Pentab D Tablet 10

Alembic Pharmaceuticals Ltd

STRIP of 15 Units
STRIP of 10 Units

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MRP ~~₹120.00~~

₹96.00

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Composition

Domperidone (10 Mg) + Pantoprazole (40 Mg)

Pentab-D Tablet is primarily used for managing symptoms of gastroesophageal reflux disease (GERD), a condition where stomach acid frequently flows back into the tube connecting your mouth and stomach, causing irritation. This combination medication belongs to the category of gastroprokinetic and antiemetic agents.

This tablet can also be used for relief from heartburn and acidity. The medicine has shown effectiveness in controlling the discomfort caused by these conditions, making digestion easier.

Always take this medicine as prescribed, and inform your doctor about any pre-existing conditions or ongoing medications before starting it. If you experience any side effects while taking this medication, notify your doctor promptly. It's important to continue taking the medicine for the duration prescribed by your doctor to achieve optimal results.

Pentab-D Tablet is used for the following:

Management of GERD
Relief from heartburn
Control of acidity
Aid in healing peptic ulcer disease
Management of Zollinger-Ellison syndrome

Directions for Use of Pentab D Tablet 10

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
Follow your doctor's advice on how often to take this medicine.

Pentab-D Tablet is taken orally.

Pentab-D Tablet may have the following common side effects:

Headache
Diarrhoea
Abdominal Pain
Nausea
Dizziness
Dry Mouth

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Pentab-D Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Try taking this tablet with food to reduce this effect.
Dry Mouth: Consider drinking plenty of water throughout the day if you experience dry mouth after taking this medicine.

Pentab-D Tablet constitutes two active ingredients:

Pantoprazole (40 mg): Falling under the class of proton pump inhibitors, pantoprazole works by blocking a system called H+/K+ ATPase enzyme in the gastric parietal cells that line your stomach and secrete gastric acid. This action effectively reduces gastric acid secretion, relieving symptoms of GERD, heartburn, and acidity and promoting the healing of gastric and duodenal ulcers.
Domperidone (10 mg): This ingredient acts as an antiemetic and prokinetic agent. It plays a vital role in blocking dopamine receptors in your gut and an area known as the chemoreceptor trigger zone, which is outside the blood-brain barrier. By doing so, domperidone helps reduce feelings of nausea and vomiting while increasing the movement of food through your digestive system.

Pregnancy

Caution is advised while taking this tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

This medicine should be used with caution when you are breastfeeding. Consult your doctor to understand the potential risks and benefits.

Alcohol

Drinking alcohol can potentially affect the effectiveness of this tablet. It's advisable to limit or avoid alcohol intake while taking this medicine.

Liver

If you have issues related to liver health, consult your doctor before starting this tablet.

Kidney

It's advisable to consult your doctor before using this tablet if you have any kidney-related conditions.

Using Machines & Driving

This tablet may cause drowsiness or dizziness, which could affect your ability to drive or operate machinery. If you experience such symptoms, it's safer not to drive or use heavy machinery until they subside.

Allergy

If you're allergic to any ingredient in this tablet, including domperidone or pantoprazole, do not take this medicine. Consult your doctor for an alternative prescription.

Children

This tablet is contraindicated for use in children below 18 years of age. Always consult your doctor before giving any medication to a child.

Older Patients

Older patients should take this tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Pentab-D Tablet interacts with the following medicines:

Anti-HIV Medications: Medicines like ritonavir and atazanavir may interact with Pentab-D Tablet, potentially increasing the risk of side effects due to higher levels of domperidone in the body.
Anti-fungal Medicines: When taken with Pentab-D Tablet, antifungal medicines such as ketoconazole and itraconazole can increase the concentration of domperidone in your body, enhancing its therapeutic and adverse effects.
Anti-coagulants: Medicines like warfarin may interact with Pentab-D Tablet, possibly altering the blood thinning effect.
Anti-hypertensive Medicines: The combined use of medicines like amlodipine or lisinopril with Pentab-D Tablet may increase the risk of low blood pressure.

Drug-Food Interactions

Certain foods may interact with Pentab-D Tablet. These include:

Grapefruit Juice: This beverage can increase the absorption of domperidone, potentially enhancing its effects and side effects.

Drug-Disease Interactions

Pentab-D Tablet interacts with the following diseases:

Liver Disease: If you have liver disease, be cautious as this medicine could worsen your condition.
Heart Rhythm Disorders: People with heart rhythm disorders should exercise caution while taking this tablet as it could potentially prolong QT intervals leading to serious heart complications.
Kidney Disease: This tablet should be used carefully in patients suffering from kidney diseases as pantoprazole is mainly eliminated through the kidneys and could lead to toxicity in case of impaired kidney function.

Daily Dose

It's crucial to take the Pentab-D Tablet as suggested by your doctor. The dosage can differ based on your condition and response to the medicine. Don't modify the dosage without consulting your doctor.

Over Dose

In case of an overdose, you might feel drowsy or confused or experience symptoms like dry mouth or headache. If these symptoms persist or worsen, please inform your doctor.

Missed Dose

If you forget to take your tablet, take it as soon as you remember. However, if it's nearly time for the next dose, skip the missed one and continue with your regular schedule. Never alter your dosage without consulting your doctor.

Store your Pentab-D Tablet in a cool, dry place away from direct sunlight and moisture.
The optimal storage temperature is below 30°C.
Keep the medicine out of the reach of children.
Always check the expiry date on the packet before use.

Try to limit your intake of spicy, fatty, or acidic foods. These can aggravate symptoms of GERD and heartburn.
Regular physical activity can help manage weight and reduce pressure on your abdomen, thus reducing GERD and heartburn symptoms. Ensure you include moderate exercise, like walking or cycling, in your daily routine.

Fact Box

Drug Category	Proton Pump Inhibitor, Antiemetic
Therapeutic Category	Gastrointestinal
Available Dosage Types	Tablet
Habit Forming	No
Ailment	GERD, Heartburn, Acidity

What is Pentab-D Tablet used for?

Pentab-D Tablet is used to manage gastrointestinal disorders such as GERD, heartburn, and acidity.

How does Pentab-D Tablet work?

It contains two active ingredients that work differently: Domperidone reduces nausea and increases gut movement, while Pantoprazole reduces stomach acid secretion.

How should I take Pentab-D Tablet?

The tablet should be swallowed whole with water, preferably 30 minutes before a meal. Always follow your doctor's instructions.

What are the side effects of Pentab-D Tablet?

Common side effects include headache, diarrhoea, abdominal pain, nausea, dizziness, and dry mouth. Consult your doctor if these persist or worsen.

Can I take Pentab-D Tablet during pregnancy?

Use during pregnancy should be considered only if the potential benefit outweighs the potential risk to the baby. Always consult your doctor.

Can I take other medicines with Pentab-D Tablet?

Some medicines, such as antifungals and antihypertensives, may interact with Pentab-D Tablet, affecting its effectiveness or causing side effects. Always inform your doctor about all medicines you're taking.

Should I avoid anything while taking Pentab-D Tablet?

Avoid crushing or chewing the tablet; it should be swallowed whole. Consult your doctor for more information.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Divya Chauhan

Medical Writer & Reviewer | 7 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

Alembic Road, Vadodara - 390 003, Gujarat,INDIA

Country of origin: INDIA

References

Pantoprazole: MedlinePlus drug information. (n.d.). MedlinePlus Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a601246.html
Pantoprazole: Medicine to lower stomach acid. (2018, August 29). nhs.uk. https://www.nhs.uk/medicines/pantoprazole/
Information about Domperidone. (2023, December 12). U.S. Food and Drug Administration. https://www.fda.gov/drugs/information-drug-class/information-about-domperidone
Domperidone 10mg tablets Patient information leaflet (PIL) (emc). (n.d.). electronic medicines compendium (emc). https://www.medicines.org.uk/emc/files/pil.556.pdf
Domperidone: Anti-sickness medicine for nausea and vomiting. (2023, April 12). nhs.uk. https://www.nhs.uk/medicines/domperidone/
Domperidone. (n.d.). DrugBank Online | Database for Drug and Drug Target Info. https://go.drugbank.com/drugs/DB01184

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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