Oflomac Oz 200500 Mg Tablet 10

Oflomac Oz Tablet 10

Macleods Pharmaceuticals Pvt.ltd

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Composition

Ofloxacin (200 Mg) + Ornidazole (500 Mg)

Oflomac Oz tablet is a combination medication that contains two active ingredients: Ofloxacin and ornidazole. Ofloxacin belongs to a category of antibiotics called fluoroquinolones, while ornidazole belongs to a class of antibiotics called nitroimidazoles. Together, these two medications prevent the growth and spread of bacteria and parasites in the body. It effectively treats many bacterial infections in the teeth, lungs, gastrointestinal, urinary, and genital tract.

Ofloxacin, a fluoroquinolone antibiotic that inhibits bacterial DNA production, eventually leading to cell death, is one of the active components of Oflomac Oz tablets. The other active component is ornidazole, a nitroimidazole antibiotic that alters the DNA structure of bacteria and parasites, eventually killing them.

It may also interact with other medications or underlying medical conditions. Talking to a doctor before taking the Oflomac Oz tablet is essential to ensure it is safe and effective for your needs.

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Oflomac Oz tablet is commonly prescribed to treat a wide range of bacterial and protozoal infections.

Gastrointestinal infections: The Oflomac Oz tablet effectively treats gastrointestinal infections such as acute diarrhoea and bacterial gastroenteritis caused by Salmonella, Shigella, and Campylobacter species.
Amoebiasis: Oflomac Oz tablet effectively treats amoebic liver abscess and intestinal amoebiasis caused by Entamoeba histolytica.
Giardiasis: Oflomac Oz tablet is an effective treatment option for giardiasis, a common intestinal protozoal infection caused by Giardia lamblia.

It is important to note that the Oflomac Oz tablet should be taken only as prescribed by a healthcare professional. All instructions and precautions should be followed to ensure its safe and effective use.

Directions for Use of Oflomac Oz Tablet 10

The Oflomac Oz tablet should be swallowed whole and not crushed or chewed.

The Oflomac Oz tablet can be taken with or without food.

Follow your doctor's instructions for taking the Oflomac Oz tablet, including the treatment dosage, frequency, and duration.

Oflomac Oz tablet is taken orally.

The following are the side effects of the Oflomac Oz tablet:

Nausea: Nausea is a typical side effect of the Oflomac Oz tablet. It is a feeling of discomfort in the stomach that may be accompanied by an urge to vomit.
Vomiting: A common side effect of the Oflomac Oz tablet is vomiting. It is forcefully expelling the stomach's contents through the mouth.
Diarrhoea: Oflomac Oz tablet may cause diarrhoea, a common side effect. It is characterised by loose, watery stools that occur more frequently than usual.
Abdominal pain: Abdominal pain is a common side effect of the Oflomac Oz tablet. It is a pain or discomfort in the area between the chest and the pelvis.
Headache: Frequent headache is a side effect of the Oflomac Oz tablet, causing pain or discomfort in the head. Headache may accompany other symptoms such as nausea, vomiting, photophobia and increased sensitivity to sound.
Dizziness: Dizziness is a typical side effect of the Oflomac Oz tablet. It may cause lightheadedness or unsteadiness that may accompany other symptoms, such as nausea and sweating.

Managing the Side Effects:

Most of the side effects are temporary and harmless, and get resolved by discontinuing the tablet. These may not require medical attention. To combat abdominal discomfort, take this tablet with food. If you experience severe or persistent side effects from this tablet, consult your doctor.

The combination of ofloxacin and ornidazole in Oflomac Oz tablet provides a broad spectrum of antimicrobial activity against various bacterial and protozoal infections. Ofloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA replication and repair, resulting in their eventual death. It is effective against many bacteria that cause respiratory, urinary, and gastrointestinal infections.

Ornidazole is a nitroimidazole antibiotic that disrupts the DNA structure of protozoal and anaerobic bacteria. It effectively inhibits their growth and death. Using Ofloxacin and ornidazole can also help reduce antibiotic resistance by targeting multiple bacterial and protozoal activity pathways.

Moreover, these ingredients have other medicinal properties as well. For instance, ofloxacin has anti-inflammatory and immunomodulatory effects, making it helpful in treating inflammatory conditions such as rheumatoid arthritis. Ornidazole has antioxidant and anti-inflammatory effects, which help treat periodontitis and inflammatory bowel disease. Nevertheless, it is crucial to follow all instructions and precautions a healthcare provider provides when taking this medication to ensure its safe and effective use.

Pregnancy

Strictly not recommended for using Oflomac Oz tablet in pregnancy. The potential side effects of the Oflomac Oz tablet can harm the health of the mother and the foetus. If you are planning pregnancy, consult your doctor before taking the Oflomac Oz tablet.

Breastfeeding

Oflomac Oz tablet is not advised for breastfeeding women because the effects of these tablets on breast milk and nursing infants are not well-known. Consult your doctor for advice before taking the Oflomac Oz tablet.

Alcohol

Avoid drinking alcohol while taking the Oflomac Oz tablet as it may worsen your symptoms of sleepiness, dizziness and eyesight problems.

Liver

Oflomac Oz tablet should be taken cautiously in patients with liver disease. Individuals with liver disease may have difficulty processing medications, which can increase the likelihood of adverse side effects. Consult your doctor for advice before taking the Oflomac Oz tablet.

Kidney

Oflomac Oz tablet should be taken cautiously in patients with kidney disease or problems. Consult your doctor for advice before taking the Oflomac Oz tablet.

Using Machines & Driving

After taking the Oflomac Oz tablet, you should not drive or operate machines if you feel dizzy, tired, sleepy, temporary loss of consciousness, less alert, have a spinning sensation in the head, impaired vision, shivering, abnormal body movements and seizure/fits.

Allergy

Do not take the Oflomac Oz tablet if allergic to Ofloxacin or Ornidazole. Also, inform your doctor if you are allergic to other quinolone antibiotics, such as ciprofloxacin and norfloxacin.

Children

Oflomac Oz tablet is not suggested for use in children and adolescents under 18. Consult your child's doctor for advice.

Older Patients

Oflomac Oz tablet should be used cautiously in elderly patients. Your doctor will decide the dose, duration and frequency of the Oflomac Oz tablet depending on the severity of your existing condition and other comorbid conditions.

Drug-Drug Interactions

Oflomac Oz tablet can interact with medications, including:

Anticoagulants: Oflomac Oz tablet may increase the effects of anticoagulant medications, such as warfarin, leading to an increased risk of bleeding. Patients taking anticoagulant medications should closely monitor their blood clotting time while taking the Oflomac Oz tablet.
Anti-arrhythmic medications: Drugs such as quinidine or amiodarone may increase the risk of arrhythmias when taken with an Oflomac Oz tablet. Patients given anti-arrhythmic drugs should closely check their heart rhythm when taking the Oflomac Oz tablet.
Nonsteroidal anti-inflammatory drugs (NSAIDs): Drugs like ibuprofen, aspirin or naproxen, when taken with Oflomac Oz tablet, may increase the risk of seizures.
Theophylline: Oflomac Oz tablet may increase the effects of theophylline, a medication used to treat asthma and other respiratory conditions.
Antibiotics: Azithromycin, Trimethoprim, Sulfamethoxazole, Metronidazole, and Erythromycin may increase the risk of toxicity in the body if taken along with the Oflomac Oz tablet.
Anti-diabetic: Metformin, when used with Oflomac Oz tablet, may produce blood sugar fluctuations and lactic acidosis, an uncommon but severe disease.
Diuretic drugs: When taken with the Oflomac Oz tablet, Furosemide can increase kidney toxicity and lead to electrolyte imbalances such as low potassium and magnesium levels.
Bronchodilators: If taken with the Oflomac Oz tablet, Albuterol can increase the risk of cardiovascular side effects. Albuterol can cause tachycardia (increased heart rate) and arrhythmias (irregular heart rhythms).

Drug-Disease Interactions

Oflomac Oz tablet can interact with diseases, including:

Colitis: Ofloxacin has been associated with inflammation in the colon's lining caused by a bacterial infection.
Tendonitis: Fluoroquinolones, including Ofloxacin, have increased the risk of tendonitis and tendon rupture.
Seizure disorders: Oflomac Oz tablet may raise the probability of seizures in people with a history of seizure disorders. Patients with a history of seizure disorders should be cautious when taking the Oflomac Oz tablet.
Crystalluria: Ofloxacin can cause crystalluria, forming crystals in the urine. Patients with a history of kidney stones or other conditions that increase the risk of crystalluria should use Oflomac Oz tablets cautiously.
Liver and kidney disease: People with liver or kidney illness should use the Oflomac Oz tablet cautiously. Dose adjustments may be necessary based on the individual's liver or kidney function level.
Myasthenia gravis: Oflomac Oz tablet may aggravate symptoms of myasthenia gravis, which leads to muscle weakness and fatigue. Patients with myasthenia gravis should be cautious when taking the Oflomac Oz tablet.
Diabetes: Ofloxacin, one of the active ingredients in Oflomac Oz tablets, has been associated with a raised risk of hypoglycemia (low blood sugar) in patients with diabetes.

Daily Dose

The recommended daily dose of Oflomac Oz tablet is once daily, with or without food, as directed by your doctor. The dosage may change based on individual factors such as the severity of the condition and response to treatment. It is crucial to follow the prescribed dosage and not exceed it without consulting your doctor.

Over Dose

If you or someone else takes an excessive amount of Oflomac Oz tablet by accident, it is essential to take immediate medical attention from your doctor or nearby hospital. Symptoms of an overdose include confusion, faintness, loss of awareness, seizure or fit, and nausea.

Missed Dose

If you forget to take a medication dosage, do so immediately. Ignore the missed dose and continue your usual dosing schedule if it is time for your next dose. Never double up on your medication to make up for a missed dosage. It is advised not to skip any antibiotic doses because doing so could cause treatment to fail.

Store the Oflomac Oz tablet intact in the packing it has been bought.
Please protect the Oflomac Oz tablet from extreme light and moisture.
Keep the Oflomac Oz tablet away from the reach of children.
Do not use the Oflomac Oz tablet after the expiry date has passed.

Consume a well-balanced diet that includes lean meat, fruits, vegetables, whole grains, legumes, and healthy fats.
Limit your intake of alcohol, sugary drinks, and processed high-fat foods.
Antibiotics can change the good bacteria in the stomach that aid in digestion. You are therefore encouraged to consume foods high in probiotics, including yoghurt or curd.
To stay hydrated, sip lots of water.
Get regular exercise; aim for 30 minutes or more each day of moderate activity.
Get enough rest and sleep every night, aiming for 7-9 hours.
Utilise relaxation methods to reduce stress, such as yoga, deep breathing, and meditation.
Limit your exposure to secondhand smoke and abstain from smoking and using tobacco.

Fact Box

Drug Category	Nitroimidazole and Fluoroquinolones
Therapeutic Category	Antibiotic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Bacterial and Parasitic Infections

Is Oflomac Oz used for loose motion?

Yes, Oflomac Oz is commonly used to treat loose motion or diarrhoea. It contains two active ingredients, namely ofloxacin and ornidazole, which can help fight against the bacteria and parasites that can cause diarrhoea.

Is Oflomac Oz a strong antibiotic?

Oflomac Oz is a broad-spectrum antibiotic, which means it can be effective against a wide range of bacterial and parasitic infections. However, whether or not Oflomac Oz is a "strong" antibiotic depends on the severity of the infection it is being used to treat and the individual's response to the medication.

Is Oflomac Oz good for stomach infections?

Yes, Oflomac Oz can effectively treat certain types of stomach infections. It can help fight against the bacteria and parasites that cause stomach infections, such as bacterial gastroenteritis, traveller's diarrhoea, and amoebiasis.

When is the best time to take Oflomac Oz?

Oflomac Oz should be taken as prescribed by a doctor or per the instructions on the packaging. Usually taken after meals with a full glass of water to reduce stomach upset. Take Oflomac Oz at the prescribed time to maintain its steady levels in your body. It is vital to complete the entire course of treatment, even if symptoms improve. Stopping prematurely can lead to a relapse of the infection and increase antibiotic resistance. If you have questions or concerns, consult with your doctor or pharmacist.

How many days should Oflox Oz be taken?

The exact duration of treatment and dosage will be determined by a doctor based on the individual patient's condition, medical history, and other factors.

Last Updated On 15 Feb. 2024 | 6:48AM (IST)

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 5 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 10 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

Atlanta Arcade, Marol Church Rd, Bori Colony, Vijay Nagar Colony West, Marol, Andheri East, Mumbai, Maharashtra 400059

Country of origin: INDIA

References

FLOXIN ® Tablets (Ofloxacin Tablets) Fda.Gov. (Retrieved November 2023). https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/019735s059lbl.pdf
Ofloxacin 400 mg Tablets - Summary of Product Characteristics (SmPC) - (emc). (n.d.). Org.uk. (Retrieved November 2023). https://www.medicines.org.uk/emc/product/8480/smpc
Ofloxacin. (n.d.). Medlineplus.Gov. (Retrieved November 2023). https://medlineplus.gov/druginfo/meds/a691005.html
Tripathi, K. D. (2019). Drugs for Constipation and Diarrhoea, Antiamoebic and Other Antiprotozoal Drugs . In Essentials of Medical Pharmacology (8th ed., pp. 763, 897). essay, Jaypee Brothers Medical Publishers.
PubChem. (n.d.). Ornidazole. Nih.Gov. Retrieved November 13, 2023, from https://pubchem.ncbi.nlm.nih.gov/compound/28061
CDSCO. (n.d.). Gov.In. (Retrieved November 2023). https://cdscoonline.gov.in/CDSCO/Drugs
ORNIDAZOLE 500mg & OFLOXACIN 200mg TABLET (ORNILOX) .(N.d.-p). Gov.Ng. (Retrieved November 2023). https://www.nafdac.gov.ng/wp-content/uploads/Files/SMPC/Feb2_2022/Ornilox-Tablets-Ofloxacin-200mg-and-Ornidazole-500mg-Tablets.pdf

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