notice stomach upset, try taking Naprostrong D 250 Tablet 10 with food.

Naprostrong D 250 Tablet 10 consists of two active ingredients:

Domperidone (10 mg): As an antiemetic medication, domperidone works by blocking dopamine receptors in a specific area of the brain known as the chemoreceptor trigger zone (CTZ). This action helps reduce feelings of nausea and vomiting. Additionally, domperidone enhances the movement of food through the stomach and upper intestine which prevents reflux.
Naproxen (250 mg): This NSAID has analgesic, anti-inflammatory and fever-reducing properties. Naproxen works by inhibiting an enzyme called cyclooxygenase (COX). This enzyme is involved in producing prostaglandins - chemicals responsible for pain, inflammation, and fever. By reducing prostaglandin production, naproxen effectively manages these symptoms associated with migraines.

Pregnancy

Caution is advised while taking Naprostrong D 250 Tablet 10 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Naprostrong D 250 Tablet 10 should not be used if you are breastfeeding. It is important to discuss with your doctor about the potential risks and benefits.

Alcohol

You should avoid drinking alcohol while taking Naprostrong D 250 Tablet 10 as it can increase the risk of stomach bleeding.

Liver

If you have liver problems, Naprostrong D 250 Tablet 10 should be used with caution. This medicine could affect your liver function. Always discuss your liver health with your doctor before starting this medicine.

Kidney

Naprostrong D 250 Tablet 10 should be used with caution if you have a history of kidney problems. Your doctor will guide you based on your health status.

Using Machines & Driving

Naprostrong D 250 Tablet 10 may cause dizziness or drowsiness. If you experience these side effects, avoid driving or operating heavy machinery.

Allergy

If you are allergic to domperidone or naproxen, the active ingredients in Naprostrong D 250 Tablet 10, do not take this medicine. Inform your doctor about any known allergies before starting this medication.

Children

Naprostrong D 250 Tablet 10 is not recommended for children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients may be more susceptible to the side effects of Naprostrong D 250 Tablet 10 and should take it under medical supervision. Caution is advised if patients are above 70 years of age who might also have liver and kidney issues, and might be on other medicines. Your doctor will guide you based on your health status.

Interactions of Naprostrong D 250 Tablet 10

Drug-Drug Interactions

Naprostrong D 250 Tablet 10 interacts with the following medicines:

Antifungals: Medicines like ketoconazole may interact with Naprostrong D 250 Tablet 10, potentially increasing plasma concentrations and adverse effects due to domperidone.
Anticoagulants: Medications such as warfarin may interact with Naprostrong D 250 Tablet 10, leading to enhanced effects or increased risk of bleeding due to naproxen.
Diuretics: When taken with Naprostrong D 250 Tablet 10, diuretics like furosemide can alter the effectiveness of naproxen.

Drug-Food Interactions

No specific food interactions have been identified for Naprostrong D 250 Tablet 10.

Drug-Disease Interactions

Naprostrong D 250 Tablet 10 interacts with the following diseases:

Gastrointestinal Ulcers: If you have a history of gastrointestinal ulcers, the use of naproxen in Naprostrong D 250 Tablet 10 could cause exacerbation of your condition.
Bleeding Disorders: Naproxen in Naprostrong D 250 Tablet 10 might increase bleeding risks if you have a bleeding disorder.
Severe Hepatic or Renal Impairment: The active ingredients in Naprostrong D 250 Tablet 10, namely domperidone and naproxen, are metabolised in the liver and excreted via the kidneys, so the medicine should be used with caution if you have severe liver or kidney impairment.
Cardiac Arrhythmias or Congenital Long QT Syndrome: Domperidone in Naprostrong D 250 Tablet 10 may cause QT prolongation, hence should be avoided if you have these conditions.

Daily Dose

Your daily dosage of Naprostrong D 250 Tablet 10 should be as your doctor recommends. It could vary depending on your personal health condition and how you respond to the medication. Always follow the prescribed dosage and never increase it without consulting your doctor.

Over Dose

If you accidentally take more Naprostrong D 250 Tablet 10 than recommended, you might feel drowsy, dizzy, or have a headache. You might also experience stomach disturbances such as nausea or diarrhoea. In such cases, inform your doctor about the situation.

Missed Dose

If you forget to take your Naprostrong D 250 Tablet 10, take it as soon as you remember. But if it's nearly time for your next dose, just skip the missed one and continue with your usual schedule. Do not take an additional dose without speaking to your doctor first.

Store Naprostrong D 250 Tablet 10 at room temperature, ideally below 25°C.
Keep it in a dry place, away from excessive light and moisture.
The original container is the best storage option; ensure it's tightly closed.
Always keep this medicine out of reach of children.
Use Naprostrong D 250 Tablet 10 before the expiry date mentioned on the pack.

Migraine can sometimes be triggered by certain foods. Try to identify any such triggers in your diet and minimise their intake. This could include items like aged cheese, processed meats, or even chocolate.
Regular physical activity can help manage migraines. Aim for moderate-intensity exercises like brisk walking or cycling for about half an hour most days of the week.

Fact Box

Drug Category	Dopamine Antagonist, NSAID
Therapeutic Category	Antiemetic, Analgesic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Migraines, Nausea, Vomiting

What is Naprostrong D 250 Tablet 10 used for?

Naprostrong D 250 Tablet 10 is primarily used to manage migraines and associated symptoms like severe headaches, nausea, and vomiting.

How does Naprostrong D 250 Tablet 10 work?

The medicine combines domperidone and naproxen, which block certain chemicals in the body causing pain, inflammation, fever, nausea, and vomiting.

When should I take Naprostrong D 250 Tablet 10?

You should take the medicine as advised by your doctor. It can be taken with or without food.

What are the common side effects of Naprostrong D 250 Tablet 10?

Common side effects include headache, dizziness, drowsiness, dry mouth, gastrointestinal disturbances (nausea, vomiting), and rash.

Can I take other medicines along with Naprostrong D 250 Tablet 10?

Some medicines may interact with Naprostrong D 250 Tablet 10. It's important to inform your doctor about all the medicines you're currently taking.

How should I store Naprostrong D 250 Tablet 10?

Store it at room temperature, in a dry place protected from light and moisture. Keep it out of reach of children.

Who shouldn't take Naprostrong D 250 Tablet 10?

Those allergic to domperidone or naproxen, have a history of gastrointestinal ulcers or bleeding disorders, or have severe liver or kidney problems should not take this medicine.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

208, Okhla Industrial Estate, Phase-III, New Delhi South Delhi DL 110020 IN

Country of origin: INDIA

References

Almatica. (2017). Highlights of prescribing information. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020353s034lbl.pdf
Naproxen: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00788
Food and Drug Administration. (2021). Domperidone IND packet (pp. 1–5). https://www.fda.gov/media/100064/download
Domperidone: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01184

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