Oflochem 400 Mg Tablet 10

Oflochem 400 Tablet 10

Zydus Healthcare Ltd

Strip of 10 Units

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MRP ~~₹282.8~~

₹141.12

₹28.28/Units

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Composition

Ofloxacin (400 Mg)

Strength:

200 MG 400 MG 100 MG

Oflochem 400 Tablet 10 is primarily used to manage bacterial infections. This medicine belongs to the class of antibiotics classified as fluoroquinolones.

This tablet is also used for various conditions, such as urinary tract infections, pneumonia, skin and soft tissue infections, and reproductive organ infections. However, it's crucial to note that it should not be used for viral infections.

Before starting this medicine, inform your doctor about any ongoing medications or pre-existing conditions you might have. If you experience any side effects while on this medication, inform your doctor. For optimal results, it's important to continue taking this for the duration prescribed by your doctor.

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Oflochem 400 Tablet 10 is used for the following:

Managing bacterial infections in the urinary tract
Controlling respiratory tract infections, including pneumonia
Handling skin and soft tissue infections caused by bacteria
Managing bacterial infections of the reproductive organs

Directions for Use of Oflochem 400 Tablet 10

Swallow the whole tablet with a glass of water.
Avoid crushing or chewing the tablet.
Keep a consistent schedule for taking this medicine, ideally around 12 hours apart.
Continue to take it for the entire course as prescribed by your doctor, even if symptoms improve earlier.

Oflochem 400 Tablet 10 is taken orally.

Oflochem 400 Tablet 10 may have the following common side effects:

Nausea
Vomiting
Stomach pain
Diarrhoea
Headache
Dizziness
Sleep disturbances
Vaginal itching or discharge

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Oflochem 400 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Try taking Oflochem 400 Tablet 10 with food or milk to reduce feelings of nausea.
Stomach pain: Consider taking this medicine after meals to lessen stomach discomfort.

Oflochem 400 Tablet 10 contains ofloxacin (400 mg), which works on the body as follows:

Inhibits Bacterial DNA Enzymes: Ofloxacin works by blocking two enzymes in bacterial DNA, gyrase and topoisomerase IV. These enzymes are vital for the bacteria as they help in DNA replication, transcription, repair, and recombination.
Disrupts Bacterial DNA Processes: By inhibiting these enzymes, ofloxacin disrupts essential DNA processes in bacterial cells, leading to their death. This action helps manage various bacterial infections effectively.

Pregnancy

Caution is advised while taking Oflochem 400 Tablet 10 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, caution is recommended when taking an Oflochem 400 Tablet 10. Consult your doctor to understand the potential risks and benefits.

Alcohol

While consuming alcohol, caution is advised when taking Oflochem 400 Tablet 10. It's advisable to discuss this with your doctor before starting this medicine.

Liver

If you have liver problems, discuss them with your doctor before starting Oflochem 400 Tablet 10. This medicine may affect liver function.

Kidney

Caution is advised before taking Oflochem 400 Tablet 10 if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

Oflochem 400 Tablet 10 may cause dizziness or sleepiness. You should not drive or operate machinery until you know how this medicine affects you.

Allergy

Please inform your doctor if you have any known allergies to ofloxacin or other fluoroquinolone antibiotics before starting Oflochem 400 Tablet 10.

Children

Oflochem 400 Tablet 10 should only be given to children under 18 years of age under medical supervision. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Oflochem 400 Tablet 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Oflochem 400 Tablet 10 interacts with the following medicines:

Supplements: Medicines and dietary supplements containing iron, zinc, or magnesium can interfere with the absorption of Oflochem 400 Tablet 10. Some specific examples include aluminium hydroxide and ferrous sulphate.
Anti-ulcer medicines: Medications like sucralfate can bind to Oflochem 400 Tablet 10 in the stomach, reducing its effectiveness.
Blood thinners: Oflochem 400 Tablet 10 can potentially increase the effect of blood thinners like warfarin, leading to an increased risk of bleeding.

Drug-Food Interactions

Oflochem 400 Tablet 10 does not have any known significant interactions with specific foods.

Drug-Disease Interactions

Oflochem 400 Tablet 10 interacts with the following diseases:

Kidney Disease: If you have kidney disease, your body may process this medicine more slowly, leading to more side effects.
Liver Disease: In patients with liver disease, the metabolism of Oflochem 400 Tablet 10 may be affected, requiring dose adjustments.
Seizures: Oflochem 400 Tablet 10 may increase the risk of seizures or worsen seizures in people who already have this condition.
Myasthenia Gravis: This medicine may worsen muscle weakness in individuals with myasthenia gravis.

Daily Dose

Take the recommended dose of Oflochem 400 Tablet 10 as prescribed by your doctor. The dosage may vary based on your individual health status and how you respond to the medication. It's crucial to adhere to the recommended dosage and not modify it without consulting your doctor.

Over Dose

If you accidentally take more than the prescribed dose of Oflochem 400 Tablet 10, you may experience symptoms such as drowsiness or nausea. In this situation, it is important to inform your doctor and follow their advice.

Missed Dose

If you forget to take a dose of Oflochem 400 Tablet 10, take it as soon as you remember. However, if it's nearly time for your next dose, just skip the missed one and continue with your regular schedule. Do not increase your dosage without speaking with your doctor.

Store an Oflochem 400 Tablet 10 at room temperature, below 30°C.
Protect it from direct light and avoid damp places, maintaining a dry environment.
Always keep out of reach of children.

Increase your water intake for those managing urinary tract infections with Oflochem 400 Tablet 10; this can help flush out bacteria.
If you're taking Oflochem 400 Tablet 10 for respiratory tract infections such as pneumonia, refrain from smoking as it could further irritate your lungs and impede recovery.

Fact Box

Drug Category	Antibacterial
Therapeutic Category	Antibiotic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Urinary Tract Infections, Pneumonia, Skin and Soft Tissue Infections

What is Oflochem 400 Tablet 10 used for?

Oflochem 400 Tablet 10 is used to manage a range of bacterial infections, including those of the urinary and respiratory tracts, skin and soft tissues, and reproductive organs.

How does Oflochem 400 Tablet 10 work?

It contains ofloxacin, a fluoroquinolone antibiotic that inhibits essential enzymes in bacteria, disrupting their DNA processes and leading to cell death.

Can I take Oflochem 400 Tablet 10 with food?

Yes, you can take Oflochem 400 Tablet 10 with or without food. However, for best efficacy, it's recommended to take it consistently each day.

What should I do if I miss a dose of Oflochem 400 Tablet 10?

Take the missed dose as soon as you remember unless it's nearly time for the next one. Never double up on doses to compensate.

What are some common side effects of Oflochem 400 Tablet 10?

Common side effects may include nausea, vomiting, stomach pain, diarrhoea, headache, dizziness, sleep disturbances and vaginal itching or discharge. Please consult your doctor if these side effects persist.

Is it safe to use Oflochem 400 Tablet 10 during pregnancy?

Pregnant women should consult their doctor before taking Oflochem 400 Tablet 10 to understand any potential risks or adjustments needed.

How should I store Oflochem 400 Tablet 10?

Store this tablet at room temperature, keeping them away from direct light and moisture.

Certified Content

Written by

Dr Vatsalya D Ghanekar

Medical Content Writer | 5 years

MD Ayurveda

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

Zydus Tower, Satellite Cross Roads, Sarkhej - Gandhinagar Highway, Ahmedabad Ahmedabad GJ 380015 IN

Country of origin: INDIA

References

PubChem. (n.d.). Ofloxacin. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/4583
Ofloxacin: uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01165
U.S. National Library of Medicine. (2022). Ofloxacin. MedlinePlus. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a691005.html
U.S. Food and Drug Administration. (2007). Ofloxacin tablets, USP. FDA. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/019735s058lbl.pdf
Graham, D. B., & Tripp, J. (2023, June 26). Ofloxacin. StatPearls NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK549837/

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